Chronic constipation

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Information
Disease name
Chronic constipation
Disease ID
Description
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
Genes Mutation Description Source Links
NCT ID Status Phase Summary Start date Completion date
NCT06354855 Active, not recruiting N/A "Which Type of Exercise is More Effective in Chronic Constipation? February 15, 2024 December 2024
NCT03119584 Active, not recruiting Phase 4 Efficacy of Linaclotide in Type II Diabetics With Chronic Constipation September 1, 2015 January 30, 2025
NCT00255372 Completed Phase 3 To Determine the Effect of Forlax® Treatment in Children With Chronic Constipation Who May Also Suffer From Soiling/ Faecal Incontinence. April 2005 May 20, 2008
NCT00256984 Completed Phase 4 Study of Stapled Transanal Rectal Resection (STARR) Surgery in Refractory Constipation Associated With Obstructive Defecation Syndrome (ODS) October 1, 2005 June 1, 2008
NCT00354575 Completed Phase 2 Effect of Chinese Herb on Chronic Constipation for Residents in Long-Term Care Units September 2006 June 2008
NCT00391820 Completed Phase 2 Evaluate the Safety and Efficacy of a 5-HT4 Agonist in Chronic Constipation (ACCORD Trial) October 2006 May 2007
NCT00402337 Completed Phase 2 Dose-range-finding, Phase 2 Trial of Oral Linaclotide Acetate Administered to Patients With Chronic Constipation November 2006 February 2008
NCT00403819 Completed Phase 3 Study to Examine the Efficacy and Safety of Movicol in the Treatment of Chronic Constipation in Children April 2002 April 2003
NCT00403897 Completed Phase 3 An Open Single Centre Study To Assess Treatment of Chronic Constipation in Children August 2001 January 2003
NCT00404040 Completed Phase 2 Movicol in Childhood Constipation (ProMotion Study) October 2000 July 2002
NCT00522093 Completed N/A Efficacy and Safety of TJ-100 in the Treatment of Chronic Constipation August 2007 March 2008
NCT00576511 Completed Phase 2 Effect of Prucalopride in Patients With Severe Chronic Idiopathic Constipation December 1994 February 1996
NCT00730171 Completed Phase 3 An Open-label, Long-term Safety Study of Linaclotide in Patients With Chronic Constipation or Irritable Bowel Syndrome With Constipation September 2008 March 2012
NCT00149877 Completed Phase 4 Efficacy, Safety and Tolerability of Tegaserod in Patients With Chronic Constipation April 2004 February 2006
NCT01642914 Completed Phase 3 Safety and Efficacy of Linaclotide in Patients With Chronic Constipation and Prominent Abdominal Bloating August 2012 August 2013
NCT01707667 Completed Phase 4 Study to Investigate Prucalopride vs. Polyethylene Glycol 3350 on Colon Activity February 27, 2013 November 27, 2013
NCT01793753 Completed Effect of Propofol on Internal Anal Sphincter Pressure During ARM October 2012 June 2013
NCT01867944 Completed N/A Perineal Self-Acupressure June 2013
NCT01937663 Completed Phase 2 A Single-blind, Dose-tapering Study of KWA-0711 in Patients With Chronic Constipation
NCT01938196 Completed Phase 2 A Single-blind, Dose-titration Study of KWA-0711 in Patients With Chronic Constipation
NCT02137642 Completed Phase 1 Study to Evaluate the Effects of RM-131 in Patients With Chronic Constipation August 2014 November 2014
NCT02281630 Completed Phase 2 Phase II Dose-Finding Study of KWA-0711 in Patients With Chronic Constipation (CC) October 15, 2014
NCT02321124 Completed N/A Connective Tissue Manipulation Improves Symptoms and Quality of Life in Patients With Chronic Constipation August 2012 July 2015
NCT02343978 Completed Phase 2 Phase II Study of KWA-0711 in Patients With Chronic Constipation (CC) December 26, 2014
NCT02425722 Completed Phase 2 A Study to Evaluate Dose Responses of Efficacy and Safety of ASP0456 in Patient With Chronic Constipation April 13, 2015 October 31, 2015
NCT02809105 Completed Phase 3 A Study of Oral Dosing of ASP0456 in Patients With Chronic Constipation June 24, 2016 November 10, 2017
NCT02961556 Completed Phase 3 General Clinical Study of AJG555 in Pediatric Patients With Chronic Constipation November 15, 2016 August 4, 2017
NCT03117322 Completed Phase 4 Synbiotic, Prebiotics and Probiotics in Children With Cerebral Palsy and Constipation June 5, 2017 December 21, 2018
NCT03279341 Completed Phase 4 Effect of PEG, Bisacodyl and Prucalopride on Colonic Motility in Healthy Subjects December 3, 2012 March 2016
NCT03569527 Completed N/A Kiwifruit, Prunes, & Fiber for Abdominal and Bowel Symptoms in US Patients With Chronic Constipation June 11, 2018 October 10, 2019
NCT05548842 Completed N/A The Combined Seed Extracts of Cassia Obtusifolia Linne and Foeniculum Vulgare Mill in Patients With Chronic Constipation July 1, 2022 December 31, 2023
NCT05734859 Completed N/A Drinking Effect of Electrolyzed Alkaline Reduced Water on Functional Constipation November 30, 2022 January 13, 2023
NCT05980988 Completed N/A Effectiveness and Safety of Probiotic in Regulating Chronic Constipation September 9, 2021 April 6, 2023
NCT00730015 Completed Phase 3 Trial of Linaclotide in Patients With Chronic Constipation August 2008 October 2009
NCT00141089 Completed Phase 3 Assessment of Efficacy and Safety of Tegaserod in Male Patients With Chronic Constipation. March 2004 February 2005
NCT00745147 Completed Phase 3 Comparison of TCM and Laxatives for Adults With Chronic Constipation July 2008 April 2010
NCT00746200 Completed Phase 3 Acupuncture for Chronic Constipation October 2008 May 2010
NCT00765882 Completed Phase 3 Phase III, Randomized, Double-Blind, Placebo-Controlled, Trial of Linaclotide Administered to Patients With Chronic Constipation September 2008 August 2009
NCT00765999 Completed Phase 3 An Open-Label, Long-Term Safety Study of Linaclotide in Patients With Chronic Constipation or Irritable Bowel Syndrome With Constipation October 31, 2008 January 31, 2012
NCT00868985 Completed Phase 1 Effects of Oral PEG 3350 on Electrolyte Balance January 2008
NCT00872430 Completed Phase 2 Laxative Effectiveness of a Phytotherapeutic Tea July 2002 June 2003
NCT00906971 Completed N/A Physiotherapeutic Intervention in Children With Chronic Functional Constipation March 2009 April 2010
NCT00987844 Completed Phase 3 Study to Evaluate Long-Term Safety, Tolerability, and Satisfaction With Prucalopride in Chronic Constipation July 1998
NCT01007123 Completed Phase 2 Study of Elobixibat (A3309) in Patients With Chronic Idiopathic Constipation November 2009 October 2010
NCT01070615 Completed Phase 3 Study to Evaluate Long-Term Tolerability and Safety of Oral Prucalopride in Chronic Constipation June 1998
NCT01523184 Completed Phase 2 A Phase 2 Study to Evaluate Pharmacodynamics of YKP10811 in Patients With Chronic or Functional Constipation March 2012 November 2013
NCT06427863 Not yet recruiting N/A Effect of Antibiotic Pretreatment on the Efficacy of WMT in the Treatment of Chronic Constipation June 2024 December 31, 2029
NCT04784780 Recruiting Phase 4 Long-term Elobixibat for Chronic Constipation August 6, 2021 November 30, 2023
NCT03060330 Recruiting N/A Laparoscopic Ventral Mesh Rectopexy Combined With or Without Stapled Trans-anal Rectal Resection for Obstructed Defecation Syndrome April 26, 2017 April 2026
NCT04838522 Recruiting A Study of Prucalopride in Breastfeeding Women With Constipation March 2, 2022 December 31, 2026
NCT03819062 Recruiting N/A Sacral Neuromodulation as Treatment for Chronic Constipation September 8, 2019 February 1, 2027
NCT05723731 Recruiting N/A Effect of Transcutaneous Auricular Vagal Nerve Stimulation on Chronic Constipation January 3, 2023 February 28, 2024
NCT04869280 Recruiting Post-Marketing Study of Prucalopride Safety In Pregnancy May 21, 2021 May 31, 2026
NCT05192317 Recruiting N/A Administration of a Natural Molecular Complex in Functional Chronic Constipation November 9, 2021 September 30, 2023
NCT05703464 Terminated Phase 4 Elobixibat for Chronic Constipation Without Defecation Desire February 9, 2023 March 3, 2023
NCT00501241 Terminated Phase 2 Phase II, Randomized, Placebo-Controlled Study of ATI-7505 in Patients With Chronic Idiopathic Constipation July 2007 July 2008
NCT00348634 Terminated Phase 4 Effect of Tegaserod on Orocecal Transit in Elderly Chronic Constipation Patients July 2006 April 2007
NCT05165199 Unknown status Phase 4 Elobixibat for Chronic Constipation Without Defecation Desire March 1, 2022 March 2023
NCT03508076 Unknown status N/A Efficacy of Vibrating Capsule in Patients With Chronic Constipation February 1, 2017 June 30, 2018
NCT00861562 Unknown status Phase 3 Clinical Efficacy and Safety Evaluation of the Drug Imescard Compound Water Smartweed Pills April 2008 April 2009
NCT00671684 Unknown status Phase 1/Phase 2 Endoscopic Mucosal Resection (EMR) for Diagnosis of Hirschsprung's Disease October 2007 April 2009
NCT02433847 Unknown status Phase 4 Effect of Mosapride on Gut Transit in Patients With Chronic Constipation or Constipated Irritable Bowel Syndrome and Healthy Subjects May 2015 December 2016
NCT05202028 Unknown status N/A The Efficacy of Massage and Reflexology Applications in Children With Cerebral Palsy November 5, 2021 August 30, 2022
NCT01599156 Unknown status Phase 2 Reflexology for Chronic Constipation July 2012 April 2013
NCT01692132 Withdrawn A Post Marketing Surveillance Study on the Safety and Effectiveness of Prucalopride in the Treatment of Chronic Constipation February 2013 December 2014
HPO Human Phenotype ID (Human Phenotype Ontology)
HP:0012450