Chronic thromboembolic pulmonary hypertension

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Information
Disease name
Chronic thromboembolic pulmonary hypertension
Disease ID
Description
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
Genes Mutation Description Source Links
NCT ID Status Phase Summary Start date Completion date
NCT05996302 Active, not recruiting N/A HA Residents With PVD, 6MWD Assessed at HA (2840m) vs LA (Sea Level) July 5, 2023 December 31, 2023
NCT06072417 Active, not recruiting N/A HA Residents With PVD, SDB Assessed at HA (2840m) vs LA (Sea Level) September 22, 2023 December 31, 2023
NCT06084559 Active, not recruiting N/A HA Residents With PVD, Pulmonary Artery Pressure (PAP) Assessed at HA (2840m) With and Without Supplemental Oxygen Therapy (SOT) July 5, 2023 December 31, 2023
NCT03729544 Active, not recruiting N/A Computerized Decision Support to Increase Detection of Chronic Thromboembolic Pulmonary Hypertension in Patients With Prior Pulmonary Embolism March 1, 2019 December 30, 2024
NCT06092424 Active, not recruiting N/A High Altitude (HA) Residents With Pulmonary Vascular Diseseases (PVD), Pulmonary Artery Pressure (PAP) Assessed at HA (2840m) vs Sea Level (LA) September 23, 2023 December 31, 2024
NCT06003244 Active, not recruiting N/A High Altitude (HA) Residents With Pulmonary Vascular Diseases (PVD), 6 Minute Walk Distance (6MWD) Assessed at 2840m (HA) With and Without Supplemental Oxygen Therapy (SOT) September 23, 2023 December 31, 2023
NCT04881214 Active, not recruiting N/A COVID-19 Pneumonia: Pulmonary Physiology, Health-related Quality of Life and Benefit of a Rehabilitation Program July 1, 2020 June 30, 2023
NCT02111980 Completed N/A RF Surgical Sponge-Detecting System on the Function of Pacemakers and Implantable Cardioverter Defibrillators March 2014 May 2015
NCT02114047 Completed Pulmonary Perfusion Heterogeneity in Patients With CTEPH Using Functional PET Imaging February 2014 January 2017
NCT02555137 Completed Early Non-invasive Detection of CTEPH After Pulmonary Embolism February 1, 2016 December 1, 2019
NCT02565030 Completed Chronic Thrombo-embolic Pulmonary Hypertension: Classification and Long Term Outcome February 2015 October 2021
NCT05861479 Completed Prognostic Value of Estimated Plasma Volume in Pulmonary Hypertension January 1, 2015 April 1, 2023
NCT02634203 Completed N/A Riociguat Versus Balloon Pulmonary Angioplasty in Non-operable Chronic thromboEmbolic Pulmonary Hypertension January 19, 2016 January 27, 2020
NCT02656238 Completed New International CTEPH Database February 2015 January 2020
NCT03422328 Completed Phase 3 A Clinical Study to Investigate the Long-term Safety of the Drug Macitentan in Patients With Pulmonary Hypertension Who Were Previously Treated With Macitentan in Clinical Studies. April 5, 2018 December 27, 2023
NCT00313222 Completed Phase 3 Bosentan Effects in Inoperable Forms of Chronic Thromboembolic Pulmonary Hypertension October 2005 March 2007
NCT00657722 Completed N/A Identification of Criteria of the Success of the Endarterectomy in Chronic Pulmonary Post Embolic Hypertension January 2008 November 2011
NCT00747045 Completed N/A Lung Protective Ventilation in Pulmonary Thromboendarterectomy (PTE) Patients August 2008 March 2011
NCT02021292 Completed Phase 2 Clinical Study to Assess the Efficacy, Safety and Tolerability of Macitentan in Subjects With Inoperable Chronic Thromboembolic Pulmonary Hypertension August 20, 2014 September 28, 2016
NCT02060721 Completed Phase 2 Clinical Study to Assess the Safety, Tolerability and Efficacy of Macitentan in Subjects With Inoperable Chronic Thromboembolic Pulmonary Hypertension February 3, 2015 March 21, 2022
NCT02094001 Completed Phase 2 Pilot Study to Evaluate Right Ventricular Function With Riociguat in CTEPH May 2014 June 2016
NCT03199131 Completed N/A The Right Ventricle in Chronic Pressure Overload: Identifying Novel Molecular Targets for Functional Imaging February 20, 2017 October 20, 2018
NCT03245268 Completed International BPA Registry March 2, 2018 March 31, 2022
NCT03786367 Completed Dyspnea in Chronic Thromboembolic Pulmonary Hypertension November 1, 2018 January 1, 2023
NCT03757481 Completed N/A Long-term Outcome After Heparin and Edoxaban Versus Heparin Plus Vit K Antagonists for Acute DVT and PE January 1, 2018 March 3, 2020
NCT03074539 Completed N/A Sleep-Disordered Breathing in Chronic Thromboembolic Pulmonary Hypertension February 1, 2017 December 31, 2022
NCT04773028 Completed The Role of Matrix Metalloproteinase 2 and 9 Enzymes in Developing Chronic Thromboembolic Pulmonary Hypertension July 1, 2020 May 4, 2021
NCT04663230 Completed Right Atrial Fibrosis in Pulmonary Hypertension April 30, 2021 November 30, 2023
NCT03198910 Completed Retrospective Data Analysis of Data From the Zurich PH Registry June 2, 2017 December 31, 2018
NCT05568927 Enrolling by invitation Validation of SEARCH, a Novel Hierarchical Algorithm to Define Long-term Outcomes After Pulmonary Embolism November 15, 2022 September 2024
NCT05618093 Enrolling by invitation N/A Non-Invasive Measurement of Cardiac Output and Stroke Volume in PAH/CTEPH March 2, 2023 December 31, 2025
NCT03388476 Enrolling by invitation Endtidal Carbon Dioxide for Earlier Detection of Pulmonary Hypertension May 2, 2018 January 1, 2035
NCT06209710 Enrolling by invitation Phase 2/Phase 3 Balloon Pulmonary Angioplasty vs. Combined Approach With Pulmonary Artery Denervation in CTEPH: Effectiveness Comparison April 1, 2024 December 2025
NCT06384534 Not yet recruiting N/A Exercise Performance on Ambient Air vs. Low-Flow Oxygen Therapy in Pulmonary Vascular Disease (PVD) May 2024 November 2025
NCT06060366 Not yet recruiting Impact of Pulmonary Endarterectomy on Sleep-Related Breathing Disorders in CTEPH: The IPES Trial December 20, 2023 November 20, 2024
NCT06081881 Not yet recruiting Chronic Thromboembolic Pulmonary Hypertension After Pulmonary Embolism January 1, 2024 January 1, 2027
NCT05133713 Recruiting Ventilation and Perfusion Scan in Pulmonary Embolism Following Catheter Directed Thrombectomy Versus Anticoagulation Alone April 1, 2022 January 1, 2024
NCT05311072 Recruiting Change-a Multi-center Chronic Thromboembolic Pulmonary Hypertension (CTEPH) Database in China October 1, 2015 December 31, 2027
NCT05340023 Recruiting Proteomic Pattern Associated With the Diagnosis of Chronic Thromboembolic Pulmonary Hypertension November 9, 2022 December 2025
NCT03579862 Recruiting Identification of Heritable CTEPH December 25, 2013 December 31, 2023
NCT04954742 Recruiting Phase 4 Effects of Riociguat on RIght VEntricular Size and Function in PAH and CTEPH April 13, 2022 March 2026
NCT05110066 Recruiting N/A BPA vs. PEA in CTEPH April 1, 2024 April 1, 2028
NCT05179356 Recruiting Phase 2 Dapagliflozin in Pulmonary Arterial Hypertension January 1, 2023 September 2024
NCT04444973 Recruiting RV Conductance Catheter Assessment During Balloon Pulmonary Angioplasty January 1, 2022 December 31, 2024
NCT05629052 Recruiting TrEatment Approach in the Multimodal Era Registry April 12, 2023 April 2028
NCT05843500 Recruiting Chronic Thromboembolic Disease Registry August 1, 2023 July 1, 2028
NCT04052243 Recruiting N/A Hemodynamic Effects of BPA at Rest and During Exercise in CTEPH January 1, 2021 June 30, 2024
NCT04071327 Recruiting Pulmonary Hypertension Association Registry October 2015 October 2025
NCT06038630 Recruiting Phase 2 129Xe MRI Cardiopulmonary January 12, 2024 June 30, 2028
NCT06286891 Recruiting Frailty, Physical Capacity and Lung Function in Postoperative Pulmonary Endarterectomy Patients February 29, 2024 September 30, 2025
NCT02061787 Recruiting the Application of Cardiopulmonary Exercise Testing in Assessment Outcome of Patients With Pulmonary Hypertension September 2010 September 8, 2030
NCT03959748 Recruiting DataBase of pulmoNary hyPertesion in PoLish Population - BNP-PL March 1, 2018 February 28, 2028
NCT04206852 Recruiting Safety and Efficacy of Balloon Pulmonary Angioplasty in China May 11, 2018 May 11, 2028
NCT04808596 Recruiting Pulmonary Hypertension Biorepository and Registry August 10, 2020 July 31, 2026
NCT00477724 Recruiting N/A Latent Pulmonary Hypertension (PH) in Chronic Thromboembolic Pulmonary Hypertension (CTEPH )After Endarterectomy and Influence of Exercise and Respiratory Therapy June 2007 December 2023
NCT03273257 Terminated Phase 2 Riociguat in Patients With Operable CTEPH Prior to Pulmonary Endarterectomy (PEA Bridging Study) August 17, 2018 May 5, 2020
NCT04271475 Terminated Phase 3 A Study to Evaluate Efficacy and Safety of Macitentan 75 mg in Inoperable or Persistent/Recurrent Chronic Thromboembolic Pulmonary Hypertension July 7, 2020 December 21, 2023
NCT02583906 Terminated N/A Sleep Disordered Breathing in Precapillary Pulmonary Hypertension: Effect of CPAP Treatment April 2014 May 2019
NCT03689244 Terminated Phase 3 A Study to Find Out if Selexipag is Effective and Safe in Patients With Chronic Thromboembolic Pulmonary Hypertension When the Disease is Inoperable or Persistent/Recurrent After Surgery and/or Interventional Treatment January 23, 2019 June 7, 2022
NCT00348803 Unknown status Gene Mutations in Secondary Pulmonary Hypertension
NCT03349164 Unknown status Registry of Patients With Chronic Thromboembolic Pulmonary Hypertension in Novosibirsk Region January 1, 2017 March 10, 2018
NCT03795740 Unknown status N/A Pulmonary Endarterectomy Guided by CT Scanning for Patients With Chronic Thromboembolic Pulmonary Hypertension----PEACT February 1, 2017 December 31, 2022
NCT03806907 Unknown status Iodine Subtraction Mapping in the Diagnosis of Chronic Pulmonary Thromboembolic Disease April 1, 2019 August 30, 2020
NCT04007653 Unknown status Long-term Outcome After Edoxaban Versus Vitamin K Antagonists for Acute VTE April 25, 2017 December 31, 2020
NCT04081012 Unknown status N/A N-acetyl Cysteine in Post-reperfusion Pulmonary Injury in Chronic Thromboembolic Pulmonary Hypertension. May 21, 2019 May 21, 2023
NCT04326777 Unknown status N/A Clinical Study of Balloon Pulmonary Angioplasty for Patients With Chronic Thromboembolic Pulmonary Hypertension April 15, 2020 April 2023
NCT03195543 Unknown status Assessment of Blood Coagulation Disorders in Patients With Pulmonary Hypertension March 12, 2015 December 2020
NCT04681014 Unknown status CTEPH in Patients With Prior Pulmonary Embolism and Risk Score Validation January 21, 2016 July 31, 2022
NCT03102294 Unknown status N/A Inspiratory Muscle Training in Chronic Thromboembolic Pulmonary Hypertension September 1, 2017 April 30, 2019
NCT04777448 Unknown status N/A Optimized Management After Balloon Pulmonary Angioplasty in Chronic Thromboembolic Pulmonary Hypertension April 2021 July 2023
NCT02964390 Unknown status N/A Balloon Pulmonary Angioplasty in Non-operable CTEPH Patients July 2013 December 2023
NCT02745106 Unknown status Phase 2 Interventional Treatment of Residual Pulmonary Hypertension in Patients After Pulmonary Thromboendarterectomy August 2015 February 2017
NCT02660463 Unknown status Prospective Registry to Evaluate the Effective Incidence of Chronic Thromboembolic Pulmonary Hypertension in Germany January 2016 December 2016
NCT02426203 Unknown status 3D Echocardiographic Assessment of RV Function in Patients Undergoing Pulmonary Endarterectomy May 2015 June 2016
NCT02268630 Unknown status Long Term Outcomes of Venous Thromboembolism January 2014 October 2023
NCT03470207 Unknown status N/A The Prospective Risk Factor Evaluation & Discovery In CTEPH Study April 17, 2018 August 2021
NCT01417338 Unknown status Registry for Pulmonary Hypertension in China August 2009 December 2020
NCT01163422 Unknown status N/A Right Ventricular Resynchronization Therapy July 2010 July 2012
NCT05693779 Withdrawn N/A Exercise Therapy After Pulmonary Thromboendarterectomy or Balloon Pulmonary Angioplasty for Chronic Thromboembolic Pulmonary Hypertension May 2023 February 2024
OrphaNumber from OrphaNet (Orphanet)
70591