Prosthetic joint infection

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Information
Disease name
Prosthetic joint infection
Disease ID
Description
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
Genes Mutation Description Source Links
NCT ID Status Phase Summary Start date Completion date
NCT03806166 Active, not recruiting N/A Short or Long Antibiotic Regimes in Orthopaedics February 21, 2019 August 7, 2024
NCT01373099 Completed N/A Study of Antibiotic Spacer Design to Treat Infection After Hip Replacement August 2011 August 2020
NCT01373112 Completed N/A Articulating Versus Static Antibiotic Loaded Spacers for the Treatment of Prosthetic Knee Infection December 2011 August 2020
NCT02413034 Completed N/A The Influence of Antibiotic Prophylaxis on Intraoperative Prosthetic Joint Infection Cultures November 2013 January 2015
NCT03426761 Completed Phase 4 Dalbavancin For The Treatment of Gram Positive Osteoarticular Infections January 25, 2018 December 31, 2022
NCT02806063 Completed N/A Bacteriological Setting Before Prosthesis Implantation With One Stage Surgery in Prosthetic Joint Infection April 2016 June 2018
NCT03378427 Completed N/A Tedizolid Prolonged Treatment for Prosthetic Joint Infections August 28, 2018 August 22, 2021
NCT00829556 Completed N/A Efficacy of InteguSeal for Surgical Skin Preparation in Patients Undergoing Total Joint Replacement April 2008 September 2009
NCT03473392 Completed One-stage Exchange Arthroplasty for Chronic Prosthetic Joint Infections April 2016 January 2018
NCT03612076 Completed Cost Of Failure Following Reimplantation After a 2-Stage Exchange Strategy For Hip Or Knee Prosthetic Joint Infection December 1, 2016 July 1, 2018
NCT03694925 Completed Diagnostic Utility of a Novel Point-of-Care Test of Calprotectin for Revision Total Knee Arthroplasty October 29, 2018 March 4, 2020
NCT03717090 Completed Rapid Diagnosis of Prosthetic Joint Infection by Matrix-assisted Laser Desorption December 1, 2016 May 31, 2019
NCT03721328 Completed Phase 2 Safety and Efficacy in Patients Treated for Hip or Knee PJI With Vancomycin and Tobramycin Joint Irrigation October 26, 2018 August 25, 2020
NCT03848091 Completed Prosthesis Infection and One-step Exchange: Pretreatment by Targeted Antibiotic Therapy in At-risk Patients April 1, 2016 January 1, 2018
NCT04042233 Completed Phase 4 Intraosseous Vancomycin in Primary Total Hip Arthroplasty - Designing a Protocol December 31, 2019 September 1, 2022
NCT04067843 Completed N/A Effect of Photodynamic Treatment on Skin Microbiome. Single Center Study September 26, 2019 September 1, 2021
NCT04294862 Completed Phase 1 Tissue Distribution, Pharmacokinetics, Safety, and Tolerability After a Single Dose of TNP-2092 in Participants Undergoing Primary Total Hip or Knee Arthroplasty March 1, 2021 June 29, 2022
NCT04409392 Completed Staphylococcus Lugdunensis Prosthetic Joint Infection February 1, 2021 April 1, 2021
NCT04618276 Completed N/A Effect of Photodynamic Therapy on Skin Microbiome. Single Center Study (PHOMIC-II) January 15, 2021 June 24, 2021
NCT04662632 Completed Phase 2 Abbreviated Protocol for Two-Stage Exchange November 1, 2021 December 22, 2023
NCT04763759 Completed Phase 1 Study to Evaluate Safety and Activity of TRL1068 in Prosthetic Joint Infections February 8, 2021 March 13, 2024
NCT04746001 Enrolling by invitation Artificial Intelligence in the Diagnosis of Orthopaedic Conditions, Particularly Bone Tumours and Infection June 28, 2021 July 1, 2024
NCT05247281 Enrolling by invitation N/A NGS vs Culture Outcomes for Treatment of PJI September 21, 2022 May 2025
NCT02801253 Recruiting Cohort of Prosthetic Joint Infections September 11, 2015 September 2029
NCT05169229 Recruiting Phase 2/Phase 3 Antibiotic Impregnated Bone Graft to Reduce Infection in Hip Replacement. April 1, 2022 December 2031
NCT04650607 Recruiting Phage Safety Cohort Study May 9, 2022 May 9, 2028
NCT05676801 Recruiting Early Phase 1 Effect of Photodynamic Therapy on Skin Microbiome. Single Center Study (PHOMIC-III) February 4, 2023 December 31, 2023
NCT04724603 Recruiting Phage Safety Retrospective Cohort Study February 1, 2021 September 1, 2026
NCT02805803 Recruiting N/A Quality of Life Assessment in Patients Undergoing Prolonged Suppressive Antibiotherapy for Prosthetic Joint Infection. November 9, 2016 June 30, 2025
NCT04762706 Recruiting N/A Measuring Distress in Prosthetic Joint Infection Using a Standardized Metric: CRUTCH Pathway Pilot. March 4, 2021 May 2024
NCT03307109 Recruiting Quality of Life in Patients Having a Prosthetic Joint Infection October 17, 2017 October 2028
NCT06062251 Recruiting Assessing the Performance of Shotgun Metagenomics in the Diagnosis of Complex Prosthetic Joint Infections February 27, 2024 June 2026
NCT04858217 Recruiting Periprosthetic Joint Infections: Diagnostic Accuracy and Cost-effectiveness Analysis of Serum and Synovial Markers February 1, 2022 May 31, 2025
NCT04938193 Recruiting Phase 2 68Ga-citrate PET/CT for the Diagnosis of Chronic Prosthetic Hip or Knee Infection February 2, 2022 February 2025
NCT05000723 Recruiting Long Term Follow-up of Patients With Prosthetic Joint Infection of the Hip Treated at University Hospitals Leuven July 14, 2022 December 2099
NCT05060952 Recruiting Calprotectin in Chronic Prosthetic Joint Infection March 1, 2019 December 31, 2025
NCT05211011 Unknown status Phase 4 Efficacy and Safety of Intravenous Fosfomycin in Prosthetic Joint Infection January 23, 2018 April 30, 2023
NCT03784807 Unknown status New Strategies for Biofilm Related Infections November 2, 2018 November 30, 2020
NCT03826108 Unknown status ARTHR-IS (Arthroplasties' Infections Due to Staphylococcus Aureus) April 16, 2019 December 31, 2020
NCT03200470 Unknown status The Utility of Next-generation Sequencing for the Diagnosis of Periprosthetic Joint Infection February 16, 2017 March 2018
NCT03260010 Unknown status Phase 4 Efficacy and Safety of Intravenous Fosfomycin in Prosthetic Joint Infection January 15, 2018 April 15, 2021
NCT03263832 Unknown status Evaluation of the Antibiofilmogramme Test During Orthopaedic Device-Related Infection June 1, 2015 December 1, 2021
NCT05239312 Unknown status Antibiogram and Biofilm Formation of Bacteria Causing Prosthetic Joint Infections Isolated From Assiut University Hospital March 2022 May 2024
NCT04056780 Unknown status Integrated Microfluidic Systems for Diagnosis of Periprosthetic Joint Infection April 1, 2020 May 31, 2022
NCT04390607 Unknown status Leukocyte Esterase Sensor Test November 1, 2020 October 31, 2021
NCT04946500 Unknown status Clindamycin in Prosthetic Joint Infections Caused by Staphylococcus (CISTA) May 15, 2021 October 15, 2021
NCT04661345 Unknown status Identification of Molecular Marker of Coagulase-negative Staphylococci for the Diagnosis of Prosthetic Joint Infections October 14, 2020 October 14, 2023
NCT03714165 Unknown status Alpha Defensin and 16S rRNA Gene in Diagnosis of PJI January 1, 2019 January 1, 2020
NCT04488458 Unknown status N/A Susceptibility Testing of Biofilm to Guide Treatment of Periprosthetic Joint Infections August 15, 2021 December 31, 2023
NCT04620395 Unknown status N/A Percutaneous Punch Biopsy for Diagnosis of Septic and Aseptic Prosthetic Joint Failure August 20, 2020 June 30, 2022
NCT05269121 Withdrawn Phase 1/Phase 2 Bacteriophage Therapy in First Time Chronic Prosthetic Joint Infections September 2022 November 2024
NCT04787250 Withdrawn Phase 1/Phase 2 Bacteriophage Therapy in Patients With Prosthetic Joint Infections October 2022 May 2024
NCT05269134 Withdrawn Phase 2 Bacteriophage Therapy in Patients With Prosthetic Joint Infections (PJI) March 27, 2023 July 2027