Tympanic Membrane Perforation

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Information
Disease name
Tympanic Membrane Perforation
Disease ID
Description
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
Genes Mutation Description Source Links
NCT ID Status Phase Summary Start date Completion date
NCT03922295 Completed N/A Endoscopic Tympanoplasty: Single Versus Double Flap Technique August 24, 2017 February 20, 2019
NCT02019888 Completed Wide Frequency Band Test of Hearing in Veterans December 1, 2014 January 31, 2020
NCT02307916 Completed Phase 2 Fibroblast Growth Factor Regeneration of Tympanic Membrane Perforations October 2016 March 2020
NCT02331797 Completed N/A Endoscopic Overlay Tympanoplasty for TM Perforation December 2014 October 2017
NCT05605262 Completed Phase 2/Phase 3 Effects of 100% Medical Grade Manuka Honey on Tympanic Membrane Reconstruction Healing. June 13, 2021 September 29, 2022
NCT02550314 Completed Phase 3 A Study on the Regenerative Treatment of Tympanic Membrane With NPC-18 and FBG-18 March 2015 July 2016
NCT03569969 Completed N/A Comparison Tympanoplasty With Membrane Amniotic and Autologous Fascia January 1, 2016 December 1, 2017
NCT00714064 Completed Phase 3 PneuMum: Pneumococcal Vaccination of Australian Indigenous Mothers June 2006 July 2011
NCT02120651 Completed Phase 3 Fibrin Monomer Compared With Hemostatic Sponge in the Integrity of the Graft During Tympanoplasty January 2012 January 2014
NCT02296944 Completed Anatomical and Functional Results of Surgery of the Tympanic Membrane Perforation of the Child January 6, 2015 December 8, 2017
NCT06257602 Not yet recruiting Microscopic Versus Endoscopic Tympanoplasty March 30, 2024 December 30, 2025
NCT04635228 Recruiting Biodesign® Otologic Repair Graft September 29, 2021 March 2026
NCT05849844 Recruiting N/A Tympanoseal Clinical Study January 5, 2024 April 20, 2026
NCT04960384 Recruiting Phase 2 Fibroblast Growth Factor Regeneration of Tympanic Membrane Perforations May 27, 2022 June 2025
NCT06260618 Recruiting N/A Effect of Chitodex Gel in Tympanoplasty Surgery November 20, 2021 May 13, 2024
NCT01766856 Terminated Eustachian Tube Function and Myringoplasty/Tympanoplasty November 2012 November 2, 2017
NCT03837665 Unknown status Phase 1/Phase 2 Efficacy of Platelet Enriched Plasma in Preventing Surgery for Patients With Chronic Tympanic Membrane Perforation May 2, 2018 June 30, 2019
NCT00310349 Unknown status Phase 3 PneuMum: Pneumococcal Vaccination of Australian Indigenous Mothers to See if it Protects Their Babies From Ear Disease March 2006 January 2009
NCT01958749 Unknown status N/A Fat Graft Myringoplasty With and Without Platelet Rich Plasma (PRP) for Treating Smaller Tympanic Membrane Perforations
NCT03416725 Unknown status Evaluation of Prognostic Factors in Tympanoplasty March 1, 2018 March 1, 2020
NCT00222417 Unknown status Audiometric Parameters in Conductive Hearing Loss and Middle Ear Disease September 2002 December 2014
NCT04428463 Unknown status N/A Repair of Tympanic Membrane Perforation Using Tachosil Under Local Anesthesia June 30, 2020 June 2021
NCT04687995 Unknown status N/A Tragal Perichondrium Versus Pretragal Fascial (SMAS) Graft for Endoscopic Myringoplasty January 2021 November 2022
NCT04761562 Unknown status Phase 2/Phase 3 Use of Autologous Plasma Rich in Platelets and Extracellular Vesicles in the Surgical Treatment of Chronic Middle Ear Infections February 14, 2021 September 30, 2023
NCT05086718 Unknown status N/A Composite Cartilage Perichondrium Graft for Air Bone Gap Closure in Chronic Suppurative Otitis Media (CSOM) Without Posterior Meatal Flap September 1, 2021 September 30, 2022
NCT05282810 Unknown status Cartilage Versus Temporalis Fascia Graft in Tympanoplasty for Recurrent Tympanic Membrane Perforation '' Comparative Study '' April 2022 May 2023
NCT03904316 Withdrawn Phase 4 Use of Biodesign® Otologic Graft in Tympanoplasty October 3, 2018 July 1, 2022
NCT03028272 Withdrawn N/A Hearing Results and Post Surgical Outcomes Using Amniotic Membrane Allograft vs. Fascia for Tympanoplasty January 1, 2017 December 31, 2020
MeSH unique ID (MeSH (Medical Subject Headings))
D018058