Limbal stem cell deficiency
Information
- Disease name
- Limbal stem cell deficiency
- Disease ID
- Description
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
| Genes | Mutation | Description | Source | Links |
|---|
| NCT ID | Status | Phase | Summary | Start date | Completion date |
|---|---|---|---|---|---|
| NCT03549299 | Active, not recruiting | Phase 1/Phase 2 | Allogeneic ABCB5-positive Limbal Stem Cells for Treatment of LSCD | July 4, 2019 | September 2023 |
| NCT02149732 | Available | Clinical Trial on the Effect of Autologous Oral Mucosal Epithelial Sheet Transplantation | May 2014 | December 2016 | |
| NCT00736307 | Completed | Phase 1/Phase 2 | Autologous Transplantation of Cultivated Limbal Stem Cells on Amniotic Membrane in Limbal Stem Cell Deficiency (LSD) Patients | October 2007 | October 2009 |
| NCT02568527 | Completed | N/A | Biodegradable Synthetic Scaffold as a Substitute for hAM in Limbal Epithelial Cells Transplant in LSCD Patients | October 2015 | July 2018 |
| NCT02592330 | Completed | Phase 1/Phase 2 | Limbal Stem Cell Deficiency (LSCD) Treatment With Cultivated Stem Cell (CALEC) Graft | August 1, 2016 | March 31, 2023 |
| NCT03217435 | Completed | N/A | Corneal Epithelial Allograft From Living-related Donor for LSCD | July 27, 2017 | November 13, 2019 |
| NCT06265298 | Not yet recruiting | N/A | Implementation of a Protocol for the Transdifferentiation of Buccal Mucosal Epithelium Into Corneal Epithelium | February 2024 | February 2025 |
| NCT06412718 | Not yet recruiting | Validation of Human Drugs Target of Repurposed Drugs and Novel Therapies | May 2024 | April 2026 | |
| NCT03943797 | Recruiting | Phase 1 | Cultivated Autologous Oral Mucosal Epithelial Transplantation | March 1, 2016 | December 31, 2024 |
| NCT01756365 | Recruiting | N/A | Autologous Cultured Corneal Epithelium (CECA) for the Treatment of Limbal Stem Cell Deficiency | December 2012 | December 2027 |
| NCT06452316 | Recruiting | Phase 1 | Study to Evaluate the Safety and Efficacy of CSB-001 Ophthalmic Solution 0.1% in Subjects With Limbal Stem Cell Deficiency | May 15, 2024 | August 2025 |
| NCT02579993 | Terminated | N/A | ABCB5 as a Prognostic Marker in Survival of Cultivated Limbal Stem Cell Transplantation | March 2015 | March 2018 |
| NCT02318485 | Unknown status | Phase 2 | Limbal Epithelial Stem Cell Transplantation: a Phase II Multicenter Trial | April 2015 | December 2020 |
| NCT03015779 | Unknown status | Phase 1/Phase 2 | Transplantation of Autologous Oral Mucosal Epithelial Stem Cell Sheet for Treating Limbal Stem Cell Deficiency Disease | January 2017 | December 2018 |
| NCT03217487 | Unknown status | N/A | Corneal Epithelial Autograft for LSCD | July 25, 2017 | December 30, 2019 |
| NCT00845117 | Unknown status | Phase 1/Phase 2 | Cultivated Stem Cell Transplantation for the Treatment of Limbal Stem Cell Deficiency | July 2008 | June 2014 |
| NCT01489501 | Withdrawn | Phase 3 | Multicenter Study of CAOMECS Transplantation to Patients With Total Limbal Stem Cell Deficiency |
- MedGen concept unique identifier (MedGen Concept name)
- C1561989
- MedGen unique identifier (MedGen Concept name)
- 295775