papillary renal cell carcinoma (Cancer)

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Information
Disease name
papillary renal cell carcinoma
Disease ID
DOID:4465
Description
"A renal cell carcinoma that is characterized by the development of multiple, bilateral papillary renal tumors." [url:http\://cancergenome.nih.gov/cancersselected/kidneypapillary, url:http\://www.omim.org/entry/605074]
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
Genes Mutation Description Source Links
NCT ID Status Phase Summary Start date Completion date
NCT03541902 Active, not recruiting Phase 2 Cabozantinib or Sunitinib Malate in Treating Participants With Metastatic Variant Histology Renal Cell Carcinoma May 15, 2018 July 31, 2025
NCT01767636 Active, not recruiting Phase 2 Pazopanib Hydrochloride in Treating Patients With Metastatic Kidney Cancer May 16, 2013 November 16, 2024
NCT03635892 Active, not recruiting Phase 2 A Study of Nivolumab In Combination With Cabozantinib in Patients With Non-Clear Cell Renal Cell Carcinoma August 13, 2018 August 2024
NCT00126503 Completed Phase 1/Phase 2 Sorafenib Tosylate and Bevacizumab in Treating Patients With Advanced Kidney Cancer May 2005 February 2012
NCT00335556 Completed Phase 2 Combination Chemotherapy, Radiation Therapy, and/or Surgery in Treating Patients With High-Risk Kidney Tumors June 2006
NCT02489695 Completed Phase 2 Axitinib in1st Line Treatment for Patients With Advanced or Metastatic Papillary Renal Cell Carcinoma October 2015 July 2019
NCT06146777 Not yet recruiting Phase 3 Multi-classifier System for Stratifying Stage III Papillary Renal Cell Carcinoma of Receiving Adjuvant Therapy December 1, 2023 December 1, 2030
NCT06339138 Recruiting Identification of Novel High Quality Methylated DNA Markers in Renal Tumors: Whole Methylome Discovery, Tissue Validation, and Feasibility Testing In Blood and Urine, The INQUIRE Study February 20, 2018 January 31, 2027
NCT00898365 Recruiting Study of Kidney Tumors in Younger Patients February 27, 2006
NCT03866382 Recruiting Phase 2 Testing the Effectiveness of Two Immunotherapy Drugs (Nivolumab and Ipilimumab) With One Anti-cancer Targeted Drug (Cabozantinib) for Rare Genitourinary Tumors May 13, 2019 February 28, 2025
NCT04071223 Recruiting Phase 2 Testing the Addition of a New Anti-cancer Drug, Radium-223 Dichloride, to the Usual Treatment (Cabozantinib) for Advanced Renal Cell Cancer That Has Spread to the Bone, RadiCaL Study July 29, 2020 October 1, 2024
NCT04413123 Recruiting Phase 2 Cabozantinib In Combo With NIVO + IPI In Advanced NCCRCC November 5, 2020 December 20, 2025
NCT04981509 Recruiting Phase 2 Testing of Bevacizumab, Erlotinib, and Atezolizumab in Combination for Advanced-Stage Kidney Cancer June 10, 2022 December 31, 2024
NCT05043090 Recruiting Phase 3 Savolitinib Plus Durvalumab Versus Sunitinib and Durvalumab Monotherapy in MET-Driven, Unresectable and Locally Advanced or Metastatic PRCC October 28, 2021 September 14, 2026
NCT05620134 Recruiting Phase 1/Phase 2 Study of JK08 in Patients With Unresectable Locally Advanced or Metastatic Cancer October 17, 2022 February 20, 2026
NCT04623502 Recruiting N/A An Investigation of Kidney and Urothelial Tumor Metabolism in Patients Undergoing Surgical Resection and/or Biopsy September 30, 2019 September 30, 2026
NCT02837991 Terminated Phase 1 A Dose Escalation, Safety and Activity Study of CDX-014 in Patients With Renal Cell Carcinoma and Ovarian Clear Cell Carcinoma June 2016 November 16, 2018
NCT00098618 Terminated Phase 2 Sorafenib and Interferon Alfa in Treating Patients With Locally Advanced or Metastatic Kidney Cancer October 2004
NCT04603365 Withdrawn Phase 2 Pamiparib and Temozolomide for the Treatment of Hereditary Leiomyomatosis and Renal Cell Cancer October 18, 2021 May 7, 2023
Disase is a (Disease Ontology)
DOID:4450
Cross Reference ID (Disease Ontology)
GARD:9572
Cross Reference ID (Disease Ontology)
MESH:C538614
Cross Reference ID (Disease Ontology)
MESH:D002292
Cross Reference ID (Disease Ontology)
MIM:605074
Cross Reference ID (Disease Ontology)
NCI:C27890
Cross Reference ID (Disease Ontology)
NCI:C6975
Cross Reference ID (Disease Ontology)
SNOMEDCT_US_2023_03_01:4797003
Cross Reference ID (Disease Ontology)
UMLS_CUI:C1306837
Cross Reference ID (Disease Ontology)
UMLS_CUI:C1336078
Exact Synonym (Disease Ontology)
Chromophil carcinoma of kidney
Exact Synonym (Disease Ontology)
papillary kidney carcinoma
Exact Synonym (Disease Ontology)
sporadic papillary renal cell carcinoma
HPO alt_id (Human Phenotype Ontology)
HP:0006776
HPO Human Phenotype ID (Human Phenotype Ontology)
HP:0006766
OrphaNumber from OrphaNet (Orphanet)
319298