AZD5438
Information
- Drug Name
- AZD5438
- Description
- Entry(CIViC)
- 1
CIViC
| Disease | Mutation | EL | ET | ED | CS | VO | TR | Pubmed | Links |
|---|---|---|---|---|---|---|---|---|---|
| cancer | KRAS MUTATION KRAS MUTATION | D |
Predictive
|
Supports
|
Sensitivity/Response | Somatic | 3 | 26881434 | Detail |
Annotation
| Description | Associated Genes | Associated Variants | Sensitivity | Supported | Source | Links |
|---|---|---|---|---|---|---|
| CDK1 was identified in a preclinical siRNA screen ... | KRAS | KRAS MUTATION KRAS MUTATION | Sensitivity | true | CIViC Evidence | detail |
| NCT ID | Status | Phase | Summary | Start date | Completion date |
|---|---|---|---|---|---|
| NCT00088790 | Completed | Phase 1 | AZD5438 in Patients With Advanced Solid Malignancies | July 2004 | December 2005 |
- Target (Drug list of Screening Committee of Anticancer Drugs)
- Cyclin dependent kinase (CDK)