Cardiotoxicity
Information
- Disease name
- Cardiotoxicity
- Disease ID
- Description
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
| Genes | Mutation | Description | Source | Links |
|---|
| NCT ID | Status | Phase | Summary | Start date | Completion date |
|---|---|---|---|---|---|
| NCT04737265 | Active, not recruiting | Phase 1/Phase 2 | Pilot Study of an NTproBNP Guided Strategy of Cardioprotection | March 18, 2021 | May 2025 |
| NCT04598646 | Active, not recruiting | N/A | The Harmonized Interventions to Maintain Health Via Appropriate Risk Factor Modification and Lifestyle Changes in Pediatric, Adolescent and Young Adult Cancer Survivors Pilot Study | April 1, 2022 | December 2027 |
| NCT04486573 | Active, not recruiting | N/A | Cardiac Effects From Radiation Therapy by MRI | July 15, 2020 | March 2025 |
| NCT04361240 | Active, not recruiting | Cardiotoxicity in Breast Cancer Patients Treated With Proton or Photon Radiotherapy: A RadComp Companion Study | August 1, 2020 | April 2025 | |
| NCT02942615 | Active, not recruiting | N/A | The Safety Management of Cardiac Toxicity in Breast Cancer Patients Under Multidiscipline Therapy. | June 27, 2017 | October 2025 |
| NCT05728632 | Active, not recruiting | Phase 3 | Cardioprotective Effects of Nebivolol Versus Placebo in Patients Undergoing Chemotherapy With Anthracyclines | January 1, 2019 | February 28, 2023 |
| NCT03862131 | Active, not recruiting | Phase 2 | PROactive Evaluation of Function to Avoid CardioToxicity | March 13, 2019 | July 7, 2024 |
| NCT05118178 | Active, not recruiting | Atherosclerosis in Chemotherapy-related Cardiotoxicity | November 15, 2021 | August 15, 2024 | |
| NCT04023110 | Active, not recruiting | Phase 1 | Risk-Guided Cardioprotection With Carvedilol in Breast Cancer Patients Treated With Doxorubicin and/or Trastuzumab | August 9, 2019 | December 31, 2024 |
| NCT04036032 | Active, not recruiting | Role of Aerobic Exercise to Modulate Cardiotoxicity in Long Term Cancer Survivors Exposed to Anthracycline Therapy | June 19, 2015 | September 27, 2025 | |
| NCT01724450 | Completed | Phase 3 | Carvedilol Effect in Preventing Chemotherapy - Induced Cardiotoxicity | April 2013 | June 2017 |
| NCT00292526 | Completed | Phase 4 | Prevention of Chemotherapy-induced Cardiotoxicity in High-risk Patients | November 2000 | November 2011 |
| NCT03940625 | Completed | N/A | Anthracycline Induced Cardiotoxicity - Early Detection by Combination of Diastolic Strain and T2-mapping | June 3, 2015 | April 30, 2022 |
| NCT04026737 | Completed | Cardiovascular Effects of CART Cell Therapy | July 22, 2019 | November 16, 2022 | |
| NCT02086695 | Completed | Early Detection of Broken Hearts in Cancer Patients | June 2013 | September 2015 | |
| NCT03964142 | Completed | N/A | Exercise-based Cardiac Rehabilitation for the Prevention of Breast Cancer Chemotherapy-induced Cardiotoxicity | August 1, 2018 | January 1, 2023 |
| NCT05676606 | Completed | N/A | Cardiotoxicity Monitoring With Single-lead Electrocardiogram | December 10, 2020 | May 25, 2023 |
| NCT03166813 | Completed | N/A | Remote Ischaemic Preconditioning in Childhood Cancer | July 1, 2017 | June 1, 2022 |
| NCT02798679 | Completed | Cardiac Fibrosis and Risk Prediction in Cancer Treatment-Related Cardiotoxicity | August 2016 | September 1, 2022 | |
| NCT03235427 | Completed | The CAROLE (CArdiac Related Oncologic Late Effects) Study | June 27, 2017 | June 26, 2018 | |
| NCT03389724 | Completed | Phase 3 | Prevention of Chemotherapy Induced Cardiotoxicity in Children With Bone Tumors and Acute Myeloid Leukemia | November 14, 2017 | November 1, 2021 |
| NCT00543062 | Completed | Phase 1 | Staccato Prochlorperazine Thorough QT/QTc | October 2007 | December 2007 |
| NCT01014065 | Completed | A Prospective Study of Acute Cardiovascular Effects of First-line Sunitinib in Metastatic Renal Cell Carcinoma Patients (SUnitinib Prospective CardiovasculaR Effect) | July 2011 | January 2013 | |
| NCT03543228 | Completed | MyoStrain CMR for the Detection of Cardiotoxicity | August 1, 2017 | January 31, 2020 | |
| NCT02909712 | Completed | Phase 2 | Cardiac Safety of Dihydroartemisinin-Piperaquine Amongst Pregnant Women in Tanzania | September 2016 | February 2020 |
| NCT01246778 | Completed | Sunitinib and Atrial Trabeculae Contractility | November 2010 | April 2014 | |
| NCT01665300 | Completed | Usefulness of Myocardial Deformation Imaging for Trastuzumab-induced Cardiotoxicity | July 2011 | April 2014 | |
| NCT03760237 | Completed | Cardiovascular Function in Acute Leukemia | December 10, 2018 | May 6, 2024 | |
| NCT05130489 | Completed | CAR T Cell Therapy Related Cardiovascular Outcomes | January 18, 2021 | May 1, 2023 | |
| NCT04896242 | Completed | Multimodal Assesment of Acute Cardiac Toxicity Induced by Thoracic Radiotherapy in Cancer Patients | January 9, 2020 | April 1, 2024 | |
| NCT06211413 | Enrolling by invitation | Hypertension and Arrhythmias in CLL Patients Treated With BTK Inhibitors | February 7, 2024 | August 2025 | |
| NCT04305613 | Enrolling by invitation | Cardiotoxicity in Locally Advanced Lung Cancer Patients Treated With Chemoradiation Therapy | September 14, 2020 | December 2028 | |
| NCT05377320 | Not yet recruiting | PAtient Similarity for Decision-Making in Prevention of Cardiovascular Toxicity (PACT): A Feasibility Study | June 2024 | December 2026 | |
| NCT05465031 | Not yet recruiting | Phase 4 | Sacubitril/Valsartan in PriMAry preventIoN of the Cardiotoxicity of Systematic breaST canceR trEAtMent (MAINSTREAM) | February 2023 | February 2028 |
| NCT06005259 | Not yet recruiting | Phase 4 | Effect of Spironolactone in the Prevention of Anthracycline-induced Cardiotoxicity (SPIROTOX) | October 1, 2023 | December 1, 2025 |
| NCT06332131 | Not yet recruiting | Effects of Immune Checkpoint Inhibitors on Coronary Microvasculature | May 2024 | April 2027 | |
| NCT06340516 | Recruiting | N/A | NT-proBNP to Assess Trastuzumab-induced Cardiotoxicity | March 14, 2024 | March 14, 2029 |
| NCT03418961 | Recruiting | Phase 3 | S1501 Carvedilol in Preventing Cardiac Toxicity in Patients With Metastatic HER-2-Positive Breast Cancer | November 1, 2017 | January 1, 2030 |
| NCT03486340 | Recruiting | N/A | Prevention of Chest Pain in Chemo-treated Cancer Patients | April 11, 2018 | June 30, 2025 |
| NCT03711110 | Recruiting | N/A | Cardiovascular Prevention Strategies in Elderly Patients With Cancer (CARTIER Clinical Trial) | August 2, 2019 | November 30, 2025 |
| NCT03748550 | Recruiting | N/A | Exercise to Prevent AnthraCycline-based Cardio-Toxicity Study 2.0 (EXACT2) | April 29, 2019 | December 31, 2023 |
| NCT04262830 | Recruiting | Cancer Therapy Effects on the Heart | September 30, 2019 | September 30, 2029 | |
| NCT04827563 | Recruiting | Dyspnea and Cardiotoxicity in Multiple Myeloma Patients Who Receive Carfilzomib | March 22, 2021 | August 1, 2026 | |
| NCT04880317 | Recruiting | N/A | Validation of Quantitative Myocardial Tissue Characterization Through Non-gated CT | May 7, 2021 | December 2024 |
| NCT05023785 | Recruiting | N/A | The HIMALAYAS Trial and Lifestyle Changes in Pediatric, Adolescent and Young Adult Cancer Survivors Study: A Multicentre Randomized Controlled Trial | January 1, 2024 | March 2027 |
| NCT05036252 | Recruiting | Study of Cardiopulmonary Exercise Testing in Women Who Have HER2-Positive Breast Cancer With Mild Cardiotoxicity | August 27, 2021 | August 27, 2024 | |
| NCT05078190 | Recruiting | Mechanisms, Predictors, and Social Determinants of Cardiotoxicity in Breast Cancer | October 21, 2021 | October 2039 | |
| NCT05096338 | Recruiting | Mechanisms, Predictors, and Social Determinants of Cardiotoxicity in Prostate Cancer | October 27, 2021 | October 2028 | |
| NCT05159479 | Recruiting | Defining Robust Predictors of Chemotherapy Related Cardiotoxicity | October 13, 2021 | July 1, 2024 | |
| NCT05271162 | Recruiting | Phase 3 | Empagliflozin in the Prevention of Cardiotoxicity in Cancer Patients Undergoing Chemotherapy Based on Anthracyclines | September 30, 2023 | February 1, 2028 |
| NCT05406635 | Recruiting | N/A | Imaging Versus Cardiac Biomarker Monitored HER2 Directed Therapy in Patients With Breast Cancer | October 1, 2021 | September 1, 2025 |
| NCT05507879 | Recruiting | TRPC6 Characterization to Predict and Prevent Chemotherapy Related Cardiomyopathy and Heart Failure With Breast Cancer | August 18, 2022 | September 1, 2027 | |
| NCT05508087 | Recruiting | Cardiovascular Diagnostic in Assessment of Risk HDS and HCT in Patients With Haemoblasts. | July 17, 2019 | December 1, 2024 | |
| NCT05598879 | Recruiting | Global Cardio Oncology Registry | July 1, 2022 | July 1, 2027 | |
| NCT05699915 | Recruiting | N/A | Extensive CArdioVAscular Characterization and Follow-up of Patients Receiving Immune Checkpoint Inhibitors | January 7, 2022 | November 30, 2026 |
| NCT05703126 | Recruiting | N/A | Clinical and Diagnostic Significance of Endothelial Dysfunction and Myocardial Contractility in Patients With AML | December 1, 2022 | August 3, 2025 |
| NCT05732051 | Recruiting | Phase 2 | Nicotinamide Riboside and Prevention of Cancer Therapy Related Cardiac Dysfunction in Breast Cancer Patients | March 16, 2023 | September 30, 2035 |
| NCT05746598 | Recruiting | Effect of Genetic and Epigenetic Factors on the Clinical Response and Toxicity to Cisplatin Among Egyptian Non-small Cell Lung Cancer Patients | July 1, 2020 | April 1, 2023 | |
| NCT05781672 | Recruiting | N/A | Prediction of Delayed Toxic Cardiomyopathy in Children | March 16, 2023 | September 30, 2025 |
| NCT05786014 | Recruiting | N/A | The Effects of Two Exercise Interventions on Breast Cancer Patients Undergoing Cardiotoxic Chemotherapies | April 1, 2023 | March 15, 2025 |
| NCT05851053 | Recruiting | Breast Cancer Long-term Outcomes on Cardiac Functioning: a Longitudinal Study | September 1, 2022 | December 31, 2026 | |
| NCT05880160 | Recruiting | N/A | Safety of Withdrawal of Pharmacological Treatment for Recovered HER2 Targeted Therapy Related Cardiac Dysfunction | July 14, 2023 | September 2025 |
| NCT05892146 | Recruiting | N/A | Strategy Therapy on Cancer Therapy-Related Cardiac Dysfunction | May 5, 2021 | December 31, 2025 |
| NCT05921279 | Recruiting | Understanding CARdiac Events in Breast Cancer | January 14, 2023 | July 2026 | |
| NCT05992337 | Recruiting | New Biomarkers in the Prediction of Chemotherapy-induced Cardiotoxicity. | September 1, 2021 | January 2025 | |
| NCT06023576 | Recruiting | Phase 2 | A Study of Blood Pressure Control During Cancer Treatment | August 18, 2023 | May 30, 2028 |
| NCT06048458 | Recruiting | Cancer Treatment Related Cardiovascular Toxicity: Comprehensive Myocardial and Vascular Phenotyping | May 18, 2022 | February 2024 | |
| NCT06060132 | Recruiting | Risk Analysis of Cardiotoxic Medication Use Due to Sodium Arsenite Chloride Injection | January 29, 2023 | December 31, 2023 | |
| NCT06183437 | Recruiting | Phase 4 | The STOP-MED CTRCD Trial | March 4, 2024 | December 2031 |
| NCT06270667 | Recruiting | N/A | Effects of Exercise Training in Survivors of Lymphoma | March 20, 2024 | September 1, 2028 |
| NCT04476576 | Recruiting | N/A | Aerobic Exercise is Cardio-protective in Hemato-oncological Disease and New-onset Chemotherapy | March 2, 2021 | March 2024 |
| NCT04568161 | Recruiting | N/A | Effect of Anthracyclines and Cyclophosphamide on Cardiovascular Responses | August 3, 2020 | March 3, 2025 |
| NCT04790266 | Recruiting | Early Detection of Cardiotoxicity From Systemic and Radiation Therapy in Breast Cancer Patients | September 15, 2020 | December 31, 2024 | |
| NCT04822077 | Recruiting | N/A | Study on Proton Radiotherapy of Thymic Malignancies | April 18, 2018 | April 1, 2029 |
| NCT03038997 | Terminated | Early Detection of Cardiac Toxicity in Childhood Cancer Survivors | November 2014 | March 11, 2018 | |
| NCT03850171 | Terminated | N/A | Cancer Adverse Effects PReventIon With Care & Exercise: the CAPRICE Study | May 1, 2019 | January 31, 2023 |
| NCT02674204 | Terminated | Phase 2 | STOP Heart Disease in Breast Cancer Survivors Trial | May 5, 2016 | May 25, 2018 |
| NCT04461223 | Unknown status | Evaluation of Myocardial Injury After Anthracycline Chemotherapy in Osteosarcoma Patients Using CMR | December 1, 2019 | December 1, 2021 | |
| NCT03155802 | Unknown status | Novel Biomarkers and Echocardiography for Subclinical Cardiac Toxicity in Breast Cancer Patients Receiving Anthracyclines | April 18, 2017 | December 2020 | |
| NCT04055636 | Unknown status | Observational Trial of Cardiotoxicity in Patients Undergoing Chemotherapy. | June 14, 2019 | June 2024 | |
| NCT02471885 | Unknown status | N/A | Effect of Remote Ischaemic Conditioning in Oncology Patients | December 16, 2015 | December 2021 |
| NCT04047901 | Unknown status | N/A | Effect of Physical Training in Patients With Heart Failure Caused by Chemotherapy for Cancer Treatment | November 7, 2016 | February 2021 |
| NCT04632407 | Unknown status | N/A | Can Flaxseed Prevent Broken Hearts in Women With Breast Cancer Study? | October 21, 2020 | December 31, 2022 |
| NCT04046315 | Unknown status | Early Detection of Cardiac Damage With CMR in Women With Breast Cancer | March 1, 2020 | March 31, 2021 | |
| NCT05298072 | Unknown status | Identification of Novel Inflammation-related Biomarkers for Early Detection of Anthracycline-induced Cardiotoxicity in Breast Cancer Patients | April 2022 | December 2023 | |
| NCT05349058 | Unknown status | Assessment of Myocardial Injury in Patients Treated With Immune Checkpoint Inhibitors | January 17, 2021 | December 30, 2023 | |
| NCT03650205 | Unknown status | N/A | Ivabradine to Prevent Anthracycline-induced Cardiotoxicity | January 22, 2019 | December 1, 2021 |
| NCT04877899 | Unknown status | Mazankowski Alberta Heart Institute (MAHI) EchoGo Discovery 1 Protocol | October 8, 2020 | November 30, 2021 | |
| NCT02571894 | Unknown status | N/A | The Cardio-Oncology Breast Cancer Study | July 2014 | February 2020 |
| NCT04885088 | Unknown status | Smart Home Care of Cloud Base ECG on the Cardiotoxicity Prevention on the Cancer Patients. | July 1, 2021 | June 30, 2023 | |
| NCT03981588 | Unknown status | Cardiotoxicity in the Elderly | March 2015 | March 2022 | |
| NCT04939857 | Unknown status | Phase 2/Phase 3 | Effect of Trimetazidine on Radiotherapy-induced Heart Damage. | June 25, 2021 | August 31, 2022 |
| NCT04961307 | Unknown status | Evaluation of Heart Function in Breast Cancer Patients Using Trastuzumab | July 5, 2019 | December 30, 2021 | |
| NCT05019365 | Unknown status | Investigating the Long-term Cardiac Sequelae of Trastuzumab Therapy | March 15, 2021 | November 25, 2022 | |
| NCT03186404 | Unknown status | Phase 2 | Statins for the Primary Prevention of Heart Failure in Patients Receiving Anthracycline Pilot Study | May 10, 2018 | December 2023 |
| NCT05040867 | Unknown status | N/A | Exercise Prescription Guided by Heart Rate Variability in Breast Cancer Patients | September 13, 2021 | September 20, 2022 |
| NCT02236806 | Unknown status | Phase 3 | Cardiotoxicity Prevention in Breast Cancer Patients Treated With Anthracyclines and/or Trastuzumab | July 2015 | June 2022 |
| NCT03930394 | Unknown status | Vascular Cardiotoxicity of Ponatinib | May 15, 2019 | May 1, 2022 | |
| NCT04191265 | Unknown status | Cardiotoxicity of Aluminum Phosphide Poisoning; Tropinin and CKmb as Early Biomarkers | December 5, 2019 | June 5, 2020 | |
| NCT05150080 | Unknown status | Early Identification and Evaluation of Cyclophosphamide Cardiotoxicity | July 10, 2021 | June 1, 2022 | |
| NCT04092309 | Unknown status | N/A | Effect of Angiotensin Converting Enzyme and Sacubitril Valsartan in Patients After Bone Marrow Transplantation | September 20, 2019 | September 1, 2021 |
| NCT04429633 | Unknown status | N/A | Strain vs. Left Ventricular Ejection Fraction-based Cardiotoxicity Prevention in Breast Cancer | July 19, 2019 | July 18, 2023 |
- MeSH unique ID (MeSH (Medical Subject Headings))
- D066126