anal carcinoma (Cancer)

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Information
Disease name
anal carcinoma
Disease ID
DOID:4908
Description
"A anus cancer that has_material_basis_in abnormally proliferating cells derives_from epithelial cells and is located_in the anus." [url:http\://en.wikipedia.org/wiki/Anal_cancer]
Disease area statistics
Chromosome band
Gene symbol Chromosome Start Stop The number of variant
MET 7 116,672,196 116,798,377 4
HRAS 11 532,243 535,550 2
RET 10 43,077,069 43,130,351 2
KDR 4 55,078,481 55,125,595 2
TP53 17 7,668,421 7,687,490 2
EGFR 7 55,019,017 55,211,628 2
APC 5 112,737,885 112,846,239 2
KIT 4 54,657,913 54,740,770 2
Annotation
Genes Mutation Description Source Links
NCT ID Status Phase Summary Start date Completion date
NCT02816879 Active, not recruiting N/A Anal Cytology Collection Procedures in Predicting High-Grade Anal Dysplasia in Men Who Have Sex With Men August 1, 2013 June 1, 2025
NCT00867464 Active, not recruiting Extended Follow Up of Young Women in Costa Rica Who Received Vaccine for Human Papillomavirus Types 16 and 18 and Unvaccinated Controls March 30, 2009 December 31, 2023
NCT04713618 Active, not recruiting Changes in Pelvic Health, Sexual Function, and Quality of Life in Women With Pelvic Cancer Undergoing Radiation Therapy January 30, 2021 December 31, 2026
NCT04505553 Active, not recruiting Phase 2 Oral Cryotherapy Plus Acupressure and Acupuncture Versus Oral Cryotherapy for Decreasing Chemotherapy-Induced Peripheral Neuropathy From Oxaliplatin-Based Chemotherapy in Patients With Gastrointestinal Cancer June 1, 2021 September 30, 2024
NCT04272034 Active, not recruiting Phase 1 Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of INCB099318 in Participants With Advanced Solid Tumors March 26, 2021 June 20, 2026
NCT04230759 Active, not recruiting Phase 2 Radiochemotherapy +/- Durvalumab for Locally-advanced Anal Carcinoma. A Multicenter, Randomized, Phase II Trial of the German Anal Cancer Study Group January 7, 2020 March 31, 2027
NCT00423254 Completed Phase 1 Safety and Immune Response to a Multi-component Immune Based Therapy (MKC1106-PP) for Patients With Advanced Cancer. February 2007 November 2009
NCT03469596 Completed Evaluation by MRI of Anal Canal Cell Carcinoma: is There Predictive Factor? April 1, 2017 December 31, 2017
NCT05438836 Recruiting Re-optimization Based Online Adaptive Radiotherapy of Anal Cancer January 1, 2022 January 1, 2031
NCT05663502 Recruiting Collecting Blood and Tissue Sample Donations for Research for HIV/AIDS-Related Cancers May 10, 2023 August 31, 2035
NCT05787535 Recruiting Phase 1 HRYZ-T101 TCR-T Cell for HPV-18 Positive Advanced Solid Tumor March 21, 2023 September 2025
NCT02628067 Recruiting Phase 2 Study of Pembrolizumab (MK-3475) in Participants With Advanced Solid Tumors (MK-3475-158/KEYNOTE-158) December 18, 2015 May 4, 2027
NCT02408861 Recruiting Phase 1 Nivolumab and Ipilimumab in Treating Patients With HIV Associated Relapsed or Refractory Classical Hodgkin Lymphoma or Solid Tumors That Are Metastatic or Cannot Be Removed by Surgery October 21, 2015 July 1, 2024
NCT04802876 Recruiting Phase 2 Efficacy of Tislelizumab and Spartalizumab Across Multiple Cancer-types in Patients With PD1-high mRNA Expressing Tumors April 12, 2021 March 31, 2027
NCT03241680 Unknown status N/A Study of Anal Cytologies in Patients With High Grade Cervical Intraepithelial Neoplasia (CIN II and III) August 2, 2017 May 31, 2018
NCT02369939 Unknown status Phase 3 Effects of Deep Regional Hyperthermia in Patients With Anal Carcinoma Treated by Standard Radiochemotherapy December 2014 April 2021
NCT01877135 Unknown status Malignant Progression of Anal Intra-epithelial Neoplasia in a Cohort of Patients August 2013 June 2019
Disase is a (Disease Ontology)
DOID:14110
Cross Reference ID (Disease Ontology)
MESH:D001005
Cross Reference ID (Disease Ontology)
NCI:C9291
Cross Reference ID (Disease Ontology)
SNOMEDCT_US_2023_03_01:187762000
Cross Reference ID (Disease Ontology)
UMLS_CUI:C0279637
Exact Synonym (Disease Ontology)
Ca anus
Exact Synonym (Disease Ontology)
carcinoma of anus