choroideremia
Information
- Disease name
- choroideremia
- Disease ID
- DOID:9821
- Description
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
| Genes | Mutation | Description | Source | Links |
|---|
| NCT ID | Status | Phase | Summary | Start date | Completion date |
|---|---|---|---|---|---|
| NCT04483440 | Active, not recruiting | Phase 1 | Dose Escalation Study of Intravitreal 4D-110 in Patients With Choroideremia | June 2, 2020 | June 2027 |
| NCT01603576 | Completed | N/A | Pilot Study of a Suprachoroidal Retinal Prosthesis | May 2012 | August 2014 |
| NCT01461213 | Completed | Phase 1/Phase 2 | Gene Therapy for Blindness Caused by Choroideremia | October 2011 | October 2017 |
| NCT01864486 | Completed | N/A | Restoring Vision With the Intelligent Retinal Implant System (IRIS V1)in Patients With Retinal Dystrophy | April 2013 | October 13, 2017 |
| NCT04795206 | Completed | Natural Disease Progression in Participants With Choroideremia | August 26, 2020 | August 10, 2021 | |
| NCT02671539 | Completed | Phase 2 | THOR - Tübingen Choroideremia Gene Therapy Trial | January 2016 | February 2018 |
| NCT03359551 | Completed | Natural History of the Progression of Choroideremia Study | June 30, 2015 | October 1, 2020 | |
| NCT03406416 | Completed | N/A | Study of a Suprachoroidal Retinal Prosthesis | February 13, 2018 | December 18, 2020 |
| NCT03496012 | Completed | Phase 3 | Efficacy and Safety of BIIB111 for the Treatment of Choroideremia | December 11, 2017 | December 1, 2020 |
| NCT03507686 | Completed | Phase 2 | A Safety Study of Retinal Gene Therapy for Choroideremia With Administration of BIIB111 | November 29, 2017 | June 29, 2022 |
| NCT04750785 | Completed | A Study to Assess Choroideremia (CHM) Health Outcomes | December 15, 2020 | September 27, 2021 | |
| NCT02077361 | Completed | Phase 1/Phase 2 | An Open Label Clinical Trial of Retinal Gene Therapy for Choroideremia | April 2015 | May 16, 2022 |
| NCT02341807 | Completed | Phase 1/Phase 2 | Safety and Dose-escalation Study of AAV2-hCHM in Participants With CHM (Choroideremia) Gene Mutations | January 15, 2015 | October 12, 2022 |
| NCT02407678 | Completed | Phase 2 | REP1 Gene Replacement Therapy for Choroideremia | August 16, 2016 | July 23, 2021 |
| NCT02553135 | Completed | Phase 2 | Choroideremia Gene Therapy Clinical Trial | September 2015 | February 2018 |
| NCT02670980 | Completed | N/A | Compensation for Blindness With the Intelligent Retinal Implant System (IRIS V2) in Patients With Retinal Dystrophy | January 2016 | May 2019 |
| NCT03584165 | Enrolling by invitation | Phase 3 | Long-term Safety and Efficacy Follow-up of BIIB111 for the Treatment of Choroideremia and BIIB112 for the Treatment of X-Linked Retinitis Pigmentosa | June 4, 2018 | June 4, 2026 |
| NCT05158049 | Enrolling by invitation | Longitudinal Study of a Bionic Eye | December 9, 2021 | December 9, 2026 | |
| NCT01866371 | Recruiting | High Resolution Retinal Imaging | May 2013 | December 2027 | |
| NCT05282953 | Recruiting | Phase 1/Phase 2 | A Phase I/II Dose-escalating Study of the Safety, Tolerability and Efficacy of KIO-301 Administered Intravitreally to Patients With Retinitis Pigmentosa and Choroideremia (ABACUS) | November 10, 2022 | January 2025 |
| NCT02435940 | Recruiting | Inherited Retinal Degenerative Disease Registry | June 2014 | June 2037 | |
| NCT05258032 | Recruiting | Structural and Functional Characterization of Rare Ocular Diseases | November 24, 2021 | November 24, 2025 | |
| NCT02994368 | Terminated | "Natural History" Study of Choroideremia | December 2016 | October 2021 | |
| NCT01654562 | Terminated | Phase 1/Phase 2 | The Short-term Effects of Simvastatin on the Vision of Males Affected by Choroideremia | December 2012 | July 2013 |
| NCT00427180 | Unknown status | N/A | IRIS PILOT - Extended Pilot Study With a Retinal Implant System | December 2006 | December 2010 |
| NCT05045703 | Withdrawn | N/A | The Dark-Adapted Retinal Function Response in Choroideremia (DARC) Study | May 2023 | May 2024 |
- Disase is a (Disease Ontology)
- DOID:1417
- Cross Reference ID (Disease Ontology)
- GARD:6061
- Cross Reference ID (Disease Ontology)
- ICD10CM:H31.21
- Cross Reference ID (Disease Ontology)
- ICD9CM:363.55
- Cross Reference ID (Disease Ontology)
- MESH:D015794
- Cross Reference ID (Disease Ontology)
- MIM:303100
- Cross Reference ID (Disease Ontology)
- NCI:C34469
- Cross Reference ID (Disease Ontology)
- ORDO:180
- Cross Reference ID (Disease Ontology)
- SNOMEDCT_US_2023_03_01:75241009
- Cross Reference ID (Disease Ontology)
- UMLS_CUI:C0008525
- Exact Synonym (Disease Ontology)
- progressive Choroidal Atrophy
- HPO Human Phenotype ID (Human Phenotype Ontology)
- HP:0001139
- OrphaNumber from OrphaNet (Orphanet)
- 180
- MeSH unique ID (MeSH (Medical Subject Headings))
- D015794