bladder urothelial carcinoma (Cancer)

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Information
Disease name
bladder urothelial carcinoma
Disease ID
DOID:4006
Description
"A bladder carcinoma that has_material_basis_in transitional cells located_in the lining of the bladder." [url:http\://cancergenome.nih.gov/cancersselected/UrothelialBladderCarcinoma, url:http\://www.cancer.gov/dictionary?cdrid=46629]
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
Genes Mutation Description Source Links
NCT ID Status Phase Summary Start date Completion date
NCT04167631 Active, not recruiting N/A Can VI-RADS/ADC Accurately Stage Bladder Cancer?? January 1, 2019 January 1, 2024
NCT02496208 Active, not recruiting Phase 1 Cabozantinib S-malate and Nivolumab With or Without Ipilimumab in Treating Patients With Metastatic Genitourinary Tumors July 22, 2015 September 30, 2024
NCT03039413 Active, not recruiting Early Phase 1 Copper Cu-64 TP3805 PET/CT in Imaging Patients With Urothelial Cancer Undergoing Surgery or Biopsy September 28, 2016 April 2024
NCT04216290 Active, not recruiting Phase 2 A Study of Chemotherapy and Radiation Therapy Compared to Chemotherapy and Radiation Therapy Plus MEDI4736 (Durvalumab) Immunotherapy for Bladder Cancer Which Has Spread to the Lymph Nodes (The INSPIRE Study) March 17, 2021 June 30, 2026
NCT03473730 Active, not recruiting Early Phase 1 Daratumumab in Treating Patients With Muscle Invasive Bladder Cancer or Metastatic Kidney Cancer May 29, 2018 June 30, 2024
NCT03601455 Active, not recruiting Phase 2 Radiation Therapy and Durvalumab With or Without Tremelimumab in Treating Participants With Unresectable, Locally Advanced, or Metastatic Bladder Cancer October 26, 2018 January 31, 2026
NCT03775265 Active, not recruiting Phase 3 Chemoradiotherapy With or Without Atezolizumab in Treating Patients With Localized Muscle Invasive Bladder Cancer June 3, 2019 June 1, 2027
NCT00238420 Completed Phase 1/Phase 2 Paclitaxel and Radiation Therapy With or Without Trastuzumab in Treating Patients Who Have Undergone Surgery for Bladder Cancer July 26, 2005 May 20, 2022
NCT03329950 Completed Phase 1 A Study of CDX-1140 (CD40) as Monotherapy or in Combination in Patients With Advanced Malignancies December 1, 2017 September 13, 2022
NCT02989064 Completed Phase 1 MAGE-A10ᶜ⁷⁹⁶T for Urothelial Cancer, Melanoma or Head and Neck Cancers October 2016 June 4, 2020
NCT04200963 Completed Phase 1 A Phase 1a/b Study of IK-175 as a Single Agent and in Combination With Nivolumab in Patients With Locally Advanced or Metastatic Solid Tumors and Urothelial Carcinoma December 18, 2019 July 18, 2023
NCT04440943 Completed Phase 1 A Study of the PD-L1xCD27 Bispecific Antibody CDX-527 in Patients With Advanced Malignancies August 4, 2020 April 6, 2023
NCT06263153 Not yet recruiting Phase 2 Futibatinib in Combination With Durvalumab Prior to Cystectomy for the Treatment of Muscle-Invasive Bladder Cancer Patients Who Are Ineligible for Cisplatin-based Therapy June 1, 2024 December 31, 2025
NCT06416319 Recruiting N/A Preoperative Physical Activity Improvement With the Use of Activity Trackers Before Radical Cystectomy (PreAct) March 14, 2023 March 14, 2026
NCT04570410 Recruiting Phase 2 Primary Excision Combined With Preoperative Neoadjuvant and Adjuvant Therapy for Oligometastasis of Urothelial Carcinoma October 1, 2020 December 1, 2024
NCT04574960 Recruiting Phase 3 Neoadjuvant Upper Tract Invasive Cancer Trial (NAUTICAL) February 8, 2021 December 2025
NCT04985604 Recruiting Phase 1/Phase 2 Tovorafenib (DAY101) Monotherapy or in Combination With Other Therapies for Patients With Melanoma and Other Solid Tumors July 15, 2021 December 31, 2025
NCT05220124 Recruiting Phase 4 A Study of Probiotics Administration in the Immunotherapy of Urothelial Bladder Carcinoma January 5, 2022 November 30, 2024
NCT05296564 Recruiting Phase 1/Phase 2 Anti-NY-ESO-1 TCR-Gene Engineered Lymphocytes Given by Infusion to Patients With NY-ESO-1 -Expressing Metastatic Cancers April 1, 2022 December 30, 2027
NCT05669430 Recruiting Phase 1 A Study of GV20-0251 in Patients With Solid Tumor Malignancies March 23, 2023 June 15, 2026
NCT05788484 Recruiting Phase 1 A Study of CDX-585 in Patients With Advanced Malignancies May 11, 2023 February 2026
NCT05833997 Recruiting N/A Safety Analysis and Oncological Outcomes in HoLERT vs TURBT December 10, 2020 December 2025
NCT06167356 Recruiting Study on the Occurrence of Possible Relapses and on the Quality of Life in Patients Who Underwent TURBK. November 27, 2013 November 27, 2063
NCT06170177 Recruiting Study on the Quality of Life and Pathological State in Patients Who Underwent Radical Cystectomy February 4, 2013 February 2063
NCT03266900 Terminated Early Phase 1 A Superiority Trial to Compare Re-resection of High-grade T1 Bladder Urothelial Carcinoma to no Re-resection for Improving Progression Free Survival November 16, 2017 October 4, 2021
NCT00072137 Terminated Phase 1 Neoadjuvant Intravesical Vaccine Therapy in Treating Patients With Bladder Carcinoma Who Are Undergoing Cystectomy October 2003 November 2010
NCT03912818 Terminated Phase 2 Durvalumab and Standard Chemotherapy Before Surgery in Treating Patients With Variant Histology Bladder Cancer April 10, 2019 August 11, 2022
NCT05052372 Terminated Biomarker Research Study for Patients With FGFR-Mutant Bladder Cancer Receiving Erdafitinib November 21, 2021 December 20, 2022
NCT05012397 Terminated Phase 2 Milademetan in Advanced/Metastatic Solid Tumors November 1, 2021 October 15, 2023
NCT05027412 Unknown status N/A En Bloc TURBT With Collins Loop vs Conventional TURBT April 1, 2021 June 2023
NCT04129606 Unknown status N/A Bladder Perforation Post-TURBT: Definition, Incidence and Natural HistoryStudy July 1, 2019 July 1, 2021
NCT03138824 Unknown status N/A Storz Professional Image Enhancement System Versus White Light Imaging Assisted TURBT for Treatment of NMIBC May 15, 2017 May 1, 2018
NCT03113266 Unknown status Phase 2 Safety and Efficacy of Toripalimab for Patients With Locally Advanced or Metastatic Bladder Urothelial Carcinoma April 6, 2017 February 2022
NCT01968928 Unknown status The Role of Pyruvate Kinase M2 in Growth, Invasion and Drug Resistance in Human Urothelial Carcinoma January 2014 December 2016
NCT05564416 Withdrawn Phase 2 Testing Anti-Cancer Drugs Erdafitinib With or Without Atezolizumab in Patients With Localized Bladder Cancer Not Able to Receive Cisplatin Chemotherapy, NERA Trial October 12, 2023 November 3, 2023
Disase is a (Disease Ontology)
DOID:4007
Cross Reference ID (Disease Ontology)
NCI:C39851
Cross Reference ID (Disease Ontology)
SNOMEDCT_US_2023_03_01:393562002
Cross Reference ID (Disease Ontology)
UMLS_CUI:C0279680
Exact Synonym (Disease Ontology)
bladder transitional cell carcinoma
Exact Synonym (Disease Ontology)
transitional cell carcinoma of bladder
Exact Synonym (Disease Ontology)
urinary bladder urothelial carcinoma
Exact Synonym (Disease Ontology)
urothelial bladder carcinoma