varicose veins
Information
- Disease name
- varicose veins
- Disease ID
- DOID:799
- Description
- "A vein disease that is characterized by swollen, twisted veins visible just under the surface of the skin." [url:http\://www.nlm.nih.gov/medlineplus/varicoseveins.html, url:https\://www.nhlbi.nih.gov/health/health-topics/topics/vv/]
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
| NCT ID | Status | Phase | Summary | Start date | Completion date |
|---|---|---|---|---|---|
| NCT05410912 | Active, not recruiting | Varicose Vein in Patients Under the Age of 40 | January 1, 2021 | December 30, 2023 | |
| NCT02397226 | Active, not recruiting | N/A | Lower Limb Venous Insufficiency and the Effect of Radiofrequency Treatment Versus Open Surgery | September 1, 2014 | December 31, 2026 |
| NCT00841178 | Active, not recruiting | N/A | Endovenous Laser Therapy (EVLT) for Sapheno-Popliteal Incompetence and Short Saphenous Vein (SSV) Reflux: A RCT | October 2005 | November 2022 |
| NCT05707169 | Active, not recruiting | N/A | Comparison of Zero- and Two-centimeter Distance From Sapheno-femoral Junction in Laser Ablation of Varicose Vein | January 4, 2023 | May 4, 2024 |
| NCT06456125 | Active, not recruiting | N/A | Safety and Efficacy Of Amber Peripheral Liquid Embolic System | June 12, 2024 | December 2026 |
| NCT04034329 | Active, not recruiting | PREservation Versus Thermal Ablation | January 1, 2013 | February 1, 2025 | |
| NCT00759434 | Completed | N/A | A New Method of Surgically Treating Varicose Veins and Venous Ulcers - a Study to Assess Clinical and Economic Value | March 2004 | August 2009 |
| NCT00928421 | Completed | Phase 2 | An Open-label, Single-dose Pilot Study to Evaluate Varisolve® (Polidocanol Endovenous Microfoam (PEM)) 0.125% [0.2%] for Varicose Veins | June 2009 | January 2010 |
| NCT00954980 | Completed | Evaluation of Endovenous Sclerotherapy for Treatment of Varicose Veins | May 2009 | July 2016 | |
| NCT00991497 | Completed | N/A | A Trial to Compare the Outcome of Localised Varicosity Compression for 24 Hours and 5 Days After Foam Sclerotherapy to Truncal Varices | January 2007 | January 2008 |
| NCT01072877 | Completed | Phase 3 | Efficacy and Safety Study of Polidocanol Injectable Foam for the Treatment of Saphenofemoral Junction (SFJ) Incompetence | December 2010 | November 2012 |
| NCT01195623 | Completed | N/A | The Long-term Value of Preoperative Duplex Before Surgery for Varicose Veins | November 1997 | August 2010 |
| NCT01200199 | Completed | Validity of Electronic Diary for Monitoring Varicose Veins Symptoms | November 2010 | August 2011 | |
| NCT05655416 | Completed | N/A | Treatment of Great Saphenous Vein Varicosities | April 1, 2014 | April 5, 2021 |
| NCT01231373 | Completed | Phase 3 | Polidocanol Endovenous Microfoam (PEM) Versus Vehicle for the Treatment of Saphenofemoral Junction (SFJ) Incompetence | November 2010 | August 2014 |
| NCT01428076 | Completed | Phase 1 | Pharmacokinetic Study of Polidocanol Endovenous Microfoam (PEM) | August 2011 | January 2012 |
| NCT01508624 | Completed | N/A | Evaluation of Interventions to Improve Pain Relief, Perceived Anxiety and Recovery in Participants Receiving Office Based Surgery | April 2012 | November 2013 |
| NCT01611324 | Completed | Phase 4 | Painless Local Infiltration Anesthesia | May 2012 | December 2012 |
| NCT01637181 | Completed | N/A | Clinical Trial of Endovenous 940 and 1470 Laser Ablation for Treating Great Saphenous Veins | May 2012 | December 2014 |
| NCT05398458 | Completed | Management of a Giant Lymphocele Following Varicose Vein Surgery - A Case Report | January 1, 2019 | April 21, 2022 | |
| NCT00430326 | Completed | Phase 2 | Juvista (Avotermin) in Scars Following Varicose Vein Removal | November 2006 | April 2009 |
| NCT01942941 | Completed | N/A | Peripheral Vascular Disease and Nerve Stimulation | June 2013 | May 2014 |
| NCT05372146 | Completed | N/A | Great Saphenous Vein Sparing Segmental Radiofrequency Ablation in Varicose Veins Patients | November 1, 2019 | February 27, 2022 |
| NCT01993914 | Completed | Prevalence of MTHFR Polymorphisms in Venous Disease | February 2011 | November 2014 | |
| NCT02010723 | Completed | Phase 4 | Surgery Versus Sclerotherapy for Isolated Accessory Great Saphenous Vein Varicosis | June 2006 | February 2012 |
| NCT02017106 | Completed | N/A | Concomitant or Sequential Phlebectomy After Endovenous Laser Therapy for Varicose Veins | April 2006 | April 2010 |
| NCT02046967 | Completed | N/A | Steam Ablation Versus Endovenous Laser Ablation for the Treatment of Great Saphenous Veins | November 2009 | March 2013 |
| NCT02051439 | Completed | N/A | The Party Balloon Assisted Valsalva in Diagnosis of Superficial Venous Valvular Reflux of Lower Limb | January 2012 | May 2012 |
| NCT02054325 | Completed | Phase 4 | Study Protocol Comparing Polidocanol Versus Hypertonic Glucose for Treatment of Reticular Veins | September 2012 | December 2014 |
| NCT02080013 | Completed | N/A | Endovenous Radiofrequency Versus Laser Ablation for the Treatment of Great Saphenous Vein Reflux | December 2011 | November 2013 |
| NCT02114307 | Completed | N/A | REVITIVE for the Treatment of Patients With Venous Insufficiency | March 1, 2014 | October 1, 2014 |
| NCT05261412 | Completed | N/A | Varicose Vein Education and Informed coNsent (VVEIN) Study | April 4, 2022 | July 31, 2023 |
| NCT05247333 | Completed | N/A | Implementation of a Minor Ailment Service in Community Pharmacy Practice | October 1, 2020 | September 30, 2023 |
| NCT02335580 | Completed | Effect of Portal Vein Thrombosis on the Prognosis of Liver Cirrhosis | December 2014 | December 2022 | |
| NCT02345018 | Completed | Primary Insufficiency of the GSV With a Diameter >/= 12 mm, Antero-lateral Branches, or Below the Knee | June 2016 | April 2022 | |
| NCT02441881 | Completed | N/A | Trial of Radiofrequency Thermo-ablation Treatments of Great Saphenous Varicose Veins (3-RF Study) | September 5, 2014 | September 30, 2017 |
| NCT02454452 | Completed | N/A | Comparison of Radiofrequency, Vein Stripping and CHIVA for Venous Insufficency | February 2013 | August 2017 |
| NCT02462720 | Completed | Phase 4 | COMFORT: A Multicenter, Open-label, Randomized, Crossover Study | May 2015 | March 2016 |
| NCT02504684 | Completed | N/A | Treatment of Saphenous Vein Reflux With 1920-nm Diode Laser | February 2013 | January 2015 |
| NCT02522845 | Completed | N/A | Compression Therapy Following Endothermal Ablation | May 2015 | May 2019 |
| NCT05058989 | Completed | The Evaluation of the Pathophysiology of Varicose Veins in Pregnancy | June 1, 2021 | December 1, 2022 | |
| NCT02558426 | Completed | Estrogen Receptors and Chronic Venous Disease | January 2015 | September 2015 | |
| NCT02584842 | Completed | Rivaroxaban in Endovenous Laser Ablation With and Without Miniphlebectomy | January 2012 | December 2014 | |
| NCT02627846 | Completed | Phase 4 | Laser Ablation Versus Mechanochemical Ablation Trial | June 1, 2015 | September 4, 2023 |
| NCT02655406 | Completed | N/A | COmpressioN Following Endovenous TreatmenT of Incompetent Varicose Veins | January 2016 | August 2021 |
| NCT02657252 | Completed | Phase 4 | Polidocanol Versus Glucose Treatment of Telangiectasia Trial | January 2015 | November 2016 |
| NCT04933591 | Completed | N/A | Impact of Treatment With VENARUS® on the Level of Monocyte Chemoattractant Protein 1 in Varicose Veins Blood | September 1, 2020 | September 28, 2021 |
| NCT02867501 | Completed | Venous Distension in Patients With Aneurysmatic Arterial Disease | May 2016 | March 28, 2017 | |
| NCT02870127 | Completed | Clinical Investigation and Molecular Forms of Family Disease of Varicose | June 1, 2013 | December 19, 2016 | |
| NCT02890563 | Completed | N/A | Compression Therapy Following Truncal Vein Endothermal Ablation And Distal Sclerotherapy | August 2016 | March 2019 |
| NCT04280679 | Completed | N/A | Treatment of Insufficient Superficial and Perforatring Veins of the Lower Limb Using HIFU | March 3, 2020 | September 10, 2020 |
| NCT03613376 | Completed | N/A | Compression And Functional Ability After Endovenous Varicose Vein Treatment | May 21, 2018 | January 1, 2021 |
| NCT00442364 | Completed | Phase 2 | Safety Study of Varisolve® Procedure for Treatment of Varicose Veins in Patients With Right-to-left Cardiac Shunt | March 2007 | August 2009 |
| NCT06290973 | Completed | Quality of Life and Health Perception After Surgery of Varicose Veins | January 2, 2023 | November 14, 2023 | |
| NCT00621062 | Completed | N/A | Prospective Randomized Trial Comparing the New Endovenous Procedures Versus Conventional Surgery for Varicose Veins Due to Great Saphenous Vein Incompetence | January 2008 | January 2014 |
| NCT06192472 | Completed | N/A | Investigation Into the Pathophysiology and Treatment of Varicose Veins | April 2013 | September 2015 |
| NCT00758420 | Completed | Phase 2/Phase 3 | Randomized, Single Blind, Placebo Controlled, to Evaluate Efficacy and Safety of Polidocanol Injectable Foam for Treatment of Symptomatic, Visible Varicose Veins With SFJ Incompetence | October 2008 | August 2009 |
| NCT03810677 | Completed | Treatment of Varicose Veins With the ELVeS® Radial® 2ring Slim Fiber. Are There Limitations? | April 15, 2019 | March 8, 2021 | |
| NCT03653793 | Completed | N/A | LivRelief Varicose Veins Cream in the Treatment of Varicose Veins | May 23, 2017 | August 28, 2017 |
| NCT04036734 | Completed | N/A | Longitudinal or Transverse Orientation of Ultrasound Probe in Minimally Invasive Venous Surgery. | July 24, 2019 | March 1, 2020 |
| NCT03037827 | Completed | N/A | The Effect of Laser Power and Fiber Traction Speed on the Outcomes of Endovenous Laser Ablation | January 30, 2017 | May 19, 2021 |
| NCT04006184 | Completed | Retrospective Review of Saphenous Vein Incompetence: Venaseal Versus Endovenous Thermal Ablation | June 14, 2019 | August 30, 2019 | |
| NCT03283800 | Completed | N/A | Copper Impact on Venous Insufficiency and Lipodermatosclerosis | September 23, 2015 | January 9, 2017 |
| NCT03893201 | Completed | A Singapore Venaseal Real World Post-Market Evaluation Study | April 11, 2018 | January 31, 2020 | |
| NCT03856814 | Completed | Market Penetration of Laser Therapy in Venous Surgery: Ziekenhuis Oost-Limburg - Ziekenhuis Maas en Kempen Center Experience | March 15, 2019 | November 8, 2023 | |
| NCT03392753 | Completed | N/A | Mechanochemical Ablation Compared to Cyanoacrylate Adhesive | November 6, 2017 | December 31, 2021 |
| NCT03850496 | Completed | N/A | DESIVI: Dosing of Electrical Stimulation in Venous Insufficiency | November 1, 2015 | October 31, 2016 |
| NCT03477227 | Completed | N/A | New Compression Hosiery Versus Standard Class II Compression Stockings After Endothermal Ablation | December 29, 2017 | December 29, 2018 |
| NCT04054440 | Enrolling by invitation | Outpatient Office Based Endovascular Procedures | June 20, 2014 | May 17, 2024 | |
| NCT05650073 | Enrolling by invitation | N/A | A Study of Soundscapes for Patient Wellbeing | June 16, 2023 | June 2024 |
| NCT05380895 | Not yet recruiting | Comparison of Daytime Surgery in Varicose Veins Patients With and Without Superficial Venous Thrombosis | June 10, 2022 | June 10, 2025 | |
| NCT05508581 | Not yet recruiting | N/A | Microwaves Ablation of Varicose Veins | October 15, 2023 | December 15, 2023 |
| NCT05663359 | Recruiting | N/A | Study on Treatment of Varicose Veins by Endovenous Laser (1940 nm vs 1470 nm) | February 24, 2023 | February 2031 |
| NCT06271798 | Recruiting | N/A | Effect Of Resistive Exercises Versus Aerobic Exercises On Varicose Veins In Postmenopausal Women | February 20, 2024 | April 19, 2024 |
| NCT03416413 | Recruiting | Phase 4 | Study of Foam Sclerotherapy Versus Ambulatory Phlebectomy | February 1, 2018 | June 30, 2024 |
| NCT06332833 | Recruiting | Availability of Venous Conduits in Patients With Varicose Veins for Arterial Bypass Surgery | December 1, 2023 | May 31, 2024 | |
| NCT04231942 | Recruiting | N/A | Elastic Compression Stockings and Varicose Veins Recurrence | December 16, 2019 | December 31, 2025 |
| NCT05840991 | Recruiting | N/A | Effect of Short-term Compression Therapy After Thermal Ablation for Varicose Veins | May 22, 2023 | December 31, 2023 |
| NCT05735639 | Recruiting | Phase 4 | THRomboprophylaxis in Individuals Undergoing Superficial endoVEnous Treatment (THRIVE) | January 22, 2024 | December 31, 2026 |
| NCT03041805 | Recruiting | Caprini Score in Venous Surgery: a Prospective Cohort Study | January 1, 2017 | January 1, 2025 | |
| NCT03057067 | Terminated | N/A | Embolization of Pelvic Varicosities in Patients With Pelvic Congestion Syndrome | May 19, 2017 | February 7, 2019 |
| NCT05312970 | Terminated | Phase 4 | Varithena Versus Endothermal Ablation of the Great Saphenous Vein (VERITAS) | February 10, 2023 | April 4, 2024 |
| NCT00618514 | Terminated | N/A | The BRILLIANT Study | June 2008 | August 2009 |
| NCT02557542 | Terminated | N/A | Pilot RCT Evaluating a One Stop Vein Clinic | October 2015 | March 2021 |
| NCT00500669 | Terminated | Phase 3 | A Randomised Study to Assess Betadine in the Groin Wound of Patients Undergoing Primary Varicose Vein Surgery | June 2004 | December 2013 |
| NCT04671641 | Unknown status | N/A | Endovenous Radiofrequency Ablation Closure System in the Treatment of Varicose Veins | April 1, 2021 | October 2, 2022 |
| NCT02676908 | Unknown status | N/A | Optimum Duration of Compression Stockings After Endovenous Varicose Vein Surgery | September 2016 | August 2019 |
| NCT05122195 | Unknown status | Graduated Elastic compRession for vAricose Veins in PrEgnancy | June 1, 2021 | May 1, 2022 | |
| NCT02304146 | Unknown status | Long-term Ultrasound Guided Foam Sclerotherapy Versus Classical Surgical Stripping Study | November 2014 | October 2015 | |
| NCT02139085 | Unknown status | Phase 2 | Great Saphenous Vein Electrocoagulation | August 2014 | July 2016 |
| NCT05342779 | Unknown status | N/A | Radio Frequency Ablation Versus Stripping of Great Saphenous Vein in Management of Primary Varicose Veins , Comparative Study | June 2022 | June 2023 |
| NCT01949207 | Unknown status | N/A | RCT - Does Treating Incompetent Perforators Reduce Recurrence? | July 2014 | September 2019 |
| NCT01909024 | Unknown status | N/A | Pelvic Embolisation to Reduce Recurrent Varicose Veins - Recurrent | July 2013 | December 2018 |
| NCT01901731 | Unknown status | N/A | Pelvic Embolisation to Reduce Recurrent Varicose Veins - Primary | March 2014 | October 2018 |
| NCT01332838 | Unknown status | N/A | A Comparison of Specialized Versus Standard Compression After Saphenous Ablation | May 2011 | June 2013 |
| NCT03685838 | Unknown status | N/A | Compression Stockings Therapy Following Mechano-Chemical Ablation (Clarivein®) | February 13, 2019 | October 1, 2022 |
| NCT03384355 | Unknown status | Ecchymosis and Coldness in Patients With Varicose Vein | January 2018 | December 2018 | |
| NCT02944331 | Unknown status | 3-4 Year Outcomes Following Endovenous Steam Ablation for Venous Insufficiency | January 1, 2017 | September 30, 2017 | |
| NCT04146168 | Unknown status | Lake Washington Vascular VenaSeal™ Post-Market Evaluation | November 2019 | March 2020 | |
| NCT04203043 | Unknown status | Phase 2 | The Prevstain Trial | February 28, 2020 | December 28, 2021 |
| NCT04339075 | Unknown status | Registry to Investigate the Efficacy and Safety of VenaBlock VeIn SEaling System for VaRicose Veins in SingApore | October 1, 2019 | October 1, 2021 | |
| NCT04339088 | Unknown status | High Intensity Focused Ultrasound in PAtients With Varicose Veins in Singapore | March 1, 2022 | December 1, 2023 | |
| NCT04384315 | Unknown status | Efficacy and Safety of Endovenous Radio Frequency (EVRF) for Treatment of Varicose Veins in Singapore | August 1, 2019 | December 1, 2022 | |
| NCT04434274 | Unknown status | MIcronized Flavonoid Fraction After MechanO-Chemical Ablation | January 1, 2019 | December 31, 2022 | |
| NCT04436549 | Unknown status | Pathology, Venous Disease, and Clinical Correlations | December 1, 2019 | October 1, 2020 | |
| NCT04441957 | Unknown status | MechanO-Chemical Ablation Versus CompreSSion | January 1, 2018 | December 31, 2021 | |
| NCT04479956 | Unknown status | N/A | Microwave Venous Ablation in Comparison to Radiofrequency Ablation, Laser Ablation and Surgical Ligation in Management of Great Saphenous Vein Incompetence | June 18, 2020 | October 30, 2021 |
| NCT04524793 | Unknown status | N/A | Efficacy and Safety of Endovenous Microwave Ablations for Treatment of Varicose Veins in Singapore | May 9, 2020 | December 2021 |
| NCT00702897 | Unknown status | Ambulatory Surgery of Lower Extremity Varicose Vein | January 2008 | ||
| NCT03744858 | Unknown status | The Role of Pyroptosis in Chronic Venous Disease | November 12, 2018 | November 12, 2020 | |
| NCT01426035 | Withdrawn | Phase 3 | Safety And Efficacy Study Of Topic Mucopolysaccharide Polysulfate Cream In The Superficial Varicose Veins Treatment | September 2014 | February 2015 |
| NCT02936271 | Withdrawn | N/A | Efficacy of Vasculera in Prevention on Post-op Pain and Edema Following Lower Extremity Venous Treatment in the Outpatient Setting | October 2016 | April 1, 2017 |
| NCT03601572 | Withdrawn | Hypnoanalgesia in Surgical and Endovenous Treatment of Varicosis | September 2, 2018 | October 1, 2018 | |
| NCT02988063 | Withdrawn | Phase 4 | Effect of PEM Treatment of Superficial Axial and Tributary Vein Reflux on Improvement of Wound Healing in VLUs | April 10, 2017 | September 12, 2017 |
| NCT03326219 | Withdrawn | N/A | Endoveneous Histologic Study | January 2017 | December 2020 |
| NCT01203397 | Withdrawn | Phase 3 | Safety And Efficacy Study Of Topic Mucopolysaccharide Polysulfate In The Superficial Varicose Veins Treatment | September 2014 | February 2015 |
| NCT01173419 | Withdrawn | N/A | Comparison Study for Safety and Efficacy of Two Devices for the Treatment of the Great Saphenous Vein | July 2010 | February 2012 |
- Disase is a (Disease Ontology)
- DOID:866
- Cross Reference ID (Disease Ontology)
- ICD10CM:I83.90
- Cross Reference ID (Disease Ontology)
- MESH:D014648
- Cross Reference ID (Disease Ontology)
- MIM:192200
- Cross Reference ID (Disease Ontology)
- NCI:C35114
- Cross Reference ID (Disease Ontology)
- SNOMEDCT_US_2023_03_01:276504003
- Cross Reference ID (Disease Ontology)
- UMLS_CUI:C0042345
- Exact Synonym (Disease Ontology)
- varices
- Exact Synonym (Disease Ontology)
- Varix
- Exact Synonym (Disease Ontology)
- Venous ectasia
- Exact Synonym (Disease Ontology)
- Venous varices
- HPO Human Phenotype ID (Human Phenotype Ontology)
- HP:0002619
- MeSH unique ID (MeSH (Medical Subject Headings))
- D014648