Epilepsies, Partial

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Information
Disease name
Epilepsies, Partial
Disease ID
Description
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
Genes Mutation Description Source Links
NCT ID Status Phase Summary Start date Completion date
NCT03689114 Active, not recruiting Phase 4 Low vs. Standard Daily Doses of Antiepileptic Drugs in Newly Diagnosed, Previously Untreated Epilepsy(STANDLOW) May 10, 2021 August 31, 2024
NCT00072813 Completed MRI in Autosomal Dominant Partial Epilepsy With Auditory Features November 10, 2003
NCT00143143 Completed Phase 3 Pregabalin Open-Label Extension Trial in Patients With Partial Seizures September 2001 February 2006
NCT00151879 Completed Phase 2/Phase 3 Safety and Tolerability of Intravenous SPM 927 as Replacement for Oral SPM 927 in Subjects With Partial Seizures February 2005 May 2006
NCT00210522 Completed Phase 2 An Open-Label Extension Study of the Effectiveness and Safety of the Investigational Compound RWJ-333369 in Patients With Epilepsy May 2005 June 2010
NCT00210652 Completed Phase 2 An Open-Label Extension Study to Evaluate the Safety and Effectiveness of RWJ 333369 in Patients With Epilepsy July 2004 March 2010
NCT00212745 Completed Phase 1/Phase 2 Pilot Trial of a Behavioral Treatment for Epilepsy February 2004 March 2009
NCT00230698 Completed Phase 3 A Study of the Effectiveness and Safety of Topiramate Monotherapy in Patients With Recently Diagnosed Partial-Onset Seizure November 1995 August 2002
NCT00231556 Completed Phase 3 A Study on Safety and Efficacy of Two Doses of Topiramate as Monotherapy in the Treatment of Newly Diagnosed or Recurrent Epilepsy July 1999 September 2003
NCT00236691 Completed Phase 2 A Study of the Efficacy and Safety of Topiramate as add-on Therapy in the Treatment of Epilepsy Patients With Difficult to Treat, Partial-onset Seizures. July 1988 December 1990
NCT00236730 Completed Phase 2 A Study of the Efficacy and Safety of Topiramate in the Treatment of Patients With Difficult to Control Epilepsy June 1988 December 1990
NCT00050934 Completed Phase 3 Pediatric Epilepsy Study June 2002 June 2004
NCT00236847 Completed Phase 2 A Study of the Efficacy and Safety of Topiramate in the Treatment of Patients With Epilepsy. December 1989 July 1993
NCT00236860 Completed Phase 2 A Study of the Efficacy and Safety of Topiramate as add-on Therapy in the Treatment of Epilepsy Patients With Difficult to Treat, Partial-onset Seizures May 1989 February 1992
NCT00236873 Completed Phase 2 A Study of the Efficacy and Safety of Topiramate as add-on Therapy in the Treatment of Epilepsy Patients With Difficult to Treat, Partial-onset Seizures. October 1989 May 1993
NCT00236886 Completed Phase 3 Prospective Pilot Study on Metabolism and Weight Changes in Topiramate-Treated Epilepsy Patients May 1998 June 2000
NCT00266604 Completed Phase 4 A Study to Evaluate the Dosing, Effectiveness and Safety of Topiramate for the Treatment of Epilepsy December 2005 June 2007
NCT00280696 Completed Phase 3 A Double-blind Confirmatory Trial of Levetiracetam in Epilepsy Patients With Partial Onset Seizures November 2005 November 2007
NCT00319501 Completed Phase 3 Efficacy and Safety of Diazepam in the Management of Refractory Epilepsy in Selected Patients Who Require Intermittent Medical Intervention for Acute Repetitive Seizures. January 2006 July 2014
NCT00351611 Completed Phase 4 Vision Testing in Patients With Partial Seizures Receiving Either Lyrica or Placebo July 26, 2006 February 4, 2020
NCT00236743 Completed Phase 3 A Study of the Effectiveness and Safety of Topiramate in the Treatment of Children With Epilepsy June 1994 October 2000
NCT00643136 Completed Phase 3 A Study of Lyrica as Treatment for Sleep Problems in Patients With Sleep Problems and Seizures November 2002 June 2004
NCT00771927 Completed Post-Authorization Safety Study to Assess the Safety of Vimpat as add-on Therapy in Patients With Partial-onset Seizures October 2008 March 2012
NCT00772603 Completed Phase 3 Evaluation of Efficacy and Safety of OXC XR as Adjunctive Therapy for Partial Seizures November 2008 November 2010
NCT00918047 Completed Phase 1 Study of PK and Safety of OXC (Oxcarbazepine) XR (Extended Release) as Adjunctive Therapy in Pediatric Epilepsy Patients June 2009 November 2010
NCT00991757 Completed Phase 3 An Open-Label Extension Study to Evaluate the Safety and Tolerability of RWJ 333369 as Adjunctive Therapy in Patients 16 Years and Older With Partial Onset Seizures. February 2007 October 2010
NCT01098162 Completed Vimpat® Added as Adjunctive Therapy to One Baseline Antiepileptic Drug March 2010 July 2013
NCT01262677 Completed Phase 3 Once-A-Day Pregabalin For Partial Seizures February 17, 2011 August 1, 2012
NCT01441401 Completed Safety and Efficacy of Gabapen for Pediatric (Regulatory Post Marketing Commitment Plan) December 2011 September 2014
NCT01663545 Completed Brain P-gp and Inflammation in People With Epilepsy July 31, 2012 October 4, 2017
NCT01745952 Completed N/A Treatment of Difficult to Control Focal Epilepsy With Repetitive Transcranial Magnetic Stimulation (rTMS) November 2012 December 31, 2015
NCT03200769 Completed N/A Study of the Efficacy of the Treatment of Sleep Apnea Syndrome by CPAP in Pharmacoresistant Epilepsy July 21, 2014 July 2021
NCT03446664 Completed N/A Microburst Vagus Nerve Stimulator (VNS) Therapy Feasibility Study February 27, 2018 October 27, 2021
NCT05273398 Completed Phase 4 Effects of Diazepam on RNS Detections March 1, 2022 November 10, 2022
NCT00437281 Completed Phase 1/Phase 2 Safety, Tolerability, and Pharmacokinetic Study of Pregabalin in Pediatric Patients With Partial Onset Seizures April 2007 November 2012
NCT00448916 Completed Phase 3 Open-Label Extension Study Of Safety And Tolerability Of Pregabalin In Pediatric Patients With Partial-Onset Seizures May 2007 October 2013
NCT00512317 Completed Phase 2 Open-label Extension to Protocol 1042-0600 June 2007 September 2013
NCT00537940 Completed Phase 4 Comparative Study Of Pregabalin And Gabapentin As Adjunctive Therapy In Subjects With Partial Seizures February 2008 July 2013
NCT00567268 Completed Drug Use Investigation Of Gabapentin August 2007 May 2014
NCT00603473 Completed Phase 3 A Phase III Open-Label Study Of Gabapentin As Adjunctive Therapy In Japanese Pediatric Patients With Partial Seizures January 2008 December 2009
NCT00620555 Completed Phase 3 A Phase III Open-Label Extension Study Of Gabapentin As Adjunctive Therapy In Japanese Pediatric Patients With Partial Seizures May 2008 December 2010
NCT04309812 Enrolling by invitation Early Phase 1 Transcranial Direct Current to Treat Epilepsy at Home May 26, 2021 July 26, 2023
NCT05248269 Enrolling by invitation N/A Thermocoagulation in Drug Resistant Focal Epilepsy February 7, 2022 December 1, 2024
NCT03559673 No longer available Compassionate Use Program With Lacosamide in Patients With Partial-onset or Generalized Tonic-clonic Seizures
NCT06374966 Not yet recruiting Real-world Study of Efficacy and Safety of Zonisamide in add-on Therapy for Patients With Focal Epilepsy April 2024 December 2025
NCT05015868 Recruiting N/A Contribution of Genetics, Non-invasive Methods and Neuropsychology in Focal Cryptogenic Epilepsies July 15, 2021 December 31, 2024
NCT03949478 Recruiting Phase 2 Treating Postictal Symptoms Using Ibuprofen and Nifedipine February 1, 2021 March 1, 2025
NCT03054961 Recruiting Cerebral Oxygen Saturation and Cytochrome Oxidase REDOX State in Children With Epilepsy: A Pilot Study February 10, 2017 February 9, 2025
NCT00524030 Terminated Phase 3 Efficacy And Safety Study Of Pregabalin (Lyrica) As Monotherapy In Patients With Partial Seizures September 2007 June 2011
NCT00215215 Terminated Phase 4 Effectiveness Study Comparing Treatment With Drug(s) or Adjunctive VNS Therapy for Pharmacoresistant Partial Seizures February 2005 November 2007
NCT02635633 Terminated N/A Continuous Thetaburst Stimulation for the Treatment of Refractory Epilepsy - Safety, Feasibility and Proof-of-concept August 2015 September 2018
NCT03916848 Unknown status N/A Novel Network Analysis of Intracranial Stereoelectroencephalography June 16, 2019 April 2022
NCT03882151 Unknown status N/A Added Value of Automated Electrical Source Localization (EPILOG PreOp®) to Presurgical Evaluation of Refractory Epilepsy January 15, 2019 December 31, 2020
NCT00422110 Withdrawn Phase 2/Phase 3 A Study to Evaluate the Efficacy and Safety of Seletracetam in Adult Patients With Refractory Partial Onset Seizures May 2008
MeSH unique ID (MeSH (Medical Subject Headings))
D004828