Canertinib

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Information
Drug Name
Canertinib
Description
Entry(CIViC)
2
CIViC
Disease Mutation EL ET ED CS VO TR Pubmed Links
lung non-small cell carcinoma EGFR p.Thr790Met (p.T790M)
( ENST00000275493.7, ENST00000450046.2, ENST00000455089.5 ) EGFR p.Thr790Met (p.T790M)
( ENST00000275493.7, ENST00000450046.2, ENST00000455089.5 ) 		D Predictive Supports Sensitivity/Response Somatic 2 18408761 Detail
lung non-small cell carcinoma EGFR p.Leu858Arg (p.L858R)
( ENST00000275493.7, ENST00000450046.2, ENST00000455089.5 ) EGFR p.Leu858Arg (p.L858R)
( ENST00000275493.7, ENST00000450046.2, ENST00000455089.5 ) 		D Predictive Supports Sensitivity/Response Somatic 18408761 Detail
Annotation
Description Associated Genes Associated Variants Sensitivity Supported Source Links
In an in vitro study using NCI-H1666 cells (wildty... EGFR EGFR p.Thr790Met (p.T790M)
( ENST00000275493.7, ENST00000450046.2, ENST00000455089.5 ) EGFR p.Thr790Met (p.T790M)
( ENST00000275493.7, ENST00000450046.2, ENST00000455089.5 ) 		Sensitivity true CIViC Evidence detail
In an in vitro study using NCI-H1666 cells (wildty... EGFR EGFR p.Leu858Arg (p.L858R)
( ENST00000275493.7, ENST00000450046.2, ENST00000455089.5 ) EGFR p.Leu858Arg (p.L858R)
( ENST00000275493.7, ENST00000450046.2, ENST00000455089.5 ) 		Sensitivity true CIViC Evidence detail