Carcinoma of unknown primary

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Information
Disease name
Carcinoma of unknown primary
Disease ID
Description
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
Genes Mutation Description Source Links
NCT ID Status Phase Summary Start date Completion date
NCT03391973 Active, not recruiting Phase 2 Pembrolizumab in Patients With Poor-Prognosis Carcinoma of Unknown Primary Site (CUP) August 24, 2018 December 30, 2024
NCT02721732 Active, not recruiting Phase 2 Pembrolizumab in Treating Patients With Rare Tumors That Cannot Be Removed by Surgery or Are Metastatic August 15, 2016 December 31, 2025
NCT01366144 Active, not recruiting Phase 1 Veliparib, Paclitaxel, and Carboplatin in Treating Patients With Solid Tumors That Are Metastatic or Cannot Be Removed by Surgery and Liver or Kidney Dysfunction June 20, 2011 March 5, 2025
NCT00003943 Completed Phase 2 Combination Chemotherapy Plus Peripheral Stem Cell Transplantation in Treating Patients With Metastatic Cancer. September 1998 February 2003
NCT00004005 Completed Phase 2 Irinotecan Followed By Fluorouracil and Leucovorin in Treating Patients With Stage III or Stage IV Colorectal Carcinoma (Cancer), Other Refractory Carcinoma, or Metastatic Adenoma (Cancer) of Unknown Primary Origin September 1998 October 2005
NCT00004922 Completed Phase 2 Irinotecan in Treating Patients With Advanced Neuroendocrine Tumors June 1999 June 2002
NCT00006361 Completed Phase 2 SU5416 in Treating Patients With Advanced or Recurrent Cancer of the Head and Neck December 2000
NCT00014456 Completed Phase 1 Combination Chemotherapy Plus Filgrastim in Treating Patients With Advanced Solid Tumors March 2000 October 2005
NCT00047125 Completed Phase 3 Radiation Therapy in Treating Patients With Metastases to the Lymph Nodes in the Neck From an Unknown Primary Tumor July 2002
NCT00066781 Completed Phase 2 Gemcitabine and Irinotecan in Treating Patients With Cancer of Unknown Primary February 2004 March 2009
NCT00002507 Completed Phase 3 Radiation Therapy and Chemotherapy in Treating Patients With Head and Neck Cancer November 1992 October 2002
NCT00003582 Completed Phase 1/Phase 2 Radiation Therapy, Combination Chemotherapy, and Amifostine in Treating Patients With Head and Neck Cancer May 1988 December 1996
NCT00003657 Completed Phase 2 High-dose ICE With Amifostine July 1998 June 2002
NCT00357630 Completed Phase 2 Gemcitabine in Treating Patients With Metastatic Cancer of Unknown Primary June 2006
NCT00388024 Completed PET Scans and CT Scans in Patients With Locally Advanced Head and Neck Cancer Undergoing Chemotherapy and Radiation Therapy February 2006 January 2015
NCT00873119 Completed Phase 2 Belinostat, Carboplatin and Paclitaxel (BelCaP) Compared to Carboplatin and Paclitaxel in Patients With Cancer of Unknown Primary February 2009 December 2012
NCT04189107 Completed Phase 3 Postoperative Pain, Why Still in Hospital and DAOH Following TORS for SCCUP & OSAS August 18, 2020 November 9, 2022
NCT04985357 Not yet recruiting Defining the Clinical Potential of Mass Response as a Biomarker for Patient Tumor Sensitivity to Drugs June 2024 May 2030
NCT05144698 Recruiting Phase 1/Phase 2 RAPA-201 Therapy of Solid Tumors August 1, 2021 December 31, 2024
NCT03010150 Recruiting Blood Tests and Questionnaires in Studying Adherence to Preventative Swallowing Exercises in Participants With Metastatic Head and Neck Cancer December 29, 2016 December 31, 2028
NCT03740503 Recruiting Genomic Investigation of Unusual Responders November 1, 2013 November 2024
NCT05887492 Recruiting Phase 1/Phase 2 Study of TNG260 and an Anti-PD Antibody in STK11 Mutated Solid Tumors June 12, 2023 June 2025
NCT04475640 Recruiting N/A Cancer Genetic Testing in Ethnic Populations December 13, 2019 October 15, 2024
NCT04802876 Recruiting Phase 2 Efficacy of Tislelizumab and Spartalizumab Across Multiple Cancer-types in Patients With PD1-high mRNA Expressing Tumors April 12, 2021 March 31, 2027
NCT05461430 Recruiting Mass Response of Tumor Cells as a Biomarker for Rapid Therapy Guidance (TraveraRTGx) July 15, 2022 July 2026
NCT00148135 Terminated Phase 2 Combination of Carboplatin, Gemcitabine, and Capecitabine in Patients With Carcinoma of Unknown Primary Site May 2001 October 2007
NCT00112619 Terminated Phase 1 Topotecan in Treating Young Patients With Neoplastic Meningitis Due to Leukemia, Lymphoma, or Solid Tumors August 2005
NCT00022178 Unknown status Phase 3 Combination Chemotherapy in Treating Patients With Metastatic Cancer of an Unknown Site of Origin December 1998
NCT00003558 Unknown status Phase 3 Chemotherapy in Treating Patients With Cancer of Unknown Primary Origin August 1998
NCT02764216 Unknown status Phase 2 Elective Mucosal Irradiation in Head-and-Neck Cancer of Unknown Primary January 2010 December 2020
NCT02590055 Unknown status Phase 2 Phase 2 Study of Gemcitabine and Docetaxel Combination Chemotherapy in Patients With Carcinoma of Unknown Primary October 2015 September 2019
NCT00119314 Withdrawn Phase 2 Gemcitabine, Docetaxel, and Capecitabine in Treating Patients With Cancer of Unknown Primary Origin July 2004 July 2005