histiocytosis

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Information
Disease name
histiocytosis
Disease ID
DOID:3405
Description
"A lymphatic system disease that is characterized by an excessive number of histiocytes." [url:http\://en.wikipedia.org/wiki/Histiocytosis, url:http\://www.nlm.nih.gov/medlineplus/ency/article/000068.htm]
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
Genes Mutation Description Source Links
NCT ID Status Phase Summary Start date Completion date
NCT03127709 Active, not recruiting A Study of Memory, Thinking, and Brain Imaging in Adults With Histiocytosis April 7, 2017 April 2025
NCT00145626 Completed Phase 2 HLA-Nonidentical Stem Cell and Natural Killer Cell Transplantation for Children Less the Two Years of Age With Hematologic Malignancies May 2004 July 2016
NCT01225718 Completed Ceftriaxone in Non-neutropenic Fever August 2010 June 25, 2016
NCT01049854 Completed Phase 2 CD34+Selection for Partially Matched Family or Matched Unrelated Adult Donor Transplant September 2011 August 2018
NCT05803629 Not yet recruiting N/A Characterizing Histiocytosis With 68Ga-FAPI PET/CT May 1, 2023 December 31, 2025
NCT04943224 Recruiting Phase 2 Optimization of the Time and Dosage of Trametinib in BRAF Negative Juvenile Patients April 1, 2021 June 23, 2026
NCT05786924 Recruiting Phase 1 A Study of BDTX-4933 in Patients With KRAS, BRAF and Select RAS/MAPK Mutation-Positive Cancers April 18, 2023 December 2026
NCT05915208 Recruiting Histiocytic Disorder Follow-up Study September 1, 2022 December 2028
NCT04437381 Recruiting Molecular Targets for the Treatment of Histiocytosis November 22, 2021 May 2025
NCT04665674 Recruiting Adult Pulmonary Langerhans Cell Histiocytosis: a National Registry-based Prospective Cohort Study January 1, 2004 December 31, 2035
NCT04943198 Recruiting Phase 2 Optimization of the Time and Dosage of Vemurafenib in BRAF Positive Juvenile Patients With Refractory Histiocytosis April 1, 2021 June 23, 2026
NCT04943211 Recruiting Phase 3 Determination of Molecular Status, the Efficacy and Safety of Fluorodeoxyglucose in PET-CT Imaging April 1, 2021 June 23, 2026
NCT02012231 Terminated Phase 1 Phase I/IIa Study to Evaluate the Safety, PK, PD, and Preliminary Efficacy of PLX8394 in Patients With Advanced Cancers. February 2014 June 2015
NCT01050439 Terminated Phase 2 Unrelated Donor Transplant for Malignant and Non-Malignant Disorders November 2002 April 2011
Disase is a (Disease Ontology)
DOID:75
Cross Reference ID (Disease Ontology)
MESH:D015614
Cross Reference ID (Disease Ontology)
NCI:C3106
Cross Reference ID (Disease Ontology)
SNOMEDCT_US_2023_03_01:60657004
Cross Reference ID (Disease Ontology)
UMLS_CUI:C0019618
Exact Synonym (Disease Ontology)
chronic Histiocytosis X
Exact Synonym (Disease Ontology)
Hand Schuller Christian disease
HPO Human Phenotype ID (Human Phenotype Ontology)
HP:0100727
MeSH unique ID (MeSH (Medical Subject Headings))
D015614