SU5614
Information
- Drug Name
- SU5614
- Description
- Entry(CIViC)
- 2
CIViC
| Disease | Mutation | EL | ET | ED | CS | VO | TR | Pubmed | Links |
|---|---|---|---|---|---|---|---|---|---|
| acute myeloid leukemia |
FLT3 p.Asp835Tyr (p.D835Y) ( ENST00000241453.12 ) FLT3 p.Asp835Tyr (p.D835Y) ( ENST00000241453.12 ) |
D |
Predictive
|
Supports
|
Resistance | Somatic | 3 | 19318574 | Detail |
| acute myeloid leukemia | FLT3 ITD FLT3 ITD | D |
Predictive
|
Supports
|
Resistance | Somatic | 3 | 15626738 | Detail |
Annotation
| Description | Associated Genes | Associated Variants | Sensitivity | Supported | Source | Links |
|---|---|---|---|---|---|---|
| An in-vitro cell-based screening approach generate... | FLT3 |
FLT3 p.Asp835Tyr (p.D835Y) ( ENST00000241453.12 ) FLT3 p.Asp835Tyr (p.D835Y) ( ENST00000241453.12 ) |
Resitance or Non-Reponse | true | CIViC Evidence | detail |
| Ba/F3 cells with both FLT3-ITD and TKD mutations o... | FLT3 | FLT3 ITD FLT3 ITD | Resitance or Non-Reponse | true | CIViC Evidence | detail |