Drug Resistant Epilepsy

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Information
Disease name
Drug Resistant Epilepsy
Disease ID
Description
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
Genes Mutation Description Source Links
NCT ID Status Phase Summary Start date Completion date
NCT03529045 Active, not recruiting Registry of Subjects With Drug Resistant Epilepsy and Treated With the VNS Therapy System. February 5, 2018 April 30, 2025
NCT04457687 Available Extended Access Program With Lorcaserin For The Treatment of Dravet Syndrome and Other Refractory Epilepsies
NCT03676049 Available Cannabidiol for Drug Resistant Pediatric Epilepsy (Expanded Access Use)
NCT05809349 Completed N/A The Mechanism of cTBS Targeting Dentate Nucleus for DRE April 1, 2023 December 31, 2023
NCT03419000 Completed N/A Circulating microRNAs as Biomarkers of RESPIratory Dysfunction in Patients With Refractory epilePSY March 16, 2018 March 31, 2022
NCT03443388 Completed N/A Novel Helmet Design in Patients With Seizures August 14, 2017 March 20, 2020
NCT04378075 Completed Phase 2/Phase 3 A Study to Evaluate Efficacy and Safety of Vatiquinone for Treating Mitochondrial Disease in Participants With Refractory Epilepsy September 28, 2020 December 27, 2023
NCT06432231 Completed N/A Effects of Low Glycemic Index Diet in Children With Drug-resistant Epilepsy August 28, 2022 February 20, 2024
NCT03860298 Completed N/A Safety of Using NaviFUS System in Patients With Drug Resistant Epilepsy June 17, 2019 October 14, 2020
NCT02982824 Completed N/A Effect of Magnesium Supplementation for Children With Drug Resistant Idiopathic Epilepsy September 2016 March 2017
NCT05697887 Completed N/A Feasibility, Tolerability and Efficacy of the Ketogenic Diet in Children With Drug-resistant Epilepsy in South Vietnam June 1, 2019 October 31, 2021
NCT06341075 Enrolling by invitation N/A Real-World Study of Magnetic Resonance-guided Laser Interstitial Thermal Therapy for Drug-resistant Epilepsy March 14, 2024 March 14, 2026
NCT03014440 No longer available Study of Cannabidiol for Drug-Resistant Epilepsies
NCT06334952 Not yet recruiting N/A Efficacy of Personnalized Transcranial Direct Current Electrical Stimulation (tDCS) in Drug-resistant Epileptic June 1, 2024 April 30, 2027
NCT06387186 Not yet recruiting Phase 1 Leucine Enriched Essential Amino Acid Powder as an Add-on to a Classic Ketogenic Diet in Refractory Epilepsy April 2024 March 31, 2025
NCT06366009 Not yet recruiting Assessment of Patients With Drug-resistant Temporal Lobe Epilepsy With EEG Extended With Intra-auricular Electrodes April 8, 2024 July 31, 2024
NCT05527093 Not yet recruiting N/A Cartography of Social Cognition Network and Their Alterations in Patients With Epilepsy March 1, 2024 January 1, 2028
NCT05555537 Not yet recruiting MiRNA223 and HMGB1 as Apredictos for Drug Resistant Epilepsy November 1, 2022 November 1, 2024
NCT04601974 Not yet recruiting Phase 1/Phase 2 Lentiviral Gene Therapy for Epilepsy September 2024 September 2032
NCT06340802 Not yet recruiting N/A A First in hUman Study for Resistant Epilepsy With the Vagus Nerve stimulatiOn Device by syneRgia medicAl June 2024 December 2026
NCT04935567 Not yet recruiting N/A PRediction of Vagal Nerve Stimulation EfficaCy In Drug-reSistant Epilepsy December 1, 2021 December 31, 2026
NCT06388707 Not yet recruiting Phase 1/Phase 2 A Safety, Tolerability, and Preliminary Efficacy of Low-intensity Focused Ultrasound Neuromodulation in Patients With Drug-resistant Epilepsy August 1, 2024 December 31, 2025
NCT06292494 Recruiting N/A Focused Ultrasound for Drug-resistant Epilepsy January 1, 2024 December 31, 2027
NCT06309251 Recruiting Effectiveness and Impact on the Quality of Life of Ketogenic Diet in Pediatric Patients March 1, 2022 May 31, 2026
NCT06432907 Recruiting N/A StereoEEG Motor Neuronal Potentials Decoding June 6, 2024 December 25, 2026
NCT03268824 Recruiting Impact of Epileptic Discharge on the Structural Connectivity of the Developing Brain December 19, 2017 October 2024
NCT03868293 Recruiting N/A Low Intensity Focused Ultrasound Epilepsy: A Pilot Trial February 7, 2019 November 9, 2025
NCT04126369 Recruiting N/A Impact of Mindfulness Intervention on Quality of Life in Patients With Drug-resistant Epilepsy. January 20, 2020 September 20, 2027
NCT04714996 Recruiting Phase 2 Efficacy, Safety and Pharmacokinetics of ES-481 in Adult Patients With Drug Resistant Epilepsy October 30, 2020 December 2023
NCT04839601 Recruiting N/A RNS System RESPONSE Study October 27, 2021 December 31, 2027
NCT04999046 Recruiting N/A NaviFUS™ System Neuromodulating Treatment for Patients With Drug Resistant Epilepsy September 1, 2021 June 2024
NCT05019885 Recruiting Phase 2 The Efficacy of a Subanesthetic Doses of IV Ketamine in the Treatment Drug Resistant Epilepsy August 26, 2022 July 2024
NCT05234411 Recruiting Ketonemia Through Menstrual Cycle July 1, 2020 December 31, 2023
NCT05393518 Recruiting N/A Electroclinical Correlation of Anxiety October 11, 2022 October 11, 2024
NCT05459090 Recruiting Functional Study of Inhibitory Neurotransmission in the Human Epileptic Brain. July 29, 2022 July 31, 2027
NCT05485558 Recruiting Phase 2 the Safety and Efficacy of N-acetyl Cysteine in Children With Drug-Resistant Epilepsy September 15, 2022 May 1, 2026
NCT05539287 Recruiting Phase 2 Clinical Study Evaluating the Safety of Lactobacillus Probiotic in Children With Drug Resistant Epilepsy September 25, 2022 January 2025
NCT05670847 Recruiting Phase 2/Phase 3 Exogenous Ketone Esters for Drug Resistant Epilepsy January 10, 2023 July 1, 2024
NCT05697614 Recruiting Phase 4 The Benefit and Safety of Older Generation Anti-Epileptic Drugs (AEDs) in Drug-Resistant Epilepsy Children March 1, 2023 June 30, 2023
NCT05928598 Recruiting N/A Goals for Epilepsy Clinic Visits Trial September 27, 2023 January 1, 2027
NCT05947656 Recruiting N/A Evaluation of the NaviFUS System in Drug Resistant Epilepsy October 2, 2023 May 2025
NCT05951244 Recruiting N/A Cathodal Transcranial Direct Current Stimulation in Patients With Drug-resistant Focal Epilepsy April 3, 2023 April 2025
NCT05997758 Recruiting Investigating Surprise Signals in the Anterior Insula January 15, 2024 December 2025
NCT06053281 Recruiting Early Phase 1 The Role of Vitamin D in Neuroinflammatory on Drug Resistant Epilepsy January 19, 2024 July 1, 2025
NCT06059157 Recruiting N/A Epileptogenic Network Visualisation With Advanced MRI October 25, 2023 October 2029
NCT06075485 Recruiting Management of Drug-resistant Epilepsy in Infants and Children: a Real-life Study of the Use of the Ketogenic Diet in France and the KetoCal® Range in Its Maintenance January 15, 2024 June 2026
NCT03808935 Terminated Phase 3 Cannabis Extract in Refractory Epilepsy Study January 10, 2019 March 15, 2020
NCT04553354 Unknown status Cortical Resections in Drug Resistant Epilepsy September 10, 2020 November 10, 2022
NCT04705298 Unknown status Phase 4 Role of the Gut Microbiota in Pediatric Epilepsy June 1, 2021 September 1, 2022
NCT03475225 Unknown status Phase 3 Vitamine D in Drug Resistant Epilepsy April 2018 April 2020
NCT03464487 Unknown status N/A Comparison Between Efficacy of Daily and Intermittent Low Glycemic Index Therapy Diet February 15, 2018 January 2019
NCT02708030 Unknown status N/A Dietary Therapy In Epilepsy Treatment (DIET-Trial): A Randomised Non Inferiority Trial Comparing KD, MAD & LGIT for Drug Resistant Epilepsy April 2016 September 2017
NCT03764956 Unknown status Phase 4 Comparison of Efficacy of LGIT and MAD Among Children With Drug Resistant Epilepsy December 26, 2018 December 2019
MeSH unique ID (MeSH (Medical Subject Headings))
D000069279