bile duct cancer (Cancer)

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Information
Disease name
bile duct cancer
Disease ID
DOID:4606
Description
"A biliary tract cancer that is located_in the bile duct." [url:http\://www.cancer.gov/dictionary/?CdrID=527370]
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
Genes Mutation Description Source Links
NCT ID Status Phase Summary Start date Completion date
NCT04660929 Active, not recruiting Phase 1 CAR-macrophages for the Treatment of HER2 Overexpressing Solid Tumors February 2, 2021 December 31, 2024
NCT04763642 Active, not recruiting N/A The Comparison of Miniinvasive and Open Pancreaticoduodenectomy for Cancer Pancreaticobiliary Zone January 1, 2020 January 1, 2025
NCT04853017 Active, not recruiting Phase 1 A Study of ELI-002 in Subjects With KRAS Mutated Pancreatic Ductal Adenocarcinoma (PDAC) and Other Solid Tumors October 4, 2021 March 2026
NCT04383210 Active, not recruiting Phase 2 Study of Seribantumab in Adult Patients With NRG1 Gene Fusion Positive Advanced Solid Tumors September 29, 2020 March 2025
NCT05662488 Active, not recruiting FAPI PET for Response Evaluation and Prognosis Prediction in Liver and Biliary Cancer Patients Treated With PD-1 Combination Therapy September 1, 2020 August 30, 2023
NCT04298021 Active, not recruiting Phase 2 DDR-Umbrella Study of DDR Targeting Agents in Advanced Biliary Tract Cancer June 25, 2020 December 31, 2024
NCT04164069 Active, not recruiting Phase 1 Dasatinib for the Prevention of Oxaliplatin-Induced Neuropathy in Patients With Metastatic Gastrointestinal Cancer Receiving FOLFOX Chemotherapy With or Without Bevacizumab September 2, 2020 December 31, 2023
NCT04152018 Active, not recruiting Phase 1 Study of PF-06940434 in Patients With Advanced or Metastatic Solid Tumors. November 13, 2019 August 30, 2024
NCT03525067 Completed Colonization of Bile Ducts and Postoperative Infectious Complications of Pancreaticoduodenectomies February 1, 2017 April 2, 2018
NCT00628186 Completed N/A Randomized Controlled Trial on Pancreatic Stent Tube in Pancreaticoduodenectomy April 2005 February 2008
NCT00639314 Completed N/A Trial on the Evaluation of Pylorus-ring in Pancreaticoduodenectomy October 2005 March 2011
NCT00779688 Completed A Registry of Patients Undergoing Cellvizio Endomicroscopy and Endoscopic Retrograde Cholangiopancreatography(ERCP) Imaging Procedures for Diagnosing Pancreatic and Bile Duct Cancers November 2008 October 2010
NCT01134276 Completed N/A Comparison Between Internal and External Preoperative Biliary Drainage in Periampullary Cancers August 2010 May 2013
NCT01256034 Completed Phase 4 Effects of Preoperative Immunonutrition in Patients Undergoing Pancreaticoduodenectomy May 2009 March 2012
NCT01256047 Completed Phase 4 Effects of Preoperative Immunonutrition in Patients Undergoing Hepatectomy May 2009 March 2014
NCT04596865 Completed Recurrence After Whipple's (RAW) Study October 12, 2020 June 30, 2023
NCT03058289 Completed Phase 1/Phase 2 A Phase 1/2 Safety Study of Intratumorally Dosed INT230-6 February 9, 2017 February 22, 2023
NCT04476082 Completed Nutrition in Gastrointestinal Tumors June 25, 2020 December 6, 2022
NCT03111732 Completed Phase 2 Pembrolizumab, a Monoclonal Antibody Against PD-1, in Combination With Capecitabine and Oxaliplatin (CAPOX) in People With Advanced Biliary Tract Carcinoma (BTC) June 14, 2017 November 8, 2021
NCT03602079 Completed Phase 1/Phase 2 Study of A166 in Patients With Relapsed/Refractory Cancers Expressing HER2 Antigen or Having Amplified HER2 Gene July 16, 2018 January 12, 2022
NCT05266300 Completed Implementation and Quality Assurance of DPYD-genotyping in Patients Treated With Fluoropyrimidines. September 1, 2020 October 1, 2022
NCT04937322 Completed Radio Frequency Ablation in the Management of Pancreatico-biliary Disorders: A Multicenter Registry. January 25, 2016 March 30, 2021
NCT01640522 Completed N/A Comprehensive Electronic Cancer Support System for the Treatment of Cancer Related Symptoms January 2008 December 2014
NCT00280709 Completed Phase 4 Biliary Metal Stent Study: Metal Stents for Management of Distal Malignant Biliary Obstruction January 2006 August 2010
NCT01954745 Completed Phase 2 Cabozantinib (XL-184) Monotherapy for Advanced Cholangiocarcinoma September 2013 June 2016
NCT00183846 Completed Phase 1 Study of Irinotecan Administered as a Continuous Infusion and Radiation Therapy for Upper Gastrointestinal Cancers December 2000 July 2009
NCT02028845 Completed N/A Loop-tipped Guidewire in Selective Biliary Cannulation January 2014 December 2015
NCT02375880 Completed Phase 1 Study of DKN-01 and Gemcitabine/Cisplatin in Patients With Carcinoma to Primary to the Intra- or Extra-Hepatic Biliary System or Gallbladder June 2015 July 2018
NCT02591030 Completed Phase 2/Phase 3 Safety and Efficacy of Modified Folfirinox Versus Gemcis in Bile Duct Tumours December 15, 2015 January 16, 2020
NCT00579865 Completed Quality Of Life in Patients With Malignant Biliary Obstruction May 2005 January 2010
NCT02821754 Completed Phase 2 A Pilot Study of Combined Immune Checkpoint Inhibition in Combination With Ablative Therapies in Subjects With Hepatocellular Carcinoma (HCC) or Biliary Tract Carcinomas (BTC) July 5, 2016 December 31, 2022
NCT02841800 Completed N/A Intra-luminal Radiofrequency Ablation for Inoperable Malignant Biliary Stenosis June 2016 May 10, 2019
NCT02853474 Completed Phase 3 Early Palliative Care in Patients With Metastatic Upper Gastrointestinal Cancers Treated With First-line Chemotherapy October 2016 December 2022
NCT06076252 Enrolling by invitation N/A Modified vs Conventional Blumgart Anastomosis of LPD for the Effects of Pancreatic Fistula of Periampullary Carcinoma July 1, 2023 August 31, 2028
NCT05706974 Not yet recruiting Looking At Bile Duct Cancer Patient Experience Patterns in Medical Trials February 2024 February 2026
NCT06274879 Not yet recruiting Phase 2 Safety of Biliary Intraductal Radiofrequency Ablation in Patients With Unresectable Extrahepatic Biliary Tract Cancer May 1, 2024 April 30, 2026
NCT05911425 Not yet recruiting Phase 2 Combined Treatment of Treated Bile Duct Cancer July 1, 2023 June 30, 2025
NCT06175845 Not yet recruiting N/A Endoscopic Radiofrequency Ablation for Unresectable Cholangiocarcinoma February 2024 July 2026
NCT06453590 Recruiting N/A Treatment of Distal Malignant Biliary Obstruction by Uncovered, Partially Covered, or Fully Covered Metal Stents February 4, 2020 January 15, 2026
NCT01915225 Recruiting Obtaining Solid Tumor Tissue From People Having Biopsy or Surgery for Certain Types of Cancer July 21, 2013
NCT02012699 Recruiting Integrated Cancer Repository for Cancer Research November 1, 2013 December 2099
NCT02628067 Recruiting Phase 2 Study of Pembrolizumab (MK-3475) in Participants With Advanced Solid Tumors (MK-3475-158/KEYNOTE-158) December 18, 2015 May 4, 2027
NCT04028479 Recruiting The Registry of Oncology Outcomes Associated With Testing and Treatment May 5, 2021 October 1, 2031
NCT04104230 Recruiting Quebec Pancreas Cancer Study March 12, 2012 January 2025
NCT04298008 Recruiting Phase 2 AZD6738 Plus Durvalumab in Biliary Tract Cancer June 25, 2020 December 31, 2025
NCT04907643 Recruiting N/A Virtual Reality for GI Cancer Pain to Improve Patient Reported Outcomes October 5, 2021 March 2026
NCT04993131 Recruiting N/A Liver Transplantation for Non-resectable Perihilar Cholangiocarcinoma September 1, 2021 May 31, 2045
NCT05000294 Recruiting Phase 1/Phase 2 Atezolizumab Plus Tivozanib in Immunologically Cold Tumor Types December 7, 2021 December 2025
NCT05155878 Recruiting Prognostic Factors in Periampullary Tumors and Cysts September 1, 2021 January 1, 2040
NCT05277766 Recruiting Phase 1 Intraperitoneal Aerosolized Nanoliposomal Irinotecan (Nal-IRI) in Peritoneal Carcinomatosis From Gastrointestinal Cancer November 21, 2022 January 1, 2027
NCT05286814 Recruiting Phase 2 M9241 in Combination With Hepatic Artery Infusion Pump (HAIP) and Systemic Therapy for Subjects With Metastatic Colorectal Cancer or Intrahepatic Cholangiocarcinoma October 24, 2022 December 31, 2028
NCT05346484 Recruiting Phase 1 A Study of CF33-hNIS (VAXINIA), an Oncolytic Virus, as Monotherapy or in Combination With Pembrolizumab in Adults With Metastatic or Advanced Solid Tumors May 17, 2022 January 2025
NCT05519319 Recruiting N/A Safety and Efficacy of PDT vs RFA vs PDT+RFA for the Treatment of Extrahepatic Cholangiocarcinoma January 1, 2023 June 1, 2026
NCT05655949 Recruiting Phase 2 Y-90 With Durvalumab/Gem/Cis in Intrahepatic Cholangio February 13, 2024 December 1, 2027
NCT05712356 Recruiting Phase 2 A Study of LSTA1 When Added to Standard of Care Versus Standard of Care Alone in Patients With Advanced Solid Tumors August 24, 2023 December 2025
NCT05849480 Recruiting Phase 1/Phase 2 A Study of CDX-1140, a CD40 Agonist, in Combination With Capecitabine and Oxaliplatin (CAPOX) and Keytruda in Subjects With Biliary Tract Carcinoma (BTC) May 8, 2024 June 1, 2042
NCT05858736 Recruiting Phase 1 Safety, PK and Efficacy of AI-061 in Advanced Solid Tumors July 11, 2023 June 15, 2025
NCT06028724 Recruiting A Study on the Prevalence of Clinically Useful Mutations in Solid Tumor Characterized by Next Generation Sequencing Methods on Liquid Biopsy Analysis (POPCORN) May 26, 2023 May 31, 2030
NCT06043466 Recruiting Phase 1 A Clinical Trial Targeting CEA Chimeric Antigen Receptor T (CAR-T) for CEA Positive Advanced Malignant Solid Tumors August 11, 2023 December 31, 2027
NCT06048133 Recruiting Phase 2 Study of Gemcitabine, Cisplatin, AB680 and AB122 During First Line Treatment of Advanced Biliary Tract Cancers (QUIC) March 8, 2024 July 2025
NCT06256055 Recruiting Phase 1 Phase 1 Study of UCMYM802 Injection in Mesothelin-positive Advanced Malignant Solid Tumors March 5, 2024 April 2025
NCT06277531 Recruiting Evaluation of diagnostiC Capacity of eccDNAs as Biomarkers in Indetermined biLiary Stricture(ECCBILE) March 1, 2024 March 1, 2027
NCT06340620 Recruiting N/A EUS Examination Using EndoSound Vision System vs. Standard Echoendoscope March 25, 2024 December 2027
NCT00624182 Suspended Phase 1 Gemcitabine With Peptide Vaccine Therapy in Treating Patients With Bile Duct Cancer February 2008 December 2016
NCT04076761 Terminated Phase 2 Study of TRIFLURIDINE/TIPIRACIL in Previously Treated Cholangiocarcinoma December 11, 2019 September 30, 2022
NCT01151761 Terminated Phase 2 Phase II SBRT & Chemo for Unresectable Cholangiocarcinoma Followed by Liver Transplantation January 2011 July 2012
NCT00832637 Terminated Phase 2 Gemcitabine, Oxaliplatin, Tarceva &/or Cisplatin in HCC & Biliary Tree Cancers August 2007 March 15, 2017
NCT04566133 Terminated Phase 2 Combination of Trametinib (MEK Inhibitor) and Hydroxychloroquine (HCQ) (Autophagy Inhibitor) in Patients With KRAS Mutation Refractory Bile Tract Carcinoma (BTC). February 15, 2022 December 31, 2022
NCT05418543 Unknown status N/A CH-EUS in Diagnosis of Inoperable Bile Duct Tumors January 1, 2022 December 30, 2022
NCT03763214 Unknown status N/A PTFE Stents for Treatment of Malignant Biliary Strictures March 1, 2018 September 2020
NCT03475966 Unknown status N/A Improving Outcomes in Cancer Patients With a Nutritional and Physical Conditioning Prehabilitation Program February 22, 2017 June 30, 2022
NCT03086993 Unknown status Phase 2/Phase 3 Percutaneous Hepatic Perfusion vs. Cisplatin/Gemcitabine in Patients With Intrahepatic Cholangiocarcinoma April 10, 2018 May 2023
NCT02954302 Unknown status N/A Proximal Roux-en-y Gastrojejunal Anastomosis on Delayed Gastric Emptying After Pylorus-resecting Pancreaticoduodenectomy September 2016 December 2018
NCT01438385 Unknown status Interventional Endoscopy Database for Pancreatico-biliary, Gastrointestinal and Esophageal Disorders July 2011 December 30, 2017
NCT00356161 Unknown status Phase 2 HAI Via Interventionally Implanted Port Catheter Systems April 2002 April 2008
NCT04014478 Unknown status N/A A Clinical Trial to Evaluate Safety and Efficacy of Endovascualr Denervation in Treatment of Cancer Pain July 15, 2019 July 15, 2021
NCT03951324 Unknown status Volumetric Laser Endomicroscopy's (VLE) Diagnostic Accuracy Validation Study: Impact on Clinical Management Study May 10, 2019 December 31, 2019
NCT03788655 Unknown status Metal Stents (Moving Cell Stent) for Inoperable Tumors of the Bile Duct Tract December 31, 2018 June 2021
NCT00809081 Unknown status Phase 3 Early Enteral Feeding After Pylorus Preserving Pancreatoduodenectomy July 2007 January 2010
NCT01317069 Unknown status Phase 2 A Randomized, Open, Prospective Clinical Research of Fluorouracil Implant to Improve Surgical Gallbladder Cancer and Bile Duct Cancer June 2010 April 2013
NCT01755013 Unknown status Phase 2/Phase 3 Photodynamic Therapy (PDT) for Palliation of Cholangiocarcinoma February 2012 March 22, 2018
NCT01522573 Unknown status T-EUS for Gastrointestinal Disorders: A Multicenter Registry November 2011 December 30, 2018
NCT01111591 Unknown status Phase 4 Cyclooxygenase-2 Inhibitor for Adjuvant Anticancer Effect in Patients With Biliary-pancreas Cancer November 2008 June 2017
NCT01439698 Unknown status Radio Frequency Ablation in the Management of Pancreatico-biliary Disorders: A Multicenter Registry September 2011 December 30, 2018
NCT02446379 Withdrawn Use of the EnLightTM and LightPathTM Imaging Systems in Gastrointestinal Tumour Surgery
NCT04404647 Withdrawn N/A Irreversible Electroporation of Unresectable Liver Tumors June 1, 2020 March 30, 2025
Disase is a (Disease Ontology)
DOID:4607
Cross Reference ID (Disease Ontology)
ICD10CM:C24.0
Cross Reference ID (Disease Ontology)
ICD9CM:156.1
Cross Reference ID (Disease Ontology)
MESH:D001650
Cross Reference ID (Disease Ontology)
NCI:C2898
Cross Reference ID (Disease Ontology)
NCI:C7483
Cross Reference ID (Disease Ontology)
SNOMEDCT_US_2023_03_01:93790004
Cross Reference ID (Disease Ontology)
UMLS_CUI:C0005396
Cross Reference ID (Disease Ontology)
UMLS_CUI:C0153453
Exact Synonym (Disease Ontology)
bile duct tumor
Exact Synonym (Disease Ontology)
Ca extrahepatic bile ducts
Exact Synonym (Disease Ontology)
malignant neoplasm of the extrahepatic bile duct