Anhedonia
Information
- Disease name
- Anhedonia
- Disease ID
- Description
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
| Genes | Mutation | Description | Source | Links |
|---|
| NCT ID | Status | Phase | Summary | Start date | Completion date |
|---|---|---|---|---|---|
| NCT02498925 | Active, not recruiting | N/A | Examining Reward-Related Predictors and Mechanisms of Change in BA Treatment for Anhedonic Adolescents | December 2015 | December 2023 |
| NCT03848715 | Active, not recruiting | Phase 1 | Sleep and Healthy Aging Research on Depression for Younger Women | October 2, 2019 | May 2, 2024 |
| NCT01701141 | Completed | Depression and Dopamine Transporter Function Study Using C-11 Altropane | January 2012 | July 2014 | |
| NCT01850472 | Completed | Brain Mechanisms of Emotion and Motivation: A Mind-Body Study | March 2013 | January 2016 | |
| NCT02494050 | Completed | N/A | Telemedicine for Women With Anhedonia in Bipolar and Unipolar Disorder | June 2015 | August 2016 |
| NCT02569034 | Completed | N/A | Dissociating Components of Anhedonia: A Pilot fMRI Study | February 2016 | May 8, 2018 |
| NCT01606904 | Completed | N/A | The Effect of CBT- Based Weight Loss Program on Obesity | May 2012 | March 2016 |
| NCT01659814 | Completed | Dopamine Neurotransmission in Major Depression | March 2011 | December 2012 | |
| NCT02859103 | Completed | Phase 4 | Dimensional Approach to Evaluate Reward Processing in Major Depressive Disorder Pre- and Post-Desvenlafaxine Treatment | June 1, 2017 | November 4, 2019 |
| NCT02874534 | Completed | N/A | Development of a Novel Transdiagnostic Intervention for Anhedonia - R61 Phase | June 22, 2017 | July 31, 2019 |
| NCT02905604 | Completed | N/A | Magnetic Stimulation of the Brain in Schizophrenia or Depression | September 29, 2016 | January 20, 2020 |
| NCT02958228 | Completed | N/A | The Effect of Computerized Cognitive Training on Mood and Thinking Style Amongst Patients in Inpatient Settings | November 2016 | March 2018 |
| NCT03043560 | Completed | Phase 2 | Study to Treat Major Depressive Disorder With a New Medication | September 25, 2017 | August 30, 2019 |
| NCT03369015 | Completed | Phase 1 | Effect of D-amphetamine on Reward Functioning | January 24, 2018 | May 23, 2019 |
| NCT03856177 | Completed | N/A | Translational Model of Anhedonia | April 1, 2019 | July 1, 2021 |
| NCT03939676 | Completed | Evaluating Motivation and Reward Mechanisms and Brain Substrates in Adults With Obesity | October 30, 2019 | December 15, 2020 | |
| NCT04036136 | Completed | N/A | Development of a Novel Transdiagnostic Intervention for Anhedonia - R33 Phase | August 1, 2019 | July 31, 2023 |
| NCT04121091 | Completed | Phase 2 | Pramipexole to Target "Anhedonic Depression" | October 4, 2019 | March 18, 2021 |
| NCT04647019 | Completed | N/A | The Effects of Wild Blueberries on Depressive Symptoms in Young Adults | November 26, 2021 | June 11, 2022 |
| NCT04723147 | Completed | Phase 4 | DTA (Dopaminergic Therapy for Anhedonia) Study | January 29, 2021 | October 11, 2023 |
| NCT04791137 | Completed | N/A | Feasibility Randomized Controlled Trial Using a 'Leapfrog' Design | April 9, 2021 | January 11, 2022 |
| NCT05084924 | Completed | N/A | Investigating the Causal Role of Prefrontal Control in Decision-making in Patients With Anhedonia | November 2, 2021 | July 31, 2023 |
| NCT05165394 | Completed | Phase 2 | Study to Evaluate the Efficacy and Safety of Once-Weekly Oral NBI-1065846 in the Treatment of Anhedonia in MDD | November 30, 2021 | September 7, 2023 |
| NCT05223842 | Completed | N/A | Family Promoting Positive Emotions Pilot Study | December 1, 2021 | January 20, 2023 |
| NCT05306093 | Completed | N/A | Depressed Mood and Anhedonia in Healthy Adults | January 7, 2022 | September 1, 2022 |
| NCT05357547 | Completed | Phase 2 | Serotonin-receptor Agonism in Reward Processing | May 13, 2022 | April 18, 2023 |
| NCT05383248 | Completed | N/A | Computational Cognitive Training To Boost Reward Responsiveness In Anhedonic Patients | September 14, 2022 | November 16, 2023 |
| NCT05849675 | Completed | N/A | Pitolisant Effects on Affect and Cognition Exploratory Study (PEACE Study) | April 1, 2023 | May 8, 2024 |
| NCT06285474 | Enrolling by invitation | N/A | Investigating LIFUP in Anhedonic Depression | October 27, 2022 | April 30, 2024 |
| NCT06035562 | Enrolling by invitation | N/A | Promoting Positive Emotional Functioning in Police and Military Populations | September 5, 2023 | August 31, 2024 |
| NCT06096740 | Not yet recruiting | N/A | Psychotherapy Effects on Reward Processing in PTSD | June 1, 2024 | May 1, 2029 |
| NCT06230757 | Not yet recruiting | Phase 2 | Psilocybin for Treatment-Resistant Depression | March 1, 2024 | March 1, 2025 |
| NCT06364488 | Not yet recruiting | N/A | TrueBlue Clinical Study - Investigating the Use of a Mobile Phone App TrueBlue for Monitoring Depression and Anxiety | May 1, 2024 | July 31, 2025 |
| NCT05363527 | Recruiting | Phase 1 | Aging and Reward System Response to Inflammation and Anxiety Study | March 29, 2023 | March 15, 2026 |
| NCT05443256 | Recruiting | N/A | TMS Alteration of the Reward Positivity | August 1, 2022 | December 31, 2024 |
| NCT05455684 | Recruiting | Phase 3 | A Study of Aticaprant as Adjunctive Therapy in Adult Participants With Major Depressive Disorder (MDD) With Moderate-to-severe Anhedonia and Inadequate Response to Current Antidepressant Therapy | June 22, 2022 | October 1, 2024 |
| NCT05487885 | Recruiting | Phase 4 | Anhedonia, Development, and Emotions: Phenotyping and Therapeutics | July 22, 2022 | October 1, 2025 |
| NCT05537285 | Recruiting | N/A | Individualized Neuromodulation for Anhedonic Depression | August 1, 2022 | July 2024 |
| NCT05550532 | Recruiting | Phase 3 | A Study of Aticaprant 10 Milligrams (mg) as Adjunctive Therapy in Adult Participants With MDD With Moderate-to-severe Anhedonia and Inadequate Response to Current Antidepressant Therapy | December 6, 2022 | December 5, 2024 |
| NCT05629520 | Recruiting | A Neurobiological Model of Anhedonia | February 19, 2020 | July 30, 2025 | |
| NCT06132581 | Recruiting | N/A | Causal Role of Delta-beta Coupling for Goal-directed Behavior in Anhedonic Depression | January 24, 2024 | July 31, 2026 |
| NCT05240352 | Recruiting | N/A | Developing Brain Imaging Analysis Expertise for Personalizing Transcranial Electric Stimulation in Anhedonia Treatment of Patients With Bipolar Depression | October 6, 2022 | December 1, 2025 |
| NCT05282277 | Recruiting | Phase 4 | Examining the Effects of Estradiol on Neural and Molecular Response to Reward | April 20, 2022 | December 31, 2026 |
| NCT06270433 | Recruiting | N/A | Efficacy and Safety of Toludesvenlafaxine Hydrochloride Sustained-release Tablets Versus Desvenlafaxine Succinate Sustained-release Tablets Targeting Anhedonia in Patients With Major Depression Disorder | February 19, 2024 | December 31, 2024 |
| NCT05355337 | Recruiting | Phase 3 | Pramipexole for Anhedonic Depression | February 8, 2023 | March 2027 |
| NCT05920252 | Recruiting | N/A | A Digitally Assisted Risk Reduction Platform for Youth at High Risk for Suicide | April 7, 2024 | February 28, 2026 |
| NCT03915613 | Recruiting | Phase 1/Phase 2 | Brain Insulin Resistance in Mood Disorders | October 6, 2021 | October 5, 2024 |
| NCT05988138 | Recruiting | N/A | Prevention of Anhedonia in Children | November 10, 2023 | June 30, 2025 |
| NCT05991713 | Recruiting | N/A | Geolocation Positional System (GPS) Experience | November 2, 2023 | September 1, 2028 |
| NCT06017037 | Recruiting | Phase 1/Phase 2 | REward Processing And Citalopram Study | May 19, 2023 | May 1, 2024 |
| NCT06075771 | Recruiting | Phase 4 | Dopaminergic Therapy for Anhedonia - 2 | November 21, 2023 | January 2027 |
| NCT06080646 | Recruiting | Reward Processing and Depressive Subtypes: Identifying Neural Biotypes | June 1, 2021 | September 1, 2025 | |
| NCT05771636 | Recruiting | N/A | Mental Imagery and Psychological Well-being | March 1, 2023 | June 2025 |
| NCT05825235 | Recruiting | Phase 3 | Long-term Efficacy of Pramipexole in Anhedonic Depression | April 21, 2023 | December 31, 2025 |
| NCT05849038 | Recruiting | Phase 2 | Inflammation and Depression in People With HIV | December 11, 2023 | November 2027 |
| NCT06391593 | Recruiting | Phase 2 | PD, PK, and Safety of ALTO-203 in Patients With MDD | March 25, 2024 | May 2025 |
| NCT05869708 | Recruiting | N/A | PRISM Neurofeedback Training for MDD Anhedonic Patients | July 1, 2023 | May 1, 2025 |
| NCT05870501 | Recruiting | N/A | Synaptic Imaging and Network Activity in Treatment Resistant Depression | October 20, 2021 | September 11, 2023 |
| NCT03715400 | Suspended | N/A | Mobile Virtual Positive Experiences for Anhedonia | September 1, 2018 | January 1, 2021 |
| NCT02236702 | Terminated | Kappa Opioid Receptor Imaging in Depression (KOR Depression) | August 2014 | February 2016 | |
| NCT04793438 | Unknown status | N/A | Motive-specific Intervention for Negative Symptoms in Schizophrenia | January 1, 2021 | June 30, 2022 |
| NCT02773212 | Unknown status | Phase 2 | Targeting Anhedonia in Cocaine Use Disorder | February 1, 2017 | April 2022 |
| NCT05234476 | Unknown status | N/A | Behavioral Activation Plus Savoring for University Students | September 6, 2021 | June 1, 2022 |
| NCT05507385 | Withdrawn | N/A | Imagine a Brighter Future: An Intervention to Improve Positive Emotions in Young People | September 2022 | June 30, 2024 |
| NCT05601648 | Withdrawn | Phase 2 | PET Synaptogenesis After Psilocybin In DEpression Recovery | July 1, 2023 | July 1, 2025 |
- HPO Human Phenotype ID (Human Phenotype Ontology)
- HP:0012154
- MeSH unique ID (MeSH (Medical Subject Headings))
- D059445