MEK Inhibitor TAK-733
Information
- Drug Name
- MEK Inhibitor TAK-733
- Description
- Entry(CIViC)
- 1
CIViC
| Disease | Mutation | EL | ET | ED | CS | VO | TR | Pubmed | Links |
|---|---|---|---|---|---|---|---|---|---|
| skin melanoma |
BRAF p.Leu637Ser (p.L637S) ( ENST00000288602.11, ENST00000496384.7, ENST00000644969.2, ENST00000646891.2 ) BRAF p.Leu637Ser (p.L637S) ( ENST00000646891.2, ENST00000644969.2, ENST00000288602.11, ENST00000496384.7 ) |
C |
Predictive
|
Supports
|
Sensitivity/Response | Somatic | 3 | 22798288 | Detail |
Annotation
| Description | Associated Genes | Associated Variants | Sensitivity | Supported | Source | Links |
|---|---|---|---|---|---|---|
| Case report of a 69 year old patient with metastat... | BRAF |
BRAF p.Leu637Ser (p.L637S) ( ENST00000288602.11, ENST00000496384.7, ENST00000644969.2, ENST00000646891.2 ) BRAF p.Leu637Ser (p.L637S) ( ENST00000646891.2, ENST00000644969.2, ENST00000288602.11, ENST00000496384.7 ) |
Sensitivity | true | CIViC Evidence | detail |