MLKL mixed lineage kinase domain like pseudokinase

Information
Symbol
MLKL
Type
protein-coding
Description
mixed lineage kinase domain like pseudokinase
Entrez Gene ID
197259
Genome
hg19
Position
chr16:74,705,753-74,734,760
Genome
hg38
Position
chr16:74,671,855-74,700,862
MIM
615153 OMIM
HGNC
HGNC:26617 HGNC
Ensembl
ENSG00000168404 Ensembl
Links
NCBI Gene Cards OncoKB
Clinical Significance
MGeND ClinVar
Pathogenic 0 2
Benign 0 8
Likely benign 0 16
association 0 4
Uncertain significance 0 56
Ranking
ClinVar
0
0
0
82
4
Frequency
EXAC_EAS
EXAC_EAS
HGVD
HGVD
TOMMO
TOMMO
Gene
Position
EXAC_EAS
EXAC_EAS
HGVD
HGVD
TOMMO
TOMMO
Gene
Position
Disease area statistics
[No Data.]
Locus Zoom
Variants
Search Word
Target data :
MGeND data only
Category :
Search word :
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Variant name Gene AA change CDS Japanese
frequency		 TogoVar MGeND Genome ClinVar CIViC evidence DisGeNET entry COSMIC
occurrence		 Prediction
Entry Origin Type Annotation Entry Origin Annotation
Search Word
Target data :
MGeND data only
Category :
Search word :
Filtering :
Name MGeND Type Genome Size Chromosome Start Stop Ref Alt ClinVar Origin Entry CIViC evidence DisGeNET entry
Entry Origin Type Annotation
Search Word
Target data :
MGeND data only
Category :
Search word :
Filtering :
Name MGeND Type Genome Gene symbol Chromosome Genomic start Genomic stop Strand Ref Alt ClinVar Origin Entry CIViC evidence DisGeNET entry
Entry Origin Type Annotation
TypeID
SYNONYM hMLKL
MIM 615153 OMIM
HGNC HGNC:26617 HGNC
Ensembl ENSG00000168404 Ensembl
AllianceGenome HGNC:26617
DescrptionSourceLinks
IDGenomeChromosomeStartEndLength
ENST00000308807.12 hg38 chr16 74,671,855 74,700,862 29,008
ENST00000306247.11 hg38 chr16 74,671,855 74,700,790 28,936
ENST00000306247.11 hg19 chr16 74,705,753 74,734,688 28,936
ENST00000308807.12 hg19 chr16 74,705,753 74,734,760 29,008
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