Heartburn
Information
- Disease name
- Heartburn
- Disease ID
- Description
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
| Genes | Mutation | Description | Source | Links |
|---|
| NCT ID | Status | Phase | Summary | Start date | Completion date |
|---|---|---|---|---|---|
| NCT03867591 | Completed | N/A | Fermented Soy and Heartburn Symptom Relief | March 22, 2019 | December 31, 2019 |
| NCT00206024 | Completed | Phase 4 | Acid-Associated Heartburn Symptoms and Dose of Esomeprazole | November 2004 | July 2005 |
| NCT00216489 | Completed | Phase 4 | A Study of the Safety of Rabeprazole Administered to Adults With Gastroesophageal Reflux Disease (GERD) | March 2003 | November 2005 |
| NCT00236184 | Completed | Phase 3 | E3810-A001-313: Efficacy and Safety of 10 mg Rabeprazole for Treating Heartburn in Frequent Sufferers | October 2005 | June 2008 |
| NCT00236197 | Completed | Phase 3 | E3810-A001-312: Efficacy and Safety of 10 mg Rabeprazole for Treating Heartburn in Frequent Sufferers | October 2005 | June 2008 |
| NCT00236392 | Completed | Phase 3 | A Study of Efficacy and Safety of "On-demand" Maintenance Therapy With Rabeprazole in Patients With Non-erosive Reflux Disease (NERD) | October 2001 | October 2002 |
| NCT00243724 | Completed | Phase 3 | HEARD (Long Term) Study - Histology of the Esophagus in Acid-Related Disease | April 2005 | June 2007 |
| NCT00373334 | Completed | Phase 3 | Safety and Efficacy Study of Axid Use in Infants Suffering From Gastroesophageal Reflux Disease (GERD) | August 2006 | February 2008 |
| NCT00382577 | Completed | Phase 3 | Efficacy and Safety of Itopride vs Placebo in Heartburn | October 2006 | December 2006 |
| NCT00389948 | Completed | Phase 3 | Efficacy/Safety of Lansoprazole in Patients With Frequent Heartburn | June 2006 | January 2007 |
| NCT00390390 | Completed | Phase 3 | Efficacy/Safety of Lansoprazole in Patients With Frequent Heartburn | June 2006 | January 2007 |
| NCT01915173 | Completed | N/A | Response to Supplement and Placebo in GERD | June 2013 | April 2014 |
| NCT01928888 | Completed | Phase 4 | Placebo Controlled Phase IV Study to Compare the Efficacy and Safety of a Single Dose of Oral Talcid, a Single Dose of Oral Famotidine and a Single Dose of Placebo in Patients With Acute Heartburn Episodes | May 2003 | February 2004 |
| NCT02096458 | Completed | Phase 1 | Sensory Evaluation of Dexlansoprazole Delayed-Release Orally Disintegrating Tablets | February 2014 | February 2014 |
| NCT02146053 | Completed | Early Phase 1 | Questionnaire to Assess Gastrointestinal Symptoms of Oral Iron. | March 2004 | December 2004 |
| NCT02623816 | Completed | Phase 4 | Symptom Control Satisfaction With Proton Pump Inhibitor Regimen | August 2014 | December 2015 |
| NCT02708355 | Completed | Phase 4 | Pilot Study To Investigate The Association Between Acid Control And Heartburn Symptoms After Proton Pump Inhibitor Treatment | January 2016 | April 2016 |
| NCT02873689 | Completed | Phase 3 | Efficacy and Safety of Dexlansoprazole on Heartburn Relief in Chinese Patients | December 27, 2016 | April 19, 2018 |
| NCT03531372 | Completed | N/A | Mipolixin® Compared to Poliprotect® in Moderate Functional Dyspepsia and Heartburn. | April 24, 2018 | April 30, 2021 |
| NCT00171457 | Completed | Phase 3 | The Effects of Tegaserod on Mechanical Sensitivity of the Esophagus and Stomach in Patients With Heartburn and Dyspepsia. | April 2005 | September 2006 |
| NCT04153552 | Completed | N/A | Upset Stomach Relief for Mild and Moderate Indigestion and Heartburn | October 16, 2019 | August 18, 2020 |
| NCT04560595 | Completed | N/A | Remote Guided Caffeine Reduction | September 10, 2020 | October 1, 2023 |
| NCT04799158 | Completed | Phase 2 | A Study to Evaluate the Efficacy and Safety of Vonoprazan Compared to Placebo in Participants With Symptomatic Non-Erosive Gastroesophageal Reflux Disease | March 25, 2021 | January 17, 2022 |
| NCT05131802 | Completed | Bile Reflux Gastropathy: Prevalence and Risk Factors After Therapeutic Biliary Interventions | January 1, 2018 | December 15, 2020 | |
| NCT05195528 | Completed | Phase 3 | A Study to Evaluate the Efficacy and Safety of Vonoprazan Compared to Placebo for Relief of Heartburn in Participants With Symptomatic Non-Erosive Gastroesophageal Reflux Disease (NERD) | January 17, 2022 | May 17, 2023 |
| NCT05247333 | Completed | N/A | Implementation of a Minor Ailment Service in Community Pharmacy Practice | October 1, 2020 | September 30, 2023 |
| NCT05363618 | Completed | N/A | Tolerability Study of Panosyl-Isomaltooligosaccharides (PIMO) and a Placebo in Subjects With Heartburn | February 10, 2022 | May 30, 2023 |
| NCT00472550 | Completed | Phase 4 | Esomeprazole and Gastric Emptying of Beer | January 2006 | November 2006 |
| NCT00481949 | Completed | Assessment of Gastro-esophageal Reflux Using Endo-Flip vs Bravo | September 2010 | May 2011 | |
| NCT00524329 | Completed | Esomeprazole And Symptomatic Response In Patients With Or Without An Elevated Risk For Non-Steroidal Anti-Inflammatory Drug (NSAID)-Associated GI Damage | January 2006 | October 2007 | |
| NCT00553449 | Completed | Phase 3 | Open Label Study Evaluating Different Dosing Regimens of Rabeprazole in Gastro-esophageal Reflux Disease (GERD) Patients With Night-time Heartburn Symptoms. | July 2004 | September 2005 |
| NCT00579410 | Completed | Comparison of Acid Reflux at Two Levels in the Esophagus Using the BRAVO Capsule | May 2004 | October 2009 | |
| NCT00588939 | Completed | Confocal Laser Microscopy in Non Erosive Reflux Disease | November 2008 | December 2012 | |
| NCT00625274 | Completed | Phase 4 | A Randomized, Open-Label, Comparative 3-Way Treatment Crossover Study of 24-Hour Intragastric pH Profile of Once Daily Oral Administration of Esomeprazole 40mg, Lansoprazole 30mg, and Pantoprazole 40mg at Steady State in NSAID-Using Patients | June 2004 | November 2004 |
| NCT00637845 | Completed | Phase 4 | Study Comparing Esomeprazole Magnesium 40mg Once Daily Versus Lansoprazole 30 mg Twice Daily in Symptom Control of Subjects With Persistent Gastrooesophageal Reflux Disease (GERD) | June 2002 | February 2003 |
| NCT00703534 | Completed | Phase 2 | Validation of Patient-reported Outcomes Measures for the Assessment of Gastroesophageal Reflux Disease (GERD) Symptoms | May 2008 | January 2009 |
| NCT00842387 | Completed | Evaluation Study of a Management Strategy for Gastroesophageal Reflux Disease (GERD) | January 2009 | December 2009 | |
| NCT00944671 | Completed | Phase 1 | A Study to Assess the Bioequivalence of Famotidine/Antacid Combination Tablets Compared to Famotidine/Antacid EZ Chew Tablets (0208C-145)(COMPLETED) | February 2008 | March 2008 |
| NCT00945750 | Completed | Phase 1 | A Study to Assess the Bioequivalence of Famotidine Chewable Tablets and Film-Coated Tablets (0208-144) | August 2006 | September 2006 |
| NCT01005251 | Completed | Phase 2 | Investigate the Effect of Different Doses of Lesogaberan (AZD3355) as add-on to PPI in GERD Patients With Partial Response to PPI | October 2009 | July 2010 |
| NCT01037452 | Completed | Phase 2 | Proof of Concept Study Efficacy of an Antacid/Lansoprazole Combination for Relief of Heartburn | December 2009 | |
| NCT01095133 | Completed | Phase 1 | Do Acid Sensing Ion Channels Contribute to Heartburn? | March 2010 | September 2011 |
| NCT01149395 | Completed | Phase 1 | Can E-cadherin Found in Tissue/Blood be Valuable in Identifying & Monitoring Patients With Post-proton Pump Inhibitor (PPI)-Responsive Heartburn | June 2010 | April 2012 |
| NCT01249651 | Completed | Phase 4 | To Assess the Efficacy of Esomeprazole 40 mg Once Daily in Subjects Who Still Had Heartburn After Receiving Rabeprazole | November 2010 | June 2011 |
| NCT01337804 | Completed | Phase 1 | A Study to Compare Omeprazole Administered as Zegerid® Powder and as Prilosec® Capsule in Healthy Participants (P08050)(CL2010-12) | January 2011 | January 2011 |
| NCT01338077 | Completed | Phase 3 | Efficacy and Safety of Sodium Alginate Oral Suspension to Treat Non-erosive Gastro-esophageal Reflux Disease | October 2010 | January 2012 |
| NCT01370525 | Completed | Phase 3 | Efficacy of Esomeprazole in Patients With Frequent Heartburn | August 2011 | October 2011 |
| NCT01370538 | Completed | Phase 3 | Efficacy of Esomeprazole in Patients With Frequent Heartburn | August 2011 | October 2011 |
| NCT01587885 | Completed | Phase 4 | Comparison of Two Omeprazole-Containing Products for Relief of Frequent Heartburn (MK-0764A-036) | January 2012 | May 2012 |
| NCT06098742 | Not yet recruiting | N/A | Comparative Pharmacodynamics and Pharmacodynamics Equivalence of Antareit 800 mg/10 ml Oral Suspension and Riopan 800 mg Chewable Tablets in Healthy Volunteers | May 31, 2024 | September 20, 2025 |
| NCT05901740 | Not yet recruiting | Prevalence of Fuctional Heartburn in Patients With IBS . | July 1, 2023 | August 1, 2024 | |
| NCT05976165 | Recruiting | N/A | A Study of Breath Testing for Small Intestinal Bacterial Overgrowth | November 17, 2023 | December 31, 2024 |
| NCT06075082 | Recruiting | N/A | The Effect of the LEFT Smartwatch App as Sleep Positional Therapy for Nocturnal Gastroesophageal Reflux Symptoms. | October 1, 2023 | September 1, 2025 |
| NCT06094062 | Recruiting | N/A | Smartphone App-assisted PPI | September 5, 2023 | December 15, 2024 |
| NCT06293326 | Recruiting | Phase 1 | A First-in-Human Study to Learn How Well a Bi-Layer Calcium Carbonate Antacid Tablet Works Compared to a Standard, Non-Layered Calcium Carbonate Tablet in Healthy Male Participants | March 6, 2024 | June 6, 2024 |
| NCT06391177 | Recruiting | Phase 1 | A Study to Evaluate Vonoprazan Concentrations in Breast Milk of Healthy Lactating Women Receiving Vonoprazan 20 mg Once Daily | June 3, 2024 | August 2024 |
| NCT05629143 | Recruiting | Phase 4 | Primary carE PPi dEprescRibing Trial | May 12, 2023 | September 1, 2025 |
| NCT01696734 | Recruiting | Phase 3 | Domperidone in Treating Patients With Gastrointestinal Disorders | October 23, 2012 | October 31, 2025 |
| NCT01199679 | Terminated | N/A | Rubber Band Ligation and Mucosectomy for Gastroesophageal Reflux Disease (GERD) | June 2011 | March 2013 |
| NCT00536328 | Terminated | What is the Predictive Value of the Reflux Impact Scale | October 2007 | June 2008 | |
| NCT01129713 | Unknown status | Phase 1/Phase 2 | Comparison of Nexium Versus Secretol in the Healing and Controlling of Symptoms in GERD Patients With Severe EE. | May 2010 | May 2015 |
| NCT00471796 | Unknown status | N/A | A Comparison of Factors of Symptoms Generation and Evaluation of Role of Biofeedback in Patients With Different Types of Functional Esophageal Disorders (Functional Heartburn and Functional Chest Pain) | ||
| NCT02277886 | Unknown status | Phase 4 | Esomeprazole Plus Alginate vs. Esomeprazole Alone for Treatment of Nighttime Reflux Symptom and Sleep Disturbances | November 2014 | June 2016 |
| NCT04252144 | Unknown status | N/A | Study of Dietary Patterns and Food Diversity in Russian GERD Patients | January 30, 2020 | December 31, 2023 |
| NCT02105090 | Unknown status | Phase 4 | Efficacy Study of Articaine Lozenge to Enhance the Procedural Compliance of the Adults Undergoing Gastroduodenoscopy | October 2014 | September 2020 |
- ICD10 preferred id (Insert disease from ICD10)
- D0014984
- ICD10 class code (Insert disease from ICD10)
- R12
- MeSH unique ID (MeSH (Medical Subject Headings))
- D006356