Acute lymphoid leukemia
Information
- Disease name
- Acute lymphoid leukemia
- Disease ID
- Description
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
| Genes | Mutation | Description | Source | Links |
|---|
| NCT ID | Status | Phase | Summary | Start date | Completion date |
|---|---|---|---|---|---|
| NCT04669210 | Active, not recruiting | Phase 2 | PTCy and Ruxolitinib vs PTCy, Tacrolimus and MMF in MUD and Haploidentical HSCT | November 3, 2020 | February 2025 |
| NCT04013685 | Active, not recruiting | Phase 1 | Precision-T: A Study of Orca-T in Recipients Undergoing Allogeneic Transplantation for Hematologic Malignancies | November 21, 2019 | July 2026 |
| NCT03792633 | Active, not recruiting | Phase 2 | Study of huCART19 for Very High-Risk (VHR) Subsets of Pediatric B-ALL | January 18, 2019 | August 2024 |
| NCT05316701 | Active, not recruiting | Phase 3 | Precision-T: A Randomized Study of Orca-T in Recipients Undergoing Allogeneic Transplantation for Hematologic Malignancies | June 21, 2022 | April 2027 |
| NCT04778579 | Active, not recruiting | Phase 2 | Study of the Infusion of ARI-0001 Cells in Patients With CD19 + Acute Lymphoid Leukemia Resistant or Refractory to Therapy | May 11, 2021 | December 31, 2025 |
| NCT02294552 | Completed | Phase 2 | Post-transplantation Cyclophosphamide as GVHD Prophylaxis After HSCT | October 2014 | November 2017 |
| NCT02953730 | Completed | Phase 4 | The Study on the Pharmacokinetics of PEG-rhG-CSF in Children and Adolescents | September 2015 | |
| NCT02458235 | Completed | Phase 2 | Donor Lymphocyte Infusion With Azacitidine to Prevent Hematologic Malignancy Relapse After Stem Cell Transplantation | June 2, 2015 | March 15, 2019 |
| NCT03833180 | Completed | Phase 1 | A Study of Zilovertamab Vedotin (MK-2140) (VLS-101) in Participants With Hematologic Malignancies (MK-2140-001) | March 14, 2019 | December 18, 2023 |
| NCT02767388 | Completed | Electrophysiological Biomarkers of Chemotherapy-related Cognitive Impairment and Recovery | September 1, 2016 | March 15, 2018 | |
| NCT05166135 | Completed | Latin American Real-world Study in Acute Leukemia | December 10, 2021 | November 15, 2022 | |
| NCT00983138 | Completed | Phase 2 | Efficacy and Safety of Recombinant Asparaginase in Infants With Previously Untreated Acute Lymphoid Leukemia (ALL) | July 2009 | February 2011 |
| NCT01344876 | Completed | Phase 1 | Phase I Study of OPB-51602 in Patients With Hematologic Malignancies | April 2011 | April 2014 |
| NCT01461538 | Completed | Phase 2 | Brentuximab Vedotin in Patients With CD30-positive Nonlymphomatous Malignancies | October 2011 | December 2014 |
| NCT01720264 | Completed | Phase 2 | Multicenter Phase II of CD26 Using Sitagliptin for Engraftment After UBC Transplant | November 2, 2012 | December 15, 2017 |
| NCT00590915 | No longer available | Erwinase Master Treatment Protocol | |||
| NCT06427330 | Not yet recruiting | Phase 2 | Phase II Study of Post-Transplant Low-Dose Inotuzumab Ozogamicin to Prevent Relapse of Acute Lymphoblastic Leukemia | May 20, 2024 | May 20, 2026 |
| NCT05827549 | Not yet recruiting | Phase 2 | Evaluation of Treatment Efficacy According to Risk Group in Relapsed Childhood Acute Lymphoblastic Leukemia | April 1, 2024 | December 31, 2032 |
| NCT05943093 | Not yet recruiting | H19 in Acute Lymphoblastic Leukemia. | July 2023 | August 2025 | |
| NCT03448393 | Recruiting | Phase 1 | CD19/CD22 Chimeric Antigen Receptor (CAR) T Cells in Children and Young Adults With Recurrent or Refractory CD19/CD22-expressing B Cell Malignancies | March 26, 2018 | December 31, 2040 |
| NCT05442515 | Recruiting | Phase 1/Phase 2 | CD19/CD22 Bicistronic Chimeric Antigen Receptor (CAR) T Cells in Children and Young Adults With Recurrent or Refractory CD19/CD22-expressing B Cell Malignancies | December 28, 2022 | July 1, 2029 |
| NCT05535855 | Recruiting | Phase 1 | UCD19 CAR T Therapy in Adults With B-ALL and MRD Positivity in CR1 | January 24, 2024 | July 2027 |
| NCT05792007 | Recruiting | N/A | Study of the Medullary Microenvironment in Acute Childhood Leukemia | October 26, 2023 | October 24, 2028 |
| NCT05959720 | Recruiting | Adult Acute Lymphoblastic Leukemia Treated With Pediatric Regimen in Brazil | September 5, 2023 | June 2030 | |
| NCT04167683 | Recruiting | Muscle Dysfunction in Patients With Hematological Diseases Referred to Stem Cell Transplant | October 1, 2023 | December 31, 2026 | |
| NCT05322850 | Suspended | Phase 1/Phase 2 | Phase I/II Trial: Engineered Donor Graft (Orca Q) for Pediatric Hematopoietic Cell Transplant (HCT) | August 16, 2022 | September 2027 |
| NCT01037764 | Terminated | Phase 2 | Donor-specific Allogeneic Hematopoietic Cell Transplantation for Acute Lymphoblastic Leukemia (ALL) | January 2010 | December 2016 |
| NCT02419755 | Terminated | Phase 2 | Bortezomib and Vorinostat in Younger Patients With Refractory or Relapsed MLL Rearranged Hematologic Malignancies | April 14, 2015 | December 31, 2016 |
| NCT02435550 | Terminated | N/A | iCare for Cancer Patients | June 26, 2015 | October 1, 2019 |
| NCT01749111 | Terminated | Phase 3 | Comparison Between Cyclophosphamide and Combination of Methotrexate + Calcineurin Inhibitor for GVHD Prophylaxis | December 2012 | August 2016 |
| NCT02345915 | Unknown status | N/A | Evaluation of Adverse Long-term Effects in Young Adult Survivors of Acute Leukemia | November 2014 | May 2019 |
| NCT02933333 | Unknown status | Phase 4 | G-CSF Alone or Combination With GM-CSF on Prevention and Treatment of Infection in Children With Malignant Tumor | September 27, 2016 | December 2020 |
| NCT02605460 | Unknown status | Phase 2 | Chemo Sensitization Before Hematopoietic Stem Cell Transplantation in Patients With Acute Leukemia in Complete Remission | February 2014 | November 2021 |
| NCT03977103 | Unknown status | Phase 2 | Irradiation-based Myeloablative Conditioning Followed by Treg/Tcon Immunotherapy in HSCT | February 2014 | February 28, 2023 |
| NCT02413021 | Unknown status | Phase 1 | The Effect of Deferasirox on Response Rate of Acute Leukemia Patients Not Treated by Standard Chemotherapy Regimens | May 2016 | October 2016 |
| NCT05150561 | Unknown status | Muscle Dysfunction in Patients With Haematological Diseases | November 8, 2021 | December 31, 2023 | |
| NCT03610438 | Unknown status | Phase 2 | Feasibility and Effectiveness of Inotuzumab Ozogamicin in B-Cell Acute Lymphoblastic Leukemia | October 30, 2019 | November 2022 |
| NCT03367299 | Unknown status | Phase 2 | Sequential Chemotherapy and Blinatumomab to Improve MRD Response and Survival in Acute Lymphoblastic Leukemia | June 8, 2018 | February 2024 |
| NCT04464889 | Withdrawn | Phase 1 | HA-1H TCR T Cell for Relapsed/Persistent Hematologic Malignancies After Allogeneic Stem Cell Transplantation | July 2, 2020 | July 2025 |