neonatal abstinence syndrome
Information
- Disease name
- neonatal abstinence syndrome
- Disease ID
- DOID:9828
- Description
- "A withdrawal disorder that is characterized by a group of problems that occur in a newborn who was exposed to addictive illegal or prescription drugs while in the mother's womb or postnatally following the discontinuance of drug treatment." [url:http\://en.wikipedia.org/wiki/Neonatal_abstinence_syndrome]
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
| Genes | Mutation | Description | Source | Links |
|---|
| NCT ID | Status | Phase | Summary | Start date | Completion date |
|---|---|---|---|---|---|
| NCT03725332 | Active, not recruiting | N/A | The PATH Home Trial: A Comparative Effectiveness Study of Peripartum Opioid Use Disorder in Rural Kentucky | March 13, 2019 | April 2024 |
| NCT03918850 | Active, not recruiting | Phase 3 | Medication Treatment for Opioid Use Disorder in Expectant Mothers | July 21, 2020 | January 31, 2025 |
| NCT03911466 | Active, not recruiting | Phase 3 | Medication Treatment for Opioid Use Disorder in Expectant Mothers: Conceptual Model Assessments Sub-study | July 21, 2020 | January 31, 2025 |
| NCT03396588 | Active, not recruiting | Phase 3 | Non-Opiate Treatment After Prenatal Opiate Exposure to Prevent Postnatal Injury to the Young Brain | December 7, 2017 | March 1, 2025 |
| NCT01561079 | Completed | Phase 2/Phase 3 | Fetal and Infant Effects of Maternal Buprenorphine Treatment | February 2012 | June 2016 |
| NCT01671410 | Completed | Phase 1 | Buprenorphine for Treatment of Neonatal Abstinence Syndrome in Infants With In Utero Exposure to Benzodiazepines | August 2012 | September 2016 |
| NCT01708707 | Completed | Phase 2 | Comparison of Buprenorphine to Morphine in Treatment of Neonatal Abstinence Syndrome (NAS) | December 2012 | October 31, 2017 |
| NCT01723722 | Completed | Phase 4 | Treatment of Neonatal Abstinence Syndrome | January 2007 | September 2009 |
| NCT01734551 | Completed | Phase 4 | NAS Treatment - Opiate Versus Non-Opiate | September 2011 | December 2014 |
| NCT01754324 | Completed | The Pharmacokinetics of Oral Methadone in the Treatment of Neonatal Abstinence Syndrome | December 2012 | December 2013 | |
| NCT01804075 | Completed | Phase 4 | Comparison Between Methadone and Morphine for Neonatal Opiate Withdrawal | January 2011 | October 2012 |
| NCT01889121 | Completed | Utility of Psychosocial Intervention in Improving Outcome for Methadone-exposed Infants and Their Mothers | February 2013 | May 2013 | |
| NCT01958476 | Completed | Phase 3 | Improving Outcomes in Neonatal Abstinence Syndrome | September 2013 | August 30, 2018 |
| NCT01965704 | Completed | Phase 2 | Can Ondansetron Prevent Neonatal Abstinence Syndrome (NAS) in Babies Born to Narcotic-dependent Women | September 9, 2014 | September 16, 2020 |
| NCT02062151 | Completed | N/A | Acupuncture in Neonatal Abstinence Syndrome (NAS) Babies | February 2014 | October 2015 |
| NCT02178189 | Completed | Phase 2 | RCT of High- vs. Standard-Calorie Formula for Methadone-Exposed Infants | April 2010 | December 2013 |
| NCT02182973 | Completed | Donor Human Milk in Neonatal Abstinence Syndrome | June 2014 | September 9, 2017 | |
| NCT02334111 | Completed | N/A | RESPECT-PLUS: Services for Infants With Prenatal Opiate Exposure | July 2013 | September 2016 |
| NCT02768844 | Completed | N/A | Physiology and Therapeutic Management of Neonatal Abstinence Syndrome | April 2011 | December 15, 2019 |
| NCT02797990 | Completed | Conflict Between Maternal Autonomy and Child Health in Substance-use | May 2016 | September 2016 | |
| NCT02801331 | Completed | N/A | Efficacy and Outcomes of a Non-Pharmacological Intervention for Neonatal Abstinence Syndrome | March 9, 2017 | June 6, 2021 |
| NCT02810782 | Completed | Phase 3 | How to Treat Opiate Withdrawal in Neonates | June 2001 | December 2007 |
| NCT02851303 | Completed | Phase 4 | Morphine Versus Methadone for Opiate Exposed Infants With Neonatal Abstinence Syndrome | October 2016 | September 30, 2018 |
| NCT02872077 | Completed | N/A | Efficacy of Auricular Acupuncture on Neonatal Abstinence Syndrome | August 2016 | October 9, 2018 |
| NCT03028883 | Completed | Buprenorphine Dose Adjustments and Gestational Age | December 2, 2016 | December 22, 2016 | |
| NCT03097484 | Completed | Phase 3 | The Effect of Aromatherapy on Neonatal Abstinence Syndrome and Salivary Cortisol Levels | July 25, 2015 | April 30, 2017 |
| NCT03113656 | Completed | N/A | Weighted Blankets With Infants With NAS | July 14, 2017 | January 18, 2018 |
| NCT03973801 | Completed | N/A | Feasibility of Auricular Acupressure as an Adjunct Treatment for Neonatal Abstinence Syndrome (NAS) | August 19, 2019 | September 16, 2019 |
| NCT00510016 | Completed | Phase 2 | Clonidine as Adjunct Therapy for the Treatment of Neonatal Abstinence Syndrome | July 2002 | December 2005 |
| NCT00521248 | Completed | Phase 1 | Buprenorphine for the Treatment of Neonatal Abstinence Syndrome | April 2004 | January 2010 |
| NCT01452789 | Completed | Phase 3 | Blinded Trial of Buprenorphine or Morphine in the Treatment of the Neonatal Abstinence Syndrome | November 2011 | June 2016 |
| NCT03334981 | Completed | Interest of Concentrations in Meconium of Buprenorphine and Methadone as a Prognostic Factor of NAS Outcome | July 2012 | July 2015 | |
| NCT03549936 | Completed | N/A | Role of Low Lactose Infant Formula In The Management of Neonatal Abstinence Syndrome | July 9, 2014 | June 30, 2018 |
| NCT03567603 | Completed | Sound Processing Changes in Babies With Opioid Exposure | March 25, 2019 | June 30, 2023 | |
| NCT03608696 | Completed | Phase 1/Phase 2 | Buprenorphine Pharmacometric Open Label Research Study of Drug Exposure | August 29, 2018 | July 11, 2019 |
| NCT03670160 | Completed | Phase 2 | Clonidine Versus Phenobarbital as Adjunctive Therapy for Neonatal Abstinence Syndrome | October 1, 2018 | May 31, 2020 |
| NCT03890562 | Completed | N/A | Assessing the Effects of Auricular Acupressure on Newborns With NAS | September 4, 2019 | March 5, 2021 |
| NCT00496951 | Completed | Vagal Tone and Neonatal Abstinence Syndrome | September 2006 | September 2008 | |
| NCT04049799 | Completed | Maternal Opioid Treatment: Human Experimental Research - Data Yield Appropriate Decisions | August 8, 2019 | February 1, 2024 | |
| NCT04298853 | Completed | Phase 4 | Optimal Morphine Dosing Schedule for Neonatal Abstinence Syndrome | June 30, 2020 | October 1, 2021 |
| NCT04588519 | Completed | N/A | tAN to Mitigate Withdrawal Behaviors in Neonates | May 30, 2020 | December 30, 2020 |
| NCT04783558 | Not yet recruiting | N/A | Effective Caregiving for Neonatal Abstinence Syndrome: Testing an Instructional Mobile Technology Platform for High-Risk Pregnant Women | June 1, 2024 | June 30, 2025 |
| NCT03092011 | Recruiting | Phase 4 | Treatment of Neonatal Abstinence Syndrome With Clonidine Versus Morphine as Primary Therapy | February 21, 2018 | December 2026 |
| NCT04508348 | Recruiting | N/A | Clinical Trial to Decrease Length of Stay in Infants With Neonatal Abstinence Syndrome With an Exclusive Human Milk Diet | August 31, 2020 | August 2027 |
| NCT06303986 | Recruiting | Study to Collect Data for Neonatal Abstinence Syndrome (NAS) and Evaluate the Automated Data Collection Process | March 18, 2024 | June 30, 2024 | |
| NCT05129020 | Recruiting | N/A | Neurostimulation to Improve NOWS Outcomes | July 26, 2022 | November 2027 |
| NCT03718104 | Recruiting | MOM NEST Study: Maternal Opioid Medication: Naltrexone Efficacy Study | December 1, 2018 | September 2024 | |
| NCT03987165 | Recruiting | N/A | The Effect of Music Therapy on Newborns | December 10, 2018 | May 31, 2024 |
| NCT05226624 | Recruiting | N/A | The Alberta Neonatal Abstinence Syndrome Mother-Baby Care ImprovEmeNT Program | October 1, 2023 | June 30, 2025 |
| NCT05937594 | Recruiting | MicroRNA Biomarkers for Neonatal Opioid Withdrawal Syndrome | January 15, 2020 | April 10, 2025 | |
| NCT04419857 | Recruiting | N/A | A Trial to Determine Weight Gain Benefits of Caloric Supplementation for NAS Infants | December 4, 2020 | May 2026 |
| NCT03911739 | Recruiting | Phase 3 | Medication Treatment for Opioid Use Disorder in Expectant Mothers: Infant Neurodevelopmental Outcomes Sub-study | June 14, 2021 | January 31, 2025 |
| NCT03762317 | Terminated | Phase 4 | Clonidine as Adjunct to Morphine for Neonatal Abstinence Syndrome | April 30, 2018 | December 12, 2018 |
| NCT01360450 | Terminated | Phase 2/Phase 3 | Clonidine to Treat Iatrogenic-induced Opioid Dependence in Infants | July 2011 | December 2014 |
| NCT01175668 | Terminated | N/A | Clonidine for Neonatal Abstinence Syndrome Study | July 2010 | October 2012 |
| NCT03246243 | Terminated | Quantitative Assessment of Sucking for Early Diagnosis of Brain Injury in Infants at High Risk | March 29, 2017 | May 18, 2021 | |
| NCT03134703 | Terminated | Phase 2 | Methadone Demonstration Project With Neonatal Intensive Care Unit Infants Diagnosed With Neonatal Abstinence Syndrome | February 27, 2017 | March 27, 2019 |
| NCT03881553 | Terminated | N/A | Interventions to Help Infants Recover in the Hospital | July 19, 2019 | December 31, 2020 |
| NCT03977545 | Unknown status | N/A | Actigraphy and Neonatal Abstinence Syndrome | January 23, 2019 | December 31, 2021 |
| NCT04983563 | Unknown status | N/A | Actigraphy and Neonatal Abstinence Syndrome of Hospitalized Newborn in Intensive Care Units | March 1, 2021 | December 31, 2022 |
| NCT04611659 | Unknown status | N/A | Averting NAS Among Opioid-Using Young Women Receiving MAT Using Buprenorphine | November 2020 | October 31, 2021 |
- Disase is a (Disease Ontology)
- DOID:0060001
- Cross Reference ID (Disease Ontology)
- ICD10CM:P96.1
- Cross Reference ID (Disease Ontology)
- ICD9CM:779.5
- Cross Reference ID (Disease Ontology)
- MESH:D009357
- Cross Reference ID (Disease Ontology)
- NCI:C35808
- Cross Reference ID (Disease Ontology)
- NCI:C87101
- Cross Reference ID (Disease Ontology)
- SNOMEDCT_US_2023_03_01:414819007
- Cross Reference ID (Disease Ontology)
- UMLS_CUI:C0027609
- Cross Reference ID (Disease Ontology)
- UMLS_CUI:C1332133
- Exact Synonym (Disease Ontology)
- Drug withdrawal syndrome in newborn
- MeSH unique ID (MeSH (Medical Subject Headings))
- D009357