Pol I Inhibitor CX5461
Information
- Drug Name
- Pol I Inhibitor CX5461
- Description
- Entry(CIViC)
- 2
CIViC
Disease | Mutation | EL | ET | ED | CS | VO | TR | Pubmed | Links |
---|---|---|---|---|---|---|---|---|---|
breast cancer | BRCA1 LOSS-OF-FUNCTION BRCA1 LOSS-OF-FUNCTION | D |
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Sensitivity/Response |
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4 | 28211448 | Detail |
breast cancer | BRCA2 LOSS-OF-FUNCTION BRCA2 LOSS-OF-FUNCTION | D |
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Sensitivity/Response |
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4 | 28211448 | Detail |
Annotation
Description | Associated Genes | Associated Variants | Sensitivity | Supported | Source | Links |
---|---|---|---|---|---|---|
The authors show that in the CX-5461 and CX-3543, ... | BRCA1 | BRCA1 LOSS-OF-FUNCTION BRCA1 LOSS-OF-FUNCTION | Sensitivity | true | CIViC Evidence | detail |
The authors show that in the CX-5461 and CX-3543, ... | BRCA2 | BRCA2 LOSS-OF-FUNCTION BRCA2 LOSS-OF-FUNCTION | Sensitivity | true | CIViC Evidence | detail |