pyoderma gangrenosum

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Information
Disease name
pyoderma gangrenosum
Disease ID
DOID:8553
Description
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
Genes Mutation Description Source Links
NCT ID Status Phase Summary Start date Completion date
NCT03311464 Completed Phase 3 A Study Assessing the Efficacy and Safety of Adalimumab in Active Ulcer(s) of Pyoderma Gangrenosum in Participants in Japan October 27, 2017 April 21, 2020
NCT03971643 Completed Phase 2 Exploratory Study of IFX-1 in Patients With Pyoderma Gangrenosum May 16, 2019 January 3, 2022
NCT02733094 Completed Phase 1/Phase 2 Single-arm Study to Assess a Potential Effect of Anti-IL-17 (Secukinumab) in the Treatment of Pyoderma Gangrenosum April 2016 September 19, 2019
NCT03137160 Completed Phase 2 An Open-Label, Proof-of-Concept Study of Ixekizumab in the Treatment of Pyoderma Gangrenosum May 4, 2017 August 16, 2018
NCT00791557 Completed N/A Open Label Study for Adults With Pyoderma Gangrenosum and Inflammatory Bowel Disease October 2008 February 2010
NCT01302795 Completed Phase 2 Canakinumab for Pyoderma Gangrenosum February 2011 November 2015
NCT01882504 Completed Phase 2 Proof of Concept Study of Gevokizumab in the Treatment of Pyoderma Gangrenosum May 2013 October 2015
NCT01965613 Completed Phase 2 A Phase II Open Label Study of Xilonix in Subjects With Pyoderma Gangrenosum January 31, 2014 December 31, 2016
NCT04895566 Completed Early Phase 1 Phase 0/1 Local Application of the Monoclonal Antibody (Mab) sB24M in Patients With Purulent Pyoderma May 24, 2021 March 16, 2023
NCT05984654 Not yet recruiting N/A Autologous Platelet-Rich Plasma Therapy in the Treatment of Pyoderma Gangrenosum May 28, 2024 June 30, 2025
NCT05343754 Not yet recruiting Phase 3 Hyperbaric Oxygen Therapy for Pyoderma Gangrenosum August 2022 December 2026
NCT05821374 Not yet recruiting Early Phase 1 Deucravacitinib in PG March 2025 January 2026
NCT06092216 Recruiting Phase 2 Spesolimab in Pyoderma Gangrenosum September 26, 2023 September 2025
NCT04750213 Recruiting A Study to Assess Adverse Events and Change in Disease State in Adult Participants Being Treated With Humira in Participants Diagnosed With Pyoderma Gangrenosum (PG) February 12, 2021 August 31, 2025
NCT04901325 Recruiting Phase 2 Baricitinib in the Treatment of Adults With Pyoderma Gangrenosum (PG) October 2023 May 31, 2025
NCT05120726 Recruiting Phase 4 A Novel Therapeutic Treatment of Pyoderma Gangrenosum June 2, 2021 May 1, 2026
NCT05964413 Recruiting Phase 3 Phase III Trial to Investigate Efficacy and Safety of Vilobelimab in Ulcerative Pyoderma Gangrenosum August 15, 2023 May 15, 2026
NCT03072953 Terminated Phase 2 Efficacy and Safety of APD334 in Patients With Pyoderma Gangrenosum June 7, 2017 May 22, 2018
NCT02315417 Terminated Phase 3 An Efficacy and Safety Study of Gevokizumab in Treating Active Ulcers of Pyoderma Gangrenosum November 2014 March 2016
NCT02318914 Terminated Phase 3 A 2-Year, Open-Label, Safety Extension Study of Gevokizumab in Subjects With Pyoderma Gangrenosum November 2014 February 2016
NCT02326740 Terminated Phase 3 An Efficacy and Safety Study of Gevokizumab in Treating Active Ulcers of Pyoderma Gangrenosum December 2014 March 2016
NCT01952275 Unknown status Observational Study of the Genetic Architecture of Neutrophil-Mediated Inflammatory Skin Diseases January 2014 January 2020
NCT04792957 Unknown status JAK-STAT Signaling Pathway in Pyoderma Gangrenosum May 1, 2022 July 31, 2022
NCT03636737 Unknown status Study on the Clinical Features, Comorbidities and Pathologies Associated With Pyoderma Gangrenosum December 2018 December 2019
NCT04274166 Withdrawn Phase 2 Secukinumab for the Inflammatory Phase of Pyoderma Gangrenosum May 2021 April 2022
NCT00690846 Withdrawn Phase 2 Study to Determine the Safety and Efficacy of Adalimumab in the Treatment of Pyoderma Gangrenosum July 2007 July 2007
NCT00730717 Withdrawn Phase 2 Safety and Efficacy Study of Humira in Treatment of Pyoderma Gangrenosum May 2009 December 2010
Disase is a (Disease Ontology)
DOID:4223
Cross Reference ID (Disease Ontology)
GARD:7510
Cross Reference ID (Disease Ontology)
ICD10CM:L88
Cross Reference ID (Disease Ontology)
ICD9CM:686.01
Cross Reference ID (Disease Ontology)
MESH:D017511
Cross Reference ID (Disease Ontology)
SNOMEDCT_US_2023_03_01:74578003
Cross Reference ID (Disease Ontology)
UMLS_CUI:C0085652
HPO Human Phenotype ID (Human Phenotype Ontology)
HP:0025452
OrphaNumber from OrphaNet (Orphanet)
48104
MedGen concept unique identifier (MedGen Concept name)
C0085652
MedGen unique identifier (MedGen Concept name)
43224
ICD10 preferred id (Insert disease from ICD10)
D0009964
ICD10 class code (Insert disease from ICD10)
L88
MeSH unique ID (MeSH (Medical Subject Headings))
D017511