AZ628

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Information
Drug Name
AZ628
Description
Entry(CIViC)
1
CIViC
Disease Mutation EL ET ED CS VO TR Pubmed Links
skin melanoma NF1 MUTATION NF1 MUTATION D Predictive Supports Sensitivity/Response Somatic 2 23288408 Detail
Annotation
Description Associated Genes Associated Variants Sensitivity Supported Source Links
NF1 was identified in an unbiased RNAi screen as m... NF1 NF1 MUTATION NF1 MUTATION Sensitivity true CIViC Evidence detail
AZ628: RAF selective inhibitor BRAF BRAF V600E Sensitivity true MMMP detail
AZ628: RAF selective inhibitor RAF1 RAF1 EXPRESSION Resitance or Non-Reponse true MMMP detail
AZ628 is a BRAF inhibitor BRAF BRAF V600E Sensitivity true MMMP detail