chronic obstructive pulmonary disease
Information
- Disease name
- chronic obstructive pulmonary disease
- Disease ID
- DOID:3083
- Description
- "An obstructive lung disease that is a chronic and progressive disorder of small airways in the lungs and that is characterized by irreversible airflow obstruction, typically identified by reductions in quantitative spirometric indices, induced forced expiratory volume at 1 second (FEV1) and the ratio of FEV1 to forced vital capacity (less than 0.7 is diagnostic of COPD). Lung volume is increased and pulmonary hypertension may occur. The pathologic changes result in the disruption of the airflow in the bronchial airways. Signs and symptoms include shortness of breath, wheezing, productive cough and chest tightness. COPD is a consequence (an end result) of chronic bronchitis, emphysema or both." [url:https\://pubmed.ncbi.nlm.nih.gov/28513453/, url:https\://pubmed.ncbi.nlm.nih.gov/32745458/, url:https\://pubmed.ncbi.nlm.nih.gov/32800196/, url:https\://www.nhlbi.nih.gov/health-topics/copd]
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
| Genes | Mutation | Description | Source | Links |
|---|
| NCT ID | Status | Phase | Summary | Start date | Completion date |
|---|---|---|---|---|---|
| NCT04047810 | Active, not recruiting | Phase 1 | Mesenchymal Stem Cells in the Treatment of Subjects With Advance Chronic Obstructive Pulmonary Disease (COPD) | January 6, 2020 | December 2024 |
| NCT04136418 | Active, not recruiting | N/A | Predict&Prevent: Use of a Personalised Early Warning Decision Support System to Predict and Prevent Acute Exacerbations of COPD | October 7, 2020 | March 31, 2023 |
| NCT03451630 | Active, not recruiting | N/A | PCORI Integrated Care (IC) Models for Patient-Centered Outcomes | April 23, 2018 | August 31, 2024 |
| NCT05630599 | Active, not recruiting | Remote Assessment of Lung Disease and Impact on Physical and Mental Health | July 26, 2021 | March 31, 2023 | |
| NCT05037929 | Active, not recruiting | Phase 2 | A Study to Evaluate the Efficacy and Safety of Astegolimab in Participants With Chronic Obstructive Pulmonary Disease | October 5, 2021 | April 29, 2025 |
| NCT02627872 | Active, not recruiting | Clinical & Systems Medicine Investigations of Smoking-related Chronic Obstructive Pulmonary Disease | March 2007 | December 2025 | |
| NCT06325241 | Active, not recruiting | Validating the Use of Frailty Measurements to Predict Care & Quality of Life | December 12, 2022 | March 31, 2025 | |
| NCT05311306 | Active, not recruiting | REported Outcomes in COPD With Trixeo in Real worlD in Germany | March 15, 2022 | October 12, 2024 | |
| NCT05457868 | Active, not recruiting | Data Analysis for Drug Repurposing for Effective Alzheimer's Medicines (DREAM) - Salbutamol vs Long-acting Muscarinic Antagonists | February 1, 2021 | December 31, 2023 | |
| NCT04458038 | Active, not recruiting | N/A | Does Chronic Obstructive Lung Disease Influence the Cognitive Function | December 7, 2020 | December 31, 2023 |
| NCT04709562 | Active, not recruiting | N/A | Clinical Stabilization of Hypercapnia: NIPPV v HVNI | November 11, 2020 | December 22, 2023 |
| NCT03917914 | Active, not recruiting | Phase 3 | Preventing Adverse Cardiac Events in COPD | June 30, 2020 | March 2025 |
| NCT04456673 | Active, not recruiting | Phase 3 | Pivotal Study to Assess the Efficacy, Safety and Tolerability of Dupilumab in Patients With Moderate to Severe COPD With Type 2 Inflammation | July 6, 2020 | May 22, 2024 |
| NCT05076630 | Active, not recruiting | Air Pollution and Health of COPD Patients | October 12, 2021 | December 31, 2024 | |
| NCT05167201 | Active, not recruiting | N/A | Domiciliary Nasal High Flow and Patient Outcomes in Chronic Hypercapnic Respiratory Failure in the United Kingdom | March 28, 2022 | January 26, 2024 |
| NCT02802618 | Active, not recruiting | N/A | Interactive 3D Visualization Technique Used in Pulmonary Rehabilitation Programme in COPD | October 2013 | March 2024 |
| NCT05897944 | Active, not recruiting | Creating and Assessing a Voice Dataset for Automated Classification of Chronic Obstructive Pulmonary Disease | December 16, 2021 | December 30, 2023 | |
| NCT04140097 | Active, not recruiting | Predictors of Acute Exacerbation in Patients With COPD - an Observational Study | February 26, 2020 | April 30, 2026 | |
| NCT06326671 | Active, not recruiting | Phase 1 | A Trial to Assess the Bioequivalence of Generic Tiotropium Bromide Inhalation Powder and Reference Product in Healthy Adult Participants Under Fasting Conditions (Pilot) | February 28, 2024 | April 2024 |
| NCT04457843 | Active, not recruiting | The Mobile COPD Status Test (mCST) | August 21, 2020 | June 2023 | |
| NCT04415788 | Active, not recruiting | N/A | Inspiratory Muscle Training and COPD | May 1, 2021 | December 31, 2024 |
| NCT02967406 | Active, not recruiting | N/A | Impact of Lifestyle Modification on the Development of Dementia, Chronic Kidney Disease, Diabetes, Chronic Obstructive Pulmonary Disease, Cancers and Cardiovascular Disease in a Thai General Population | March 2016 | August 2027 |
| NCT04645732 | Active, not recruiting | N/A | Personalized Exercise Therapy and Self-management Support for Patients With Multimorbidity | November 1, 2021 | July 31, 2024 |
| NCT04217746 | Active, not recruiting | N/A | Effects of High Flow Nasal Cannula on Sputum Clearance in Acute Exacerbation of Chronic Obstructive Pulmonary Disease | February 1, 2020 | February 1, 2025 |
| NCT04053634 | Active, not recruiting | Phase 3 | Efficacy and Safety of Benralizumab in Moderate to Very Severe Chronic Obstructive Pulmonary Disease (COPD) With a History of Frequent Exacerbations | August 26, 2019 | August 21, 2025 |
| NCT01969344 | Active, not recruiting | Study of COPD Subgroups and Biomarkers | November 2010 | July 2024 | |
| NCT03726957 | Active, not recruiting | N/A | Exploring Respiratory Health Outcomes From Sustained Use of Efficient Cookstoves | November 1, 2014 | December 31, 2024 |
| NCT06160674 | Active, not recruiting | Vowel Segmentation for Classification of Chronic Obstructive Pulmonary Disease Using Machine Learning | November 28, 2023 | August 30, 2024 | |
| NCT05213611 | Active, not recruiting | REported Outcomes in COPD With Trixeo in Real worlD | August 11, 2022 | June 29, 2024 | |
| NCT04913389 | Active, not recruiting | Phase 3 | Acetazolamide to Prevent Impending Altitude-illness in Patients With COPD | June 1, 2021 | December 31, 2023 |
| NCT02743507 | Active, not recruiting | The Impact of Bundled Payments on Quality and Cost of Care | April 2016 | December 2024 | |
| NCT01318174 | Completed | Pulmonary Embolism in Exacerbations of Chronic Obstructive Pulmonary Disease | April 2011 | April 2013 | |
| NCT02074813 | Completed | N/A | Inspiratory Muscle Training During Pulmonary Rehabilitation in COPD | March 2014 | October 2016 |
| NCT02720822 | Completed | Phase 3 | Breathlessness Exertion and Morphine Sulphate | August 8, 2016 | December 20, 2019 |
| NCT02205255 | Completed | Phase 3 | BACE Trial Substudy 2 - FarmEc Substudy | August 1, 2014 | April 2020 |
| NCT02238327 | Completed | Longitudinal Evaluation of HIV-associated Lung Disease Phenotypes | September 2014 | March 2, 2020 | |
| NCT02108925 | Completed | N/A | Effect of Oxygen Supplementation During Exercise in Chronic Obstructive Pulmonary Disease Patients | April 2014 | March 2018 |
| NCT01597882 | Completed | Improving Monitoring of Patients Receiving Case Management | October 2012 | December 2013 | |
| NCT00935181 | Completed | Phase 4 | Respiratory Muscle Stretching in Chronic Obstructive Pulmonary Disease (COPD) | January 2006 | December 2008 |
| NCT05431426 | Completed | Phase 1 | PK of CHF6001 in Subjects With Mild, Moderate and Severe Renal Impairment vs. Healthy Volunteers | July 29, 2022 | December 27, 2022 |
| NCT01996319 | Completed | Phase 3 | Randomized, Double-blind, Placebo-controlled, Multicenter, Cross-over Study to Assess the Effects of a 3 Week Therapy Each With QVA149 Versus Placebo on Pulmonary Function and Average Physical Activity Levels in Patients With COPD. | April 2014 | February 2015 |
| NCT01448850 | Completed | Phase 2 | A Study to Evaluate the Efficacy of MEDI8968 in Chronic Obstructive Pulmonary Disease | November 2011 | February 2014 |
| NCT01146392 | Completed | An Investigation of the Past 10 Yrs Health Care for Primary Care Patients With Chronic Obstructive Pulmonary Disease | June 2010 | September 2011 | |
| NCT04149652 | Completed | N/A | Lung Elastrosonography in Diagnosis and Stratification of COPD and Fibrosis | April 5, 2019 | December 30, 2020 |
| NCT01522859 | Completed | N/A | Telehealth Monitoring in Chronic Obstructive Pulmonary Disease | August 2009 | June 2010 |
| NCT00745043 | Completed | N/A | Beta-Blocker in Chronic Obstructive Pulmonary Disease (COPD) Study | May 2005 | August 2007 |
| NCT02845752 | Completed | Phase 4 | The Effect of STIOLTO™ RESPIMAT® on Fatigue in Chronic Obstructive Pulmonary Disease | March 1, 2017 | August 6, 2018 |
| NCT00500526 | Completed | Phase 1/Phase 2 | Effects of Singing in Chronic Obstructive Pulmonary Disease | January 2005 | December 2007 |
| NCT04479969 | Completed | N/A | Enabling Independent Living by Expanding Access to Home-Based Pulmonary Rehabilitation | March 22, 2021 | July 30, 2021 |
| NCT02092675 | Completed | Endothelial Dysfunction and Chronic Obstructive Pulmonary Disease | March 2013 | May 2014 | |
| NCT02690038 | Completed | Phase 2 | Ig PRx in AECOPD: Pilot Study | September 2016 | November 20, 2019 |
| NCT01464567 | Completed | Phase 4 | Spontaneous Breathing Trials Using Pressure-Support or T-Tube in Chronic Obstructive Pulmonary Disease Patients Weaning Mechanical Ventilation | January 2012 | May 2016 |
| NCT01554072 | Completed | N/A | Home-based in Chronic Obstructive Pulmonary Disease | January 2012 | December 2012 |
| NCT01380652 | Completed | N/A | Vibration Training in Chronic Obstructive Pulmonary Disease (COPD)-Patients During a Three-week Rehabilitation | September 2010 | May 2011 |
| NCT00542282 | Completed | Vibration Response Imaging in Chronic Obstructive Pulmonary Disease and Asthma | November 2006 | August 2007 | |
| NCT01423227 | Completed | Phase 3 | Benefits and Costs of Home-based Pulmonary Rehabilitation in Chronic Obstructive Pulmonary Disease | October 2011 | May 2015 |
| NCT04474717 | Completed | N/A | Chronic Obstructive Pulmonary Disease in Combination With Atherosclerosis (Clinical and Biochemical Study) | November 15, 2020 | July 19, 2023 |
| NCT00837629 | Completed | Evaluation of Symbicort® Turbuhaler® (Budesonide/Formoterol) in Chronic Obstructive Pulmonary Disease (COPD) | February 2007 | September 2007 | |
| NCT02521532 | Completed | N/A | A 2 Week, Crossover Trial of Dietary Nitrate in Chronic Obstructive Pulmonary Disease | January 2015 | September 2015 |
| NCT02347774 | Completed | Phase 3 | Efficacy and Safety Trial of 12 Weeks of Treatment With Nebulized SUN-101 in Patients With COPD (GOLDEN-4) | February 2015 | December 2015 |
| NCT02787863 | Completed | Phase 4 | Clinical and Immunological Efficiency of Bacterial Vaccines at Adult Patients With Bronchopulmonary Pathology | September 6, 2012 | December 31, 2016 |
| NCT01478646 | Completed | N/A | The Effect of Reflective Breathing Therapy Compared With Conventional Breathing Therapy in Patients With Chronic Obstructive Pulmonary Disease (COPD) III-IV | August 2011 | November 2011 |
| NCT03244137 | Completed | Effects of Pulmonary Rehabilitation on Cognitive Function in Patients With Severe to Very Severe Chronic Obstructive Pulmonary Disease | September 4, 2017 | December 1, 2019 | |
| NCT03137524 | Completed | N/A | Fan Therapy in COPD Patients | May 24, 2017 | July 26, 2017 |
| NCT02972476 | Completed | Phase 4 | Microbiome Use to Stratify Use of Inhaled Corticosteroids: MUSIC Trial | December 2016 | July 22, 2019 |
| NCT04790617 | Completed | N/A | ENCOMPASS: Expansion Study B, RCT | March 1, 2021 | November 10, 2023 |
| NCT05569421 | Completed | Phase 1 | A Study to Assess the Total Systemic Exposure Bioequivalence of of Budesonide, Glycopyrronium, and Formoterol Delivered by BGF MDI HFO Compared With BGF MDI HFA | October 11, 2022 | April 14, 2023 |
| NCT01599871 | Completed | Phase 3 | Low-dose Theophylline as Anti-inflammatory Enhancer in Severe Chronic Obstructive Pulmonary Disease | January 2011 | September 2016 |
| NCT01826669 | Completed | N/A | Chest Wall Muscle Stretching and Acute Effects in Chronic Obstructive Pulmonary Disease | May 2011 | December 2011 |
| NCT00568100 | Completed | N/A | Effect of Pressure Support Ventilation and Neurally Adjusted Ventilatory Assist (NAVA) in Chronic Obstructive Pulmonary Disease (COPD) Patients | April 2010 | November 2014 |
| NCT02248064 | Completed | N/A | Auto-titrating Oxygen in Chronic Respiratory Failure | July 2014 | November 2015 |
| NCT02045394 | Completed | Epidemiology and Diagnosis of Haemoptysis: a Multicenter Study | June 2013 | ||
| NCT01057797 | Completed | Phase 2 | Nurse Managed Upper Body Strength Training in Chronic Obstructive Pulmonary Disease (COPD) | September 2003 | January 2009 |
| NCT00393458 | Completed | Phase 3 | Efficacy, Safety, and Tolerability of Once Daily Indacaterol in Chronic Obstructive Pulmonary Disease (COPD) Using Formoterol Twice Daily as Active Control | October 2006 | July 2008 |
| NCT00379028 | Completed | Phase 4 | Airway Clearance Study | September 2006 | July 2007 |
| NCT03804138 | Completed | Immune Damage and Vaccination in COPD Patients | October 9, 2018 | February 3, 2023 | |
| NCT02519608 | Completed | Phase 2 | ComparisoN of ticAgrelor vs. Clopidogrel in endoTHeliAl Function of COPD patieNts | September 2015 | January 2017 |
| NCT01865500 | Completed | Phase 4 | Two Different Dosages of Nebulized Steroid Versus Parenteral Steroid in the Management of COPD Exacerbations | January 2013 | May 2013 |
| NCT02331940 | Completed | N/A | Tiotropium Respimat Versus HandiHaler on SaO2 and Sleep in COPD Patients | March 2010 | September 2014 |
| NCT00457301 | Completed | Using Health-related Quality of Life (HRQL) in Routine Clinical Care | July 2005 | May 2008 | |
| NCT01151618 | Completed | N/A | Evaluating Forced Oscillation Technique (FOT) in Abolishing Flow Limitation | June 2010 | September 2010 |
| NCT01045213 | Completed | Phase 3 | Integrated Care Program for Chronic Obstructive Pulmonary Disease | October 2008 | June 2009 |
| NCT03105999 | Completed | Observational Study On The Characterization Of 24-Hour Symptoms In Patients With COPD | February 1, 2016 | June 7, 2018 | |
| NCT01263340 | Completed | Characterisation of People With COPD | December 2010 | April 2013 | |
| NCT00879281 | Completed | N/A | Action Plan to Enhance Self-management and Early Detection of Exacerbations in Chronic Obstructive Pulmonary Disease (COPD) Patients | December 2008 | December 2010 |
| NCT03102970 | Completed | Pain Assessment in Patients With Chronic Obstructive Pulmonary Disease (COPD) Exacerbations. | December 2015 | April 5, 2018 | |
| NCT01792271 | Completed | N/A | Sustained Effects of Hypertonic Saline on Mucociliary Clearance in Subjects With Chronic Bronchitis | February 2013 | May 2016 |
| NCT01470274 | Completed | Safety of the CO-rebreathing Method in Stable Coronary Artery Disease and COPD Patients | November 2011 | February 2012 | |
| NCT02812979 | Completed | N/A | Evaluation of the Effectiveness of the Nebulization Bronchodilators Under High Nasal Flow Humidified | June 2016 | April 27, 2018 |
| NCT03174210 | Completed | N/A | Effects of Supplemental Oxygen Delivered by a Portable Oxygen Concentrator Compared to a Liquid Oxygen Device in COPD | May 2, 2017 | September 15, 2017 |
| NCT00094562 | Completed | Phase 2 | A Fish Oil Supplement to Maintain Body Weight in Patients With Disease-Related Weight Loss | June 2004 | September 2007 |
| NCT01812031 | Completed | N/A | Benefits Study of Respiratory-gated PET Acquisition in Lung Disease | August 2009 | February 2015 |
| NCT00875719 | Completed | N/A | Oxygen Portable Concentrator During Exercises in Patients With COPD | February 2009 | February 2011 |
| NCT04074499 | Completed | The Risk of Falling in Patients With Chronic Obstructive Pulmonary Disease | August 31, 2019 | December 3, 2019 | |
| NCT01867762 | Completed | Phase 2 | An Effectiveness and Safety Study of Inhaled JNJ 49095397 (RV568) in Patients With Moderate to Severe Chronic Obstructive Pulmonary Disease | September 9, 2013 | September 1, 2014 |
| NCT05102305 | Completed | A Multi-center,Prospective, OS to Evaluate the Effectiveness of 'NAC' Nebulizer Therapy in COPD (NEWEST) | September 9, 2021 | November 29, 2022 | |
| NCT00845728 | Completed | Phase 3 | Exacerbation Study | March 2009 | July 2012 |
| NCT01110252 | Completed | N/A | Safety Study of Cell Therapy to Treat Chronic Obstructive Pulmonary Disease | May 2009 | November 2011 |
| NCT02842463 | Completed | 6-minute Stepper Test and Pulmonary Rehabilitation in Patients With Chronicle Obstructive Pulmonary Disease | July 2016 | December 2023 | |
| NCT00758706 | Completed | Phase 2 | A Phase IIa Study Assessing the Effects of AZD1236 on Biomarkers in Chronic Obstructive Pulmonary Disease (COPD) Patients | September 2008 | May 2009 |
| NCT02419872 | Completed | Study in Patients' With Persistent Asthma and Chronic Obstructive Pulmonary Disease | May 31, 2015 | April 7, 2017 | |
| NCT00852020 | Completed | N/A | Safety, Tolerance and Efficacy of an Oral Nutritional Supplement in Chronic Heart Failure and Chronic Obstructive Pulmonary Disease Patients | April 2009 | April 2011 |
| NCT04928417 | Completed | Exacerbations and Their Outcomes International (EXACOS International) | November 26, 2021 | November 30, 2022 | |
| NCT05256303 | Completed | N/A | Rural Hospital-Level Care at Home for Acutely Ill Adults | February 16, 2022 | January 17, 2024 |
| NCT00515606 | Completed | Phase 3 | Noninvasive Positive Pressure Ventilation Using Helium:Oxygen Versus Air:Oxygen in Acute Respiratory Failure in Chronic Obstructive Pulmonary Disease Patients Exposed to Sulfur Mustard | February 2007 | June 2007 |
| NCT03077152 | Completed | Patient Factors Associated With Prescription of Antibiotics for Inappropriate Indication in Patients With AECOPD | January 1, 2017 | September 1, 2018 | |
| NCT01096173 | Completed | Determination of the in Vitro Effects of Cationic Airway Lining Modulators (CALM) on Chronic Obstructive Pulmonary Disease (COPD) Sputum | April 2010 | October 2010 | |
| NCT03943030 | Completed | N/A | Cardiovascular Effects of Pulmonary Rehabilitation in COPD | February 11, 2019 | July 18, 2023 |
| NCT03546907 | Completed | Phase 2 | Proof-of-Concept Study to Assess the Efficacy, Safety and Tolerability of SAR440340 (Anti-IL-33 mAb) in Patients With Moderate-to-severe Chronic Obstructive Pulmonary Disease (COPD) | July 16, 2018 | February 21, 2020 |
| NCT01119950 | Completed | Phase 2 | Efficacy and Safety of NVA237 in Patients With Chronic Obstructive Pulmonary Disease (COPD) | April 2010 | December 2010 |
| NCT01112943 | Completed | N/A | Acupuncture Combined With Pulmonary Rehabilitation: Are There Additional Benefits? | July 2007 | January 2009 |
| NCT03848819 | Completed | N/A | Effect of Portable NIV on Operational Chest Wall Volumes in COPD | July 1, 2019 | February 29, 2020 |
| NCT01259245 | Completed | N/A | Effectiveness of Incorporating Tai Chi in Pulmonary Rehabilitation Program for Chronic Obstructive Pulmonary Disease Patients in Primary Health Care | March 2011 | May 2012 |
| NCT01091493 | Completed | Phase 4 | Antibiotic or Not in Non-purulent Exacerbations of COPD: a Trial of Security and Efficacy | July 2010 | July 5, 2018 |
| NCT05668247 | Completed | N/A | The Effects on Sleep qualıty and fatıgue Level of Foot Bath | May 5, 2017 | April 5, 2018 |
| NCT02196077 | Completed | Phase 2 | Efficacy and Safety Study of PT009, PT008, and PT005 in Subjects With Moderate to Severe Chronic Obstructive Pulmonary Disease (COPD) | August 1, 2014 | March 1, 2015 |
| NCT04241510 | Completed | N/A | Effects of Kinesio Taping Techniques in COPD Patients | April 20, 2022 | October 31, 2022 |
| NCT04542057 | Completed | Phase 3 | A Phase 3 Trial to Evaluate the Safety and Efficacy of Ensifentrine in Patients With COPD | September 22, 2020 | July 6, 2022 |
| NCT05263349 | Completed | Dream Analysis in COPD Patients | July 1, 2022 | October 15, 2023 | |
| NCT05918731 | Completed | N/A | Self-management in Chronic Obstructive Pulmonary Disease (COPD) Patients Compared to Usual Care | April 1, 2020 | March 30, 2021 |
| NCT02171377 | Completed | N/A | Quadricipital Electrical Stimulation in COPD Patients Rehabilitation | August 2010 | December 2013 |
| NCT00844116 | Completed | N/A | Efficacy of "On Line" Telematic Spirometry | January 2009 | December 2011 |
| NCT02760329 | Completed | Observational Study of Obstructive Lung Disease (NOVELTY) | July 25, 2016 | May 31, 2023 | |
| NCT04141891 | Completed | N/A | Advancing Understanding of Transportation Options | December 12, 2019 | December 21, 2023 |
| NCT01102712 | Completed | N/A | Bronchoscopic Thermal Vapor Ablation (BTVA) for Lung Volume Reduction | November 2009 | August 2011 |
| NCT03243994 | Completed | N/A | Small Intestinal Absorption in Patients With Chronic Obstructive Pulmonary Disease and Cor Pulmonale | February 1, 2016 | October 1, 2016 |
| NCT02012101 | Completed | N/A | Non-invasive Mechanical Ventilation as a Rescue Therapy to Relieve Dyspnea in Patients With Stable Severe COPD | March 2013 | April 2014 |
| NCT03310164 | Completed | Lung and Gut Microbiome in Chronic Obstructive Pulmonary Disease | June 15, 2014 | February 15, 2016 | |
| NCT01554774 | Completed | Non-invasive Assessment of Pulmonary Vascular Resistance in Elderly Patients With Chronic Obstructive Pulmonary Disease | March 2012 | July 2012 | |
| NCT00507949 | Completed | Phase 2 | Study to Evaluate the Effect of Megestrol Acetate in Severe Chronic Obstructive Pulmonary Disease With Loss of Weight | October 2006 | September 2009 |
| NCT00005537 | Completed | Genetics of Airway Responsiveness and Lung Function | July 1997 | June 2002 | |
| NCT05230927 | Completed | Cognitive Impairment, Frailty and Rehabilitative Outcome in Older Patients Affected by Cardiorespiratory Disease | April 21, 2020 | December 23, 2022 | |
| NCT03739879 | Completed | N/A | Effectivity of Inspiratory Muscle Trainer in the Chronic Obstructive Pulmonary Disease Rehabilitation Program | September 1, 2017 | April 30, 2018 |
| NCT02467452 | Completed | Phase 3 | Non Inferiority of Fixed Combination of Beclomethasone Dipropionate (BDP) + Formoterol Fumarate (FF) + Glycopyrronium Bromide (GB) Versus Combination of Fluticasone Furoate (FlF)/Vilanterol (VI) + Tiotropium Bromide in Chronic Obstructive Pulmonary Disease (COPD) | May 2015 | January 2017 |
| NCT00725673 | Completed | Case Control Study: Determinants of Osteoporosis in GOLD II COPD Patients. | September 2007 | June 2009 | |
| NCT04333901 | Completed | Compliance of Long-term Home Non-invasive Ventilation for Patients With Chronic Obstructive Pulmonary Disease | December 16, 2019 | December 31, 2022 | |
| NCT00974246 | Completed | Phase 4 | The Effect on Depressive Symptoms in ECF Residents With COPD | October 2009 | July 2011 |
| NCT02988388 | Completed | Lung Tissue Research Consortium | February 23, 2017 | February 21, 2019 | |
| NCT02086084 | Completed | N/A | ECCO2R as an Adjunct to NIV in AECOPD | December 1, 2015 | December 31, 2020 |
| NCT01493544 | Completed | Prevalence Study and Regular Practice Among General Practitioners in Populations at Risk of Chronic Obstructive Pulmonary Disease (COPD) in Latin America | February 2012 | October 2012 | |
| NCT02493790 | Completed | Cognitive Dysfunction in COPD Patients : Role in the Performance of Cognitive-motor Dual Task Situation? | October 2014 | August 2016 | |
| NCT05922241 | Completed | N/A | Comparative Effects of Costophrenic Assisted Cough and Anterior Chest Compression Technique in COPD Patients | June 15, 2023 | December 5, 2023 |
| NCT01911364 | Completed | Phase 3 | Efficacy of Fixed Combination of Beclometasone + Formoterol + Glycopyrrolate in Chronic Obstructive Pulmonary Disease | January 2014 | March 2016 |
| NCT04479930 | Completed | Phase 2/Phase 3 | Effects of an mHealth Web-Based Platform (HappyAir) on Adherence to a Maintenance Program After Pulmonary Rehabilitation in Patients With Chronic Obstructive Pulmonary Disease | December 2015 | May 2017 |
| NCT02147015 | Completed | N/A | Personalized Variable Versus Fixed Dose Glucocorticoid Therapy in AECOPD | June 2014 | April 2018 |
| NCT02014155 | Completed | N/A | Inspiratory Muscle Training and Respiratory Electromyographic Activity in COPD | August 2013 | January 1, 2015 |
| NCT00989456 | Completed | N/A | Well Being and Rehabilitation in Chronically Ill Patients: Structured Patient Education and Physical Exercise | September 2009 | April 2013 |
| NCT03957759 | Completed | Early Signs of Altitude Illness in Patients With COPD | May 20, 2019 | August 8, 2021 | |
| NCT02552160 | Completed | DETECT-Register DocumEnTation and Evaluation of a COPD Combination Therapy | September 24, 2015 | December 31, 2017 | |
| NCT01364181 | Completed | Phase 3 | The Impact of Udenafil on Exercise Capacity in Severe Chronic Obstructive Pulmonary Disease (COPD) Patients | March 2010 | May 2011 |
| NCT00736268 | Completed | N/A | Coping Skills for Patients With Chronic Obstructive Pulmonary Disease (COPD) and Their Caregivers | August 2008 | |
| NCT00784095 | Completed | N/A | Outlook Quality of Life Intervention | December 2008 | May 2009 |
| NCT04775394 | Completed | N/A | Activation of Apoptosis-related Receptors on Alveolar Macrophages | January 1, 2021 | July 21, 2023 |
| NCT01148719 | Completed | N/A | Triage of Reduced Exercise Tolerance in Frail Elderly | May 2010 | September 2012 |
| NCT01079221 | Completed | N/A | Effects of Knee-extensor Exercise Training in Chronic Obstructive Pulmonary Disease (COPD) Patients | February 2009 | December 2012 |
| NCT04301245 | Completed | Profile of COPD Patients Refusing Educational Program in Pulmonary Rehabilitation and Impact on the Benefits | February 28, 2020 | April 10, 2020 | |
| NCT02885103 | Completed | N/A | Combination of NHF and Nebulizer on Lung Function in COPD | August 2016 | November 2017 |
| NCT00556816 | Completed | N/A | Chronic Obstructive Pulmonary Disease (COPD) Outpatient on Demand Clinic | September 2007 | October 2011 |
| NCT02888886 | Completed | N/A | Role of Systemic Inflammation in Increase of Cardio-vascular Risk in Chronic Obstructive Pulmonary Disease | July 2007 | November 2015 |
| NCT01475292 | Completed | Phase 2 | A Study to Investigate How Safe and Well Tolerated RV568 is in Patients With Chronic Obstructive Pulmonary Disease (COPD) | November 2011 | April 2012 |
| NCT00863616 | Completed | N/A | High Frequency Chest Wall Oscillation in Chronic Obstructive Pulmonary Disease (COPD) | August 2006 | October 2007 |
| NCT00440687 | Completed | Phase 4 | Withdrawal of Inhaled Corticosteroids in Patients With COPD in Primary Care | January 2001 | March 2004 |
| NCT02873780 | Completed | Comparison of 3-Minute Step Test (3MStepT) and 6-Minute Walk Test (6MWT) in COPD Patients | July 2016 | September 2016 | |
| NCT02084758 | Completed | N/A | Nitrate Supplementation in Chronic Obstructive Pulmonary Disease (COPD) | September 2015 | October 2016 |
| NCT00981851 | Completed | N/A | Interaction in Chronic Obstructive Pulmonary Disease Experiment | September 2009 | May 2011 |
| NCT01325948 | Completed | Cross-sectional Study to Investigate the Effects of Chronic Obstructive Pulmonary Disease on Daily Life Activities | March 2011 | June 2011 | |
| NCT05459740 | Completed | Self-management Behaviors and Resilience Among Chronic Obstructive Pulmonary Disease Patients | February 1, 2020 | January 30, 2021 | |
| NCT00206167 | Completed | Phase 3 | A Comparison of Symbicort® pMDI 2 x 160/4.5 μg Bid and 2 x 80/4.5 μg Bid With Formoterol Turbuhaler® 2 x 4.5 μg Bid and Placebo in Patients With COPD | April 2005 | September 2007 |
| NCT00677690 | Completed | Phase 3 | Neuromuscular Electrical Stimulation in Chronic Obstructive Pulmonary Disease (COPD) | January 2007 | January 2009 |
| NCT01490125 | Completed | Phase 3 | The Effect of QVA149 on Patient Reported Dyspnea in Moderate to Severe Chronic Obstructive Pulmonary Disease (COPD) | October 2011 | August 2012 |
| NCT00316992 | Completed | Phase 4 | Safety of Ramelteon in Subjects With Chronic Obstructive Pulmonary Disease | April 2006 | November 2006 |
| NCT02205242 | Completed | Phase 3 | BACE Trial Substudy 1 - PROactive Substudy | September 2014 | April 2020 |
| NCT01013142 | Completed | Phase 1 | Evaluate the Safety of MN-221 in Subjects With Stable Moderate to Severe Chronic Obstructive Pulmonary Disease (COPD) | November 2009 | March 2010 |
| NCT01013922 | Completed | A Descriptive Study to Explore Certain Characteristics of Patients at Risk for Chronic Obstructive Pulmonary Disease (COPD) in a Primary Care Setting | October 2009 | March 2010 | |
| NCT02956213 | Completed | N/A | Indoor Air Quality and Respiratory Symptoms in Former Smokers | November 2016 | June 2019 |
| NCT01509677 | Completed | Phase 3 | Trial to Assess the Anti-inflammatory Effects of Roflumilast in Chronic Obstructive Pulmonary Disease | February 1, 2012 | February 1, 2016 |
| NCT04260178 | Completed | N/A | Education-Based İntervention Program for Persons With Chronic Obstructive Pulmonary Disease (EBIPCOPD) | March 4, 2019 | June 27, 2019 |
| NCT01750489 | Completed | N/A | Muscle Dysfunction in Patients With Chronic Obstructive Lung Disease (COPD): the Role of Sympathetic Activation | August 2011 | |
| NCT02278237 | Completed | N/A | Pre/Post Pilot Test of Video Module Education | November 2014 | October 2015 |
| NCT01034982 | Completed | Phase 1 | AZD9668 Relative Bioavailability | November 2009 | December 2009 |
| NCT01219946 | Completed | A Study for the Assessment of the Words Used by Patients and Physicians to Express the Symptoms of Chronic Obstructive Pulmonary Disease (COPD) | October 2010 | March 2011 | |
| NCT02447575 | Completed | N/A | Detecting Errors In Using Metered Dose Inhalers (MDI) Among Asthma And Chronic Obstructive Pulmonary Disease (COPD) Patients | February 2015 | July 2019 |
| NCT00990132 | Completed | Phase 2/Phase 3 | Home Mechanical Ventilation vs Home Oxygen Therapy in COPD | October 2009 | April 2016 |
| NCT01014338 | Completed | Phase 4 | Angiotensin-converting Enzyme (ACE)-Inhibition and Mechanisms of Skeletal Muscle Weakness in Chronic Obstructive Pulmonary Disease (COPD) | October 2009 | September 2012 |
| NCT03169270 | Completed | N/A | Muscular Training-induced Changes in COPD | November 2005 | May 2007 |
| NCT01320930 | Completed | N/A | Rehabilitation in Subjects With Moderate Chronic Obstructive Pulmonary Disease (COPD) | January 2007 | March 2011 |
| NCT01556139 | Completed | N/A | Effectiveness of Respiratory Muscle Training by Spirotiger in Chronic Patients | June 2011 | February 2016 |
| NCT00869544 | Completed | Pneumocystis in Pathogenesis of HIV-associated Emphysema | August 2007 | July 2013 | |
| NCT02596087 | Completed | N/A | Improving Quality by Maintaining Accurate Problems in the EHR | April 2016 | |
| NCT04084405 | Completed | N/A | Effect of Inspiratory Muscle Training During Pulmonary Rehabilitation on Balance in COPD Patients | January 1, 2019 | November 15, 2019 |
| NCT00000571 | Completed | Phase 3 | Trial of Inspiratory Muscle Rest and Exercise in Chronic Obstructive Lung Disease | February 1986 | |
| NCT04448236 | Completed | N/A | Effect of Blood Flow Restriction Resistance Exercises in COPDAE In-patient Rehabilitation | June 10, 2020 | December 9, 2020 |
| NCT03077386 | Completed | N/A | Enhancing Community Health Through Patient Navigation, Advocacy and Social Support | June 8, 2018 | March 3, 2024 |
| NCT01544543 | Completed | Validation of HealthCare Standards in Chronic Obstructive Pulmonary Disease | February 2010 | ||
| NCT05572333 | Completed | Phase 2 | Clinical Trial to Investigate the Safety and Tolerability of EP395 in Patients With COPD | November 22, 2022 | November 24, 2023 |
| NCT01085045 | Completed | Phase 2 | Study to Evaluate the Efficacy, Safety and Pharmacokinetics of PT001, PT003, and PT005 Following Chronic Dosing (7 Days) in Patients With Moderate to Very Severe Chronic Obstructive Pulmonary Disease (COPD) | March 2010 | November 2010 |
| NCT00783107 | Completed | Phase 1 | Aerosol Cyclosporine in Chronic Obstructive Pulmonary Disease (COPD) | October 2007 | September 2009 |
| NCT00884299 | Completed | N/A | Nutritional Enhancement in Chronic Obstructive Pulmonary Disease (COPD) | January 2004 | April 2009 |
| NCT03457103 | Completed | Phase 2 | Capnometry-Assisted Breathing Training for COPD | June 16, 2015 | August 2, 2019 |
| NCT01083238 | Completed | Phase 1 | This Study Will Investigate How Food and Age Effect the Way the Body Handles the AZD5069 Drug Given as a Oral Dose | February 2010 | July 2010 |
| NCT01108913 | Completed | Phase 2 | Study to Evaluate Safety and Efficacy of Inhaled Bimosiamose for the Treatment of Patients With Moderate to Severe Chronic Obstructive Pulmonary Disease (COPD) | ||
| NCT00870857 | Completed | Prevalence and Pathogenesis of Lung Disease in a Large HIV Cohort-coordinating Center | January 2009 | August 2016 | |
| NCT01226342 | Completed | N/A | Transcutaneous Electrical Muscle Stimulation In Chronic Obstructive Pulmonary Disease (COPD) | January 2009 | October 2009 |
| NCT04815499 | Completed | N/A | Effects of a Food Supplement on Quality of Life in Patients With Chronic Obstructive Pulmonary Disease. | January 14, 2020 | November 3, 2022 |
| NCT00951782 | Completed | Phase 2/Phase 3 | Deep High-Frequency Repetitive Transcranial Magnetic Stimulation for Smoking Cessation | October 2009 | May 2013 |
| NCT01974219 | Completed | HIV-related Accelerated Aging of the Airway Epithelium | December 23, 2013 | February 14, 2019 | |
| NCT03055923 | Completed | EXhaled Hydrogen Peroxide As a Marker of Lung diseasE (EXHALE) Pilot Study. | November 14, 2016 | April 10, 2018 | |
| NCT01381367 | Completed | Phase 4 | PPSV23 Pneumococcal Vaccine in Chronic Obstructive Pulmonary Disease (COPD) | February 2009 | June 2011 |
| NCT02986321 | Completed | Phase 2 | A 24-wk Dose Ranging Study to Evaluate the Efficacy and Safety of 4 Doses of a New PDE4 Inhibitor in Patients With COPD | December 15, 2016 | January 9, 2018 |
| NCT03443505 | Completed | NRD to Predict COPD Exacerbations at Home | February 13, 2018 | June 6, 2019 | |
| NCT02371629 | Completed | Phase 4 | A Study of the Efficacy and Safety of NVA237 in Patients With Moderate to Severe COPD | June 24, 2015 | November 16, 2016 |
| NCT02220387 | Completed | Molecular, Cytological Features and Genetic Susceptibility of COPD Attributable to Different Environmental Exposures | August 2014 | September 2014 | |
| NCT03887364 | Completed | N/A | Icing and Airflow Stimulation in Obstructive Lung Diseases | February 2, 2018 | July 1, 2018 |
| NCT02823795 | Completed | N/A | The Supporting Patient Activation in Transition to Home Intervention | September 2016 | September 2018 |
| NCT01551316 | Completed | Phase 1 | Safety Study to Evaluate MN-221 in Chronic Obstructive Pulmonary Disease (COPD) Patients | March 2012 | May 2012 |
| NCT00605891 | Completed | Phase 2 | Dose Finding Study of CHF 4226 for Treating Patients With COPD | October 2006 | June 2007 |
| NCT01329029 | Completed | Phase 4 | Roflumilast in Chronic Obstructive Pulmonary Disease (COPD) Patients Treated With Fixed Combinations of Long-acting β2-agonists (LABA) and Inhaled Glucocorticosteroid (ICS) | May 2011 | May 2014 |
| NCT04834037 | Completed | N/A | Effect of Provision of Information and Supportive Nursing Care: A Randomised Controlled Trial | September 1, 2019 | December 30, 2020 |
| NCT01942499 | Completed | N/A | Community-Based Maintenance Exercise Program for COPD | November 2012 | July 2018 |
| NCT01173328 | Completed | N/A | Effects of Pursed-lip Breathing on Exercise Tolerance and Dynamic Hyperinflation in COPD | March 2007 | October 2009 |
| NCT00974220 | Completed | N/A | Effect of Inhaled Fentanyl on Dyspnea and Exercise Tolerance in Chronic Obstructive Pulmonary Disease (COPD) | January 2010 | December 2010 |
| NCT03159091 | Completed | Phase 4 | Clinical Trial of Efficacy and Safety of Rengalin in the Treatment of Cough in Patients With Chronic Obstructive Pulmonary Disease | June 16, 2017 | April 25, 2019 |
| NCT01019538 | Completed | Pre-flight Titration of Supplemental Oxygen | December 2008 | April 2010 | |
| NCT02343055 | Completed | N/A | COPE With COPD Trial | October 2011 | January 2015 |
| NCT03084796 | Completed | Phase 2 | A 6-week Dose Ranging Study of CHF 5259 pMDI in Subjects With Chronic Obstructive Pulmonary Disease | July 28, 2017 | June 6, 2018 |
| NCT02347566 | Completed | N/A | Physical Activity Enhancing Programme in COPD | February 2015 | March 30, 2017 |
| NCT01782768 | Completed | N/A | Comparative Effects of Different Noninvasive Ventilation Mode on Neural Respiratory Drive in Recovering AECOPD Patients | January 2013 | April 2013 |
| NCT04387318 | Completed | N/A | Inspiratory Muscle Training and Neuromuscular Electrical Stimulation in Chronic Obstructive Pulmonary Disease | October 1, 2019 | March 10, 2023 |
| NCT01693003 | Completed | Phase 4 | Indacaterol Versus Tiotropium on Dynamic Hyperinflation in COPD | March 2013 | October 2013 |
| NCT01141452 | Completed | Real-life Effectiveness and Cost-effectiveness of Qvar Versus FP and BDP in the Management of COPD | January 2001 | July 2007 | |
| NCT00880490 | Completed | Phase 1/Phase 2 | Study to Evaluate the Safety and Efficacy of Inhaled PT005 in Patients With Chronic Obstructive Pulmonary Disease (COPD) | November 2008 | May 2009 |
| NCT00949975 | Completed | Phase 2 | A Dose Range Finding Study to Evaluate the Efficacy and Safety of AZD9668 Administered Orally at Three Dose Levels to Patients With Chronic Obstructive Pulmonary Disease (COPD) on Treatment With Tiotropium | July 2009 | August 2010 |
| NCT00624286 | Completed | Phase 3 | Efficacy and Safety of Indacaterol in Patients With Chronic Obstructive Pulmonary Disease (COPD) | February 2008 | July 2008 |
| NCT00338507 | Completed | Phase 2 | Phase 2 Study - Erdosteine in Patients With CB/COPD | March 2006 | |
| NCT00000565 | Completed | Phase 3 | Clinical Study of Intermittent Positive Pressure Breathing (IPPB) | November 1976 | |
| NCT01369810 | Completed | Outcome Study Following Reimbursement Changes in the Use of Fixed Combination Inhalers in Patients With Asthma or Chronic Obstructive Pulmonary Disease | July 2011 | September 2013 | |
| NCT02068456 | Completed | Post Marketing Surveillance of Roflumilast in Korea | September 18, 2012 | April 26, 2017 | |
| NCT01762917 | Completed | Influence of Bag Volume Variation on the Reproducibility of Inert Gas Rebreathing | September 2007 | December 2010 | |
| NCT02471235 | Completed | N/A | Short-course Out-patient Pulmonary Rehabilitation and COPD Exacerbations | July 2015 | November 2018 |
| NCT04790604 | Completed | N/A | ENCOMPASS: Expansion Study A, RCT | January 22, 2021 | July 3, 2023 |
| NCT03201198 | Completed | N/A | Active for Life: Chronic Obstructive Pulmonary Disease | July 27, 2017 | January 31, 2023 |
| NCT00005282 | Completed | Prospective Evaluation of Airways Reactivity | December 1981 | November 1997 | |
| NCT01217710 | Completed | Phase 2 | Promoting Physical Activity in Chronic Obstructive Pulmonary Disease (COPD) Through New Technology and Health Coaching | April 2012 | January 2014 |
| NCT00909779 | Completed | Phase 3 | Safety Study of Arformoterol Tartrate Inhalation Solution in Chronic Obstructive Pulmonary Disease (COPD) Subjects | June 2009 | June 2012 |
| NCT03214458 | Completed | N/A | Effects of Nasal High-flow Oxygen in Patients With an Exacerbation of Chronic Obstructive Pulmonary Disease (COPD) | July 20, 2017 | April 18, 2018 |
| NCT01273259 | Completed | Phase 2 | Study of Dehydroepiandrosterone (DHEA) in Respiratory Pulmonary Hypertension in Adults | May 6, 2008 | June 5, 2015 |
| NCT00940355 | Completed | N/A | Secondary Prevention of Problems in Health Status in Patients With Chronic Obstructive Pulmonary Disease (COPD) | September 2007 | October 2009 |
| NCT00005292 | Completed | Alpha1-antitrypsin Deficiency Registry | September 1988 | November 1999 | |
| NCT01196832 | Completed | Role of Fibrocytes in Chronic Obstructive Pulmonary Disease | March 11, 2011 | May 31, 2016 | |
| NCT01089127 | Completed | Phase 3 | Efficacy and Safety of Different Doses of Indacaterol in Chronic Obstructive Pulmonary Disease (COPD) | March 2010 | July 2010 |
| NCT03177850 | Completed | Phase 4 | Effect of Acetazolamide on Sleep Related Breathing Disturbances in Patients With Respiratory Disease at Altitude | May 24, 2017 | August 2, 2018 |
| NCT01307189 | Completed | Phase 4 | Effects of Tiotropium on Walking Capacity in Patients With COPD | April 2005 | August 2010 |
| NCT03004716 | Completed | Telemonitoring in Pulmonary Rehabilitation: Validity of a Remote Pulse Oxymetry System | January 2017 | March 2017 | |
| NCT00611520 | Completed | Symbicort in Chronic Obstructive Pulmonary Disease | September 2005 | ||
| NCT02964117 | Completed | Associations Between Air Pollutants Exposures and Respiratory System Study | November 2014 | January 2016 | |
| NCT00005717 | Completed | Medication Adherence in COPD--A Self-Regulation Study | August 1990 | July 1995 | |
| NCT04964037 | Completed | Analysis of Relationship Between Metabolic Biomarkers and Efficacy of Glucocorticoid in AECOPD | January 2, 2017 | March 30, 2018 | |
| NCT04726384 | Completed | Physical Activity Level of Patients With COPD During Pulmonary Rehabilitation | October 1, 2020 | January 8, 2021 | |
| NCT02115412 | Completed | Validation of Medication Non-adherence Model (UK) | July 2014 | December 2015 | |
| NCT00064415 | Completed | Phase 3 | To Evaluate the Long-term Safety of (R,R)-Formoterol in Subjects With COPD | June 2002 | December 2004 |
| NCT01922271 | Completed | Phase 4 | Efficacy of NVA237 Compared to Tiotropium in Patients With Chronic Obstructive Pulmonary Disease (COPD) | August 2013 | January 2014 |
| NCT01694732 | Completed | Phase 3 | Efficacy of Varenicline on Smoking Cessation at the Acute Phase of an Exacerbation of Chronic Obstructive Pulmonary Disease | August 2012 | November 2015 |
| NCT01832961 | Completed | N/A | Acute Effects of a Flutter Device in COPD | April 2013 | December 2013 |
| NCT03365713 | Completed | GECo: Implementation and Effectiveness of COPD Case-Finding in Low and Middle Income Countries | January 8, 2018 | March 9, 2020 | |
| NCT01180439 | Completed | N/A | Patient-Ventilator Interactions in Chronic Obstructive Pulmonary Diseases (COPD) Under Non-Invasive Ventilation | October 2009 | August 2010 |
| NCT06240936 | Completed | N/A | Active Cycle of Breathing Techniques With and Without Acapella in COPD Patients | February 15, 2024 | April 15, 2024 |
| NCT00206154 | Completed | Phase 3 | A Comparison of Symbicort® pMDI 2 x 160/4.5 μg Bid and Symbicort® pMDI 2 x 80/4.5 μg Bid With Formoterol Turbuhaler®, Budesonide pMDI, the Combination of Formoterol Turbuhaler® and Budesonide pMDI, and Placebo in COPD Patients | April 2005 | December 2006 |
| NCT03741855 | Completed | N/A | Evaluating the Cloud DX Platform as a Tool for Self-management and Asynchronous Remote-monitoring of COPD | January 1, 2018 | March 31, 2019 |
| NCT00006306 | Completed | Effects of Chronic Ozone Exposure on Lung Function | September 1999 | August 2004 | |
| NCT02233686 | Completed | Phase 2 | A Study to Assess the Efficacy of XEN-D0501 in Reducing the Cough Frequency in Patients With COPD | February 2014 | February 2015 |
| NCT02055885 | Completed | Correction of Exercise-induced Desaturation by Acute Oxygen Supply and Exercise Responses in COPD | February 2014 | July 2015 | |
| NCT04531280 | Completed | N/A | Rural Home Hospital: Proof of Concept | February 18, 2021 | May 7, 2021 |
| NCT01125098 | Completed | Comparison of a Serum PRO-CT Guided Treatment and the Recommended Antibiotic Treatment for COPD | October 2006 | December 2011 | |
| NCT01049360 | Completed | Phase 2 | Efficacy and Safety Study of Two Fixed-dose Combinations of Aclidinium Bromide With Formoterol Fumarate Compared With Aclidinium Bromide, Formoterol Fumarate and Placebo | December 2009 | August 2010 |
| NCT00005382 | Completed | Sources of Variability in Peak Expiratory Flow | July 1995 | May 1998 | |
| NCT01692444 | Completed | Role of Fibrocytes in the Bronchial Remodelling of Chronic Obstructive Pulmonary Disease | April 10, 2013 | May 20, 2016 | |
| NCT02818270 | Completed | N/A | Evaluation of Aerosolized Drugs Deposition During Mechanical Ventilation | June 2016 | December 31, 2016 |
| NCT00141440 | Completed | N/A | The Effect of Cycling Off Criteria During Pressure Support Ventilation in Chronic Obstructive Pulmonary Disease (COPD) Patients | July 2005 | March 2007 |
| NCT03492359 | Completed | N/A | Thora-3DI™ for Evaluation of Severity of Chronic Obstructive Pulmonary Disease (COPD) | May 1, 2017 | January 1, 2019 |
| NCT01871025 | Completed | N/A | Early Incentive and Mobilization During COPD Exacerbation | December 2013 | March 2018 |
| NCT01523470 | Completed | Phase 3 | Withdrawal of Non-invasive Ventilation in Chronic Obstructive Pulmonary Disease (COPD) Patients With Acute Hypercapnic Respiratory Failure | November 2010 | October 2011 |
| NCT03749655 | Completed | N/A | Physical Activity Promotion Added to Standard Care Pulmonary Rehabilitation and Cognitive Behavioural Therapy | November 20, 2018 | August 31, 2021 |
| NCT03295474 | Completed | Telemonitoring in Pulmonary Rehabilitation: Feasibility and Acceptability of a Remote Pulse Oxymetry System. | September 28, 2017 | November 30, 2018 | |
| NCT02872090 | Completed | Phase 4 | Effects of Long Acting Bronchodilators on CARDiac Autonomic Control in Chronic Obstructive Pulmonary Disease (COPD) | March 2016 | June 1, 2021 |
| NCT00622635 | Completed | Phase 3 | A Crossover Study to Determine the 24 Hour Lung Function Profile of Indacaterol in Patients With Moderate-to-severe Chronic Obstructive Pulmonary Disease (COPD) | January 2008 | July 2008 |
| NCT03288376 | Completed | SNORE (Smartphone Analyses of Nocturnal Obstruction by Respiratory Evaluation) SOUNDS | February 13, 2015 | January 31, 2017 | |
| NCT01391559 | Completed | N/A | Efficacy of Inhaling Bronchodilator Medications in Chronic Obstructive Pulmonary Disease | July 2011 | October 2012 |
| NCT03704545 | Completed | N/A | Clinical Impact of Pharmaceutical Consultations in Patients Treated for Chronic Obstructive Pulmonary Disease at Home | January 18, 2019 | October 21, 2022 |
| NCT03568747 | Completed | N/A | Efficacy and Mechanism of NIV in Relieving Dyspnea After Exercise in Patients With Stable Severe COPD | June 23, 2018 | April 30, 2019 |
| NCT04614064 | Completed | N/A | London Underground Study - Health Effects of Particulate Matter | August 16, 2021 | July 20, 2023 |
| NCT02123199 | Completed | Study of the Impact of Indacaterol (Onbrez®) on the Individual Lives and Health Status of Patients With COPD | April 2012 | ||
| NCT06256172 | Completed | N/A | Medlink for Diagnosing of Diabetes Mellitus, COPD, CHF, Myasthenia Gravis and Hypertension | June 16, 2023 | December 16, 2023 |
| NCT03094806 | Completed | N/A | Vibratory PEP Device and Hospital Length of Stay for Acute Exacerbation of COPD | October 2013 | December 2015 |
| NCT03188627 | Completed | Phase 1/Phase 2 | Autologous Bronchial Basal Cell Transplantation for Treatment of COPD | June 12, 2018 | December 26, 2019 |
| NCT05448235 | Completed | N/A | the Effectivness of the Thoracic Cage Mobilization on COPD Patients | October 21, 2022 | December 1, 2022 |
| NCT00974805 | Completed | Phase 4 | An Investigation of the Mechanism of Action of Seretide in Chronic Obstructive Pulmonary Disease | February 2010 | February 2012 |
| NCT03321279 | Completed | N/A | Social Incentives to Increase Mobility | January 11, 2018 | September 9, 2019 |
| NCT01069289 | Completed | Phase 3 | Efficacy and Safety Study of Symbicort® Turbuhaler® Versus Oxis® Turbuhaler® in Chronic Obstructive Pulmonary Disease (COPD) Patients | January 2010 | March 2011 |
| NCT00403286 | Completed | Phase 2 | A Dose-Finding Study Evaluating Safety and Efficacy in Patients With Chronic Obstructive Pulmonary Disease | November 2006 | May 2007 |
| NCT03615365 | Completed | COPD Breathing Record Study 2 | August 15, 2017 | November 23, 2018 | |
| NCT01035411 | Completed | Phase 1 | AZD9668 Relative Bioavailability | November 2009 | December 2009 |
| NCT01287325 | Completed | Phase 1/Phase 2 | Efficacy of DNK333 in Patients With COPD and Cough | September 2003 | |
| NCT03177837 | Completed | Phase 4 | Effect of Acetazolamide on Exercise Performance in Patients With Respiratory Disease at Altitude | May 24, 2017 | August 2, 2018 |
| NCT05723302 | Completed | N/A | Chronic Obstructive Pulmonary Diseases and Proprioceptive Neuromuscular Facilitation | January 20, 2017 | December 1, 2022 |
| NCT01110564 | Completed | Study to Investigate Daily Symptom Variability, Symptom Effects on Morning Activities of Chronic Obstructive Disease | April 2010 | December 2010 | |
| NCT01655667 | Completed | Comorbidities and Healthcare Utilisation: Indicators for Improving COPD Diagnosis | December 2010 | June 2012 | |
| NCT01213693 | Completed | N/A | Effects of Inhaled Corticosteroids on Sputum Bacterial Load in COPD | May 2009 | November 2013 |
| NCT02257463 | Completed | N/A | Effect of Inspiratory Muscle Training on Exercise Performance and Quality of Life in Patients With Chronic Obstructive Pulmonary Disease | October 2011 | April 2014 |
| NCT02059005 | Completed | N/A | Specialized Community Disease Management to Reduce Substance Use and Hospital Readmissions | November 18, 2014 | February 28, 2017 |
| NCT00345774 | Completed | Phase 2 | Safety and Effectiveness of PRX-08066 in Patients With Pulmonary Hypertension and Chronic Obstructive Pulmonary Disease | June 2006 | June 2007 |
| NCT03299673 | Completed | AdHerencE to Treatment and quAlity of Life in COPD | December 1, 2017 | December 5, 2018 | |
| NCT01010178 | Completed | Phase 4 | Can Airflow Limitation in Chronic Obstructive Pulmonary Disease (COPD) be Reversible by Drugs? | February 2008 | July 2009 |
| NCT02404831 | Completed | Phase 1/Phase 2 | An Evaluation of Web Based Pulmonary Rehabilitation | April 2014 | May 2015 |
| NCT00465959 | Completed | Phase 1/Phase 2 | Study of Trospium Chloride Inhalation Powder (TrIP) in Patients With Chronic Obstructive Pulmonary Disease | April 2007 | June 2007 |
| NCT01006200 | Completed | Factors to Obstructive Granulation Tissue Formation After Ultraflex Stenting in Benign Tracheal Narrowing | August 2001 | September 2007 | |
| NCT00430729 | Completed | Phase 3 | Effect of Roflumilast on Exacerbation Rate in Patients With Chronic Obstructive Pulmonary Disease. Ratio-Study. (BY217/M2-112) | January 2003 | |
| NCT04248842 | Completed | Wireless Assessment of Respiratory and Circulatory Distress in Chronic Obstructive Pulmonary Disease - Validation Study | January 23, 2020 | June 4, 2020 | |
| NCT00871182 | Completed | Phase 1/Phase 2 | Study to Evaluate the Safety and Efficacy of Inhaled PT001 in Patients With Chronic Obstructive Pulmonary Disease (COPD) | March 2009 | September 2009 |
| NCT00660738 | Completed | Functional Tests in Individuals With Chronic Obstructive Pulmonary Disease (COPD) | January 2007 | February 2008 | |
| NCT04579055 | Completed | N/A | Impact of Chair Seat Height on the 1-Minute Sit to Stand Test Performance in Chronic Obstructive Pulmonary Disease | September 16, 2020 | March 30, 2021 |
| NCT01041586 | Completed | Phase 1 | Bronchoscopic Thermal Vapor Ablation (BTVA) for Lung Volume Reduction | December 2009 | August 2011 |
| NCT00134979 | Completed | Phase 4 | Formoterol Certihaler, Tiotropium HandiHaler and Tiotropium HandiHaler in Combination With Formoterol Certihaler in Patients With Stable Chronic Obstructive Pulmonary Disease | October 2004 | November 2005 |
| NCT00405236 | Completed | Phase 4 | Effect of Tiotropium on Inflammation and Exacerbations in COPD | October 2002 | January 2005 |
| NCT00159549 | Completed | N/A | Long Term Effect of an Education and Training Program for Patients With Chronic Obstructive Pulmonary Disease | January 2000 | December 2005 |
| NCT00006419 | Completed | Diet and Chronic Obstructive Pulmonary Disease | July 2000 | June 2004 | |
| NCT01745848 | Completed | Phase 4 | Roflumilast on Markers of Bone Metabolism and Endothelial Function in COPD | February 2013 | June 30, 2016 |
| NCT02284295 | Completed | Molecular, Cytological Features and Genetic Susceptibility of COPD Attributable to Different Environmental Exposures 2 | November 2014 | November 2014 | |
| NCT02119494 | Completed | Phenotypes of COPD in Central and Eastern Europe | June 2014 | December 2015 | |
| NCT01854177 | Completed | N/A | Differentiating the Effects of Substance P and Beta-endorphin | July 2013 | November 2013 |
| NCT02122627 | Completed | N/A | Vitamin D Supplementation in Patients With COPD | April 10, 2015 | June 26, 2019 |
| NCT03645434 | Completed | Phase 2 | A Single Inhalation Dose Study to Assess Efficacy, Pharmacokinetics (PK), Safety and Tolerability of AZD8871 in Patients With Long-term Lung Diseases. | October 10, 2018 | August 7, 2019 |
| NCT04048954 | Completed | Use of a Smartphone Application on the Detection of Complications Related to Smoking | May 30, 2019 | June 1, 2020 | |
| NCT01543217 | Completed | N/A | Respiratory Disease Management | July 2012 | December 2015 |
| NCT01505543 | Completed | Proprioceptive Postural Control and Chronic Obstructive Pulmonary Disease (COPD) | January 2012 | September 2012 | |
| NCT01118104 | Completed | N/A | Sickness Absence Versus Physical, Mental, and Job-related Factors in Patients With Chronic Pulmonary Disease | January 2008 | December 2011 |
| NCT05110755 | Completed | Correlation of Physical Activity and Respiratory Health in COPD Patient | April 1, 2021 | December 1, 2021 | |
| NCT04326309 | Completed | Audio Data Collection for Identification and Classification of Coughing | March 25, 2020 | January 24, 2022 | |
| NCT01204034 | Completed | Phase 3 | Study to Assess the Effect of Formoterol and Beclomethasone Dipropionate in Patients With Chronic Obstructive Pulmonary Disease (COPD) | September 2010 | June 2012 |
| NCT00087906 | Completed | Disability and Health Outcomes in COPD | July 2004 | May 2009 | |
| NCT03008746 | Completed | N/A | Pulmonary Microbiota in Patients With Chronic Obstructive Pulmonary Disease Colonized With P. Aeruginosa Resistant to Imipenem | January 12, 2017 | May 17, 2022 |
| NCT05035875 | Completed | Evaluation of Diaphragm in Chronic Obstructive Pulmonary Disease Patients by Ultrasound in Relation to Severity | December 14, 2019 | December 14, 2020 | |
| NCT03414541 | Completed | Phase 2 | Safety And Efficacy Study Of Orally Administered DS102 In Patients With Chronic Obstructive Pulmonary Disease | September 24, 2017 | January 29, 2019 |
| NCT00583986 | Completed | Phase 3 | Reliability of a Top Mount Actuation Indicator With Levalbuterol MDI in Adult and Pediatric Subjects With Asthma or COPD | September 2005 | March 2006 |
| NCT03256695 | Completed | Phase 3 | Evaluate the Relationship Between Use of Albuterol Multidose Dry Powder Inhaler With an eModule (eMDPI) and Exacerbations in Participants With Chronic Obstructive Pulmonary Disease (COPD) | September 28, 2017 | April 17, 2018 |
| NCT05528289 | Completed | N/A | Effects on PaCO2 Levels of Two Different Nasal Cannula in COPD Patients | August 4, 2022 | October 30, 2023 |
| NCT05218525 | Completed | N/A | Testing a Prediction Algorithm Into a Running Telehealth System for Patients With COPD | October 1, 2021 | November 30, 2022 |
| NCT00669617 | Completed | Phase 3 | Study to Determine the Onset of Action of Indacaterol in Patients With Moderate to Severe Chronic Obstructive Pulmonary Disease (COPD) | April 2008 | August 2008 |
| NCT03859414 | Completed | Phase 1 | PK of BDP/FF/GB Single-inhaler Triple Therapy in Japanese vs. Caucasians | March 18, 2019 | July 24, 2019 |
| NCT01826682 | Completed | N/A | Physiotherapy in Exacerbation Chronic Obstructive Pulmonary Disease | March 2013 | December 2014 |
| NCT02209974 | Completed | Phase 4 | Effects of Inhaled Corticosteroids in the Systemic Inflammation Induced by Exercise in Patients With COPD | February 2004 | November 2009 |
| NCT04363723 | Completed | The Influence of an Acute Exacerbation During Pulmonary Rehabilitation in COPD Patients Awaiting Lung Transplantation | April 23, 2020 | May 10, 2020 | |
| NCT03173508 | Completed | Phase 4 | Effect of Acetazolamide on Right Ventricular Function at Rest in Patients With Respiratory Disease at Altitude | May 24, 2017 | August 2, 2018 |
| NCT01424137 | Completed | N/A | Inspiratory Flow Parameters of Easyhaler and Diskus Inhalers (SALIF) | September 2011 | November 2011 |
| NCT00883701 | Completed | Granzymes and Perforin at the Onset of Chronic Obstructive Pulmonary Disease (COPD) Exacerbations | December 2002 | September 2009 | |
| NCT00384306 | Completed | Phase 1 | Effects Of Oral Prednisolone On Bone Metabolism In Patients With Chronic Obstructive Pulmonary Disease | June 2004 | January 2006 |
| NCT01298661 | Completed | N/A | Reliability, Sensitivity and Validity of the 6 Minute Step Test in Chronic Obstructive Pulmonary Disease (COPD) Patients | February 2011 | December 2012 |
| NCT00404430 | Completed | Protocol Chronic Obstructive Pulmonary Disease | January 11, 2007 | January 21, 2021 | |
| NCT01068613 | Completed | Phase 2 | Safety and Efficacy of Multiple Doses of QAX028 in Chronic Obstructive Pulmonary Disease (COPD) Patients | January 2010 | August 2010 |
| NCT06432920 | Completed | N/A | A Wearable In-phase Chest Wall Vibration Device for Relief of Dyspnoea in COPD: a First-in-human Exploratory Study | July 6, 2023 | January 26, 2024 |
| NCT05251623 | Completed | N/A | Walking Program With Pedometer on Quality of Life in COPD | March 1, 2018 | March 31, 2019 |
| NCT00394225 | Completed | N/A | Helium-Hyperoxia and 6MWT Distance in COPD | July 2005 | May 2006 |
| NCT01151306 | Completed | Phase 4 | The Effect of Statins in Patients With Chronic Obstructive Pulmonary Disease (COPD) | June 2010 | August 2013 |
| NCT02552472 | Completed | A Study of Inhaler Use in the Community | August 2012 | October 2015 | |
| NCT00037739 | Completed | Chronic Obstructive Pulmonary Disease Gene Localization | April 2001 | March 2004 | |
| NCT03750292 | Completed | N/A | Residential Cleaning of Indoor Air to Protect COPD Patients | March 18, 2019 | March 26, 2021 |
| NCT04952883 | Completed | Hydrogen Sulfide and Pulmonary Vascular Remodeling on HRCT in Patients With COPD | December 1, 2016 | December 1, 2017 | |
| NCT04895124 | Completed | Second Follow-up Study of COPD Patients and Healthy Controls for Evaluation of Predictive Non-coding RNA Biomarkers | May 25, 2021 | March 30, 2023 | |
| NCT02366390 | Completed | Phase 4 | Dialogue Aimed at Reducing Anxiety in Patients With Severe COPD | February 2015 | April 2016 |
| NCT01108835 | Completed | N/A | A Comprehensive Care Programme for Patients With Chronic Obstructive Pulmonary Disease | April 2010 | July 2015 |
| NCT04535986 | Completed | Phase 3 | A Phase 3 Clinical Trial to Evaluate the Safety and Efficacy of Ensifentrine in Patients With COPD | September 29, 2020 | December 2, 2022 |
| NCT01529489 | Completed | N/A | Effect of Two Physical Training Programs on Oxygen Uptake and Heart Rate On-kinetics in Patients COPD | January 2008 | December 2011 |
| NCT01437540 | Completed | Phase 3 | Safety and Tolerability of Aclidinium Bromide/Formoterol Fumarate Compared With Formoterol Fumarate in Patients With Moderate to Severe Chronic Obstructive Pulmonary Disease | September 19, 2011 | April 30, 2013 |
| NCT02157844 | Completed | Fat Metabolism in OSA and COPD | April 2014 | December 2017 | |
| NCT01033266 | Completed | Effect of Nasal CPAP on Cardiopulmonary Exercise Testing in Patients With Overlap Syndrome | February 1, 2009 | February 28, 2014 | |
| NCT02487498 | Completed | Phase 3 | Efficacy and Safety Study of Indacaterol Maleate/Glycopyrronium Bromide in Chronic Obstructive Pulmonary Disease (COPD) Patients. | July 27, 2015 | September 6, 2016 |
| NCT03378648 | Completed | Phase 1/Phase 2 | A Study to Investigate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Single Dose in Healthy Volunteers, Repeat Doses in Asthmatic Patients and of Single Dose in COPD Patients of CHF6366 | December 28, 2017 | April 16, 2019 |
| NCT02140346 | Completed | Phase 1 | A Study to Investigate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Repeat Doses of RV1729 for 28 Days in Patients With COPD | August 2014 | July 2015 |
| NCT00005281 | Completed | Early Risk Predictors For Chronic Pulmonary Disease | September 1977 | November 1998 | |
| NCT00917150 | Completed | Phase 2 | To Investigate the Efficacy and Safety of OPC-6535 in Chronic Obstructive Pulmonary Disease (COPD) Patients | March 2009 | April 2014 |
| NCT01426893 | Completed | Observational Study to Evaluate the Correctness of the Use of Inhaler Device in Patients With Asthma or Chronic Obstruct | October 2011 | March 2012 | |
| NCT02181023 | Completed | Phase 4 | Acute Effect of Aclidinium on Hyperinflation and Ventilation Inhomogeneity in Severe COPD Patients | June 2014 | October 2014 |
| NCT00005280 | Completed | Specialized Center of Research in Occupational and Immunologic Lung Disease | June 1972 | November 1991 | |
| NCT00000573 | Completed | Phase 2 | Emphysema: Physiologic Effects of Nutritional Support | January 1990 | November 2005 |
| NCT00640484 | Completed | Phase 2 | Confirmatory Dose Finding Study of 2 Dosages of CHF 4226 pMDI (Carmoterol) in Patients With COPD | April 2008 | October 2008 |
| NCT00774761 | Completed | Phase 2 | A Study Evaluating Systemic Exposure and Pharmacodynamics in Patients With Chronic Obstructive Pulmonary Disease | November 2008 | May 2009 |
| NCT00491803 | Completed | Phase 4 | Sildenafil Effects on Pulmonary Haemodynamics and Gas Exchange in Chronic Obstructive Pulmonary Disease (COPD) | June 2007 | February 2009 |
| NCT02418468 | Completed | Phase 4 | Effects of Indacaterol in Symptomatic COPD Patients With Low Risk of Exacerbations | April 28, 2015 | April 19, 2016 |
| NCT00511290 | Completed | Measurement of Soluble Factors and Particulate Matter in Induced Sputum and EBC in Inflammatory Diseases of the Lung | |||
| NCT01418469 | Completed | N/A | Disturbances in BCAA Metabolism and the Effects of Feeding and Exercise in COPD | December 2002 | December 2004 |
| NCT00532350 | Completed | Phase 1 | Safety and Tolerability QAT370 Compared to Tiotropium in Patients With Chronic Obstructive Pulmonary Disease | July 2007 | January 2008 |
| NCT01380405 | Completed | N/A | Educational Intervention for Managing Inhalers in Chronic Obstructive Pulmonary Disease (COPD) Patients | May 2011 | December 2011 |
| NCT04415957 | Completed | N/A | Elastic Tape Relieves Symptoms and Improves Health-related Quality of Life in COPD (Chronic Obstructive Pulmonary Disease) | February 1, 2019 | May 1, 2022 |
| NCT05523180 | Completed | N/A | A Study to Evaluate the Effect of Probiotic Supplement on Quality of Life | September 1, 2022 | September 12, 2023 |
| NCT03425617 | Completed | Phase 4 | Effects of Dual Bronchodilator Treatment on Cardiopulmonary Interactions in COPD | January 1, 2017 | June 30, 2018 |
| NCT00639236 | Completed | Phase 4 | Effectiveness and Safety of Inhaling Hypertonic Saline in Patients With Chronic Obstructive Pulmonary Disease | May 2004 | November 2006 |
| NCT01349608 | Completed | N/A | Physical Activity Coaching in Chronic Obstructive Pulmonary Disease (COPD) | April 2011 | March 2013 |
| NCT01348555 | Completed | Phase 1/Phase 2 | Safety, Preliminary Pharmacokinetics and Bronchodilator Properties of V0162 | April 2011 | July 2012 |
| NCT04485832 | Completed | N/A | Telehealth Could Mitigate Disease Progression Compared to Standard of Care in COPD - a Randomized Controlled Trial | April 5, 2016 | December 1, 2019 |
| NCT00889837 | Completed | Phase 1 | Staccato Loxapine Pulmonary Safety in Patients With COPD | June 2009 | August 2009 |
| NCT04540562 | Completed | N/A | Evaluating a Mobile Self-management Application for Patients With COPD Chronic Obstructive Pulmonary Disease | November 22, 2018 | April 25, 2020 |
| NCT01380626 | Completed | N/A | Effects of Exercise Training in Chronic Obstructive Pulmonary Disease Versus Alpha-1-Antitrypsin-deficiency-patients | February 2010 | April 2013 |
| NCT05518981 | Completed | Effect of Remote Physiologic Monitoring (RPM) on Outcomes in COPD Patients | May 1, 2019 | February 28, 2022 | |
| NCT03627858 | Completed | Fixed Dose Triple Therapy in Severe Chronic Obstructive Pulmonary Disease in a Real World Setting | August 1, 2018 | August 3, 2020 | |
| NCT00826683 | Completed | Phase 3 | Detection of Circulating Endothelial Progenitors Cells (EPCs) in Non-small Cell Lung Cancer (NSCLC) | March 2009 | January 2011 |
| NCT00005425 | Completed | Statistical Analysis of Vlagtwedde-Vlaardingen Data Set | September 1992 | February 1995 | |
| NCT01555138 | Completed | Phase 4 | Comparison of Indacaterol 150 mcg Once Daily (o.d.) With Salmeterol/Fluticasone Propionate 50 mcg/500 mcg Twice Daily (b.i.d.) | February 2012 | February 2014 |
| NCT03406936 | Completed | N/A | Sedation and Ease of Weaning From Mechanical Ventilation | August 20, 2016 | October 30, 2017 |
| NCT01931644 | Completed | At-Home Research Study for Patients With Autoimmune, Inflammatory, Genetic, Hematological, Infectious, Neurological, CNS, Oncological, Respiratory, Metabolic Conditions | July 2013 | April 2024 | |
| NCT00170222 | Completed | Phase 4 | Placebo Versus Antibiotics in Acute Exacerbations of Chronic Obstructive Pulmonary Disease (COPD) | July 2002 | August 2008 |
| NCT02892396 | Completed | Influence of Electronic Cigarettes in the Evaluation of the Inflammatory Response in Patients With a Diagnosis of COPD | October 1, 2016 | March 2019 | |
| NCT05497999 | Completed | N/A | Racial Inequality in Inhaler Fills for COPD - A Trial of Reduced Cost-Sharing | January 7, 2020 | December 31, 2022 |
| NCT06297668 | Completed | Phase 1 | A Study to Assess the Pharmacokinetics and Safety of Budesonide, Glycopyrronium, & Formoterol (BGF) Metered Dose Inhaler (MDI) Hydrofluoroolefin (HFO) With a Spacer (Treatment B), BGF MDI Hydrofluoroalkane (HFA) With a Spacer (Treatment A), as Well as BGF MDI HFO Without a Spacer (Treatment C). | April 29, 2024 | June 11, 2024 |
| NCT03015090 | Completed | N/A | Association Study Between CYP1A2 Gene Polymorphisms and Metabolism of Theophylline | January 1, 2017 | June 1, 2017 |
| NCT03821311 | Completed | N/A | Investigating the Effect of Nasal High Flow Oxygen Therapy on Regional Lung Function | December 6, 2018 | June 18, 2019 |
| NCT01572792 | Completed | Phase 3 | Efficacy, Safety and Tolerability of Two Fixed Dose Combinations of Aclidinium Bromide/Formoterol Fumarate, Aclidinium Bromide, Formoterol Fumarate and Placebo for 28-Weeks Treatment in Patients With Moderate to Severe, Stable Chronic Obstructive Pulmonary Disease (COPD) | April 2012 | June 2013 |
| NCT02424331 | Completed | N/A | Effect of Pursed Lips Breathing on Chest Wall, Mobility Diaphragmatic and Exercise Tolerance in Patients With Chronic Obstructive Pulmonary Disease | March 2014 | March 2015 |
| NCT00581945 | Completed | Phase 1/Phase 2 | Safety and Efficacy of Multiple Doses of Canakinumab (ACZ885) in Chronic Obstructive Pulmonary Disease (COPD) Patients | January 2007 | May 2010 |
| NCT01577329 | Completed | N/A | Mindfulness Mediation Intervention in Chronic Obstructive Pulmonary Disease (COPD) | October 2011 | July 2015 |
| NCT00856193 | Completed | Phase 2 | A Study to Investigate the Bronchodilatory Effect of NVA237 in Patients With Chronic Obstructive Pulmonary Disease (COPD) | February 2009 | May 2009 |
| NCT02282202 | Completed | N/A | Evaluation of Oscillatory Positive Expiratory Pressure (oPEP) in Bronchiectasis and COPD | September 2013 | September 2014 |
| NCT02895152 | Completed | N/A | Activity Monitor Use in COPD Patients Undergoing Rehabilitation | August 2016 | June 2018 |
| NCT02665130 | Completed | Phase 4 | Comparison of Tai Chi and Pulmonary Rehabilitation on the Effect of Indacaterol in Treatment naïve COPD Participants | December 2014 | August 2016 |
| NCT01867970 | Completed | N/A | Interactive Tool to Support Self-management Through Lifestyle Feedback, Aimed at Physical Activity of COPD/DM Patients | April 2013 | October 2014 |
| NCT00419744 | Completed | Phase 3 | A Comparison of SYMBICORT® pMDI With Formoterol Turbuhaler® in Subjects With COPD | January 2007 | August 2009 |
| NCT01933984 | Completed | N/A | Individualized Dosing Schedule of Inhaled Bronchodilator for Endotracheally Intubated COPD Patients | August 2013 | January 31, 2019 |
| NCT02598830 | Completed | N/A | The Granheim COPD Study - Vitamin D and Strength Training | November 2015 | June 2018 |
| NCT03286855 | Completed | N/A | Effectiveness of Vibrating Mesh Versus Small Volume Nebuliser in Chronic Obstructive Pulmonary Disease (COPD) | October 18, 2017 | September 30, 2018 |
| NCT01319656 | Completed | N/A | Integration of Chronic Disease Rehabilitation Services Into Primary Care | February 2011 | November 2013 |
| NCT00992680 | Completed | Phase 2 | A Pilot Study to Evaluate the ROX Anastomotic Coupler System in Patients With Chronic Obstructive Pulmonary Disease | September 2009 | December 2013 |
| NCT00476099 | Completed | Phase 3 | Efficacy and Safety Study of Beclometasone/Formoterol Single Inhaler in Patients With COPD | December 2006 | November 2008 |
| NCT02055352 | Completed | Phase 4 | Study to Evaluate Efficacy/Safety of Combination Budesonide/Indacaterol vs Fluticasone/Salmeterol in Patients With COPD | May 30, 2014 | January 26, 2016 |
| NCT01056081 | Completed | Phase 3 | Inspiratory Muscle Training in Chronic Obstructive Pulmonary Disease | April 2006 | December 2008 |
| NCT04352829 | Completed | N/A | VIDEO-TRAINING-SESSION ON METERED DOSE INHALER SKILLS AMONG INDIVIDUALS WITH COPD | February 1, 2017 | July 1, 2017 |
| NCT03381560 | Completed | A Study to Evaluate the Symptoms Over 24 Hours in Patients With Chronic Obstructive Pulmonary Disease - LASSYC Study | November 7, 2017 | June 30, 2018 | |
| NCT03885128 | Completed | N/A | Intra Versus Extra-thoracic Oscillations in Chronic Obstructive Pulmonary Disease | November 1, 2017 | May 30, 2019 |
| NCT01709903 | Completed | Phase 3 | A 26-week Treatment Randomized, Double-blind, Double Dummy Study to Assess the Efficacy and Safety of QVA149 | November 2012 | February 2014 |
| NCT04876677 | Completed | Phase 3 | Functional Respiratory Imaging Study | May 25, 2021 | January 3, 2022 |
| NCT01708278 | Completed | Phase 1 | Beneficial Effects of Quercetin in Chronic Obstructive Pulmonary Disease (COPD) | February 2014 | October 2015 |
| NCT02614105 | Completed | N/A | Urinary Incontinence Amongst Women With Chronic Obstructive Pulmonary Disease | November 2015 | December 2018 |
| NCT04107493 | Completed | N/A | Evaluation of a Portable Oxygen Concentrator During Ambulation for Patients Who Require Supplemental Oxygen (POC-LEAN) | November 21, 2019 | March 9, 2020 |
| NCT02203058 | Completed | N/A | Pursed-lips Breathing and Dynamic Hyperinflation | March 2012 | July 2013 |
| NCT01656005 | Completed | Phase 4 | Beta Blocker Therapy in Moderate to Severe COPD | August 2012 | July 2016 |
| NCT03120169 | Completed | N/A | Effects of Treadmill Versus Cycling Endurance Training in Patients With COPD | March 30, 2017 | November 27, 2017 |
| NCT01825538 | Completed | Assessment of Pulmonary Specialty Physicians' Approach to Advanced Care Planning in Patients With Chronic Pulmonary Diseases | February 2013 | June 2014 | |
| NCT00836108 | Completed | N/A | Unsupported Arm Exercise and Breathing Strategy in Patients With Chronic Obstructive Pulmonary Disease | February 2009 | May 2012 |
| NCT04655534 | Completed | N/A | The Effect of Inspiratory Muscle Warm-Up in Patients With COPD | June 1, 2019 | December 28, 2020 |
| NCT00744484 | Completed | N/A | A 12 Week Physical Training Programme for Patients With Chronic Obstructive Pulmonary Disease | February 2008 | September 2010 |
| NCT00870246 | Completed | Diaphragmatic Mobility and Chronic Obstructive Pulmonary Disease | February 2008 | November 2008 | |
| NCT01247870 | Completed | Phase 4 | Metformin in Chronic Obstructive Pulmonary Disease | January 2011 | May 2014 |
| NCT01424098 | Completed | N/A | Balance Training in Patients With Chronic Obstructive Pulmonary Disease (COPD) | August 2011 | September 2012 |
| NCT01091623 | Completed | N/A | Effects of Strength Training in Combination With Endurance Training on Exercise Tolerance in Patients With Chronic Obstructive Pulmonary Disease (COPD) | June 2005 | |
| NCT05922293 | Completed | N/A | Combined Effects of Blow Bottle Technique and Percussion Technique in COPD Patients | June 15, 2023 | December 5, 2023 |
| NCT01007734 | Completed | Factors Determining Quality of Life Related to Respiratory Status According to Gender of Chronic Obstructive Pulmonary Disease (COPD) Patients | October 2009 | July 2010 | |
| NCT03268226 | Completed | Phase 3 | Functional Respiratory Imaging Study (FRI) | November 20, 2017 | January 30, 2019 |
| NCT02324660 | Completed | N/A | Screening for Chronic Obstructive Pulmonary Disease in Patients With Acute Coronary Syndromes | December 2014 | October 2016 |
| NCT00974142 | Completed | Phase 1/Phase 2 | Oral Cyclosporine in Chronic Obstructive Pulmonary Disease | September 2009 | December 2016 |
| NCT04955405 | Completed | N/A | The 7-Visit Transition of Care Hospital to Home Intervention: A Pilot Study | January 31, 2022 | October 31, 2023 |
| NCT00479284 | Completed | N/A | Efficacy of Average Volume Assured Pressure Support With Bi-Level Pressure Support Nocturnal Ventilation | June 2006 | May 2007 |
| NCT01945398 | Completed | N/A | IMT in Ventilatory Muscle Metaboreflex in COPD | June 2013 | February 2015 |
| NCT02067780 | Completed | Phase 3 | Short Antibiotic Treatment Versus Duration Guided by Markers of Inflammation in the Treatment of AECOPD | May 1, 2017 | January 31, 2019 |
| NCT03467815 | Completed | Wireless Assessment of Respiratory and Circulatory Distress in Chronic Obstructive Pulmonary Disease | March 15, 2018 | June 7, 2018 | |
| NCT05097014 | Completed | Phase 4 | CHF5993 and CHF1535 pMDI on Lung Hyperinflation and Exercise Endurance Time in Subjects With COPD | October 28, 2021 | February 24, 2023 |
| NCT00561223 | Completed | N/A | Iloprost in Gas Exchange/Pulm Mechanics in Chronic Obstructive Pulmonary Disease (COPD) | November 2006 | October 31, 2012 |
| NCT01753427 | Completed | Perception of Symptom Variability in COPD | December 2012 | November 2013 | |
| NCT01245569 | Completed | Phase 3 | A Study in Patients With Chronic Obstructive Pulmonary Disease | April 2011 | March 2012 |
| NCT01350128 | Completed | Phase 2 | PT001 MDI Versus Atrovent Study in Moderate to Severe Chronic Obstructive Pulmonary Disease (COPD) | May 1, 2011 | October 1, 2011 |
| NCT03089853 | Completed | N/A | Smart Telehealth Exercise Intervention to Reduce COPD Readmissions | July 14, 2016 | August 15, 2020 |
| NCT01042080 | Completed | N/A | Neurally Adjusted Ventilatory Assist and Synchrony in Patients With Chronic Obstructive Pulmonary Disease (COPD) | December 2009 | September 2019 |
| NCT01645358 | Completed | Phase 4 | Helmet Ventilation in Acute Hypercapnic Respiratory Failure | July 2012 | September 2014 |
| NCT02156245 | Completed | N/A | Evaluation of the Effects of Eccentric Training on a Cycle Ergometer, Versus Conventional Concentric Training | September 16, 2013 | April 3, 2019 |
| NCT00992498 | Completed | Rehabilitation in Chronic Obstructive Pulmonary Disease Outpatients | January 2008 | December 2009 | |
| NCT01520376 | Completed | N/A | Anxiety and Depression in Patients Hospitalizes for an Acute Exacerbation of COPD | October 2011 | April 2014 |
| NCT01639274 | Completed | N/A | Human Immunodeficiency Virus (HIV)and Chronic Obstructive Pulmonary Disease (COPD) | January 2012 | November 2013 |
| NCT00578968 | Completed | Phase 4 | Cardiac Limitations in Chronic Obstructive Pulmonary Disease: Benefits of Bronchodilation | October 2006 | August 2008 |
| NCT00000564 | Completed | Phase 3 | Nocturnal Oxygen Therapy | July 1976 | |
| NCT02386761 | Completed | Phase 1 | A Study to Investigate the Safety, Tolerability and Pharmacokinetics of Inhaled CHF6001 | November 2014 | May 2015 |
| NCT00013156 | Completed | Phase 2 | Cost-Effectiveness of Lung Volume Reduction Surgery | March 2000 | |
| NCT03287440 | Completed | N/A | Rehabilitation for Patients With COPD | September 1, 2017 | July 30, 2020 |
| NCT01047553 | Completed | Phase 3 | Study to Evaluate the Safety and Efficacy of Formoterol in a Daily Dose of 18 µg (9 µg Twice Daily) in Japanese Chronic Obstructive Pulmonary Disease (COPD) Patients | December 2009 | July 2011 |
| NCT02542254 | Completed | Phase 2 | The Effects of RPL554 on Top of Standard COPD Reliever Medications | October 2015 | December 2015 |
| NCT00758459 | Completed | Phase 2 | Safety/Tolerability Study With AZD1236 in Chronic Obstructive Pulmonary Disease (COPD) Patients | September 2008 | March 2009 |
| NCT02135744 | Completed | N/A | Pre-Discharge Bundle for Patients With Acute Exacerbations of Chronic Obstructive Pulmonary Disease to Reduce Readmissions | February 2010 | April 2013 |
| NCT04999930 | Completed | N/A | Tiotropium Respimat Administration With and Without Aerochamber Disease (COPD) | January 10, 2020 | February 28, 2021 |
| NCT02744170 | Completed | N/A | Effects of Supplemental Oxygen Delivery Via Demand Versus Continuous Flow in Hypoxemic COPD Patients | April 2016 | October 2018 |
| NCT02546700 | Completed | Phase 2 | A Study to Evaluate Safety and Efficacy of Lebrikizumab in Participants With Chronic Obstructive Pulmonary Disease (COPD) | September 30, 2015 | November 25, 2016 |
| NCT00005279 | Completed | Tucson Epidemiology Study of Chronic Obstructive Lung Diseases | June 1971 | November 1997 | |
| NCT01020344 | Completed | N/A | Mechanisms of Vascular Damage in Patients With Chronic Obstructive Pulmonary Disease | November 2009 | October 2014 |
| NCT02955108 | Completed | N/A | The Effect of Distractive Auditory Stimuli (Music) on Dyspnea and Anxiety During Exercise in Adults With Chronic Respiratory Diseases | October 27, 2017 | November 14, 2018 |
| NCT02796677 | Completed | Phase 3 | AMPLIFY - D6571C00001 Duaklir USA Phase III Study | July 5, 2016 | June 8, 2017 |
| NCT02968914 | Completed | Phase 1 | Pharmacokinetic Comparability of Benralizumab Using Accessorized Pre-Filled Syringe or Autoinjector in Healthy Volunteers | January 4, 2017 | July 13, 2017 |
| NCT01759199 | Completed | N/A | The Six-minute Stepper Test as an Outcome Measure of Exercise Tolerance During Pulmonary Rehabilitation in With Chronic Obstructive Pulmonary Disease (COPD) Patients(STEPPER)? | September 2012 | August 2013 |
| NCT00903955 | Completed | Mucus Dehydration and Evolution of Chronic Obstructive Pulmonary Disease (COPD) Lung Disease | September 2006 | March 2012 | |
| NCT00424268 | Completed | Phase 3 | Effect of Roflumilast in Chronic Obstructive Pulmonary Disease (COPD) Patients Treated With Tiotropium: The HELIOS Study (BY217/M2-128) | January 2007 | July 2008 |
| NCT00421122 | Completed | Phase 3 | Efficacy and Safety Study of Symbicort Turbuhaler in Chinese Patients With COPD | September 2006 | November 2007 |
| NCT05885152 | Completed | N/A | Acute Effect of Whole-body Electrical Stimulation in COPD Patients | July 1, 2023 | September 1, 2023 |
| NCT02080442 | Completed | Balance Training for Chronic Obstructive Pulmonary Disease (COPD) | May 2013 | February 2014 | |
| NCT04279730 | Completed | Fatigue and Physical Performance During Pulmonary Rehabilitation | February 15, 2020 | April 9, 2021 | |
| NCT00672802 | Completed | Phase 2 | Safety of Ramelteon in Subjects With Mild to Moderate Chronic Obstructive Pulmonary Disease | August 2003 | March 2004 |
| NCT00005288 | Completed | Epidemiology and Pulmonary Response To Organic Dust Exposure | December 1986 | November 1991 | |
| NCT03037255 | Completed | Association of Long-term Conditions With Survival Following Heart Attack in England and Wales | January 2003 | January 2021 | |
| NCT01061970 | Completed | Phase 2 | Efficacy and Safety of Fispemifene in the Treatment of Hypogonadal Men With Chronic Obstructive Pulmonary Disease That Are on Oral Glucocorticoid Therapy | January 2007 | October 2007 |
| NCT02660437 | Completed | N/A | pCO2 Oscillations During Exercise: Relation to Cerebral Blood Flow and to Cognitive Dysfunction in COPD | March 2016 | July 2018 |
| NCT00620022 | Completed | Phase 3 | The Effect of Indacaterol on Exercise Endurance in Patients With Moderate to Severe Chronic Obstructive Pulmonary Disease | April 2008 | January 2009 |
| NCT01153321 | Completed | Phase 2 | Investigation of the Effect of Oral Treatment With 100 mg AZD2423 in Subjects With Mild Chronic Obstructive Pulmonary Disease (COPD) | October 2010 | July 2011 |
| NCT03554460 | Completed | N/A | Evaluation of CO2 Rebreathing During Exercise With the Increasing Ventilation Assisted by NIV With a Dual-limb Circuit | June 23, 2018 | March 31, 2019 |
| NCT04840628 | Completed | N/A | The Relationship Between the Neural Drive and Intrinsic Positive End-expiratory Pressure | November 20, 2020 | July 3, 2021 |
| NCT05165485 | Completed | Phase 4 | Phase 4 COPD and Suboptimal Inspiratory Flow Rate | January 7, 2022 | November 20, 2023 |
| NCT00846287 | Completed | N/A | Assessment of Arformoterol for Chronic Obstructive Pulmonary Disease (COPD) Using Hyperpolarized 3He MRI | November 2008 | April 2011 |
| NCT04929990 | Completed | N/A | The Effect of Respiratory Muscle Training for Patients With COPD and Mild Cognitive Impairment | August 7, 2018 | June 2, 2021 |
| NCT01215825 | Completed | The Doses of Systemic Steroid in Acute Exacerbation of Chronic Obstructive Pulmonary Disease (AECOPD) | January 2010 | July 2010 | |
| NCT01012765 | Completed | Phase 3 | Effect of Indacaterol on Inspiratory Capacity (IC) | November 2009 | |
| NCT01216592 | Completed | Airway Inflammation, Symptoms and Lung Function in COPD | January 2009 | July 2011 | |
| NCT00122135 | Completed | N/A | A Culturally Sensitive Values-Guided Aid for End of Life Decision-Making | December 2004 | September 2009 |
| NCT01865435 | Completed | N/A | IN UTERO SMOKING AND PREMATURE CELLULAR SENESCENCE | March 2014 | April 2015 |
| NCT00525564 | Completed | Phase 4 | Effects of Salmeterol on Walking Capacity in Patients With COPD | May 2006 | October 2006 |
| NCT01798420 | Completed | Corticosteroids and Hemoglobin A1C Levels in Diabetic Patients With COPD Exacerbation | April 2012 | October 2012 | |
| NCT03109483 | Completed | N/A | Effectiveness of the Geriatric Activation Program Pellenberg (GAPP) on the Geriatric Rehabilitation Ward | March 17, 2017 | March 30, 2019 |
| NCT02504814 | Completed | N/A | Physiological and Clinical Changes in NHF Therapy | June 2011 | June 2018 |
| NCT02661321 | Completed | Location and Timing of Inhaler Use, Exacerbations and Physical Activity in Chronic Obstructive Pulmonary Disease | December 2011 | January 2014 | |
| NCT01527773 | Completed | Phenotypes and Vascular Damage in Chronic Obstructive Pulmonary Disease (COPD) | May 2011 | January 2017 | |
| NCT05337163 | Completed | A Multicenter Clinical Trial of Sputum DNA Testing for Lung Cancer in China | February 25, 2022 | August 29, 2023 | |
| NCT01337726 | Completed | N/A | Combined Illness Management and Psychotherapy in Treating Depressed Elders | February 2011 | October 2016 |
| NCT03506906 | Completed | N/A | The Debated Role of Sleep Studies in Patients Under Established Home Mechanical Ventilation | November 11, 2018 | September 21, 2020 |
| NCT01371149 | Completed | Phase 2 | Patient -Ventilator Interaction in Chronic Respiratory Failure | January 2011 | April 2014 |
| NCT00697177 | Completed | The Prevalence of Gastro-oesophageal Reflux in Chronic Lung Disease | July 2005 | June 2009 | |
| NCT02216630 | Completed | Phase 1/Phase 2 | Safety and Efficacy of Adipose Derived Stem Cells for Chronic Obstructive Pulmonary Disease | August 2014 | July 2017 |
| NCT02698007 | Completed | N/A | Safety and Benefits of Using Laryngeal Mask Airway to Keep Airway Potency During Fiber-optic Bronchoscopy | April 2016 | October 2016 |
| NCT01944072 | Completed | N/A | Pulmonary Rehabilitation in COPD: Effects of Two Aerobic Exercise Intensity in Patient-centered Outcomes | September 2009 | March 2010 |
| NCT02235025 | Completed | N/A | Asymptomatic Versus Symptomatic Mild COPD: Comparisons at Rest and at Exercise | September 2012 | May 2014 |
| NCT03127852 | Completed | N/A | Effects of Remote Patient Monitoring on Chronic Disease Management | August 23, 2016 | December 15, 2020 |
| NCT01715493 | Completed | Phase 4 | Pharmacological Effect of Lysozyme for Chronic Obstructive Pulmonary Disease and Asthma With Sputum Symptom | October 2012 | January 2014 |
| NCT01561625 | Completed | N/A | Signaling Pathway Activation After Exercise in Patients With Chronic Obstructive Pulmonary Disease | October 2009 | April 2013 |
| NCT04008862 | Completed | N/A | Partnership-based Nursing Practice for Lung Patients and Their Families | May 28, 2018 | December 30, 2020 |
| NCT00870896 | Completed | Early Phase 1 | The Effects of Tiotropium on the Cough Reflex in Patients With Chronic Obstructive Pulmonary Disease (COPD) | February 2008 | June 2012 |
| NCT03244059 | Completed | Phase 2 | Belimumab Treatment of Emphysema Patients With Anti-GRP78 Autoantibodies | August 9, 2018 | April 1, 2022 |
| NCT04117412 | Completed | N/A | The Oxidative Stress, Inflammatory Markers, and Metabolomics Response to Exercise in Patients With COPD | March 15, 2019 | March 15, 2021 |
| NCT03312322 | Completed | N/A | Effects of Lumbar Transcutaneous Electrical Nerve Stimulation on Exercise Performance in Patients With Chronic Obstructive Pulmonary Disease | December 12, 2017 | October 26, 2018 |
| NCT05771506 | Completed | Determinants of Balance in Patients With Chronic Obstructive Pulmonary Disease | January 1, 2023 | May 31, 2023 | |
| NCT02100332 | Completed | A Cross Sectional Disease/Condition Focused Observational Study on Chronic Obstructive Pulmonary Disease (COPD) | November 2012 | July 2014 | |
| NCT05922267 | Completed | N/A | Comparative Effects of ACBT and Slow Expiration in Patients With Chronic Obstructive Pulmonary Disease | June 15, 2023 | December 5, 2023 |
| NCT00232674 | Completed | Phase 4 | Efficacy Study of the Effect of Budesonide on Emphysema | July 1999 | February 2004 |
| NCT03263754 | Completed | N/A | Do Educational Digital Films Enhance Patient COPD Outcomes? | September 1, 2016 | July 2018 |
| NCT00000569 | Completed | Phase 3 | Lung Health Study II | September 1993 | May 1999 |
| NCT01349868 | Completed | Phase 2 | PT005 MDI Dose Ranging Versus Foradil Aerolizer Study | May 2011 | July 2011 |
| NCT01005901 | Completed | Phase 3 | A Study to Assess the Safety, Tolerability and Efficacy of NVA237 Versus Placebo | October 2009 | December 2010 |
| NCT00129584 | Completed | Phase 3 | Endobronchial Valve for Emphysema Palliation Trial (VENT) | January 2004 | |
| NCT03950531 | Completed | The Effect of Bronchiectasis on the Exacerbation and Mortality in COPD | January 25, 2010 | January 25, 2017 | |
| NCT02233543 | Completed | Phase 4 | A Multicenter, 4-week Crossover (Total Duration 12 Weeks) to Determine the Impact of QVA149 on Nocturnal Oxygen Levels in Chronic Obstructive Pulmonary Disease (COPD) | November 30, 2014 | June 26, 2016 |
| NCT03075267 | Completed | Phase 1 | Pharmacokinetics and Safety Study of PT010 and PT003 in Healthy Chinese Adult Subjects | April 17, 2017 | September 5, 2017 |
| NCT05781867 | Completed | N/A | Selective Manual Therapy Techniques in Chronic Obstructive Pulmonary Disease | March 20, 2023 | March 1, 2024 |
| NCT01973647 | Completed | N/A | A Behavioral Therapy for Insomnia Co-existing With COPD | June 2014 | July 2019 |
| NCT00648245 | Completed | Phase 2 | Effectiveness and Safety of BIO-11006 Inhalation Solution to Treat the Overproduction of Mucus and Inflammation in COPD | June 2008 | July 2010 |
| NCT00864812 | Completed | Phase 4 | Clinical Outcomes of Tiotropium Plus Fluticasone Propionate/Salmeterol Compared With Tiotropium for Chronic Obstructive Pulmonary Disease (COPD) in Korea | March 2009 | March 2010 |
| NCT00458419 | Completed | N/A | Role of Endorphins in the Perception of Dyspnea in Patients With Chronic Obstructive Pulmonary Disease | September 2005 | May 2007 |
| NCT03755544 | Completed | Salmeterol/Fluticasone Easyhaler in the Treatment of Asthma and COPD | January 16, 2019 | February 13, 2020 | |
| NCT02114515 | Completed | N/A | PATient Navigator to rEduce Readmissions | July 2014 | October 2016 |
| NCT04791267 | Completed | N/A | ENCOMPASS: Expansion Study C | August 17, 2021 | January 28, 2024 |
| NCT01120691 | Completed | Phase 3 | Effect of QVA149 Versus NVA237 and Tiotropium on Chronic Obstructive Pulmonary Disorder (COPD) Exacerbations | April 2010 | July 2012 |
| NCT02980575 | Completed | N/A | Music During Pulmonary Rehabilitation for Patients With COPD | November 2016 | June 30, 2023 |
| NCT03388489 | Completed | N/A | Mind-Body Walking Exercise for Chronic Obstructive Pulmonary Disease | August 18, 2014 | August 13, 2015 |
| NCT00406705 | Completed | Phase 2 | The Effect of Breathing Helium-Hyperoxia During Pulmonary Rehabilitation in Patients With COPD | March 2005 | January 2007 |
| NCT00540163 | Completed | Observational Non-interventional Study With Spiriva in Chronic Obstructive Pulmonary Disease Patients With Exercise-induced Dyspnoea | April 2007 | ||
| NCT01979081 | Completed | Detecting and Addressing Preclinical Disability | January 2013 | December 2017 | |
| NCT06077357 | Completed | N/A | Evaluation in Individuals With COPD and Asymptomatic Individuals | January 21, 2023 | September 21, 2023 |
| NCT01372072 | Completed | N/A | A Study to Investigate the Effects of Heated Humidification During Non-Invasive Ventilation | February 1, 2012 | September 30, 2014 |
| NCT00742248 | Completed | Phase 2 | Formoterol Via pMDI HFA-134a Propellant or DPI in Partially Reversible Chronic Obstructive Pulmonary Disease (COPD) | September 2004 | May 2005 |
| NCT06054048 | Completed | N/A | Open Video System in Medicine (oVID) | February 1, 2019 | February 28, 2022 |
| NCT00000568 | Completed | Phase 3 | Lung Health Study (LHS) I and III | September 1984 | January 2005 |
| NCT01797367 | Completed | Pulmonary Substudy: A Substudy of Strategic Timing of AntiRetroviral Treatment (START) | March 2010 | December 31, 2016 | |
| NCT02023554 | Completed | N/A | Drug Interaction Study of Azithromycin and Theophylline | December 2013 | July 2014 |
| NCT00898859 | Completed | Role of A Disintegrin and Metalloproteinase (ADAM) in Epithelial Dysfunction | May 2009 | December 2012 | |
| NCT04966052 | Completed | COPD Co-infection With Tuberculosis on Th17 Cell Differentiation | April 1, 2018 | June 1, 2020 | |
| NCT03611127 | Completed | N/A | The Impact of Early Pulmonary Rehabilitation on Multidimensional Aspect of Dyspnea in COPD Patients After Exacerbation | April 15, 2016 | August 20, 2017 |
| NCT04341753 | Completed | N/A | Intra- and Inter-evaluator Reproducibility of Upper Limb Strength Measures in Patients With COPD | September 14, 2020 | September 9, 2021 |
| NCT02750189 | Completed | The Economic Burden of Chronic Obstructive Pulmonary Disease(COPD) in South Korea | September 2015 | January 2017 | |
| NCT01376830 | Completed | Characteristics That Identify Exacerbation Risk Following Colds in COPD Patients | June 2011 | June 2013 | |
| NCT02611531 | Completed | N/A | Video vs. TTG Respiratory Inhaler Technique Assessment and InstructioN (V-TRaIN) | November 2015 | September 2017 |
| NCT03806868 | Completed | N/A | Dietary Intervention Increasing Omega-3 Intake | January 23, 2019 | February 21, 2020 |
| NCT00959855 | Completed | N/A | Long-term Impact of Pulmonary Rehabilitation | September 2009 | September 2011 |
| NCT00774176 | Completed | Pennsylvania Study Of Chronic Obstructive Pulmonary Exacerbations | June 2004 | May 2008 | |
| NCT00545922 | Completed | Phase 2 | Cognitive Behavioral Therapy for Anxiety and Depression in COPD | April 2005 | November 2007 |
| NCT01513460 | Completed | Phase 3 | Efficacy, Tolerability and Safety of NVA237 in Patients With Chronic Obstructive Pulmonary Disease | April 2012 | December 2013 |
| NCT00126776 | Completed | N/A | Veterans Integrated Service Network (VISN) 23 Lung Disease Self Management/Case Management Program | July 2004 | July 2008 |
| NCT02740465 | Completed | N/A | Anxiety and COPD Evaluation | January 2016 | March 1, 2019 |
| NCT02651935 | Completed | N/A | Intellivent ASV in Chronic Obstructive Pulmonary Disease Patients in the ICU | August 2015 | February 2019 |
| NCT03152149 | Completed | Phase 4 | INvestigating COPD Outcomes, Genomics and Neutrophilic Inflammation With Tiotropium and Olodaterol | June 1, 2017 | November 26, 2019 |
| NCT00754546 | Completed | Phase 4 | Effect of Bronchodilation on Cycle vs Treadmill Exercise Endurance Time in COPD | August 2008 | May 2009 |
| NCT01566968 | Completed | Novel Endpoints in Cough Challenge Testing | January 2011 | April 2012 | |
| NCT01946620 | Completed | Phase 3 | A Study to Show That Flutiform is Well Tolerated and Effective in the Treatment of COPD | October 2013 | May 2016 |
| NCT03888131 | Completed | Phase 3 | Foster® pMDI (CHF 1535) Versus Symbicort® Turbohaler in COPD Patient | July 30, 2018 | May 6, 2022 |
| NCT00839735 | Completed | Trefoil Peptides in Lung Diseases | February 2009 | May 2010 | |
| NCT04256070 | Completed | N/A | Effect of Education and Tele-consultancy Intervention Based on Watson Human Care Theory Individuals With COPD | October 1, 2020 | June 21, 2022 |
| NCT02740686 | Completed | Changes in Inflammatory Markers During Pulmonary Rehabilitation Based on Exacerbation States in COPD | July 2016 | August 28, 2018 | |
| NCT03177811 | Completed | Phase 4 | Effect of Acetazolamide on Postural Control in Patients With Respiratory Disease at Altitude | May 24, 2017 | August 2, 2018 |
| NCT02746536 | Completed | N/A | Slow Chest Compression on Dynamic Hyperinflation, Dyspnea and Peripheral Muscle Deoxygenation in Patients With COPD | July 2016 | March 2018 |
| NCT02457455 | Completed | Urgent Medical and Surgical Conditions During Flights | October 2014 | January 2015 | |
| NCT01016587 | Completed | Symptom Clusters and Immune Markers in Patients With Chronic Obstructive Pulmonary Disease (COPD) - a Longitudinal Study | November 2009 | February 2014 | |
| NCT02232126 | Completed | N/A | Social Work Intervention Focused on Transitions | February 2011 | October 2013 |
| NCT01741480 | Completed | N/A | Early Warning System | February 2013 | May 2013 |
| NCT00250679 | Completed | Phase 3 | Safety and Efficacy of Arformoterol Tartrate Inhalation Solution in Subjects With Chronic Obstructive Pulmonary Disease | October 2005 | October 2007 |
| NCT04978831 | Completed | N/A | The Effect of Use of Breathing Exercise Device and Reading Aloud on Vital Signs | November 1, 2020 | January 31, 2022 |
| NCT01096303 | Completed | Effects of Marijuana Used on Lung Function in Persons With Chronic Obstructive Pulmonary Disease (COPD) | November 2010 | December 31, 2016 | |
| NCT00062582 | Completed | Phase 3 | Effect of Roflumilast on Pulmonary Function and Respiratory Symptoms in Patients With Chronic Obstructive Pulmonary Disease (COPD) (BY217/M2-110) | June 2003 | |
| NCT00076089 | Completed | Phase 3 | OPUS Study: Effect of Roflumilast on Exacerbation Rate in Patients With Chronic Obstructive Pulmonary Disease (BY217/M2-111) | December 2003 | December 2005 |
| NCT01648621 | Completed | N/A | Program of Integrated Care for Patients With Chronic Obstructive Pulmonary Disease and Multiple Comorbidities | August 2012 | December 2015 |
| NCT02125734 | Completed | Phase 4 | Lung Function and Patient Preference With QVA149 vs. Tiotropium in COPD Patients | April 2014 | January 2015 |
| NCT01703624 | Completed | Phase 2 | Dose Ranging Study of Glycopyrronium Bromide in Patients With Moderate or Severe Chronic Obstructive Pulmonary Disease | May 2013 | September 2013 |
| NCT02951312 | Completed | Phase 2 | Assessment of the Safety and Ability of a Once-a-day Dose of an Orally Inhaled Medicine [ie, Glycopyrrolate Inhalation Solution = GIS] to Improve Airflow in the Lungs When Delivered With an Electronic eFlow Nebulizer System in Patients With Chronic Obstructive Pulmonary Disease (COPD) | May 2009 | July 2009 |
| NCT00424528 | Completed | Phase 4 | Efficacy Safety Study of Arformoterol/Tiotropium Combination Versus Either Therapy Alone in Chronic Obstructive Pulmonary Disease (COPD) | December 2006 | October 2007 |
| NCT03137992 | Completed | Phase 3 | Clinical Endpoint Bioequivalence Study of Test and Reference Inhalation Products in Patients With COPD With Device Robustness | November 21, 2017 | April 30, 2018 |
| NCT01113138 | Completed | N/A | Study of the Metabolism of Two Magnesium Supplements in Healthy Volunteers | December 2012 | January 2014 |
| NCT01271556 | Completed | N/A | Effect of Salmeterol on Fluid Clearance From Alveolar-Capillary Membrane in COPD Patients | December 2008 | July 2009 |
| NCT01186653 | Completed | Phase 4 | Effect on Adrenal Function of Budesonide Versus Fluticasone in Chronic Obstructive Pulmonary Disease (COPD) | October 2007 | May 2010 |
| NCT00403845 | Completed | Phase 2 | Dose Ranging Study of Indacaterol in Japanese Patients With Chronic Obstructive Pulmonary Disease (COPD) | December 2006 | October 2007 |
| NCT04127383 | Completed | N/A | Effectiveness and Implementation of the Assessment of Burden of Chronic Conditions (ABCC)-Tool | November 1, 2019 | November 1, 2022 |
| NCT00800072 | Completed | N/A | NOWOX Oxygen Therapy Monitoring Device | November 2008 | February 2010 |
| NCT00791505 | Completed | Phase 3 | Antibiotic/COPD in Acute Exacerbation of Chronic Obstructive Pulmonary Disease (COPD) Requiring Mechanical Ventilation | July 2002 | June 2005 |
| NCT00832611 | Completed | Phase 4 | Study of the Effect of the ROX AC1 on Exercise Capacity and Quality of Life in Chronic Obstructive Pulmonary Disease (COPD) Patients | November 2008 | November 2011 |
| NCT00740220 | Completed | Reproducibility of 6 Minute Walk Tests for Oxygen Desaturation | September 2006 | January 2009 | |
| NCT03906045 | Completed | Phase 1 | A Scintigraphy Study of PT010 in COPD Patients | April 4, 2019 | March 5, 2020 |
| NCT02001935 | Completed | N/A | Association Between CytochromeP4501A2 and CytochromeP4502E1 Gene Polymorphisms and Metabolism of Theophylline | September 2013 | July 2014 |
| NCT01966107 | Completed | Phase 4 | Evaluate the Effect of Aclidinium Bromide on Long-term Cardiovascular Safety and Exacerbations in Moderate to Very Severe COPD Patients. | October 16, 2013 | September 21, 2017 |
| NCT01437397 | Completed | Phase 3 | Efficacy, Safety and Tolerability of Aclidinium Bromide/Formoterol Fumarate Compared With Aclidinium Bromide and Formoterol Fumarate in Patients With Moderate to Severe Chronic Obstructive Pulmonary Disease (COPD) | September 2011 | February 2013 |
| NCT00005284 | Completed | Epidemiology of Airway Responsiveness | January 1985 | March 2002 | |
| NCT00005123 | Completed | Honolulu Heart Program | July 1965 | September 2002 | |
| NCT01977469 | Completed | N/A | Randomized Controlled Study to Investigate the Impact of Different Intensities Training on ADL and BODE Index in COPD | December 2013 | December 2016 |
| NCT01169727 | Completed | Observational Study to Evaluate Health Status of Chronic Obstructive Pulmonary Disease (COPD) Patients in Response to Real-life Treatments in Thailand | July 2010 | March 2012 | |
| NCT01418768 | Completed | N/A | Effects of an Inpatient Rehabilitation for Patients With Chronic Obstructive Pulmonary Disease (COPD) III/IV | August 2011 | December 2012 |
| NCT01372462 | Completed | N/A | Effects of the Breathe Technologies Ventilation System in Subjects With Chronic Obstructive Pulmonary Disease | July 2011 | May 2012 |
| NCT00864786 | Completed | Phase 1 | Multiple Dose Healthy Volunteer Safety Pharmacokinetics Study | September 2008 | March 2009 |
| NCT02979379 | Completed | Pain in Individuals With COPD During Pulmonary Rehabilitation | April 2016 | March 3, 2020 | |
| NCT01833026 | Completed | N/A | COPD Assessment and Management Bundle Versus Usual Care | March 2013 | May 2016 |
| NCT05690217 | Completed | The Difference in the Biological Characteristic Characteristics of the Heart and Lung Meridians | January 1, 2019 | December 31, 2021 | |
| NCT02599883 | Completed | N/A | Evidence-based Analysis of Low-dose CT in Management of COPD | September 2012 | September 2015 |
| NCT01058213 | Completed | Phase 2 | Nurse Managed Sequential Strength Training and Bicycle Training in Chronic Obstructive Pulmonary Disease (COPD) | November 2008 | May 2013 |
| NCT01819298 | Completed | Bacterial Colonization in COPD in View of CAT Under ICS+LABA Therapy | March 2011 | June 2012 | |
| NCT05431218 | Completed | Phase 4 | Association of Cathelicidin and Vitamin D Levels With the Category and Course of COPD | February 18, 2020 | December 31, 2021 |
| NCT01215279 | Completed | Phase 2 | AZD2423 Safety and Tolerability Study in Patients With Moderate and Severe Chronic Obstructive Pulmonary Disease(COPD) | October 2010 | March 2011 |
| NCT01078623 | Completed | Phase 2 | Efficacy and Safety of Two Fixed Dose Combinations of Aclidinium Bromide With Formoterol Fumarate | February 2010 | September 2010 |
| NCT01071161 | Completed | Phase 3 | The Effect of Azithromycin in Patients With Chronic Obstructive Pulmonary Disease (COPD) and Chronic Productive Cough | September 2009 | February 2012 |
| NCT04873856 | Completed | N/A | Multidimensional Individualized Nutritional Therapy for Individuals With Severe COPD | May 21, 2021 | June 14, 2023 |
| NCT00571428 | Completed | Phase 4 | Efficacy Safety Study of Arformoterol QD Dosing Versus BID Dosing in COPD | November 2007 | March 2008 |
| NCT01088633 | Completed | N/A | Characterization of Aerosol Generation and Transport in the Human Lung of Subjects With Chronic Obstructive Pulmonary Disease (COPD) | March 2010 | September 2010 |
| NCT04120142 | Completed | N/A | Effect of Inspiratory Muscle Training During PR on Dyspnoea and Exercise Tolerance in COPD Patients | February 1, 2019 | December 1, 2019 |
| NCT00637299 | Completed | Early Phase 1 | Osteopathy in Chronic Obstructive Pulmonary Disease (COPD) Rehabilitation Trial | January 2008 | November 2008 |
| NCT05258175 | Completed | N/A | Effects of Kinesiotaping Technique on Lung Function & Functional Capacity of Chronic Obstructive Lung Disease Patients | September 15, 2022 | December 28, 2022 |
| NCT05373953 | Completed | Phase 1 | Clinical Study to Investigate the Pharmacokinetics, Safety and Tolerability Following Single Administration of CHF6001 in Subjects With Mild, Moderate and Severe Liver Impairment in Comparison With Matched Healthy Control Subjects | May 5, 2022 | November 25, 2022 |
| NCT00801307 | Completed | Phase 1/Phase 2 | Trial Comparing Effect of He/O2 to Medical Air on Pulmonary Function Disease | June 2008 | March 2010 |
| NCT04421742 | Completed | The Effect of Beclomethasone/Formoterol in Extra-fine Formulation on Quality of Life and SAD in COPD Patients. | May 31, 2017 | May 23, 2019 | |
| NCT01332097 | Completed | Phase 2 | Safety & Efficacy of BCT197A2201 in COPD Patients Presenting With an Exacerbation | March 2011 | May 2013 |
| NCT04414267 | Completed | Phase 4 | Bacillus Calmette-guérin Vaccination to Prevent COVID-19 | May 26, 2020 | May 7, 2021 |
| NCT02694796 | Completed | N/A | Impact of Web and Smartphone-based Physical Activity Program on Physical Activity Level 12 Months After a Balneotherapy | September 2015 | December 20, 2017 |
| NCT03198780 | Completed | N/A | Mindful Breathing Awareness Through Pursed-Lip Breathing Training | October 1, 2018 | July 31, 2019 |
| NCT01349803 | Completed | Phase 2 | PT003 MDI Cardiovascular Safety Study | May 2011 | November 2011 |
| NCT02282189 | Completed | N/A | Longitudinal Study of Oscillatory Positive Expiratory Pressure (oPEP) in Stable COPD | July 2012 | January 2013 |
| NCT00777595 | Completed | Phase 1 | Evaluation of Possible Effects on the QTc Interval of CHF 4226 pMDI in Healthy Volunteers | October 2008 | December 2008 |
| NCT01226836 | Completed | N/A | Pulmonary Rehabilitation in Chronic Obstructive Pulmonary Disease (COPD): the Development and Feasibility of an Education Package | January 2010 | October 2010 |
| NCT03110614 | Completed | Diastolic Dysfunction and Pauci-inflammatory Acute Exacerbations of COPD | November 25, 2013 | August 30, 2021 | |
| NCT04014868 | Completed | N/A | During-exercise Physiological Effects of Nasal High-flow in Patients With Chronic Obstructive Pulmonary Disease | November 22, 2019 | October 10, 2021 |
| NCT01197469 | Completed | Phase 2 | Do Phosphodiesterase 5A Inhibitors Improve Exercise Capacity in Patients With Chronic Obstructive Pulmonary Disease (COPD) and Pulmonary Hypertension? | September 2010 | September 2012 |
| NCT04540042 | Completed | Phase 2 | Study to Assess the Safety and Efficacy of SelK2 on Airway Responses Following Allergen Challenge in Subjects With Asthma (Part 1) and in Subjects With Chronic Obstructive Pulmonary Disease (Part 2) | August 18, 2020 | January 13, 2022 |
| NCT01721291 | Completed | Phase 4 | Inhaler Lung Deposition in Chronic Obstructive Pulmonary Disease (COPD) | October 1, 2012 | November 27, 2017 |
| NCT02244957 | Completed | N/A | Right Ventricular Hemodynamics Using Cardiac MRI in Patients COPD and OSA | September 2014 | February 2020 |
| NCT04026529 | Completed | N/A | Uphill Walking as Exercise for COPD Patients | January 6, 2020 | September 30, 2022 |
| NCT03646864 | Completed | Phase 1 | A Study to Evaluate the Effects of ACT-541468 on Respiration in Patients With Moderate Chronic Obstructive Pulmonary Disease | November 15, 2018 | September 19, 2019 |
| NCT01435538 | Completed | N/A | European Quality of Care Pathways Study on the Effect of Care Pathways on Interprofessional Teamwork (EQCP-TEAM) | May 2009 | January 2017 |
| NCT03157986 | Completed | N/A | Effects of Whole-Body Vibration Training Versus Balance Training in Patients With Severe Chronic Obstructive Pulmonary Disease | May 15, 2017 | August 16, 2019 |
| NCT01566773 | Completed | Phase 2 | PT001 MDI Versus Spiriva® in Patients With Moderate to Severe COPD | March 2012 | August 2012 |
| NCT03068026 | Completed | N/A | Influence of the VitaBreath on Exercise Tolerance in COPD | June 6, 2017 | September 30, 2018 |
| NCT02557178 | Completed | N/A | Home-Based Health Management of COPD Patients | September 2016 | March 2019 |
| NCT00966459 | Completed | N/A | Computed Tomography (CT) and Lung Function Data Collection for Computational Fluid Dynamics (CFD) in Chronic Obstructive Pulmonary Disease (COPD) Patients | November 2008 | May 2009 |
| NCT01852006 | Completed | N/A | Abdominal Binding in Chronic Obstructive Pulmonary Disease | January 2014 | May 2015 |
| NCT01363531 | Completed | Phase 4 | Clinical Trial for the Assessment of Delayed Antibiotic Treatment Strategies | December 2009 | August 2012 |
| NCT03405090 | Completed | Phase 4 | Differential Mechanisms of Dyspnea Relief in Advanced COPD: Opiates vs. Bronchodilators | September 20, 2017 | March 31, 2023 |
| NCT00561886 | Completed | Phase 4 | Change of Inspiratory Peak Flow in COPD | April 2007 | October 2007 |
| NCT02814656 | Completed | Phase 1 | Safety, Tolerability and Pharmacokinetics of Multiple Ascending Doses of AZD8871 in Healthy Subjects | June 22, 2016 | November 28, 2016 |
| NCT02972775 | Completed | 15-year Mortality After Hospitalization for Exacerbation of Chronic Obstructive Pulmonary Disease | January 2005 | October 2017 | |
| NCT02143206 | Completed | Modifying Exercise for the COPD Patient | September 2012 | May 2014 | |
| NCT00441389 | Completed | Infectious Etiology of Acute Exacerbations of COPD | May 2004 | December 2007 | |
| NCT01044628 | Completed | N/A | The International Nocturnal Oxygen (INOX) Trial | October 2010 | January 2019 |
| NCT01854645 | Completed | Phase 3 | Efficacy and Safety of PT003, PT005, and PT001 in Subjects With Moderate to Very Severe Chronic Obstructive Pulmonary Disease (COPD); (PINNACLE 1) | May 2013 | February 2015 |
| NCT02490657 | Completed | N/A | Effects of Iloprost on Pulmonary Hemodynamics and Oxygenation in Patients of Chronic Obstructive Pulmonary Disease During One-lung Ventilation | July 2015 | May 2016 |
| NCT03216603 | Completed | N/A | Health Literacy in People With Chronic Obstructive Pulmonary Disease | November 1, 2017 | December 31, 2020 |
| NCT01715298 | Completed | Phase 3 | NVA237 BID Versus Placebo Twelve-week Efficacy Study | November 2012 | December 2013 |
| NCT02187926 | Completed | Evaluation of Clinical Effectiveness of Roflumilast in Routine Practice, in Chronic Obstructive Pulmonary Disease (COPD) Patients in Greece | May 2011 | December 2013 | |
| NCT00890136 | Completed | Chronic Obstructive Pulmonary Disease (COPD) and Domestic Endotoxin (CODE) | July 2008 | November 2014 | |
| NCT01985529 | Completed | N/A | A Controlled Study of Community-based Exercise Training in Patients With Moderate COPD | December 2008 | |
| NCT01426009 | Completed | Phase 2 | Study to Investigate the Dose Response, Safety and Efficacy of Nebulized EP-101(SUN101) in Patients With Chronic Obstructive Pulmonary Disease (COPD): GOLDEN-1 Study | August 2011 | December 2011 |
| NCT01167283 | Completed | N/A | Effect of Electrostimulation in Chronic Obstructive Pulmonary Disease (COPD) | July 2006 | April 2010 |
| NCT02586948 | Completed | N/A | Physiological Study of Minimally Invasive ECCO2R in Exacerbations of COPD Requiring Invasive Mechanical Ventilation | July 2016 | February 12, 2018 |
| NCT03280355 | Completed | N/A | The Effects of Singing Training for Patients With Chronic Obstructive Pulmonary Disease (COPD) | August 1, 2017 | April 15, 2019 |
| NCT00692198 | Completed | Phase 3 | Long-term Oxygen Treatment Trial | January 2009 | August 2015 |
| NCT00908765 | Completed | N/A | Effects of Aerobe Interval Training and Moderate Continuous Training in Chronic Obstructive Pulmonary Disease Patients | August 2008 | September 2009 |
| NCT00737698 | Completed | N/A | Comparison of Repetitive Magnetic Stimulation and Exercise on Quadriceps Function in COPD | January 2007 | October 2010 |
| NCT01058499 | Completed | Phase 1 | Mindfulness Based Stress Reduction in COPD | February 2010 | December 2010 |
| NCT02300090 | Completed | A Real-World Assessment of a COPD Disease Management Support Service (Me & My COPD) | October 26, 2016 | August 23, 2018 | |
| NCT05168241 | Completed | N/A | The Effect of Singing or Playing Melodica in COPD Patients | September 1, 2020 | August 31, 2021 |
| NCT02266875 | Completed | Phase 4 | Nebulized Hypertonic Saline for Inpatient Use in COPD | October 2014 | January 30, 2017 |
| NCT00105846 | Completed | Phase 2 | An Evaluation of Home-Based Telemedicine Services | June 2004 | |
| NCT01263808 | Completed | Phase 1 | Cardiac Safety of Indacaterol | April 2008 | |
| NCT00215423 | Completed | Phase 2 | Study in Patients With COPD | September 2005 | |
| NCT01175265 | Completed | Phase 1 | Effects of Breathing Retraining in Patients With Chronic Obstructive Pulmonary Disease (COPD) | November 2008 | April 2010 |
| NCT02618746 | Completed | N/A | Home Rehabilitation Via Telemonitoring in Patients With COPD | December 2013 | July 2016 |
| NCT03930732 | Completed | Phase 3 | Pivotal Study to Assess the Efficacy, Safety and Tolerability of Dupilumab in Patients With Moderate-to-severe COPD With Type 2 Inflammation | April 15, 2019 | May 2, 2023 |
| NCT05776654 | Completed | Wearable Devices in the Recovery Phase of Acute Exacerbations of COPD (AECOPDs) | February 16, 2023 | January 15, 2024 | |
| NCT03871933 | Completed | Autonomic Function in COPD and Risk for Atrial Fibrillation | March 1, 2019 | August 31, 2019 | |
| NCT00977873 | Completed | Phase 2/Phase 3 | Trial of Vitamin D Supplementation in Chronic Obstructive Pulmonary Disease | September 2009 | July 2013 |
| NCT00546299 | Completed | N/A | Gas Usage for Those With COPD Who Experience Low Oxygen Levels During Activities Only | February 2003 | December 2005 |
| NCT02036294 | Completed | N/A | Improving Patient-Centered Care Delivery Among Patients With Chronic Obstructive Pulmonary Disease | March 10, 2015 | January 9, 2017 |
| NCT01327456 | Completed | N/A | The Effects of a Self-management Intervention on Low Literacy Patients With Chronic Obstructive Pulmonary Disease (COPD) | January 2008 | December 2008 |
| NCT00429156 | Completed | Phase 3 | Non-invasive Ventilation Versus Sham Ventilation in Chronic Obstructive Pulmonary Disease (COPD) | January 2007 | February 2009 |
| NCT00435708 | Completed | Phase 1 | Effect of Increased Fruit and Vegetable Intake on Chronic Obstructive Pulmonary Disease (COPD) | February 2007 | September 2009 |
| NCT01852656 | Completed | N/A | Effectiveness of Influenza Vaccine Reminder Systems | September 2012 | April 2013 |
| NCT03590379 | Completed | Phase 2 | Efficacy of Fixed Combination of Beclomethasone Dipropionate (BDP) + Formoterol Fumarate (FF) + Glycopyrronium Bromide (GB) (CHF 5993)Administered Via Dry Powder Inhaler (DPI) in Chronic Obstructive Pulmonary Disease (COPD) | June 15, 2018 | March 6, 2019 |
| NCT01696916 | Completed | N/A | Development of the Partial Pressure of Carbon Dioxide During Exercise and at Night in Patients With Chronic Obstructive Pulmonary Disease (COPD) IV | March 2012 | February 2014 |
| NCT02613351 | Completed | N/A | Muscle Activity and Sensation During Upright Partitioned Leg Exercise in COPD | December 2015 | August 14, 2017 |
| NCT01786928 | Completed | N/A | The Role of Resistance Exercise in Chronic Obstructive Pulmonary Disease Exacerbation | April 2009 | October 2010 |
| NCT00908362 | Completed | Phase 1 | Impact of Fluticasone and Salmeterol on Airway Dendritic Cells (DCs) in Smokers | May 2009 | December 2009 |
| NCT00531050 | Completed | Phase 2 | Safety of Exercise and High-dose Salbutamol in Patients With Chronic Obstructive Pulmonary Disease (COPD) Receiving Therapeutic Doses of Indacaterol (QAB 149) and Salmeterol | August 2007 | June 2008 |
| NCT00354354 | Completed | Phase 4 | Bronchodilators and Oxygen Kinetics With Exercise in Chronic Obstructive Pulmonary Disease (COPD) Patients | March 2006 | July 2009 |
| NCT01749462 | Completed | Oxis 9mcg Turbuhaler Clinical Experience Investigation | February 2013 | July 2015 | |
| NCT01728220 | Completed | Phase 2 | Two-Part Dose-Confirming Study of Pulsed Inhaled Nitric Oxide in Subjects With WHO Group 3 Pulmonary Hypertension Associated With COPD | December 2012 | July 2014 |
| NCT01354782 | Completed | Phase 1 | Pharmacokinetic Study of Single and Repeated Dose of Roflumilast 500 µg , in Healthy Chinese Subjects | May 2011 | September 2011 |
| NCT04231214 | Completed | Phase 4 | Effects of Spiolto® Respimat® (Tiotropium/Olodaterol) on Cardiac Function in Hyperinflated COPD Subjects | January 28, 2020 | April 18, 2023 |
| NCT03796455 | Completed | N/A | Fish Oil and HMB Supplementation in COPD | April 25, 2018 | April 1, 2020 |
| NCT01197287 | Completed | Phase 1 | Safety, Tolerability and Pharmacokinetics of QAK423A in Healthy Volunteers and Chronic Obstructive Pulmonary Disease (COPD) Patients | May 2004 | |
| NCT00006513 | Completed | Assessing the Occupation Burden in COPD | September 2000 | August 2004 | |
| NCT01322594 | Completed | Phase 1 | A Study to Evaluate the Safety of MEDI2338 in Subjects With Chronic Obstructive Pulmonary Disease | March 2011 | December 2011 |
| NCT02314338 | Completed | N/A | The Short Physical Performance Battery in Chronic Obstructive Pulmonary Disease (COPD) | September 2014 | December 2015 |
| NCT03446768 | Completed | N/A | Monitoring and Peer Support to Improve Treatment Adherence and Outcomes | February 1, 2018 | October 31, 2019 |
| NCT03591562 | Completed | Imaging Progression of Chronic Obstructive Pulmonary Disease Using MRI and CT (MR-COPDII) | November 10, 2017 | April 30, 2024 | |
| NCT01154127 | Completed | Phase 3 | Effect of NVA237 on Exercise Endurance in Patients With Chronic Obstructive Pulmonary Disease (COPD) | June 2010 | February 2011 |
| NCT02380053 | Completed | Phase 4 | Chronic Beta-blockade and Cardiopulmonary Exercise in COPD | June 7, 2016 | April 30, 2019 |
| NCT01402297 | Completed | Phase 1 | Hydrogen Peroxide and Nitrite Reduction in Exhaled Breath Condensate of COPD Patients | October 2010 | April 2011 |
| NCT01870830 | Completed | N/A | Nocturnal Breathing and Sleep in Patients With Chronic Obstructive Pulmonary Disease Staying at Altitude | June 2013 | December 2013 |
| NCT02593357 | Completed | N/A | Peripheral Endothelial Function in COPD Patients | December 17, 2012 | August 17, 2017 |
| NCT01119937 | Completed | Phase 3 | Long Term Safety and Tolerability of NVA237 Versus Tiotropium in Japanese Patients | May 2010 | |
| NCT00826163 | Completed | Phase 3 | Innate Immune Responses in Chronic Obstructive Pulmonary Disease (COPD) Patients | January 2009 | December 2009 |
| NCT02186340 | Completed | N/A | Effects of Inspiratory Muscle Training on Breathing Pattern in Patients With Chronic Obstructive Pulmonary Disease | January 2013 | July 2015 |
| NCT02109172 | Completed | Phase 2 | A 7-Day Cross-over Study of QD (Once Daily) and BID (Twice Daily) TD-4208 in Chronic Obstructive Pulmonary Disease (COPD) | April 2014 | October 2014 |
| NCT03522376 | Completed | Inspiratory Muscle Activation Patterns in Patients With Chronic Obstructive Pulmonary Disease | April 24, 2018 | December 20, 2018 | |
| NCT00628862 | Completed | Phase 3 | Evaluation of Efficacy and Safety of Formoterol in Patients With COPD Compared With Placebo in Patients in Japan, EU | December 2007 | April 2009 |
| NCT00559910 | Completed | Phase 2 | A Phase II, Study To Evaluate The Efficacy And Safety Of PH-797804 In Adults With Moderate To Severe Chronic Obstructive Pulmonary Disease (COPD). | February 2008 | December 2009 |
| NCT01222442 | Completed | Phase 1 | To Evaluate the Effect of AZD3199 on the Electrical Activity in the Heart | November 2010 | February 2011 |
| NCT02195375 | Completed | Phase 2/Phase 3 | Flutiform® Compared With Seretide® in the Treatment of COPD | September 2014 | May 2016 |
| NCT04606901 | Completed | Phase 4 | Comparison of Time to Extubation Using Sugammadex or Neostigmine | April 8, 2021 | July 30, 2023 |
| NCT01107613 | Completed | N/A | The Lung Attack Alert Study | January 2011 | January 2013 |
| NCT01285167 | Completed | Quality of Life in Daxas-treated Patients Older Than 18 Years With Severe Chronic Obstructive Pulmonary Disease (COPD) (DACOTA) | August 2010 | February 2012 | |
| NCT00394940 | Completed | Identifying Inflammatory Biomarkers of Chronic Obstructive Pulmonary Disease | July 2006 | January 2013 | |
| NCT05477108 | Completed | Phase 1 | Study to Assess the Lung Exposure Bioequivalence of Budesonide, Glycopyrronium, and Formoterol Delivered by BGF MDI HFO Compared With BGF MDI HFA | July 29, 2022 | April 11, 2023 |
| NCT02267655 | Completed | Phase 1 | 3 Part Study to Assess Inhaled Nitric Oxide on Functional Pulmonary Imaging in Subj. Pulmonary Hypertension Associated w/ COPD and IPF | May 2015 | June 28, 2017 |
| NCT00005370 | Completed | Longitudinal Study of Cortisol and Pulmonary Function | April 1993 | March 1999 | |
| NCT06135701 | Completed | N/A | Femoral Artery Blood Flow During Rest and One-leg Knee Extensor Exercise in Patients With COPD | November 21, 2023 | January 12, 2024 |
| NCT03567772 | Completed | N/A | Videogame Assisted Pulmonary Rehabilitation in Patients With Chronic Obstructive Pulmonary Disease | February 1, 2014 | July 30, 2014 |
| NCT02999685 | Completed | N/A | Home-based Health Management of Chronic Obstructive Lung Disease (COPD) Patients | September 2016 | June 2019 |
| NCT00063453 | Completed | Phase 3 | Supplemental Selenium and Vitamin E and Pulmonary Function | August 2003 | August 2010 |
| NCT01342263 | Completed | N/A | Trial of an Internet-based Platform for Managing Chronic Diseases at a Distance | May 2011 | September 2018 |
| NCT00958919 | Completed | N/A | Role of Endorphins in Perception of Dyspnea With Resistive Loading in Chronic Obstructive Pulmonary Disease (COPD) | August 2009 | October 2010 |
| NCT05610514 | Completed | Phase 2 | Pulmonary and Cardiac Effects of E-Cigarette Use in Pulmonary Patients Who Smoke Cigarettes | April 28, 2022 | December 1, 2023 |
| NCT05516316 | Completed | Phase 1 | Clinical Trial Comparing the Pharmacological Effects of EP395 With Placebo in Healthy Adults | October 11, 2022 | June 21, 2023 |
| NCT00766415 | Completed | Phase 2 | 14729-D9831C00002- 1 Month Biopsy Study | November 2008 | June 2009 |
| NCT03646851 | Completed | N/A | Aspergillus and Chronic Obstructive Pulmonary Disease Evolution | March 15, 2018 | March 15, 2019 |
| NCT02307799 | Completed | A RESearch on the PrEvalence and the Diagnosis of COPD and Its Tobacco-related Etiology | June 2012 | January 2019 | |
| NCT00752414 | Completed | Phase 1 | A Phase 1b Study to Evaluate the Safety and PK of MP-376 in Chronic Obstructive Pulmonary Disease (COPD) Patients | July 2008 | October 2008 |
| NCT01713075 | Completed | Symbicort Turbuhaler 30/60 Special Clinical Experience Investigation for Long-term Use for Chronic Obstructive Pulmonary Disease (COPD) Patients | November 2012 | December 2015 | |
| NCT00900731 | Completed | Phase 3 | A Study to Compare the Lung Effect of Indacaterol and Tiotropium in Chronic Obstructive Pulmonary Disease (COPD) | June 2009 | March 2010 |
| NCT00835289 | Completed | N/A | The Chronic Obstructive Pulmonary Disease Fish Oil Pilot Trial | March 2009 | August 2013 |
| NCT00005697 | Completed | Intervention for Resistant Pregnant Smokers | January 1993 | December 1996 | |
| NCT04010825 | Completed | N/A | Impact of Hypnosis Intervention on the Emotional Dimension of Dyspnea in Patients With COPD. | October 25, 2019 | February 29, 2024 |
| NCT05417503 | Completed | N/A | Non Invasive Ventilation on Peripheral Muscle Function and Aerobic Performance | December 1, 2017 | February 28, 2018 |
| NCT01481506 | Completed | N/A | Multiparametric Telemonitoring In Elderly People With Chronic Obstructive Pulmonary Disease | January 2010 | June 2011 |
| NCT02214056 | Completed | Mobile Unit Screening of Pathologies Associated With Chronic Diseases - Feasibility | February 2015 | April 2015 | |
| NCT02077465 | Completed | Phase 1 | Safety, Tolerability, and Pharmacokinetics of Andecaliximab in Adults With Chronic Obstructive Pulmonary Disease (COPD) | March 11, 2014 | October 27, 2014 |
| NCT01099410 | Completed | Apoptotic Cell (AC) Uptake by Human Alveolar Macrophages (AM) | February 2010 | December 2015 | |
| NCT00239278 | Completed | Phase 2 | Budesonide / Formoterol in Treatment of Exacerbations of COPD | January 2001 | January 2005 |
| NCT02189577 | Completed | Phase 2 | Efficacy and Safety of Glycopyrrolate Bromide of COPD Patients | June 2014 | February 2015 |
| NCT01329276 | Completed | Phase 4 | Assess Particle Deposition and Acute Effects of Symbicort® Forte Turbohaler®) in COPD Patients. | June 2010 | January 2011 |
| NCT03089515 | Completed | N/A | Small Airway Chronic Obstructive Disease Syndrome Following Exposure to WTC Dust | September 7, 2017 | September 1, 2021 |
| NCT01378520 | Completed | Phase 4 | Effect of Ketoconazole on Breathlessness | June 2011 | February 2012 |
| NCT02272634 | Completed | Phase 2 | A Phase 2a Study to Assess Safety, Daily Symptoms, PK, and Biomarkers of YPL-001 in COPD Patients | June 4, 2015 | November 8, 2017 |
| NCT00005720 | Completed | Lay-Led Smoking Cessation Approach for Southeast Asian Men | September 1990 | August 1996 | |
| NCT00880724 | Completed | N/A | European Multi-center Post Market Study of the IBV Valve System | March 2007 | June 2010 |
| NCT06143358 | Completed | N/A | Treatment of Acute Exacerbation of Chronic Obstructive Pulmonary Disease With Qingkepingchuan Granules Clinical Observation of Phlegm-Heat and Lung Depletion | January 1, 2022 | July 7, 2023 |
| NCT01283984 | Completed | Phase 1 | AZD2115 Single Ascending Dose Study | January 2011 | August 2011 |
| NCT02522026 | Completed | Follow-up-study of COPD Patients and Healthy Controls for Evaluation of Predictive Non-coding RNA Biomarkers | August 2015 | March 2017 | |
| NCT00896584 | Completed | Exercise Pulseoximetry for Pre-flight Evaluation of Chronic Obstructive Pulmonary Disease (COPD) Patients | May 2009 | November 2010 | |
| NCT05456178 | Completed | Relationship Between Degree of Domestic Environmental Fungal Exposure and Clinical Symptoms of Patients With Chronic Obstructive Pulmonary Disease | July 23, 2021 | June 29, 2023 | |
| NCT02162095 | Completed | Is COPD a Risk Factor for Cardiovascular Disease? | June 2014 | December 2014 | |
| NCT02993172 | Completed | The Copenhagen City Heart Study | January 1976 | ||
| NCT02534831 | Completed | N/A | Manual Therapy in Chronic Obstructive Pulmonary Disease | March 2012 | January 2013 |
| NCT03207776 | Completed | N/A | An Evaluation of Post Discharge Utilization Among Patients With an Acute Exacerbation of COPD | June 12, 2017 | August 13, 2018 |
| NCT01048333 | Completed | Phase 2 | Evaluate Onset of Effect in Patients With Chronic Obstructive Pulmonary Disease (COPD) Treated With Formoterol Turbuhaler® | January 2010 | May 2010 |
| NCT00783991 | Completed | Investigating the Impact of Mode of Administration on Item Response | April 2009 | December 2009 | |
| NCT02238639 | Completed | N/A | Pulmonary Embolism as a Cause of COPD Exacerbations | October 2014 | December 2020 |
| NCT03660501 | Completed | Wireless Assessment of Respiratory and Circulatory Distress in Chronic Obstructive Pulmonary Disease - an Observational Study | September 12, 2018 | June 21, 2020 | |
| NCT00787748 | Completed | COPD and Cardiovascular Risk in the Population | October 2006 | June 2008 | |
| NCT00159367 | Completed | N/A | The Use of Repetitive Magnetic Stimulation for Strength Training of the Quadriceps Muscle | January 2005 | February 2006 |
| NCT02070133 | Completed | Phase 3 | Efficacy of Simvastatin for the Treatment of COPD | May 2009 | May 2013 |
| NCT02975843 | Completed | Phase 1 | Lung Deposition of Beclometasone Dipropionate/Formoterol Fumarate/Glycopyrronium Bromide Administered Via pMDI in Healthy, Asthmatic and COPD Patients | November 21, 2016 | April 11, 2017 |
| NCT01507844 | Completed | N/A | Continuous Positive Airway Pressure Effect on Air Trapping in Chronic Obstructive Pulmonary Disease Patients | November 2009 | June 2011 |
| NCT03899558 | Completed | N/A | The Role of HNHF to Improve Clinical Outcomes Following Severe AECOPD | June 17, 2019 | March 24, 2021 |
| NCT04966026 | Completed | Clinical Characteristics and Outcome of Patients With COPD With Pneumonia | March 1, 2017 | May 30, 2018 | |
| NCT00636961 | Completed | Phase 2 | An Exploratory Study, to Assess the Effect of Repeat-dose Inhaled Indacaterol Maleate (300 μg) on Dynamic and Static Lung Hyperinflation, Subjective Breathlessness and Health Status in Patients With Chronic Obstructive Pulmonary Disease(COPD) | February 2008 | August 2008 |
| NCT01154400 | Completed | N/A | Hydrolyzed Casein and Whey Protein Supplementation and the Addition of Leucine to Induce Protein Anabolism in Malnourished COPD Patients | May 2009 | July 2011 |
| NCT03310177 | Completed | Relationship Between Metabolic Profile and Clinical Phenotype in Chronic Obstructive Pulmonary Disease | December 10, 2015 | July 20, 2017 | |
| NCT03904875 | Completed | Air Pollution and COPD Exacerbation | January 1, 2020 | September 12, 2023 | |
| NCT00298389 | Completed | Macrophage Phagocytosis in COPD | October 2005 | December 2010 | |
| NCT01679314 | Completed | N/A | Study to Compare (COPD) Assessment Test in COPD Stage III and IV in a Prophylactic Treatment | July 2012 | May 2013 |
| NCT01917331 | Completed | Phase 3 | Efficacy of Fixed Combination of Beclometasone + Formoterol + Glycopyrrolate Versus Foster® in COPD | March 2014 | March 2016 |
| NCT01509703 | Completed | N/A | Respiratory Physiology Under High Flow Therapy | December 2011 | December 2014 |
| NCT03698682 | Completed | Phase 2 | Short Compared With Standard Duration of Antibiotic Treatment for AECOPD | January 1, 2018 | January 31, 2021 |
| NCT03527927 | Completed | N/A | sTep dOWn Inhalers in the reAl woRlD | May 17, 2017 | August 26, 2019 |
| NCT01627418 | Completed | N/A | Warm Homes for Elder New Zealanders | April 2009 | February 2013 |
| NCT01695265 | Completed | N/A | Feel Breathe, Restriction Device Ventilatory Nasal (COPD) | February 2012 | September 2015 |
| NCT03176745 | Completed | Number of Multiple Breath Washout Tests in Adults With Pulmonary Disease and Healthy Controls | July 1, 2015 | January 15, 2017 | |
| NCT05424133 | Completed | N/A | ACBT and High Frequency Chest Wall Oscillations in COPD Patients | March 15, 2022 | October 31, 2022 |
| NCT03853642 | Completed | Blood Eosinophil Measurements in Patients With Chronic Obstructive Pulmonary Disease | March 1, 2019 | March 28, 2020 | |
| NCT00707811 | Completed | Evaluation of ST2 and IL-33 in Patients Presenting to the Emergency Department With Trouble Breathing | April 2008 | June 2010 | |
| NCT00507234 | Completed | Phase 3 | Study in Subjects Greater Than 40 Years of Age With COPD | March 2007 | April 2008 |
| NCT01541852 | Completed | Phase 2 | Losmapimod in Chronic Obstructive Pulmonary Disease Patients Stratified by Fibrinogen. | June 2012 | February 2014 |
| NCT01419158 | Completed | Prevalence of Alpha-1 Antitrypsin Deficiency in Chronic Obstructive Pulmonary Disease (COPD) | January 2008 | January 2010 | |
| NCT03555097 | Completed | N/A | Effects of Non-invasive Ventilation on Respiratory Mechanics and NRD in Patients With Stable COPD | July 10, 2018 | March 1, 2019 |
| NCT02021955 | Completed | N/A | Integrating Care After Exacerbation of COPD | February 11, 2015 | January 31, 2019 |
| NCT02131454 | Completed | N/A | Efficacy of Inhalation Technique Training. | September 2013 | August 2016 |
| NCT03046199 | Completed | N/A | Detection of COPD in Primary Care | February 27, 2017 | October 4, 2019 |
| NCT01380470 | Completed | Prevalence of Undiagnosed Chronic Obstructive Pulmonary Disease Sufferers in the Region of Murcia | February 2010 | June 2010 | |
| NCT00175565 | Completed | Phase 4 | Inhaled Steroid Reduces Systemic Inflammation in COPD | January 2002 | July 2003 |
| NCT00180635 | Completed | N/A | NO Donors and Inhibitors to Study Imbalance of Nitrogen Stress and Antioxidant Defense in COPD | October 2003 | July 2006 |
| NCT05259280 | Completed | N/A | Observational Study of the Wellinks Solution Impact on Quality of Life and Clinical Outcomes in Patients With COPD | January 5, 2022 | September 8, 2022 |
| NCT01644916 | Completed | N/A | "Consultation Liaison and Integrated Care for COPD Patients With Psychiatric Co-Morbidity" | August 2012 | December 2017 |
| NCT05179512 | Completed | Replication of the INSPIRE Trial in Healthcare Claims Data | September 22, 2020 | August 30, 2021 | |
| NCT03008915 | Completed | Phase 2 | Targeting Pulmonary Perfusion in Alpha-1 Antitrypsin Deficiency | January 2017 | October 2020 |
| NCT04459143 | Completed | Chronic Obstructive Pulmonary Disease (COPD) and Advance Directives | May 16, 2019 | October 31, 2020 | |
| NCT01068600 | Completed | Phase 3 | Comparison of Efficacy of Indacaterol Versus Placebo Over 12 Weeks | January 2010 | |
| NCT01349816 | Completed | Phase 2 | PT003 MDI Dose Confirmation Study | June 2011 | November 2011 |
| NCT01045161 | Completed | Phase 3 | Efficacy, Safety, and Tolerability of Aclidinium Bromide in the Treatment of Moderate-to-severe Chronic Obstructive Pulmonary Disease (COPD) (LAS-MD-38) | March 2009 | June 2011 |
| NCT02948582 | Completed | Phase 2 | Assessment of the Safety and Ability of a Once-a-day Dose of an Orally Inhaled Medicine [i.e., Glycopyrrolate Inhalation Solution = GIS] to Improve Airflow in the Lungs When Delivered Using an eFlow Nebulizer in Patients With Chronic Obstructive Pulmonary Disease (COPD) | July 2010 | November 2010 |
| NCT01514266 | Completed | N/A | Effect of Curcumin on Lung Inflammation | April 2005 | August 2010 |
| NCT03264924 | Completed | Improving Physical Activity in Rehabilitation | July 24, 2017 | January 30, 2020 | |
| NCT01644162 | Completed | N/A | Ventilator Monitoring in Early Exacerbation Detection | July 2012 | January 2014 |
| NCT03754881 | Completed | Efficacy of 8-week Supervision in Home Based Pulmonary Rehabilitation | September 1, 2018 | September 6, 2020 | |
| NCT05611125 | Completed | N/A | Nursing-Driven Primary Palliative Care for Urban-Dwelling African Americans With Chronic Lung Disease | December 2, 2022 | November 30, 2023 |
| NCT00891462 | Completed | Phase 3 | Efficacy and Safety of Aclidinium Bromide for Treatment of Moderate to Severe Chronic Obstructive Pulmonary Disease (COPD) (LAS-MD-33) | April 2009 | November 2009 |
| NCT03425760 | Completed | A Cross-sectional Study of COPD and Symptom Variability in MEA Countries | December 7, 2015 | March 31, 2017 | |
| NCT01475045 | Completed | ANASA (Patients' Satisfaction With Pulmonary Diseases' Treatment) | January 2011 | September 2011 | |
| NCT01168310 | Completed | Phase 2 | A Trial to Assess the Pharmacodynamic Response in Subjects With Chronic Obstructive Pulmonary Disease (COPD) | August 2010 | October 2011 |
| NCT04739774 | Completed | Phase 1 | Investigation of the Effect of Inhibition of CYP3A4/5 by Itraconazole on the PK of CHF6001 (Tanimilast) | February 22, 2021 | April 26, 2021 |
| NCT02148289 | Completed | N/A | Dietary Nitrate in COPD | November 2012 | March 2013 |
| NCT02674880 | Completed | Phase 2 | Hyaluronic Acid in Acute Exacerbation of COPD - Duration Of Noninvasive Assistance | March 2016 | September 2019 |
| NCT00666367 | Completed | Phase 4 | Vitamin D as Treatment for Chronic Obstructive Pulmonary Disease (COPD) | January 2008 | August 2010 |
| NCT01942889 | Completed | N/A | Antioxidants and Pulmonary Rehabilitation in COPD Patients | April 2012 | December 2014 |
| NCT01709864 | Completed | Phase 3 | NVA237 Versus Placebo 12-week Efficacy Study | November 2012 | October 2013 |
| NCT03540901 | Completed | Phase 4 | Effect of Acetazolamide on Lung Water Content by Ultrasound in Patients With Respiratory Disease at Altitude | May 22, 2018 | August 2, 2018 |
| NCT01072448 | Completed | Phase 3 | 12-week Efficacy of Indacaterol | January 2010 | July 2010 |
| NCT00501852 | Completed | Phase 2 | Efficacy and Safety of Four Doses of Glycopyrronium Bromide (NVA237) in Patients With Stable Chronic Obstructive Pulmonary Disease (COPD), in Comparison to an Active Comparator Tiotropium | July 2007 | |
| NCT01044927 | Completed | Phase 3 | Advanced eHealth for Chronic Obstructive Pulmonary Disease (COPD) in Colorado | September 2006 | June 2008 |
| NCT05083429 | Completed | Replication of the POET-COPD Trial in Healthcare Claims Data | September 22, 2020 | August 9, 2021 | |
| NCT02136875 | Completed | Phase 4 | Strategy for Early Treatment of Exacerbations in COPD: Standing Prescriptions of Advair With a Written Action Plan in the Event of an Exacerbation | July 2008 | August 2010 |
| NCT01108991 | Completed | N/A | Randomized Trial of Physical Activity Self-Management Intervention for Patients With COPD | April 2010 | April 2014 |
| NCT01949181 | Completed | N/A | Blood, Hair and Lung Concentrations of Metals and Metalloids in Patients With Lung Cancer or Chronic Obstructive Pulmonary Disease | August 2011 | March 2014 |
| NCT01768754 | Completed | Walking Speeds in Patients With Chronic Obstructive Pulmonary Disease | July 2012 | March 2013 | |
| NCT00889447 | Completed | Screening Evaluation for Studies of Chronic Obstructive Pulmonary Disease (COPD) | January 2008 | May 2017 | |
| NCT01149772 | Completed | N/A | Adjusting to Chronic Conditions Using Education, Support, and Skills | February 2011 | October 2014 |
| NCT00448500 | Completed | Exhaled Breath Condensate (EBC) Assessment in Acute Exacerbation of Chronic Obstructive Pulmonary Disease (COPD) | February 2006 | January 2008 | |
| NCT03516994 | Completed | N/A | Reducing Disparities in the Quality of Advance Care Planning for Older Adults | August 1, 2018 | April 15, 2024 |
| NCT00999908 | Completed | Phase 3 | Comparison of the Effects of Indacaterol and Tiotropium on Inspiratory Capacity | October 2009 | March 2010 |
| NCT02877524 | Completed | N/A | Trial to Study Intubation Rates of Non-invasive Ventilation Using Pressure Support Ventilation (PSV) Versus Adaptive Support Ventilation (ASV) Mode in Patients With Acute Exacerbation of Chronic Obstructive Pulmonary Disease | September 1, 2016 | December 31, 2017 |
| NCT01679782 | Completed | Involvement of Nervous System in Muscle Weakness in COPD Patients | July 2012 | April 2014 | |
| NCT01522729 | Completed | N/A | Impact of Muscle Afferent Feedback During Exercise in Patients With Chronic Obstructive Pulmonary Disease (COPD) | October 2010 | January 2012 |
| NCT00156780 | Completed | Phase 1 | Phase 1 Safety and Pharmacokinetic Study of AI-700 in Patients With Diminished DLCO and COPD and/or CHF | August 2004 | July 2005 |
| NCT03311373 | Completed | Phase 1 | A Randomized, Open-label, Single-dose, Single-center, Crossover Study in Healthy Subjects to Assess the Relative Bioavailability of PT010 | October 17, 2017 | December 15, 2017 |
| NCT04360226 | Completed | Assessing the Utility of Peak Inspiratory Flow as a Predictor for COPD Exacerbations | December 14, 2020 | January 25, 2024 | |
| NCT00515164 | Completed | Phase 2 | US Biologic Lung Volume Reduction (BLVR) Phase 2 Emphysema Study | August 2007 | December 2009 |
| NCT01050465 | Completed | N/A | MedlinePlus Health Prescriptions: Developing a Pragmatic Approach for Clinic Use | May 2009 | December 2010 |
| NCT01145300 | Completed | Biomarkers in Chronic Obstructive Pulmonary Disease (COPD) | June 2010 | May 2011 | |
| NCT04953611 | Completed | Quantitative Study on HRCT Phenotype of COPD | July 1, 2013 | November 30, 2014 | |
| NCT01658020 | Completed | Phase 3 | A Study to Evaluate Efficacy and Safety Profile of Zabofloxacin Tablet 400mg and Moxifloxacin Tablet 400mg | August 2012 | August 2014 |
| NCT00495586 | Completed | Phase 4 | Effectiveness of Antibiotic Therapy for Exacerbations of Chronic Obstructive Pulmonary Disease | October 2007 | July 2011 |
| NCT05922254 | Completed | N/A | Combined Effects of ACBT and AUTOGENIC DRAINAGE in Patients With Chronic Obstructive Pulmonary Disease | June 15, 2023 | December 5, 2023 |
| NCT01333904 | Completed | Phase 1 | Safety, Tolerability, and Pharmacodynamic Effect Study of PUR118 | February 2011 | June 2012 |
| NCT00245661 | Completed | Phase 3 | Effects of Temazepam in Patients With Chronic Pulmonary Obstructive Disease | October 2005 | August 2007 |
| NCT00000621 | Completed | Phase 2 | Feasibility of Retinoic Acid Treatment in Emphysema (FORTE) | September 1999 | December 2004 |
| NCT04711057 | Completed | N/A | CENTR(AR): Lungs Moving | April 1, 2021 | December 31, 2023 |
| NCT00202189 | Completed | Phase 4 | Effects of Inhaled Corticosteroids in Chronic Obstructive Pulmonary Disease (COPD) | September 2005 | November 2005 |
| NCT00517998 | Completed | Phase 1 | Israeli Biologic Lung Volume Reduction (BLVR) Phase 1 Emphysema Study | May 2007 | March 2009 |
| NCT02035293 | Completed | N/A | Frequency of Diagnostic Symptomatic Pulmonary Embolism's in Patients Hospitalized for Clinical Exacerbation of Chronic Obstructive Pulmonary Disease (COPD) | January 8, 2014 | October 13, 2017 |
| NCT01150383 | Completed | Phase 4 | SCOPE-Study: Salzburg Chronic Obstructive Pulmonary Disease- Exercise and Oxygen Study | July 2010 | July 2013 |
| NCT00970268 | Completed | Phase 3 | Long-term Extension Study of the Safety, Tolerability, and Efficacy of Aclidinium Bromide in Patients With Moderate to Severe Chronic Obstructive Pulmonary Disease (COPD) (LAS-MD-36) | August 2009 | October 2010 |
| NCT02445079 | Completed | Ugandan Non-Communicable Diseases and Aging Cohort | December 2013 | May 2018 | |
| NCT02557958 | Completed | Early Phase 1 | Chronic Obstructive Pulmonary Disease Transcription Factor and Cytokine Study | January 2009 | December 2018 |
| NCT01225627 | Completed | N/A | Discharge Coordinator Intervention in Patients With Chronic Obstructive Pulmonary Disease (COPD) | November 2009 | June 2012 |
| NCT03196089 | Completed | Phase 2 | Effect of Short-term Oxygen During CPET in COPD | June 2, 2017 | December 31, 2018 |
| NCT00259779 | Completed | Phase 3 | Comparison Between Symbicort® and Prednisolone in COPD | September 2005 | July 2007 |
| NCT00287625 | Completed | N/A | Early Pulmonary Rehabilitation for Hospitalized Patients With Exacerbations of Chronic Obstructive Pulmonary Disease (COPD) | January 2006 | June 2011 |
| NCT03250182 | Completed | Phase 1 | A Study to Assess the PK and Safety of PT010 in Subjects With COPD Following Single and Repeat Dose | August 11, 2017 | December 7, 2017 |
| NCT01070784 | Completed | Phase 3 | A Safety and Efficacy Study of Symbicort Turbuhaler Compared With Standard Chronic Obstructive Pulmonary Disease (COPD) Treatment in Japan | January 2010 | October 2011 |
| NCT01580423 | Completed | N/A | The Role of Substance P on Perception of Breathlessness During Resistive Load Breathing | April 2012 | March 2013 |
| NCT02252588 | Completed | Phase 2 | The Effect of Chlorhexidine on the Oral and Lung Microbiota in Chronic Obstructive Pulmonary Disease | September 1, 2014 | January 1, 2020 |
| NCT00000606 | Completed | Phase 3 | National Emphysema Treatment Trial (NETT) | December 1996 | December 2005 |
| NCT03179826 | Completed | Analysis of Inhaled Corticoid Prescriptions in General Medicine | July 13, 2017 | December 31, 2018 | |
| NCT02300064 | Completed | N/A | Exercise in Health and Chronic Obstructive Pulmonary Disease | January 2009 | May 2016 |
| NCT00064402 | Completed | Phase 3 | Determine the Safety and Efficacy of (R,R)-Formoterol in the Treatment of Subjects With COPD | April 2002 | March 2004 |
| NCT04417842 | Completed | Connect Lung Outcomes With Bronchodilator Use | August 27, 2020 | April 25, 2022 | |
| NCT00634413 | Completed | Phase 2 | Effect of ADC4022 Co-Administered With Budesonide on Pulmonary Inflammation in Subjects With Moderate to Severe COPD | February 2008 | January 2009 |
| NCT01801722 | Completed | Using NT-proBNP to Detect Chronic Heart Failure in Patients With Chronic Obstructive Pulmonary Disease | April 2008 | June 2008 | |
| NCT00831220 | Completed | Endothelial Dysfunction in Chronic Obstructive Pulmonary Disease | March 2005 | October 2007 | |
| NCT00657293 | Completed | N/A | Arm Training in Patients With Chronic Obstructive Pulmonary Disease | July 2008 | January 2010 |
| NCT01613326 | Completed | Phase 3 | Efficacy, Safety, and Tolerability of NVA237 Compared to Tiotropium in Patients With Chronic Obstructive Pulmonary Disease (COPD) | June 2012 | January 2013 |
| NCT00186706 | Completed | Phase 4 | Selenium Supplementation in Chronic Obstructive Pulmonary Disease (COPD) Patients | September 2005 | November 2007 |
| NCT03152994 | Completed | The Early Predictors for Developing Type 2 Diabetes Mellitus in Patients With Chronic Obstructive Pulmonary Disease | April 1, 2017 | May 1, 2020 | |
| NCT01513616 | Completed | N/A | The Impact of Pulmonary Rehabilitation on Dyspnea in Chronic Obstructive Pulmonary Disease | November 2006 | December 2011 |
| NCT00782535 | Completed | Phase 2 | Safety and Efficacy Study of Treatment With Single Doses of CHF 4226 pMDI in Patients With Chronic Obstructive Pulmonary Disease (COPD) | December 2008 | March 2009 |
| NCT02634983 | Completed | Phase 4 | QVA Mechanistic Efficacy Study (Receptor Effects, Etc) | June 3, 2016 | September 26, 2017 |
| NCT06389734 | Completed | N/A | Combining Manual Soft Tissue Release and Exercise Training in COPD: the Effect on LF, EC, and CAF | March 2, 2023 | February 2, 2024 |
| NCT03017300 | Completed | N/A | Transdiaphragmatic Pressure and Neural Respiratory Drive Measured During Inspiratory Muscle Training in COPD | January 2016 | December 2016 |
| NCT02133339 | Completed | Phase 1 | Single Ascending Dose Study of TRN-157 in Healthy Subjects | May 2014 | September 2014 |
| NCT04536402 | Completed | Evaluate the Safety Profile of BGF MDI in Chinese Patients With COPD in Routine Clinical Practice | March 16, 2021 | November 8, 2023 | |
| NCT03085485 | Completed | Phase 2 | The Topic Trial - Study to Determine the Safety and Efficacy of Ivacaftor | March 16, 2017 | September 30, 2022 |
| NCT02343458 | Completed | Phase 3 | Study to Assess the Efficacy and Safety of PT003, PT005, and PT001 in Subjects With Moderate to Very Severe COPD | March 30, 2015 | August 31, 2017 |
| NCT02128529 | Completed | Epidemiology of Chronic Bronchitis in Patients With Chronic Obstructive Pulmonary Disease (COPD) | October 2010 | April 2011 | |
| NCT00807534 | Completed | N/A | Sensitivity of New Exercise Tests in Chronic Obstructive Pulmonary Disease (COPD) | October 2008 | June 2010 |
| NCT06114238 | Completed | Phase 1 | Pharmacokinetic Study to Compare Itepekimab Exposure When Administered With an Autoinjector Versus Prefilled Syringe | September 16, 2021 | March 8, 2022 |
| NCT00939211 | Completed | Phase 2 | The Study Will Evaluate the Effect of AZD9164 in Patients With Chronic Obstructive Pulmonary Disease | June 2009 | November 2009 |
| NCT01337661 | Completed | A Study of the Inflammatory Pathways Associated With Chronic Obstructive Pulmonary Disease Exacerbations | April 2011 | February 2012 | |
| NCT01335672 | Completed | Survival After First Myocardial Infarction in Patients With and Without Chronic Obstructive Pulmonary Disease | March 2011 | December 2014 | |
| NCT00311961 | Completed | Phase 4 | Intravenous Versus Oral Administration of Prednisolone in Exacerbations of Chronic Obstructive Pulmonary Disease (COPD) | June 2001 | August 2003 |
| NCT03532243 | Completed | N/A | Acute Effects of Incremental Inspiratory Loads on Respiratory Mechanics and NRD in Patient With Stable COPD. | April 1, 2018 | February 1, 2019 |
| NCT03167034 | Completed | Phase 4 | Effect of Acetazolamide on Right Ventricular Function During Exercise in Patients With Respiratory Disease at Altitude | May 24, 2017 | August 2, 2018 |
| NCT01545011 | Completed | N/A | Effects of Inspiratory Muscle Training on Dyspnea in Subjects With Chronic Obstructive Pulmonary Disease | October 2011 | September 2012 |
| NCT01135381 | Completed | N/A | IVR-Enhanced Care Transition Support for Complex Patients | February 2010 | March 2012 |
| NCT00139516 | Completed | N/A | Chinese Community Smoking Cessation Project | September 2001 | August 2007 |
| NCT03256552 | Completed | Phase 2 | Study to Assess the Efficacy and Safety of Three Doses of PT001 in Japanese Subjects With Moderate to Severe COPD | January 28, 2015 | September 5, 2015 |
| NCT03955770 | Completed | Phase 4 | Effects of HFOT on Exercise Performance in Patients With COPD. A Randomized, Controlled Trial. | May 20, 2019 | August 2, 2019 |
| NCT01090999 | Completed | N/A | Long - Term Respiratory Rehabilitation Programs in Chronic Obstructive Pulmonary Disease. | October 2006 | December 2012 |
| NCT02487446 | Completed | Phase 3 | Efficacy and Safety Study of QVA149 in COPD Patients | July 28, 2015 | September 12, 2016 |
| NCT01380639 | Completed | N/A | Effects of Vibration Training on Exercise Capacity in COPD-patients | September 2010 | April 2011 |
| NCT02278523 | Completed | Phase 2/Phase 3 | The Respiratory Physiology Variation of COPD Patients in Inspiratory Muscle Training | June 2014 | October 2014 |
| NCT00462540 | Completed | Phase 3 | A Crossover Study in the Treatment of Patients With COPD | May 2007 | October 2007 |
| NCT02978703 | Completed | EvAluation of Clinical Effectiveness Of RoLenium Administered With Elpenhaler in Chronic Obstructive Pulmonary Disease (COPD) patientS in Daily Clinical Practice, in Greece | January 2017 | December 2018 | |
| NCT02288039 | Completed | N/A | Quality of Life in Pulmonary Rehabilitation: A Social Identity Based Intervention | March 2015 | September 2016 |
| NCT01619098 | Completed | N/A | Evaluating Sequential Strategies to Reduce Readmission in a Diverse Population | October 2011 | November 2013 |
| NCT01366469 | Completed | Inflammatory Biomarkers Predict Pulmonary Outcomes in Coronary Artery Bypass Grafting | April 2011 | December 2013 | |
| NCT00452764 | Completed | Regulatory T Cells in COPD | January 2007 | November 2007 | |
| NCT04448626 | Completed | Micro-environment Involvement in Muscle Alteration Induced | March 1, 2020 | May 30, 2020 | |
| NCT02882165 | Completed | N/A | Clinical And Social Characteristics and Demographics in COPD | July 2015 | February 2017 |
| NCT00102401 | Completed | N/A | Internet-Based and Established Dyspnea Self-Management Programs in Chronic Obstructive Pulmonary Disease (COPD) Patients | September 2003 | June 2007 |
| NCT02202616 | Completed | Phase 4 | Prospective Cohort Study for the Real - Life Effectiveness Evaluation of GlycOpyrronium With IndacatERol Combination in the Management of COPD in Canada (POWER Study) | August 27, 2014 | April 5, 2017 |
| NCT05758428 | Completed | Phase 1 | A Study to Evaluate the Pharmacokinetics, Safety and Tolerability of Nebulized Ensifentrine in Healthy Chinese Subjects | March 6, 2023 | April 18, 2023 |
| NCT01361451 | Completed | Myotrace: An Evaluation of a Novel Critical Illness Monitoring System | January 2011 | January 2014 | |
| NCT01715337 | Completed | N/A | Effects of Rehabilitation on Muscle Fibre Composition and Capillaries in Chronic Obstructive Pulmonary Disease (COPD) Patients | February 2010 | April 2014 |
| NCT00739648 | Completed | Phase 2 | A Phase 2 Study of MP-376 to Prevent Acute Exacerbations in Chronic Obstructive Pulmonary Disease (COPD) Patients | October 2008 | April 2010 |
| NCT01941225 | Completed | Phase 2 | Inhaled Iloprost, Dynamic Hyperinflation, and Oxidative Stress in COPD Patients | September 2013 | November 2016 |
| NCT03237962 | Completed | N/A | High Flow Nasal Cannula During Pulmonary Rehabilitation | August 2016 | August 2018 |
| NCT02024737 | Completed | SILO2 (Signal Intensity Lung washOut) | February 2014 | September 2015 | |
| NCT01455129 | Completed | Phase 4 | Tiotropium In Early Chronic Obstructive Pulmonary Disease Patients in China | November 2011 | August 2016 |
| NCT01294033 | Completed | N/A | Effect of Supplemental Oxygen on Maximal Oxygen Consumption in Patients With Chronic Obstructive Pulmonary Disease | August 2009 | July 2010 |
| NCT01204970 | Completed | Confocal Laser Micro-endoscopy in Chronic Obstructive Pulmonary Disease (COPD) and Lung Transplant Recipients | September 2010 | December 2016 | |
| NCT04761380 | Completed | Decreased Tongue Strength is Related to Skeletal Muscle Mass in COPD Subjects | December 1, 2019 | May 10, 2020 | |
| NCT01529632 | Completed | Phase 3 | Comparison of Safety and Efficacy of the Combination Product QVA149A Against the Concurrent Administration of the Individual Components, QAB149 and NVA237, in Patients With Chronic Obstructive Pulmonary Disease (COPD) | May 2012 | December 2012 |
| NCT00887705 | Completed | N/A | ADL- Training for Patients With Chronic Obstructive Pulmonary Disease (COPD) | May 2009 | June 2010 |
| NCT04069052 | Completed | Early Phase 1 | The Effect of Inhaled Nitric Oxide on Deadspace in COPD | September 1, 2021 | May 30, 2023 |
| NCT00477074 | Completed | Pulmonary and Systemic Hepatocyte Growth Factors in Patients With COPD | January 2004 | December 2005 | |
| NCT03004352 | Completed | N/A | Disturbed Blood Flow Induces Endothelial Dysfunction in Severe Chronic Obstructive Pulmonary Disease | April 2015 | May 2015 |
| NCT01044459 | Completed | Phase 3 | Long-term Safety, Tolerability and Efficacy of Aclidinium Bromide in Patients With Moderate to Severe Chronic Obstructive Pulmonary Disease (COPD) (LAS-MD-35) | November 2009 | April 2011 |
| NCT00972140 | Completed | Phase 3 | Formoterol-HFA 3-month Study in Chronic Obstructive Pulmonary Disease (COPD) Patients | August 2005 | October 2006 |
| NCT01305668 | Completed | Rehabilitation in Chronic Obstructive Pulmonary Disease (COPD) Patients With Emphysema | August 2011 | December 2012 | |
| NCT03564028 | Completed | N/A | Energy Conservation Technique in COPD Patients | July 23, 2018 | March 29, 2019 |
| NCT02875522 | Completed | N/A | The Effects of Aerobic Exercise Training on Vascular, Cardiac and Cerebral Vascular Function in COPD | January 2012 | May 2015 |
| NCT04202991 | Completed | The Relationship Between Pain, Balance and Gait in People With Chronic Obstructive Pulmonary Disease | May 1, 2019 | December 18, 2019 | |
| NCT05601180 | Completed | N/A | Evaluation of the Efficacy of Respicure® (Resveratrol / Quercetin) in the Management of Respiratory Conditions Including Asthma,COPD and Long COVID. | October 27, 2022 | January 15, 2024 |
| NCT01772342 | Completed | N/A | Effects of an Air Purifying Device (PureNight) on Sleep Quality in Obstructive Lung Disease | March 2009 | November 2011 |
| NCT01530412 | Completed | N/A | Long Term Evaluation of Activity Levels Post Pulmonary Rehabilitation | June 2007 | July 2010 |
| NCT00784342 | Completed | Validation of PROMIS Banks With COPD Exacerbations | July 2008 | June 2009 | |
| NCT04080570 | Completed | N/A | Remote Physician Care for Home Hospital Patients | August 3, 2019 | April 27, 2020 |
| NCT05651958 | Completed | N/A | Effects of Pranayama Breathing Technique in Patients With Chronic Obstructive Pulmonary Disease | February 1, 2022 | January 31, 2023 |
| NCT04123730 | Completed | N/A | Automated Oxygen Titration During Walking in Patients With COPD | October 28, 2019 | December 1, 2020 |
| NCT01331070 | Completed | N/A | Identification and Dynamics With Cerebral Functional Magnetic Resonance Imaging | March 2011 | March 2013 |
| NCT02652559 | Completed | N/A | Initiation of Long-term Non-invasive Ventilation in COPD | June 2016 | July 25, 2018 |
| NCT01120717 | Completed | Phase 3 | A Study to Assess the Long-term Safety of QVA149 | April 2010 | December 2011 |
| NCT01713335 | Completed | Proteasis Evaluation in COPD | October 18, 2012 | April 2017 | |
| NCT02261727 | Completed | Phase 4 | Theophylline and Steroids in Chronic Obstructive Pulmonary Disease (COPD) Study | June 2014 | May 14, 2018 |
| NCT00489853 | Completed | Phase 4 | Evaluation of Efficacy on Exercise Tolerance of Symbicort (Budesonide/Formoterol) Compared to Placebo and Oxis in Patients With Severe COPD | July 2007 | August 2008 |
| NCT04515758 | Completed | N/A | Determining the Feasibility of Implementing a Combined Cognitive and Exercise Training Program for Older Adults in a Community Setting. | April 1, 2019 | April 24, 2020 |
| NCT02796599 | Completed | N/A | Interfaces of Non-invasive Ventilation on Performance in Patients With Chronic Obstructive Pulmonary Disease | June 2016 | February 2018 |
| NCT01582958 | Completed | N/A | The Effect of OMT on Patients With COPD: Correlating Pulmonary Function Tests With Biochemical Alterations | April 2013 | August 2015 |
| NCT00886639 | Completed | N/A | Effect of Oxygen-supply on 6-Minute-Walking-Distance of COPD III/IV-patients | December 2008 | August 2009 |
| NCT00056264 | Completed | Phase 3 | A Study of Safety and Efficacy of Infliximab (Remicade) in Patients With COPD | December 2002 | December 2004 |
| NCT03443479 | Completed | Comparison of High-flow Oxygen vs. BiPAP in Type II (Hypercapnic) Respiratory Failure | April 1, 2015 | July 1, 2019 | |
| NCT02015767 | Completed | Patient Registry of Roflumilast In Real Life | February 1, 2013 | August 31, 2016 | |
| NCT01587079 | Completed | Phase 2 | Glycopyrrolate/Formoterol Fumarate MDI Compared With Spiriva® as An Active Control in Patients With Moderate to Severe Chronic Obstructive Pulmonary Disease | April 2012 | October 2012 |
| NCT05061810 | Completed | N/A | The Effect of a Smartphone Application Self-management Programme on Clinical Health Outcomes in Patients With Chronic Obstructive Pulmonary Disease. | September 13, 2021 | February 28, 2023 |
| NCT02631434 | Completed | N/A | Comparison Between Sit-to-stand Test and Six-minute Walk Test in Chronic Obstructive Pulmonary Disease | August 2013 | August 2013 |
| NCT03819517 | Completed | Early Phase 1 | Improving Cardiovascular Health in Patients With Chronic Obstructive Pulmonary Disease | July 1, 2019 | August 30, 2023 |
| NCT00929110 | Completed | Phase 3 | 1-year Study to Assess the Efficacy, Safety, and Tolerability of Glycopyrronium Bromide (NVA237) in Chronic Obstructive Pulmonary Disease (COPD) | June 2009 | April 2011 |
| NCT01273298 | Completed | N/A | Effects of Cardioselective β-blockers on Dynamic Hyperinflation in COPD | June 2008 | October 2010 |
| NCT00005285 | Completed | Effect of Maternal Smoking On Neonatal Lung Function | July 1985 | November 1996 | |
| NCT02076061 | Completed | Biomarkers of Early Chronic Obstructive Pulmonary Disease (COPD) in Smokers - Longitudinal Study | February 2014 | April 30, 2020 | |
| NCT02860728 | Completed | N/A | Resistance Training to Prehabilitate Patients With Chronic Obstructive Pulmonary Disease | August 2016 | February 2020 |
| NCT01270594 | Completed | Phase 2 | A Pilot Study to Evaluate a Telepharmacy Intervention to Improve Inhaler Adherence in Veterans With COPD | January 2011 | April 2012 |
| NCT02135432 | Completed | Early Phase 1 | TOPIC Trial for COPD | May 2015 | November 2015 |
| NCT00605540 | Completed | Chronic Obstructive Pulmonary Disease Markers and Prognosis | January 2008 | February 2012 | |
| NCT00975403 | Completed | N/A | Pathophysiological Mechanisms of Dyspnea and Activity-limitation in Mild Chronic Obstructive Pulmonary Disease (COPD) | October 2010 | September 2012 |
| NCT05001009 | Enrolling by invitation | N/A | Goals of Care Conversations Study | September 13, 2022 | September 30, 2025 |
| NCT01460264 | Enrolling by invitation | An Open Prospective Longitudinal Pulmonary-cardiovascular Cohort Study | October 16, 2013 | December 2026 | |
| NCT06201104 | Enrolling by invitation | N/A | Patient Empowerment Training for COPD Patients | January 1, 2024 | December 31, 2024 |
| NCT05632120 | Enrolling by invitation | Investigation of Impairments in Body Functions and Structures, Activities and Participation Restrictions in COPD | December 5, 2022 | September 30, 2024 | |
| NCT04089111 | Not yet recruiting | N/A | Closed Loop Ventilation With High Tidal Volumes and Safe Transpulmonary Pressure in COPD (COPD-SAFE) | June 2023 | March 2024 |
| NCT06456996 | Not yet recruiting | N/A | Impact of Multi-Component Interventions on High Risk COPD Population | June 17, 2024 | October 1, 2025 |
| NCT04983485 | Not yet recruiting | Respiratory Muscle Activations During Stable Threshold Load and Increasing Threshold Load Endurance Tests in COPD | June 25, 2023 | August 25, 2023 | |
| NCT05681364 | Not yet recruiting | Prediction of Pulmonary Rehabilitation Outcomes in Patients With Chronic Respiratory Disease Based on Metabolomics: a Prospective Cohort Study | April 2023 | December 2024 | |
| NCT03647462 | Not yet recruiting | N/A | Impact of Early Diagnosis and Treatment of OSA on Hospital Readmission in Hospitalized COPD Patients | June 2023 | April 2025 |
| NCT06326957 | Not yet recruiting | N/A | Reducing Chronic Breathlessness in Adults by Following a Self-guided, Internet Based Supportive Intervention (SELF-BREATHE) | May 2024 | July 2028 |
| NCT04974788 | Not yet recruiting | N/A | Examination of Acute Effects of Different Intensity Respiratory Muscle Training on Respiratory Muscle Activations | June 30, 2023 | August 30, 2023 |
| NCT06349174 | Not yet recruiting | N/A | Safety and Efficacy of Endobronchial Valve for Bronchoscopic Lung Volume Reduction Surgery: A Prospective Pilot Study | April 11, 2024 | March 31, 2025 |
| NCT05104593 | Not yet recruiting | N/A | An Integrated Solution for Sustainable Care for Multimorbid Elderly Patients With Dementia | January 1, 2024 | December 31, 2025 |
| NCT06346678 | Not yet recruiting | Accuracy of Accuhaler Tester, Ellipta Tester and Turbutester in Patients With Chronic Obstructive Pulmonary Disease | April 16, 2024 | October 31, 2024 | |
| NCT06275230 | Not yet recruiting | Establishment of Human Lung Stem Cell Proliferation System and Organoid Construction in COPD | March 20, 2024 | December 31, 2025 | |
| NCT06334575 | Not yet recruiting | Phase 4 | Molecular Signatures Associated With Response to ICS Treatment in Patients With COPD Stratified by Eosinophil Levels | July 2024 | December 2025 |
| NCT05586399 | Not yet recruiting | N/A | The Effect of Maximal Strength Training on Lung Function in Patients With COPD | November 15, 2022 | June 30, 2024 |
| NCT06439875 | Not yet recruiting | N/A | Effects of L-arginine and Liposomial Vitamin C on Severe Copd Patients Undergoing Pulmonary Rehabilitation. | July 1, 2024 | July 1, 2025 |
| NCT05937854 | Not yet recruiting | Phase 2 | Breathe Easier With Tadalafil Therapy for Dyspnea in COPD-PH | April 1, 2024 | December 1, 2027 |
| NCT05793697 | Not yet recruiting | Assessment Of Different Scores In Predicting Outcome In AECOPD Patients In Emergency Department | May 3, 2023 | December 3, 2024 | |
| NCT06314035 | Not yet recruiting | N/A | Decision Support on End-of-life Care Planning in Older Adults | March 10, 2024 | January 31, 2025 |
| NCT06234345 | Not yet recruiting | Phase 3 | Study of Fluticasone/Formoterol/Glycopyrronium for the Treatment Chronic Obstructive Pulmonary Disease (TRIPLAR) | February 28, 2026 | July 30, 2028 |
| NCT05871671 | Not yet recruiting | N/A | The Effects of Pulmonary Rehabilitation on Bone Mineral Density in Patients Diagnosed With Chronic Obstructive Pulmonary Disease | May 2023 | September 2025 |
| NCT06246370 | Not yet recruiting | An Investigation of the Cervical Region Biomechanics in Patients With Chronic Obstructive Pulmonary Disease | February 20, 2024 | September 6, 2025 | |
| NCT06390345 | Not yet recruiting | N/A | Functional Improvement in OSA and COPD With a Telehealth LifeStyle and Exercise Intervention | May 1, 2024 | October 1, 2028 |
| NCT05814484 | Not yet recruiting | Role of Inhaler Adherence and Blood Eosinophil Count in Exacerbations of COPD | August 10, 2023 | January 2025 | |
| NCT05774730 | Not yet recruiting | Evaluation of the Effectiveness of Predicting the Integrity of Interlobar Fissures Based on Chest Image AI Technology | March 26, 2023 | December 31, 2024 | |
| NCT06108973 | Not yet recruiting | Evaluation of Consumption of Sevoflurane in Chronic Obstructive Pulmonary Disease Patients | January 1, 2024 | March 30, 2025 | |
| NCT05986214 | Not yet recruiting | N/A | Developing an Intervention to Optimize Virtual Care Adoption for COPD Management | March 1, 2026 | August 31, 2028 |
| NCT06026709 | Not yet recruiting | N/A | Effectiveness and Cost-effectiveness of Digital Psychological Intervention (EmoEase) in Chinese COPD Patients | June 1, 2024 | January 30, 2025 |
| NCT06399094 | Not yet recruiting | Frequency-time Analysis of Pathological Lung Sounds: Detection and Quantification of Pathological Sounds in Patients With Cystic Fibrosis, Pulmonary Fibrosis or COPD (Chronic Obstructive Pulmonary Disease) | June 1, 2024 | January 1, 2025 | |
| NCT06287476 | Not yet recruiting | N/A | Alveolar-capillary Reserve After Exercise in Chronic Obstructive Pulmonary Disease (COPD) (COP-DTPA) | March 15, 2024 | March 15, 2025 |
| NCT06408285 | Not yet recruiting | Phase 1 | A Study of TQC3927 Powder for Inhalation in Healthy Adult Subjects | May 2024 | February 2025 |
| NCT05967091 | Not yet recruiting | N/A | Ryme Medical TLD Pilot Study | September 2023 | December 2025 |
| NCT06085261 | Not yet recruiting | N/A | COPD: A Multi-center Supervised Tele-rehabilitation Study | November 2023 | December 2024 |
| NCT06259188 | Not yet recruiting | N/A | Effectiveness of Personalized Breathing Exercise Device in Patients With COPD | April 10, 2024 | May 29, 2025 |
| NCT05025774 | Not yet recruiting | Fitness and Lung Function Among Survivors of Heart Transplant, Leukemia and Infant BPD Through Exercise | September 1, 2024 | August 1, 2025 | |
| NCT06101459 | Not yet recruiting | A Study About Association Between Microbiome, Metabolome and Clinical Characteristics in COPD Patients | December 1, 2023 | December 31, 2028 | |
| NCT05975788 | Not yet recruiting | Phase 4 | Effect of Staphylococcus and Neisseria Tablets on Clinical Outcome Among Patients With Chronic Obstructive Pulmonary Disease | November 2023 | July 2025 |
| NCT05934565 | Not yet recruiting | N/A | Mindful Steps 2.0: Promoting Physical Activity in Patients With COPD and HF | June 30, 2024 | June 30, 2028 |
| NCT06028711 | Not yet recruiting | N/A | Education Impact on Rehabilitation of Hospitalized Patients With Chronic Obstructive Pulmonary Disease. | September 2023 | December 2024 |
| NCT05587829 | Not yet recruiting | N/A | Effects of Diaphragm and Abdominal Muscle Training on PFT and Dyspnea Among COPD Obstructive Pulmonary Disease Patients. | October 2022 | January 1, 2023 |
| NCT06377410 | Not yet recruiting | N/A | Efficacy & Safety of Dry Powder Ivy Extract (Syrup Prospan) Versus NAC Among COPD Patients | May 1, 2024 | November 30, 2026 |
| NCT06326658 | Not yet recruiting | N/A | Bufei Yishen Prescription on Patients With Frequent AECOPD in Stable Stage | April 1, 2024 | October 31, 2026 |
| NCT06313372 | Not yet recruiting | Interpreting Respiratory Oscillometry in Adult Asthma and COPD: a Delphi Study | March 2024 | January 2025 | |
| NCT05815420 | Not yet recruiting | Home Tele-Monitoring of Non-Invasive Ventilation in COPD Patients in France | September 1, 2023 | December 30, 2025 | |
| NCT05805332 | Not yet recruiting | Evaluation of Skeletal Muscle Function Using Ultrasonic Elastography | April 7, 2023 | December 31, 2024 | |
| NCT05130294 | Not yet recruiting | N/A | Unrefined Salmon Oil as Dietary Supplement in Patient With Chronic Obstructive Pulmonary Disease | July 2024 | November 2025 |
| NCT06174207 | Not yet recruiting | N/A | Hyperoxia During Pulmonary Rehabilitation in Chronic Lung Disease - Does it Matter? | January 1, 2024 | April 30, 2025 |
| NCT06456749 | Not yet recruiting | Xishui Project for IDM of COPD and Comorbidities | June 17, 2024 | March 15, 2026 | |
| NCT05997550 | Not yet recruiting | N/A | The Effect of Pursed Lip Breathing Exercise and Laughter Therapy Individuals With The COPD | February 15, 2024 | March 15, 2025 |
| NCT04231760 | Not yet recruiting | Phase 1/Phase 2 | The Effect of Inhaled Nitric Oxide on Pulmonary Gas-exchange in COPD | December 1, 2024 | February 1, 2026 |
| NCT03622528 | Not yet recruiting | Quantitative Lung Cancer Screening | July 2024 | October 2024 | |
| NCT05835492 | Recruiting | A Pragmatic Real-world Multicentre Observational Research Study to Explore the Clinical and Health Economic Impact of myCOPD | September 4, 2023 | October 1, 2024 | |
| NCT06308289 | Recruiting | N/A | Combined Effects of Global Posture Re-education and Active Cycle of Breathing Technique in COPD | March 3, 2024 | June 15, 2024 |
| NCT04004689 | Recruiting | 6-minute Stepper Test and Pulmonary Rehabilitation in Patients With Severe to Very Severe Chronicle Obstructive Pulmonary Disease | August 1, 2019 | September 30, 2023 | |
| NCT05638776 | Recruiting | Phase 2 | Treatment of Chronic Obstructive Pulmonary Disease (COPD) With Diffusion Capacity Defect by REGEND001 Cell Therapy | June 20, 2022 | December 2025 |
| NCT04427826 | Recruiting | Phase 1/Phase 2 | Efficacy of Morphine in Reducing the Rate of Early Non-Invasive Ventilation Failure in Acute Exacerbation of Chronic Obstructive Pulmonary Disease, Phase I/IIa | December 8, 2020 | January 2027 |
| NCT04995848 | Recruiting | N/A | Telepalliation - Digital Platform for Patients in Palliation and Their Relatives | May 26, 2021 | August 1, 2024 |
| NCT06096285 | Recruiting | Heterogeneity and Development of Early COPD | February 1, 2023 | January 31, 2025 | |
| NCT05862545 | Recruiting | Outcomes in Real-life After Initation of Treatment With Trixeo (Budesonide / Glycopyrronium / Formoterol) | June 1, 2023 | June 30, 2025 | |
| NCT04298606 | Recruiting | Early Phase 1 | A Vaccine (CIMAvax-EGF) for the Prevention of Lung Cancer Development or Recurrence | November 22, 2021 | November 22, 2024 |
| NCT05631132 | Recruiting | N/A | May Noninvasive Mechanical Ventilation (NIV) and/or Continuous Positive Airway Pressure (CPAP) Increase the Bronchoalveolar Lavage (BAL) Salvage in Patients With Pulmonary Diseases? | September 4, 2022 | June 1, 2024 |
| NCT04700098 | Recruiting | N/A | Internet-based Cognitive-behavioral Treatment for Insomnia in COPD Patients Undergoing Pulmonary Rehabilitation | February 14, 2022 | March 31, 2025 |
| NCT05437198 | Recruiting | Study of Microbiological Diversity in Exhaled Air in COPD and Free of COPD | March 26, 2024 | March 2029 | |
| NCT05743075 | Recruiting | Phase 3 | A Study to Evaluate the Efficacy and Safety of Ensifentrine for 24 Weeks in Patients With Moderate to Severe Chronic Obstructive Pulmonary Disease | March 10, 2023 | February 1, 2025 |
| NCT06068647 | Recruiting | N/A | Ultrasound and Respiratory Physiological Signals in Lung Diseases | March 22, 2023 | March 31, 2025 |
| NCT05896800 | Recruiting | N/A | A Clinical Study of Inhaled Nitric Oxide in Moderate-to-Severe Chronic Obstructive Pulmonary Disease | June 7, 2023 | June 30, 2024 |
| NCT06432972 | Recruiting | N/A | Accelerated Pulmonary Rehabilitation in the Preoperative Period | January 2, 2024 | December 31, 2025 |
| NCT06335992 | Recruiting | N/A | Tissue Regeneration in Patients With Chronic Obstructive Pulmonary Disease After an Exercise Intervention. | September 1, 2022 | April 30, 2025 |
| NCT04571983 | Recruiting | Influence of Reliance on Historical Blood Eosinophil Counts on ICS Prescribing by GOLD 2019 Thresholds in COPD | October 26, 2020 | October 31, 2023 | |
| NCT05989698 | Recruiting | N/A | C-mo System 1.0's Validation - Cough Monitoring | December 11, 2023 | June 11, 2025 |
| NCT05676502 | Recruiting | N/A | Effects on Ventilation With NHF and Asymmetrical Nasal Cannulas | January 19, 2023 | April 1, 2024 |
| NCT06208306 | Recruiting | Phase 3 | A Study to Investigate Long-term Safety and Tolerability of Itepekimab in Participants With COPD | January 11, 2024 | December 1, 2026 |
| NCT05052125 | Recruiting | Phase 4 | Substudy of Protocol 2019-002498-80 - NCT04223050: Comparing Mortality for Low vs High Peripheral Oxygen Saturation in COPD-patients With Acute Exacerbation (O2flow-COPD) | December 16, 2021 | August 2024 |
| NCT03049202 | Recruiting | BROnchoalveolar Investigations of Never-smokers With Chronic Obstruction From the Swedish CardioPulmonary bioImage Study | February 1, 2017 | December 31, 2028 | |
| NCT05772013 | Recruiting | Phase 4 | Optimising Azithromycin Prevention Treatment in COPD to Reduce Exacerbations | March 5, 2024 | November 2028 |
| NCT05473780 | Recruiting | Oxygen Therapy Remote Monitoring in COPD Patients. | January 27, 2023 | January 27, 2025 | |
| NCT06041126 | Recruiting | The Effect of Clinical Parameters on Muscle Oxygenation in Patients With COPD | April 24, 2023 | November 23, 2023 | |
| NCT05295355 | Recruiting | N/A | Effect of Tiotropium Bromide Combined With Odaterol on Small Airway Remodeling in Patients With Mild to Moderate Chronic Obstructive Pulmonary Disease | January 25, 2021 | March 2025 |
| NCT05646407 | Recruiting | N/A | Move With Air: Exercise Training Study | April 1, 2023 | March 30, 2025 |
| NCT05832814 | Recruiting | N/A | Music Therapy for COPD Rehabilitation | February 3, 2023 | December 2023 |
| NCT05746039 | Recruiting | Phase 1/Phase 2 | Feasibility of Semaglutide in Advanced Lung Disease | January 29, 2024 | June 28, 2024 |
| NCT05306743 | Recruiting | N/A | PRagmatic EVAluation of a Quality Improvement Program for People Living With Modifiable High-risk COPD. | September 23, 2022 | December 2026 |
| NCT05492448 | Recruiting | N/A | Probiotic on Type 2 Diabetes and Chronic Obstruction Pulmonary Disease | September 19, 2022 | December 31, 2024 |
| NCT06330623 | Recruiting | Developing Personalised Relative Physical Activity Thresholds in COPD. | November 22, 2023 | September 1, 2025 | |
| NCT03987633 | Recruiting | EMPOWER-1: A Multi-site Clinical Cohort Research Study to Reduce Health Inequality | February 1, 2021 | February 1, 2028 | |
| NCT05775588 | Recruiting | N/A | Long-term Effects of Endobronchial Valve Implantation on Cardiac Function and Skeletal Muscle Function | March 27, 2023 | December 31, 2024 |
| NCT05830318 | Recruiting | Usability and Acceptability Study of the P-STEP Mobile Application | August 23, 2023 | January 31, 2024 | |
| NCT05607719 | Recruiting | Phase 2 | Inhaled Corticosteroids (ICS) on Pulmonary Endothelial Function in COPD | April 11, 2023 | April 30, 2025 |
| NCT04550741 | Recruiting | N/A | Long-term Maintenance Benefits of a Pulmonary Rehabilitation Program Using a Mobile Digital Solution: a Prospective, Randomized, Controlled, Multicenter Study in a Population of COPD Patients | March 10, 2022 | May 2025 |
| NCT05786950 | Recruiting | N/A | Neural Respiratory Drive of Patients With Chronic Obstructive Pulmonary Disease | January 1, 2023 | September 1, 2023 |
| NCT04163536 | Recruiting | Phase 3 | Comparison of Corticosteroids vs Placebo on Duration of Ventilatory Support During Severe Acute Exacerbations of COPD Patients in the ICU | October 25, 2021 | March 1, 2026 |
| NCT01037387 | Recruiting | Phase 4 | Effect of Noninvasive Ventilation on Physical Activity and Inflammation in COPD Patients | December 2025 | December 2025 |
| NCT05314686 | Recruiting | Telerehabilitation - Technical Validity and Clinical Feasibility | November 15, 2022 | March 31, 2024 | |
| NCT05622864 | Recruiting | Phase 1 | Study on Single and Multiple Atomization Inhalation of HRS-9821 Suspension for Inhalation in Healthy Subjects | January 12, 2023 | September 30, 2023 |
| NCT05987371 | Recruiting | Phase 2 | A Clinical Trial of TQC3721 Suspension for Inhalation in Patients With Moderate to Severe Chronic Obstructive Pulmonary Disease. | August 23, 2023 | March 2024 |
| NCT06035393 | Recruiting | Phase 2 | A Study to Assess the Efficacy and Safety of HRG2005 Inhalation in Patients With Moderate to Severe Chronic Obstructive Pulmonary Disease | January 15, 2024 | August 28, 2025 |
| NCT05553223 | Recruiting | N/A | Micro-doses of Physical Activity for COPD | October 12, 2022 | September 1, 2024 |
| NCT06434792 | Recruiting | Phase 2 | Study to Evaluate Efficacy and Safety of Bronpass Tab. in Patients With Chronic Obstructive Pulmonary Disease | June 1, 2023 | March 2025 |
| NCT05351242 | Recruiting | N/A | Thermotherapy Against Persistent Bacterial LUNG Infections | January 31, 2023 | September 2026 |
| NCT05239793 | Recruiting | N/A | Electronic Cigarette-derived Oxidants and Cardiopulmonary Effects | November 22, 2022 | November 2024 |
| NCT04628962 | Recruiting | Raman Analysis of Saliva as Biomarker of COPD | February 1, 2022 | January 1, 2025 | |
| NCT06125665 | Recruiting | N/A | Aminophylline on Perioperative Lung Mechanics in COPD Morbidly Obese Patients Undergoing Laparoscopic Bariatric Surgery | November 11, 2023 | April 1, 2024 |
| NCT05664945 | Recruiting | N/A | Rethinking Pulmonary Rehabilitation | January 10, 2023 | July 31, 2026 |
| NCT05234281 | Recruiting | N/A | Concentrated Cross-disciplinary Group Intervention for Common Health Complaints (Including Post COVID-19 Fatigue) | May 1, 2021 | May 1, 2024 |
| NCT06282861 | Recruiting | Phase 4 | ANTES B+ Clinical Trial | February 29, 2024 | September 2025 |
| NCT05315505 | Recruiting | N/A | Effectiveness of a Home-based Pulmonary Rehabilitation Program in COPD Patients | May 9, 2022 | April 2024 |
| NCT05638646 | Recruiting | N/A | A COPD Quality Improvement Program（QIP） | November 25, 2022 | December 31, 2024 |
| NCT06172946 | Recruiting | N/A | Effect of Powerbreath Versus Transcutaneous Electrical Diaphragmatic Stimulation on The Severity of Copd | December 12, 2023 | April 2024 |
| NCT05964491 | Recruiting | Video Resources for People With Chronic Obstructive Pulmonary Disease: An Exploratory Qualitative Study | October 20, 2022 | May 31, 2024 | |
| NCT03331302 | Recruiting | Phase 1/Phase 2 | Hyper Polarized Xenon-129 MRI vs Xenon-133 Scintigraphy | September 1, 2018 | December 31, 2020 |
| NCT04983472 | Recruiting | Comparison of Respiratory Muscle Activations During Dyspnea Reduction Positions in Individuals | July 20, 2021 | May 20, 2023 | |
| NCT05605548 | Recruiting | Early Phase 1 | Mitochondrial Derived Reactive Oxygen Species on Cardiovascular Health in Chronic Obstructive Pulmonary Disease (COPD) | February 16, 2023 | December 2025 |
| NCT05808621 | Recruiting | Muscle Oxygenation in Chronic Obstructive Pulmonary Disease | March 8, 2023 | August 23, 2023 | |
| NCT03002389 | Recruiting | Phase 2 | Hyperpolarized Xenon-129 MRI: a New Multi-dimensional Biomarker to Determine Pulmonary Physiologic Responses to COPD Therapeutics | November 5, 2017 | January 31, 2025 |
| NCT05287555 | Recruiting | N/A | Efficacy of Telemetry-assisted Care in Home Home Vented COPD | April 25, 2022 | October 1, 2024 |
| NCT04963192 | Recruiting | N/A | Integrated Management of Chronic Respiratory Diseases | September 10, 2021 | February 28, 2025 |
| NCT03455686 | Recruiting | N/A | Exploring the Utility of Hyperpolarized 129Xe MRI in Healthy Volunteers and Patients With Lung Disease | April 19, 2018 | December 2024 |
| NCT03989271 | Recruiting | Phase 1/Phase 2 | Biological Effects of Quercetin in COPD | October 1, 2019 | July 1, 2025 |
| NCT03651895 | Recruiting | Phase 2 | Metformin to Reduce Airway Glucose in COPD Patients | May 17, 2022 | June 1, 2023 |
| NCT04180670 | Recruiting | Prevalence of Urinary Incontinence and Evaluation of Related Factors in Patients With COPD | December 1, 2019 | September 2023 | |
| NCT03890224 | Recruiting | N/A | Respiratory Support in Chronic Obstructive Pulmonary Disease (COPD) Patients | July 4, 2019 | December 31, 2024 |
| NCT04751487 | Recruiting | Phase 3 | Study to Assess the Efficacy, Safety, and Tolerability of SAR440340/REGN3500/Itepekimab in Chronic Obstructive Pulmonary Disease (COPD) (AERIFY-2) | February 12, 2021 | October 17, 2025 |
| NCT05785195 | Recruiting | N/A | A Mechanistic Study of Inhaled Nitric Oxide in COPD | March 14, 2023 | March 31, 2024 |
| NCT05939999 | Recruiting | N/A | Effects of Elastic Tape on Pulmonary Rehabilitation of Patients With Chronic Obstructive Pulmonary Disease | October 26, 2023 | June 2024 |
| NCT05575791 | Recruiting | Evaluation of Preoperative Acceptance of Proactive Palliative Care Intervention | December 1, 2022 | November 30, 2023 | |
| NCT02237820 | Recruiting | Phase 4 | Dexamethasone Versus Prednisone in Heart Failure Patients, Hospitalized With Exacerbation of Chronic Obstructive Pulmonary Disease. | November 2014 | June 2025 |
| NCT03450603 | Recruiting | Predicting Risk Factors for Exacerbation of Chronic Obstructive Pulmonary Disease | December 10, 2017 | December 30, 2024 | |
| NCT04843696 | Recruiting | N/A | Negative Pressure Ventilation-rehabilitation on Acute Exacerbation of Chronic Obstructive Pulmonary Disease | April 8, 2021 | December 31, 2024 |
| NCT04236726 | Recruiting | Investigating Health Related Quality of Life in Patients With Chronic Respiratory Failure | December 19, 2019 | May 31, 2025 | |
| NCT06035276 | Recruiting | N/A | Biosensor and Environmental Sensor Development Within the REMEDIA Project | August 28, 2023 | September 30, 2024 |
| NCT05552833 | Recruiting | N/A | Pulmonary Adaptive Responses to HIIT in COPD | September 5, 2022 | August 1, 2024 |
| NCT05905874 | Recruiting | Machine Learning-based Models in Prediction of DVT and PTE in AECOPD Patients | January 1, 2023 | December 31, 2024 | |
| NCT02966665 | Recruiting | Phase 1 | : Vascular Function in Health and Disease | September 2008 | August 2025 |
| NCT04701983 | Recruiting | Phase 3 | Study to Assess the Efficacy, Safety, and Tolerability of SAR440340/REGN3500/Itepekimab in Chronic Obstructive Pulmonary Disease (COPD) | December 16, 2020 | November 28, 2025 |
| NCT03566667 | Recruiting | Phase 4 | Beta-blockers to Patients With Chronic Obstructive Pulmonary Disease | June 12, 2018 | December 31, 2024 |
| NCT05562037 | Recruiting | N/A | Stepped Care vs Center-based Cardiopulmonary Rehabilitation for Older Frail Adults Living in Rural MA | September 8, 2022 | February 28, 2025 |
| NCT05506202 | Recruiting | N/A | Basic Body Awareness Therapy (BBAT) for Patients With Chronic Obstructive Pulmonary Disease | August 1, 2022 | October 31, 2023 |
| NCT05813652 | Recruiting | Relative Impacts on Preventative Primary Care--a Longitudinal Evaluation of COVID-19:Phase 1 | October 5, 2022 | March 31, 2025 | |
| NCT05196698 | Recruiting | N/A | Home High Flow Oxygen to Reduce Acute Exacerbation of COPD | August 26, 2022 | August 26, 2026 |
| NCT05618847 | Recruiting | N/A | Effects of Active Cycle of Breathing Technique With and Without Acapella on Airway Clearance | May 1, 2022 | February 2023 |
| NCT06046547 | Recruiting | N/A | Integrating Palliative Care Education in Pulmonary Rehabilitation | September 1, 2023 | June 2026 |
| NCT05844462 | Recruiting | Phase 3 | Tadalafil for Severe Pulmonary Hypertension Due to Chronic Obstructive Pulmonary Disease | February 1, 2024 | September 2026 |
| NCT06332417 | Recruiting | N/A | Combined Effects of Ba-Duan-Jin Based Deep Breathing Exercises and Forced Expiratory Technique | February 29, 2024 | June 15, 2024 |
| NCT05309356 | Recruiting | N/A | Using Clinical Prediction Models to Improve Treatment for Patients With Chronic Obstructive Pulmonary Disease (COPD) | March 21, 2023 | July 2025 |
| NCT06271408 | Recruiting | Phase 1 | Comparison of Bronchodilator Response From Three Different Aerosol Delivery Methods in Patients With COPD Using Hyperpolarized Xe 129 MRI Ventilation Imaging | February 2024 | April 2024 |
| NCT05209880 | Recruiting | N/A | Advance Care Planning in the Emergency Department | March 1, 2022 | June 30, 2024 |
| NCT04008615 | Recruiting | Comparison of the Cardiopulmonary and Gaz-exchange Response Between the Six-minute Stepper Test and the Incremental Cardiopulmonary Exercise Testing in Patients With Chronicle Obstructive Pulmonary Disease | August 1, 2019 | September 30, 2023 | |
| NCT03591263 | Recruiting | Clinical Outcomes in Patients Referred to Pulmonary Rehabilitation | June 25, 2018 | June 25, 2024 | |
| NCT06188065 | Recruiting | Eosinopenia in Severe COPD Exacerbation | January 22, 2024 | July 2026 | |
| NCT05572346 | Recruiting | Digital App for Telerehabilitation in Respiratory Diseases | October 17, 2022 | January 2024 | |
| NCT06358235 | Recruiting | N/A | The Effect of Music Therapy on Dyspnea Severity and Vital Signs | January 7, 2024 | June 30, 2024 |
| NCT05984498 | Recruiting | Understanding Balance Impairment in COPD | July 17, 2023 | May 1, 2024 | |
| NCT06390631 | Recruiting | N/A | Effect of CPAP on Respiratory Load in COPD | May 1, 2024 | July 10, 2024 |
| NCT06207331 | Recruiting | N/A | Effects of Atomized Dexmedetomidine on Lung Function in Patients With Chronic Obstructive Pulmonary Disease | October 28, 2023 | December 31, 2025 |
| NCT06253013 | Recruiting | N/A | CHARM-COPD Program of Care | September 15, 2023 | June 2025 |
| NCT05667363 | Recruiting | N/A | Digital Therapeutics on Inhalation Medication Adherence in COPD | December 20, 2022 | September 1, 2023 |
| NCT05349123 | Recruiting | N/A | A Home-based Intervention to Promote Mindful Breathing Awareness Through Pursed-lip Breathing Training for COPD Patients | January 10, 2022 | April 15, 2024 |
| NCT05061368 | Recruiting | Phase 2 | Oral Sildenafil for Exercise Capacity, Dyspnea and Cardiopulmonary Function in COPD | March 1, 2022 | June 2025 |
| NCT05565872 | Recruiting | N/A | Effects of Supervision During a Community-based Exercise Intervention (Urban Training) in Patients With COPD | October 5, 2022 | November 15, 2024 |
| NCT05806294 | Recruiting | N/A | Digital Metabolic Rehabilitation COPD | November 17, 2022 | September 2024 |
| NCT05759247 | Recruiting | N/A | Evaluation of the Use of a Remote Monitoring and Follow-up Option for Patients With Chronic Obstructive Pulmonary Disease (BOREAL) | June 19, 2023 | December 2025 |
| NCT05723185 | Recruiting | Primary Care-Hospital Embedding: a Prospective, Multicentric, Observational Study | February 13, 2023 | January 31, 2024 | |
| NCT05185856 | Recruiting | N/A | Visa-versa! Breaking Instead of Pushing the Pedals-B | February 15, 2022 | December 31, 2024 |
| NCT05785026 | Recruiting | N/A | Menthol for Dyspnea Relief in Health and COPD | January 1, 2023 | June 30, 2027 |
| NCT03799354 | Recruiting | N/A | Study on Impact of Maximal Strength Training in Patients With COPD | September 18, 2019 | September 30, 2024 |
| NCT04986332 | Recruiting | N/A | Multidimensional Approach for COPD and High Complexity | September 1, 2021 | September 1, 2026 |
| NCT06361862 | Recruiting | N/A | Does Continuous Vital Sign Monitoring Increase Investigations and Interventions in Complication-free Patients? | January 1, 2024 | April 1, 2025 |
| NCT05746702 | Recruiting | Investigation of Arm Swings Characteristics in Patient With Chronic Obstructive Pulmonary Disease | March 1, 2023 | October 19, 2024 | |
| NCT04636801 | Recruiting | Phase 3 | A 52-week, Placebo-controlled Study to Evaluate the Efficacy and Safety of 2 Doses of CHF6001 DPI (Tanimilast), as add-on to Maintenance Triple Therapy in Subjects With COPD and Chronic Bronchitis (PILASTER) | July 14, 2021 | June 20, 2025 |
| NCT05227547 | Recruiting | N/A | Mapping and Characterization of Alveolar Cells During Smoking and Chronic Obstructive Disease | October 5, 2022 | October 5, 2030 |
| NCT05543720 | Recruiting | N/A | Evaluation of Nurse-led Integrated Care of Complex Patients Facilitated By Telemonitoring: The SMaRT Study | October 17, 2022 | September 2025 |
| NCT06271122 | Recruiting | N/A | Identification of Explanatory Factors for the Lack of Muscle Strength Gain Following a Pulmonary Rehabilitation Program in COPD Patients | January 18, 2024 | May 16, 2025 |
| NCT05914285 | Recruiting | N/A | Assessment of Salbutamol Effect on Arterial Oxygenation in COPD Patients During One-lung Ventilation | April 25, 2023 | April 21, 2025 |
| NCT04918095 | Recruiting | CareCOPD - COPD Home Monitoring Study | November 9, 2020 | July 31, 2023 | |
| NCT04932811 | Recruiting | The Lung Microbiome and Endobronchial Valve Treatment | June 16, 2021 | June 30, 2025 | |
| NCT05878769 | Recruiting | Phase 3 | A Study to Evaluate the Long-Term Safety of Astegolimab in Participants With Chronic Obstructive Pulmonary Disease (COPD) | June 28, 2023 | June 30, 2027 |
| NCT05706402 | Recruiting | Phase 3 | N-acetylcysteine (NAC) for the Treatment of Acute Exacerbation of COPD | September 18, 2023 | September 30, 2025 |
| NCT02915614 | Recruiting | N/A | Effects of Pulmonary Rehabilitation on Skeletal Muscle in COPD Patients | March 2, 2017 | January 2024 |
| NCT06206551 | Recruiting | Implementing Spiritual Care in Inpatient Palliative Care | December 1, 2023 | December 31, 2024 | |
| NCT03014609 | Recruiting | Cardiovascular Risk and Chronic Obstructive Pulmonary Disease | January 9, 2017 | December 2029 | |
| NCT03221101 | Recruiting | N/A | Home Non Invasive Ventilation for COPD Patients | December 2011 | December 2025 |
| NCT04825067 | Recruiting | N/A | Remote Monitoring of High-Risk Patients With Chronic Cardiopulmonary Diseases | April 1, 2022 | December 31, 2022 |
| NCT01177618 | Recruiting | Boston Early-Onset Chronic Obstructive Pulmonary Disease (COPD) Study | July 1994 | July 2027 | |
| NCT05649423 | Recruiting | N/A | Postural Drainage With and Without Percussion in Chronic Obstructive Pulmonary Disease | April 10, 2022 | February 15, 2023 |
| NCT05826613 | Recruiting | Respiratory Registry for Lung Health: a Prospective, Observational Study on Adult Patients With Asthma or COPD | September 10, 2019 | May 31, 2024 | |
| NCT06395610 | Recruiting | Phase 1 | Effect of Erythromycin on the Absorption, Metabolism and Elimination of CHF6001 in Healthy Volunteers | March 28, 2024 | July 27, 2024 |
| NCT05906264 | Recruiting | N/A | Pulmonary Rehabilitation Program in COPD Patient | June 9, 2022 | September 30, 2023 |
| NCT06163131 | Recruiting | The Effect of Treatment of Emphysema With Endobronchial Valves on the Diaphragm Mobility | November 27, 2023 | April 1, 2027 | |
| NCT05399056 | Recruiting | N/A | Improving Participation in Pulmonary Rehabilitation Through Peer Support and Storytelling | February 24, 2023 | August 31, 2026 |
| NCT05292950 | Recruiting | Phase 1 | Study of ARO-MUC5AC in Healthy Subjects and Patients With Muco-Obstructive Lung Disease | June 27, 2022 | November 2024 |
| NCT05853081 | Recruiting | FODEPOC Study: Fat-free Mass Index in Copd | September 22, 2023 | December 31, 2024 | |
| NCT05326412 | Recruiting | Phase 2 | Mechanistic Study of the Effect of Itepekimab on Airway Inflammation in Patients With COPD | May 19, 2022 | March 20, 2025 |
| NCT06220851 | Recruiting | Correlation Between Handgrip Strength and Air Trapping in Patients With Stable Chronic Obstructive Pulmonary Disease | February 20, 2024 | May 31, 2024 | |
| NCT05711654 | Recruiting | N/A | Chronic Obstructive Pulmonary Disease and Health Coaching | December 1, 2022 | September 30, 2023 |
| NCT00307281 | Recruiting | Emphysema Research Registry and Biosample Repository | August 2000 | July 2030 | |
| NCT05119556 | Recruiting | N/A | Video Telehealth Pulmonary Rehabilitation to Reduce Hospital Readmission in Chronic Obstructive Pulmonary Disease | June 28, 2022 | August 31, 2027 |
| NCT06436482 | Recruiting | Research of Endobronchial Optical Coherence Tomography in Pre-COPD | March 1, 2023 | July 1, 2024 | |
| NCT06459843 | Recruiting | N/A | Effects Of of Pursed Lip Breathing and Coordinated Breathing in Adult Patients With COPD | January 15, 2024 | July 15, 2024 |
| NCT04339270 | Recruiting | Phase 4 | Chronic Airway Disease, Mucus Rheology and Exacerbations | February 3, 2023 | February 2026 |
| NCT04966221 | Recruiting | Functional and Structural Lung Imaging in Chronic Obstructive Pulmonary Disease | January 1, 2022 | August 1, 2024 | |
| NCT03120481 | Recruiting | Controls for Respiratory Diseases | April 10, 2017 | February 28, 2037 | |
| NCT06077994 | Recruiting | N/A | Enhanced Pulmonary Rehabilitation With Digital Remote Home Monitoring | August 29, 2023 | October 2024 |
| NCT05690009 | Recruiting | Real Clinical Practice Register of AlbUminuRia Detection in Patients With Previously undiAgnosed Chronic Kidney Disease | February 27, 2023 | December 31, 2023 | |
| NCT05583396 | Recruiting | N/A | Pulmonary Diffusing Capacity During Acute Exercise in Patients With COPD | November 1, 2022 | August 1, 2023 |
| NCT05237505 | Recruiting | Phase 2 | The Cardiovascular Consequences of Sleep Apnea Plus COPD (Overlap Syndrome) | February 13, 2024 | August 31, 2028 |
| NCT02748798 | Recruiting | Early Phase 1 | Developing Optimal Parameters for Hyperpolarized Noble Gas and Inert Fluorinated Gas MRI of Lung Disorders | November 10, 2020 | December 22, 2023 |
| NCT05454631 | Recruiting | N/A | Tolerance of Surgical Masks in Chronic Respiratory Diseases | February 6, 2023 | October 30, 2023 |
| NCT05659550 | Recruiting | N/A | Move With Air: Physiological Response Assessment | April 1, 2023 | December 30, 2024 |
| NCT05612035 | Recruiting | Phase 2 | MK-5475-013 INSIGNIA-PH-COPD: A Study of the Efficacy and Safety of MK-5475 (an Inhaled sGC Stimulator) in Adults With PH-COPD | March 16, 2023 | March 23, 2028 |
| NCT02924870 | Recruiting | Phase 4 | Long-term Effect of an Health Education Program on Daily Physical Activity in Patients With Moderate to Very Severe Chronic Obstructive Pulmonary Disease | October 2016 | March 2025 |
| NCT05652439 | Recruiting | PASS to Assess Cardiovascular and Cerebrovascular Events in COPD Patients Initiating Fixed Triple Therapy (DPI or pMDI) | December 2, 2022 | August 2026 | |
| NCT04217330 | Recruiting | N/A | An Implementation Trial to Improve Access to Pulmonary Rehabilitation in People With COPD | March 1, 2021 | August 2025 |
| NCT02065921 | Recruiting | Swiss Chronic Obstructive Pulmonary Disease (COPD) Management Cohort | September 2006 | September 2025 | |
| NCT05456906 | Recruiting | Avoidable Hospitalizations/ Emergency Department Visits- Systematic Review and Meta-synthesis of Qualitative Research | June 1, 2022 | August 31, 2022 | |
| NCT04915365 | Recruiting | Phase 3 | Effect of Acetazolamide on Right Heart Function at Rest in Lowlanders With COPD Traveling to High Altitude | May 1, 2021 | December 31, 2023 |
| NCT03840928 | Recruiting | PatientSpot Formerly Known as ArthritisPower | April 1, 2015 | March 1, 2025 | |
| NCT05940480 | Recruiting | N/A | TCM Daoyin Therapy in Individuals At-risk for COPD | January 3, 2023 | December 31, 2027 |
| NCT05799040 | Recruiting | Evaluation of the Effectiveness of the Self-developed Pulmonary Lobar Ventilation Detector | October 26, 2023 | December 31, 2024 | |
| NCT05865184 | Recruiting | Evaluation of Home-based Sensor System to Detect Health Decompensation in Elderly Patients With History of CHF or COPD | September 28, 2022 | June 6, 2024 | |
| NCT06381973 | Recruiting | N/A | Ventilation Distribution in COPD Patients During Breathing Exercises | April 15, 2024 | August 1, 2024 |
| NCT06067828 | Recruiting | Phase 3 | A Study to Evaluate the Effect of Budesonide, Glycopyrronium, Formoterol Fumarate (BGF) Metered Dose Inhaler (MDI), Budesonide and Formoterol Fumarate (BFF) MDI and Placebo MDI on Exercise Parameters in Participants With Chronic Obstructive Pulmonary Disease (COPD). | October 24, 2023 | August 25, 2025 |
| NCT05743582 | Recruiting | Innate Immunity in COPD | May 11, 2023 | February 10, 2028 | |
| NCT06214325 | Recruiting | N/A | Music Therapy to Address Patients' Journeys With Chronic Illness, Outcomes, and Readmission | January 15, 2024 | June 30, 2024 |
| NCT06003270 | Recruiting | Phase 2 | Biological Effects of Quercetin in COPD Phase II | November 1, 2023 | July 31, 2025 |
| NCT05480176 | Recruiting | The China National COPD Screening Program | October 9, 2021 | December 31, 2025 | |
| NCT04277429 | Recruiting | HFpEF and 2-year Mortality of COPD Patients | July 1, 2020 | April 1, 2025 | |
| NCT04263727 | Recruiting | A Study of Patients With Chronic Disease | February 27, 2020 | February 2035 | |
| NCT04636814 | Recruiting | Phase 3 | A 52-week, Placebo- and Active- Controlled (Roflumilast, Daliresp® 500µg) Study to Evaluate the Efficacy and Safety of Two Doses of CHF6001 DPI (Tanimilast) as add-on to Maintenance Triple Therapy in Subjects With COPD and Chronic Bronchitis. (PILLAR) | July 12, 2021 | September 18, 2027 |
| NCT05005533 | Recruiting | The Effect of Respiratory Muscle Strength and Functional Capacity on Posture and Balance | March 15, 2021 | May 15, 2023 | |
| NCT05984823 | Recruiting | N/A | Home-based Body Weight Exercise With Blood Flow Restriction (BFR): Feasibility of a Novel Rehabilitation Intervention in COPD Patients (HomeBFR-COPD) | January 26, 2024 | June 2025 |
| NCT05147688 | Recruiting | Phase 1 | Safety of Cultured Allogeneic Adult Umbilical Cord Derived Mesenchymal Stem Cells for Pulmonary Diseases | December 2021 | December 2025 |
| NCT04849104 | Recruiting | Cohort Study of Airway Microecology and the Pathogenesis and Evolution of Chronic Obstructive Pulmonary Disease | February 26, 2021 | December 31, 2025 | |
| NCT03945968 | Recruiting | The Role of Concomitant Diseases in Postoperative Complications Risk Stratification. | July 1, 2019 | February 28, 2025 | |
| NCT06422676 | Recruiting | MultIceNtre Non-intERVentional Study for Efficacy,Safety Evaluation of BREZTRI in Pts With COPD in RussiA | December 29, 2023 | December 31, 2024 | |
| NCT04350541 | Suspended | N/A | Effects of HIIT in Tolerance to Exercise of Individuals With HF and Coexisting COPD | September 1, 2019 | December 15, 2021 |
| NCT04524819 | Suspended | A Pilot Study to Characterise Saliva and Sputum FTIR Spectral Profiles in Patients With COPD During Exacerbations and When Stable | September 18, 2019 | September 18, 2023 | |
| NCT02528487 | Suspended | Predictors of the Long-term Functional Benefits of a Pulmonary Rehabilitation Program? | May 2015 | March 2023 | |
| NCT03522805 | Terminated | N/A | Impact of Non-invasive Ventilation in Hypercapnic COPD | April 23, 2018 | November 21, 2018 |
| NCT02671942 | Terminated | Phase 2 | A Multicenter Randomized Double-blind Clinical Study Evaluated the Safety, Pharmacokinetic and Pharmacodynamic Characteristics of Roflumilast in COPD Patients | March 2016 | June 13, 2018 |
| NCT00180843 | Terminated | N/A | Assessment of Ventilation-perfusion Abnormalities in Patients With Stable Smoking-related Airways Disease | September 2005 | February 2008 |
| NCT01351792 | Terminated | Phase 3 | A Study in Patients With Chronic Obstructive Pulmonary Disease (FAIR) | September 2011 | November 2012 |
| NCT01384981 | Terminated | N/A | Effects of Non-invasive Ventilation on Rehabilitation Outcome in COPD-patients | January 2011 | September 2013 |
| NCT02815488 | Terminated | Phase 1/Phase 2 | A Study to Investigate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Single and Repeat Doses of CHF6297 in Healthy Subjects and Patients With COPD | January 22, 2016 | March 2019 |
| NCT03496623 | Terminated | Phase 3 | A Phase 3 Adaptive Study to Evaluate the Safety and Efficacy of Inhaled Treprostinil in Participants With Pulmonary Hypertension (PH) Due to Chronic Obstructive Pulmonary Disease (COPD) | May 8, 2018 | October 13, 2022 |
| NCT00783250 | Terminated | Phase 4 | Bronchodilators and Respiratory Mechanics in Chronic Obstructive Pulmonary Disease (COPD) Patients | September 2008 | July 2012 |
| NCT02673892 | Terminated | N/A | Patient Oriented Discharge Summary Impact Study | February 2016 | November 2018 |
| NCT01974180 | Terminated | Smoking-induced EGF-dependent Reprogramming of Airway Basal Cell Function | December 3, 2013 | April 23, 2015 | |
| NCT01554488 | Terminated | Phase 4 | Inhaled Fluticasone Effects on Upper Airway Patency in Obstructive Lung Disease | March 12, 2013 | April 7, 2016 |
| NCT01268072 | Terminated | A Study to Evaluate Biomarkers in Chronic Obstructive Pulmonary Disease | February 2011 | January 2013 | |
| NCT01701934 | Terminated | Phase 2 | Impact of Roflumilast on Visceral Adiposity and Metabolic Profile in Chronic Obstructive Pulmonary Disease | February 2013 | December 2014 |
| NCT02529891 | Terminated | Identification of Volatile Organic Compounds in Exhaled Air During Exacerbation of Chronic Obstructive Pulmonary Disease | August 8, 2014 | October 17, 2017 | |
| NCT04268823 | Terminated | Phase 2 | Clinical Study to Assess the Mode of Action of QBW251 in Patients With Chronic Obstructive Pulmonary Disease (COPD) | September 10, 2020 | September 20, 2022 |
| NCT03135860 | Terminated | Early Phase 1 | Effect iNO on Functional Respiratory Imaging in Subjects With WHO Group 3 Pulmonary Hypertension With COPD on Oxygen | October 2016 | August 21, 2017 |
| NCT00181272 | Terminated | Phase 2 | Macrolides to Prevent Exacerbations of Asthma and Chronic Obstructive Pulmonary Disease | September 2005 | July 2006 |
| NCT04199598 | Terminated | Phase 1 | Relative Bioavailability Study With Abediterol Administered Via Three Different Inhalation Devices in Healthy Volunteers. | January 28, 2020 | April 3, 2020 |
| NCT03794583 | Terminated | Phase 3 | Inhaled Treprostinil in Participants With Pulmonary Hypertension Due to Chronic Obstructive Pulmonary Disease (PH-COPD) | December 21, 2018 | November 29, 2022 |
| NCT02825043 | Terminated | N/A | HFNC Effect on BCSS in Patients With COPD | February 2016 | November 21, 2018 |
| NCT02877641 | Terminated | Phase 2 | Cholecalciferol Supplementation in Strengthening Inspiratory Muscles in Cholecalciferol-Deficient Patients With Chronic Obstructive Pulmonary Disease | April 16, 2014 | February 1, 2017 |
| NCT02161744 | Terminated | Phase 1 | Safety, Tolerability and Preliminary Efficacy of Adipose Derive Stem Cells for Patients With COPD | October 10, 2013 | October 29, 2018 |
| NCT00944437 | Terminated | N/A | Continuous Positive Airway Pressure (CPAP) Ventilation Using a Novel Full-Face Mask Versus Conventional Helmet | May 2008 | July 2010 |
| NCT00710541 | Terminated | N/A | Non-invasive Ventilation in Severe Chronic Obstructive Pulmonary Disease(COPD) | October 2004 | December 2012 |
| NCT00114426 | Terminated | Phase 3 | Effects of NIMV on the Health Status of Chronic Obstructive Pulmonary Disease (COPD )Patients | January 2002 | December 2004 |
| NCT01592656 | Terminated | Phase 2 | Long-term Effects of Non-invasive Ventilation in Hypercapnic Chronic Obstructive Pulmonary Disease (COPD) Patients | February 2011 | October 2013 |
| NCT01766544 | Terminated | Early Phase 1 | Asthma & COPD Guideline Implementation | September 2009 | March 2010 |
| NCT01155310 | Terminated | Phase 3 | Efficacy of Helium/Oxygen Compared to Air/Oxygen in Severe Exacerbation of Chronic Obstructive Pulmonary Disease (COPD) | May 2010 | June 2014 |
| NCT01871246 | Terminated | Acute Exacerbation of COPD and Physical Activity - Preliminary Study | February 2013 | July 1, 2021 | |
| NCT03882372 | Terminated | N/A | Nasal High Flow to Maintain the Benefits of Pulmonary Rehabilitation in Chronic Obstructive Pulmonary Disease Patients | July 22, 2019 | September 1, 2023 |
| NCT00413543 | Terminated | N/A | Pulmonary Rehabilitation for Chronic Obstructive Pulmonary Disease (COPD) Exacerbation | October 2006 | October 2007 |
| NCT04611633 | Terminated | Study in COPD Patients Evaluating the Quality of Life (TRISNOOZE) | January 18, 2021 | September 16, 2021 | |
| NCT01014884 | Terminated | N/A | Coventry Outcomes Study of Seniors (COSS): A Comparative Effectiveness Study to Evaluate the Effect of a Multidisciplinary Team's Intervention on the Incidence of Nonelective Hospitalizations in a Medicare Population | November 2009 | June 2011 |
| NCT01526642 | Terminated | N/A | Home Non-invasive Ventilation for Chronic Obstructive Pulmonary Disease Patients | December 2011 | December 2015 |
| NCT00441701 | Terminated | Phase 2 | Study to Evaluate the Safety and Dose-Range of Navarixin (SCH 527123, MK-7123) in Participants With Moderate to Severe Chronic Obstructive Pulmonary Disease (COPD) (MK-7123-012) | December 1, 2006 | October 1, 2008 |
| NCT02315144 | Terminated | Phase 1 | An Efficacy and Safety Profile of Inhaled TV48108 in Healthy Volunteers and COPD Patients | April 2015 | August 2015 |
| NCT04353661 | Terminated | Phase 2 | A Study Of ¹²⁹XE MRI To Assess Disease Progression In Patients With COPD Treated With Or Without Azithromycin And Standard-of-Care Medications | November 16, 2021 | June 29, 2023 |
| NCT03657082 | Terminated | N/A | Effects of PEP on IC During IT in Patients With COPD | September 15, 2018 | December 30, 2021 |
| NCT03379233 | Terminated | Phase 3 | A Randomized Study to Evaluate the Effect of Reminder Notifications and Motivational/Adaptive Messaging on Treatment Adherence | July 11, 2018 | January 22, 2019 |
| NCT01494896 | Terminated | Impact of Inhaled Treprostinil Sodium on Ventilation Perfusion Matching | November 2011 | December 2014 | |
| NCT01793649 | Terminated | Phase 1 | A Phase 1 Study to Characterize the Effect of GS-5737 Enhancement of Mucociliary Clearance (MCC) in Healthy Subjects | October 2012 | June 2013 |
| NCT02726048 | Terminated | N/A | Simplus and Eson Non-Invasive Ventilation (NIV) Evaluation - Germany | April 2016 | July 2017 |
| NCT00874497 | Terminated | Phase 2 | Pilot Study of Tetomilast in Chronic Obstructive Pulmonary Disease (COPD) Associated With Emphysema | March 2009 | August 2015 |
| NCT04654481 | Terminated | N/A | Study of AffloVest in At-Risk Respiratory Patients During COVID-19 Pandemic | July 20, 2021 | October 19, 2021 |
| NCT02532075 | Terminated | N/A | The Effect of a Respiratory Muscle Warm-up Prior to Exercise in Patients With Chronic Obstructive Pulmonary Disease | February 2016 | October 2016 |
| NCT03584269 | Terminated | N/A | Innovation in NOn Invasive Ventilation in COPD Patients Treated by Long Term Oxygen Therapy | June 28, 2018 | September 23, 2019 |
| NCT03353064 | Terminated | N/A | Telemedicine for Improving Outcome in Inner City Patient Population With Hypercapneic Respiratory Failure | October 18, 2017 | October 26, 2018 |
| NCT01697332 | Terminated | Phase 1/Phase 2 | Functional Applications of Hyperpolarized 129Xe MRI | January 2013 | December 2016 |
| NCT00702156 | Terminated | Phase 2 | Bisoprolol in Patients With Heart Failure and Chronic Obstructive Pulmonary Disease | March 2005 | July 2008 |
| NCT01068184 | Terminated | Phase 1 | A Study to Assess Safety, Tolerability and Pharmacokinetics of of AZD6553 in Healthy Volunteers and Patients With Chronic Obstructive Pulmonary Disease (COPD) | February 2010 | May 2010 |
| NCT05623709 | Terminated | Health Outcomes With CPAP or NIV in Patients With COPD and a Sleep Related Breathing Disorder | July 26, 2022 | March 22, 2024 | |
| NCT00547456 | Terminated | N/A | Consequences of Nocturnal and Daytime Hypoxemia in COPD | October 2005 | June 2013 |
| NCT02100709 | Terminated | N/A | The Effect of NIV on QoL and Exercise Capacity in a COPD Exercise Rehabilitation Program | April 2014 | October 2016 |
| NCT01026207 | Terminated | Portable Monitoring Device for the Diagnosis of Sleep Apnea in Patients With Chronic Obstructive Pulmonary Disease | August 2009 | December 2011 | |
| NCT03823443 | Terminated | COPD Exacerbation Blood and Urine Biomarkers Study | June 7, 2018 | January 8, 2021 | |
| NCT00137956 | Terminated | Phase 3 | Endobronchial Valve for Emphysema PalliatioN Trial (VENT) Cost-effectiveness Sub-Study | December 2004 | |
| NCT04441788 | Terminated | Phase 2 | A Study to Assess the Safety, Tolerability, and Efficacy of ION-827359 in Participants With Mild to Moderate Chronic Obstructive Pulmonary Disease (COPD) With Chronic Bronchitis (CB) | December 22, 2020 | August 9, 2021 |
| NCT01708057 | Terminated | Phase 2 | A Single-dose Study to Investigate the Effects of 4 Different Doses of Inhaled AZD8683 in Chronic Obstructive Pulmonary Disease (COPD) Patients | October 2012 | December 2012 |
| NCT02502201 | Terminated | N/A | Environment Effect on Six-Minute Walk Test Performance | October 2015 | August 30, 2017 |
| NCT02135354 | Terminated | Phase 3 | Azithromycin for Acute Exacerbations Requiring Hospitalization | August 1, 2014 | April 2018 |
| NCT03694431 | Terminated | N/A | Comparative Trial of Home-Based Palliative Care | January 7, 2019 | January 24, 2020 |
| NCT03934749 | Terminated | Non-invasive Home Ventilation in Patients With Severe Hypercapnic Chronic Obstructive Pulmonary Disease | June 27, 2019 | September 27, 2020 | |
| NCT05267418 | Terminated | N/A | Effects of Automated Oxygen Titration Alone or With High Flow Nasal Therapy on Dyspnea and Exercise Tolerance | February 26, 2019 | March 30, 2021 |
| NCT00158847 | Terminated | Phase 4 | Modification Of Disease Outcome In COPD | April 2000 | May 2005 |
| NCT01437878 | Terminated | Phase 2 | Effects of Ventavis in Patients With Pulmonary Hypertension (PH) Secondary to Chronic Obstructive Pulmonary Disease (COPD) | March 2012 | November 2012 |
| NCT02680639 | Terminated | N/A | The Use of High Frequency Oscillations With NIV in Hypercapnic COPD Participants | November 13, 2015 | August 24, 2016 |
| NCT01612793 | Terminated | Vagus Nerve Stimulation for Management of Bronchoconstriction in Patients Hospitalized With COPD Exacerbations | October 2012 | April 2013 | |
| NCT02585752 | Terminated | N/A | A Study of Expiratory Pressure Modulation in Moderate to Severe COPD Patients - Phase 1b | October 1, 2015 | November 24, 2017 |
| NCT03795350 | Terminated | Phase 1 | Lung Deposition of TRIMBOW® pMDI in Healthy Volunteers, Asthmatic and COPD Patients | January 14, 2019 | April 3, 2020 |
| NCT02532426 | Terminated | Influence of Chronic Hypoxia on Oxidative Phenotype in Patients With Chronic Obstructive Pulmonary Disease | May 18, 2012 | September 30, 2017 | |
| NCT00457951 | Terminated | Phase 2 | A Study Designed to Evaluate ODSH in Subjects With Exacerbations of COPD | April 2007 | October 2009 |
| NCT04921332 | Terminated | N/A | Bright Light Therapy for Depression Symptoms in Adults With Cystic Fibrosis (CF) and COPD | September 7, 2021 | March 22, 2022 |
| NCT00472953 | Terminated | Phase 3 | Safety of Inhaled Human Insulin in Subjects With Diabetes Mellitus and Chronic Obstructive Pulmonary Disease (COPD) | May 15, 2007 | March 5, 2008 |
| NCT00467636 | Terminated | N/A | Insulin Therapy in Chronic Obstructive Pulmonary Disease (COPD) Exacerbations | July 2007 | May 2009 |
| NCT01982149 | Terminated | Incorporation of Genetic Expression of Airway Epithelium With CT Screening for Lung Cancer | June 2014 | May 2019 | |
| NCT00523367 | Terminated | N/A | COPD Patients Diagnosed With GERD,COPD Exacerbations After Treatment With High Dose PPI | August 2007 | October 2010 |
| NCT02722304 | Terminated | Phase 3 | Stage 1 Study of ARALAST NP and GLASSIA in A1PI Deficiency | November 2, 2016 | September 14, 2018 |
| NCT02552732 | Terminated | N/A | Nasal High Flow Therapy 30 Day Readmission Study | November 2015 | May 3, 2017 |
| NCT02888444 | Terminated | Phase 3 | Smoking Relapse Prevention Among COPD Ex-smokers | July 31, 2017 | April 13, 2018 |
| NCT03128060 | Terminated | N/A | Expanding Access to Home-Based Palliative Care | August 19, 2017 | March 1, 2019 |
| NCT00628992 | Terminated | N/A | Early Rehabilitation of COPD Patients in ICU | February 2008 | September 2011 |
| NCT00744614 | Terminated | Use Of Capnography As Surrogate Measure Of PC02 In Medical Intensive Care Unit (ICU) Patients | November 2007 | October 2010 | |
| NCT04086953 | Terminated | N/A | Validation of a Walk-Time Limit Test (WTLT) Derived From the 6-Minute Walk Test (6-MWT) in Patients With Chronic Cardiovascular or Respiratory Diseases | February 20, 2020 | January 31, 2024 |
| NCT00221819 | Terminated | N/A | Gases Humidification During Noninvasive Ventilation : Heat and Moisture Exchanger or Heated Humidifier ? | June 2004 | December 2004 |
| NCT00138671 | Terminated | Phase 3 | A One Year Clinical Trial Assessing the Usefulness and Safety of Inhaled Insulin in Diabetics With COPD | January 2003 | September 2008 |
| NCT03810183 | Terminated | Phase 2 | A Proof-of-mechanism Study of Multiple, Oral Doses of Fevipiprant (QAW039) in COPD Patients With Eosinophilia | May 21, 2019 | January 16, 2020 |
| NCT01068145 | Terminated | Phase 1 | Two-Part Study to Evaluate the Dose Response of SCH 527123 on Sputum Neutrophilia Following Ozone Challenge in Healthy Subjects and Chronic Obstructive Pulmonary Disease (COPD) Patients (P05567 AM7) | February 2010 | March 2011 |
| NCT01761006 | Terminated | Evaluation of FeNO During and Following Acute COPD Exacerbation | March 2013 | September 23, 2014 | |
| NCT02756533 | Terminated | N/A | Impact of a Telemonitoring Program on the Rate of Hospitalizations for Worsening of Cardio-respiratory Symptoms in COPD Patients Treated at Home by Long-term Non-invasive Ventilation (NIV) | August 2016 | July 6, 2020 |
| NCT01994915 | Unknown status | N/A | Effects of Occupational Therapy in COPD | December 2013 | July 2017 |
| NCT05218564 | Unknown status | N/A | Air as a Placebo: Increasing the Respiratory Performance of People With COPD Through Simple Expectations of Improvement | February 19, 2020 | December 31, 2022 |
| NCT02240225 | Unknown status | Validation of Chinese SRI Questionnaire | January 2014 | October 2014 | |
| NCT03092648 | Unknown status | Phase 1/Phase 2 | Autologous Bronchial Basal Cells Transplantation for Treatment of Chronic Obstructive Pulmonary Disease (COPD) | March 1, 2017 | February 28, 2019 |
| NCT03889964 | Unknown status | Exercise Capacity in COPD | March 1, 2019 | December 2020 | |
| NCT02437994 | Unknown status | N/A | Pulmonary Rehabilitation Program and PROactive Tool | October 2013 | July 2016 |
| NCT04913961 | Unknown status | N/A | Supine Daoyin in the Treatment of AECOPD | March 1, 2021 | December 31, 2023 |
| NCT02348060 | Unknown status | Outcomes Data of Adipose Stem Cells to Treat Chronic Obstructive Pulmonary Disease | November 2015 | May 2019 | |
| NCT01985750 | Unknown status | Early Phase 1 | Understanding the Importance of Plasticity in the Brain Mechanisms of Dyspnoea Perception | November 2013 | February 2020 |
| NCT00883584 | Unknown status | Phase 2 | IMD-1041 Chronic Obstructive Pulmonary Disease: Proof of Concept (POC) Study | July 2008 | May 2009 |
| NCT00858520 | Unknown status | Serum, Plasma, DNA and Tissue Bank in Chronic Obstructive Pulmonary Disease and Lung Cancer | October 2007 | December 2019 | |
| NCT02050022 | Unknown status | Chronic Obstructive Pulmonary Disease Biomarker Study | April 2013 | December 2021 | |
| NCT02329522 | Unknown status | USCOM For Assessing Patients With COPD | February 2014 | September 2020 | |
| NCT01718496 | Unknown status | Phase 3 | Morphine, Dyspnea, Exercise and COPD | July 2014 | August 2016 |
| NCT00627029 | Unknown status | N/A | Evaluation of Programs of Coordinated Care and Disease Management | September 2000 | December 2016 |
| NCT03131752 | Unknown status | N/A | Early Pulmonary Rehabilitation in Exacerbated COPD Patients | June 7, 2017 | March 7, 2019 |
| NCT01382368 | Unknown status | Phase 4 | Acute Effect of Sildenafil on Exercise Tolerance and Functional Capacity in COPD, IPF and Post Pneumonectomy Patients | September 2011 | September 2013 |
| NCT00419289 | Unknown status | N/A | Optimizing the Effect of COPD Rehabilitation | January 2007 | June 2008 |
| NCT03976700 | Unknown status | Phase 3 | Bufei Jianpi Granule for Delaying Pulmonary Function Decline in Early-Stage COPD | June 2019 | December 2021 |
| NCT04178278 | Unknown status | N/A | The Study for the Reliability and Validity of Incremental Shuttle Walking Test for COPD Patients in Korea | December 1, 2019 | December 31, 2021 |
| NCT05151198 | Unknown status | Smartphone-based Self-management in COPD Patients: A Needs Assessment Survey | December 1, 2021 | December 31, 2022 | |
| NCT02392065 | Unknown status | Chronic Obstructive Pulmonary Disease as a Predictor of Mortality in Cardiac Surgery | March 2015 | March 2018 | |
| NCT02833480 | Unknown status | Phase 2 | A Study to Investigate the Differential Effects of Inhaled Symbicort and Advair on Lung Microbiota | February 2015 | June 2021 |
| NCT04849312 | Unknown status | Prediction of 30-Day Readmission Using Machine Learning | March 20, 2022 | December 1, 2022 | |
| NCT02269800 | Unknown status | Phase 4 | An Efficacy Study of BCS Clearing the Oral Colonized Bacterium in Hospitalized Patients With COPD | October 2014 | July 2015 |
| NCT02901535 | Unknown status | N/A | Tele-spirometry in Primary Care-Randomized Clinical Trial Cluster:Telemedicine in Chronic Obstructive Pulmonary Disease | April 2015 | December 2017 |
| NCT02468635 | Unknown status | N/A | Rehabilitation of Patients With Lung Chronic Obstructive Pulmonary Disease | June 2015 | May 2018 |
| NCT04046666 | Unknown status | N/A | Difference in the Metabolic Characteristics of COPD Patients and Healthy Adults | January 3, 2020 | December 2021 |
| NCT04240353 | Unknown status | RECEIVER: Digital Service Model for Chronic Obstructive Pulmonary Disease (COPD) | August 1, 2018 | July 31, 2021 | |
| NCT04683952 | Unknown status | N/A | Rehabilitation With HHFNC in COPD in Nocturnal NIV | January 1, 2020 | January 2022 |
| NCT03892629 | Unknown status | N/A | Baduanjin Exercise for Patients With GOLD 2-3 Stable COPD on Pulmonary Rehabilitation | April 2019 | December 2019 |
| NCT03844711 | Unknown status | N/A | Transcutaneous Electrical Diaphragmatic Stimulation and Inspiratory Muscle Training in Patients With COPD Exacerbated | February 16, 2019 | November 1, 2021 |
| NCT03010449 | Unknown status | N/A | LVR in Severe Emphysema Using Bronchoscopic Autologous Blood Instillation in Combination With Intra-bronchial Valves | August 24, 2017 | February 2020 |
| NCT02657525 | Unknown status | Acute Exacerbation of Chronic Obstructive Pulmonary Disease Inpatient Registry Study | January 2016 | January 2020 | |
| NCT03282526 | Unknown status | N/A | Volume Parameters vs Flow Parameters in Assessment of Reversibility in Chronic Obstructive Pulmonary Disease | September 30, 2017 | December 2018 |
| NCT03050424 | Unknown status | Phase 2 | Iron and Chronic Obstructive Pulmonary Disease (COPD) Exercise Trial | April 1, 2017 | January 1, 2019 |
| NCT04326855 | Unknown status | N/A | Validation of an Intermittent Shuttle Walking Protocol in Patients With COPD | October 1, 2020 | September 30, 2022 |
| NCT02547558 | Unknown status | Phase 4 | Pulmonary Gas Exchange Response to Indacaterol in COPD | October 2015 | November 2015 |
| NCT03359915 | Unknown status | N/A | GECo: Implementation and Effectiveness of COPD Self Management Action Plans in Low and Middle Income Countries | December 2017 | February 2020 |
| NCT05219773 | Unknown status | N/A | Clinic Versus Home Spirometry | December 14, 2021 | May 2022 |
| NCT03010592 | Unknown status | Studying the Airway Microenvironment in Patients Undergoing Surgical and Bronchoscopic Interventions for COPD | February 6, 2017 | January 1, 2023 | |
| NCT01576068 | Unknown status | Early Phase 1 | Chronic Obstructive Pulmonary Disease Case Finding in Community-pharmacies by Spirometry | October 2010 | June 2013 |
| NCT04995510 | Unknown status | Respiratory Muscle Function, Diaphragm Thickness and Health Related Physical Fitness Parameters in Individuals | July 12, 2021 | December 18, 2021 | |
| NCT05591781 | Unknown status | N/A | High Frequency Chest Wall Oscillations Versus Lung Flute in Chronic Obstructive Pulmonary Disease Post(SARS-CoV-2) | October 2022 | December 2022 |
| NCT00120978 | Unknown status | Phase 4 | Can Advair and Flovent Reduce Systemic Inflammation Related to Chronic Obstructive Pulmonary Disease (COPD)? A Multi-Center Randomized Controlled Trial | December 2004 | August 2006 |
| NCT04242030 | Unknown status | N/A | The Microcirculatory Characteristics of the Heart and Lung Meridians: A Study of COPD Patients and Healthy Adults | February 2020 | December 2021 |
| NCT03793192 | Unknown status | N/A | Promoting Activity After COPD Exacerbations, Aim 2 | March 18, 2019 | May 2022 |
| NCT04076085 | Unknown status | N/A | Effect of Extremity Exercise in COPD | September 1, 2019 | April 27, 2021 |
| NCT03900195 | Unknown status | N/A | The Effectiveness of Bottle-PEP in Chronic Obstructive Pulmonary Disease | January 21, 2019 | January 2020 |
| NCT02289573 | Unknown status | Phase 3 | Effects of NAVA and PSV to AECOPD Patients' Air Distribution and Dead Space | November 2014 | June 2015 |
| NCT03364829 | Unknown status | Phase 4 | Utilizing Wearable Device to Observe the Clinical Response of COPD Patients Treated With Combined Bronchodilator and Home-based Pulmonary Rehabilitation Program | January 1, 2016 | June 30, 2018 |
| NCT05192083 | Unknown status | N/A | A Pilot Trial of a Smartphone-based Self-management Support Program for COPD Patients | January 2, 2022 | May 31, 2022 |
| NCT00884975 | Unknown status | Exacerbations and Health Related Quality of Life in Chronic Obstructive Pulmonary Disease | May 2002 | June 2009 | |
| NCT04005833 | Unknown status | Blood Fibrocytes During an Exacerbation and Lung Function Decline in Patients With COPD in Primary Care. | September 19, 2019 | June 1, 2023 | |
| NCT03071731 | Unknown status | N/A | Glittre ADL-test: Responsiveness to Acute Bronchodilation in Chronic Obstructive Pulmonary Disease (COPD) | April 13, 2017 | June 15, 2019 |
| NCT05045742 | Unknown status | Prediction of Patient Deterioration Using Machine Learning | March 20, 2021 | December 1, 2021 | |
| NCT04196699 | Unknown status | N/A | Evaluating the Feasibility, Acceptability and Pre Testing the Impact of a Self-management and Tele Monitoring Program for COPD Patients in Lebanon | January 10, 2020 | June 28, 2020 |
| NCT05271474 | Unknown status | N/A | COPD Remote Patient Monitoring Through Connected Devices | June 2022 | August 2022 |
| NCT04536675 | Unknown status | Phase 3 | Effect of Perioperative Bronchodilator in COPD Patients Undergoing Lung Cancer Surgery | April 1, 2021 | April 2024 |
| NCT04146948 | Unknown status | The Differences of Muscle Activity Between Patients With COPD and Healthy Adults | January 22, 2020 | December 2021 | |
| NCT00279136 | Unknown status | Towards Restoring the Physiological Inhibition of Airway Narrowing in Asthma | September 2004 | March 2006 | |
| NCT02820064 | Unknown status | N/A | Effects of Hypoxia and Inflammation on Citrulline Synthesis by Ornithine Transcarbamylase in Human Enterocytes | January 2016 | January 2017 |
| NCT04834089 | Unknown status | Phase 1/Phase 2 | Clinical Trial for Assessment of Anti-SARS-CoV-2 Serum for Early Treatment of COVID-19 Cases | May 2021 | May 2022 |
| NCT01724684 | Unknown status | N/A | Feasibility and Effectiveness of Telehealth in Patients With Chronic Obstructive Pulmonary Disease in Taiwan | December 2011 | |
| NCT00320333 | Unknown status | COPD Rehabilitation in Primary and Secondary Health Care | December 2004 | December 2007 | |
| NCT04950023 | Unknown status | Small Bioactive Molecules in Early COPD Diseases | May 11, 2021 | May 11, 2024 | |
| NCT05299385 | Unknown status | Phase 3 | The Study for Evaluating the Clinical Effectiveness and Safety of Respiratory Rehabilitation Software 'Redpill Breath'(COPD, Asthma, Lung Cancer, Etc.) | January 13, 2022 | June 30, 2022 |
| NCT02311114 | Unknown status | Program Evaluation of Telehomecare: TeLeCare Study | June 2014 | September 2018 | |
| NCT03797768 | Unknown status | N/A | Community-based Management of Chronic Obstructive Pulmonary Disease in Nepal | December 25, 2019 | September 30, 2021 |
| NCT01671540 | Unknown status | N/A | Effects of IPV Assessed With Functional Imaging | September 2011 | |
| NCT04000958 | Unknown status | N/A | PIFR-based Inhalation Therapy in Patients Recovering From AECOPD | September 1, 2019 | July 1, 2021 |
| NCT01902927 | Unknown status | N/A | Modulation of Dyspnea Perception During Exercise in COPD Patients Using Attentional Distraction | July 2013 | October 2013 |
| NCT04639349 | Unknown status | N/A | Effect of Home Exercise Activity on Cortisol and Depression in COPD During the Pandemic COVID | November 19, 2020 | March 1, 2021 |
| NCT00864994 | Unknown status | Multiorgan Pathology in Chronic Obstructive Pulmonary Disease (COPD) | September 2010 | April 2015 | |
| NCT01198288 | Unknown status | Phase 3 | Effects of Home-based Pulmonary Rehabilitation in Patients With Severe or Very Severe Chronic Obstructive Pulmonary Disease (COPD) | September 2010 | September 2012 |
| NCT04108143 | Unknown status | N/A | Use of MonitorMe in COPD | February 11, 2020 | December 31, 2022 |
| NCT01595750 | Unknown status | Phase 4 | Randomized, Double-blind, Placebo-controlled Study to Evaluate the Effect of Roflumilast on Endothelial Function in Patients With Chronic Obstructive Pulmonary Disease | May 2012 | August 2012 |
| NCT04252781 | Unknown status | N/A | Incident Chronic Obstructive pulmoNary dIsease Cohort Study (ICONIC) | February 2020 | February 2023 |
| NCT02499718 | Unknown status | N/A | Non-invasive Positive Pressure (NPPV ) for Severe Stable Chronic Obstructive Pulmonary Disease | January 2014 | December 2016 |
| NCT03010566 | Unknown status | Lung Volume Reduction Coil Microbiome Study | January 30, 2017 | January 2020 | |
| NCT02266316 | Unknown status | N/A | Use of an Air Warming Mask for Exercise in Patients With COPD V1.0 | March 2012 | July 2015 |
| NCT02143700 | Unknown status | Cognitive Status in Chronic Obstructive Pulmonary Disease's Patients | April 2014 | December 2014 | |
| NCT03988322 | Unknown status | N/A | Computed Tomography Screening for Early Lung Cancer, COPD and Cardiovascular Disease in Shanghai, China | September 1, 2018 | September 2022 |
| NCT02332122 | Unknown status | Detection of Aspergillus Fumigatus and Sensitization in COPD Patients With Bronchiectasis vs Without Bronchiectasis | January 2015 | May 2017 | |
| NCT05036057 | Unknown status | Turkish Version of the Individual Knowledge Statement Questionnaire of Chronic Obstructive Pulmonary Disease (COPD) | October 4, 2021 | October 4, 2022 | |
| NCT01173354 | Unknown status | N/A | EAA Intake to Optimize Protein Anabolism in COPD | January 2009 | June 2018 |
| NCT03923803 | Unknown status | Diagnostic Values of C-reactive Protein and Procalcitonin in Predicting Bacterial Infection in Acute Exacerbations of Chronic Obstructive Pulmonary Disease | July 2019 | October 2020 | |
| NCT01624792 | Unknown status | N/A | Eicosapentaenoic Acid and Protein Modulation to Induce Anabolism in Chronic Obstructive Pulmonary Disease (COPD): Aim 2 | October 2011 | April 2021 |
| NCT00317057 | Unknown status | N/A | Outpatient Management of Patients With Exacerbation of Chronic Obstructive Pulmonary Disease | April 2006 | January 2007 |
| NCT03802357 | Unknown status | N/A | Effects of Different Exercise Training Modalities in Alpha-1 Antitrypsin Deficiency Patients | January 10, 2019 | December 31, 2021 |
| NCT00186719 | Unknown status | How Smoking Causes COPD: Examination of Immune System Changes | May 2005 | April 2012 | |
| NCT02348151 | Unknown status | N/A | Shuttle Walk Test Performed on a Treadmill Versus a Corridor in Patients With COPD | January 2014 | June 2016 |
| NCT01131806 | Unknown status | Phase 4 | Comparing Treatment Efficacy With HD/MD Flu Plus Sal in Chronic Obstructive Pulmonary Disease (COPD) Patients | December 2009 | April 2011 |
| NCT01448564 | Unknown status | N/A | Effects of Laser Therapy on Muscle Function in COPD Patients | June 2012 | December 2013 |
| NCT01471587 | Unknown status | Fibre Specific Signalling in the Locomotor Myopathy of Chronic Obstructive Pulmonary Disease | December 2011 | October 2013 | |
| NCT01499433 | Unknown status | Phase 4 | Efficacy and Safety of Caspofungin for Invasive Pulmonary Aspergillosis Underlying Chronic Obstructive Pulmonary Disease | January 2012 | November 2014 |
| NCT03337854 | Unknown status | Analysis With Clusters of QUAntitative Tomodensitometric Vascular, bronchIal and Parenchymal Pulmonary Parameters for COPD Patients | December 20, 2017 | December 1, 2018 | |
| NCT00807469 | Unknown status | Responses Induced by Smoking in Individuals Being Susceptible and Non-Susceptible for Development of COPD | January 2009 | January 2015 | |
| NCT03449056 | Unknown status | Phase 3 | High-flow Nasal Cannula Nebulization of Beta 2 Adrenergic Agonist During Acute Exacerbation of Chronic Obstructive Pulmonary Disease | January 11, 2019 | April 2020 |
| NCT02218398 | Unknown status | N/A | Bronchodilator Test in Mechanical Ventilated Chronic Obstructive Pulmonary Disease Patients | May 2013 | December 2015 |
| NCT00857038 | Unknown status | Phase 4 | Doxycycline and Airway Inflammation in Chronic Obstructive Pulmonary Disease (COPD) | April 2009 | January 2010 |
| NCT04851093 | Unknown status | N/A | Effects of Traditional Chinese Medicine on Outcomes in Patients With AECOPD Risk Window | March 15, 2021 | December 31, 2022 |
| NCT01926275 | Unknown status | N/A | NPPV Added Inspiratory Muscle Training in Severe COPD | July 2013 | December 2013 |
| NCT01905982 | Unknown status | N/A | The Effect of Reflective Breathing Therapy Compared With Conventional Breathing Therapy in Patients With Chronic Obstructive Pulmonary Disease (COPD) III-IV; part2 | January 2016 | March 2020 |
| NCT04010084 | Unknown status | N/A | Photobiomodulation in Individuals With Chronic Obstructive Pulmonary Disease | August 1, 2019 | June 3, 2020 |
| NCT03467880 | Unknown status | Multicenter Study of Impulse Oscillometry in Chinese | September 2016 | December 2018 | |
| NCT03466385 | Unknown status | N/A | NHF vs NIV in Patients With Acute Exacerbation of COPD | April 15, 2018 | December 31, 2021 |
| NCT05211674 | Unknown status | Analysis of Postural Control of COPD Patients (ATTRACTION) | February 2022 | April 2023 | |
| NCT02823223 | Unknown status | N/A | Endobronchial Valve in Patients With Heterogeneous Emphysema | June 2016 | July 2018 |
| NCT01314807 | Unknown status | Systemic Consequences and Comorbidities in Mild/Moderate Chronic Obstructive Pulmonary Disease (COPD), Time for Action! | June 2009 | January 2018 | |
| NCT01990651 | Unknown status | Study of Use of CTC in NSCLC | September 2011 | ||
| NCT01452932 | Unknown status | Phase 1/Phase 2 | Muscle Training Effectiveness in the Degree of Dyspnea and Aerobic Capacity in COPD | June 2010 | December 2012 |
| NCT01155856 | Unknown status | N/A | The Virtual Hospital - a Clinical Trial | June 2010 | June 2013 |
| NCT02393469 | Unknown status | N/A | Effects of Pulmonary Rehabilitation on Respiratory, and Cardiovascular Functional Capacity in COPD | January 2014 | December 2016 |
| NCT01961245 | Unknown status | N/A | Effects of Nocturnal Non-invasive Ventilation on Energy Expenditure in Patients With Severe Chronic Obstructive Pulmonary Disease | December 2013 | December 2019 |
| NCT01397721 | Unknown status | Pulmonary Vascular Changes in Early Chronic Obstructive Pulmonary | May 2009 | July 2016 | |
| NCT01131390 | Unknown status | Phase 3 | Ventilator Settings and Comfort | March 2010 | December 2011 |
| NCT03081650 | Unknown status | N/A | The Efficacy of the AIRVO Warm Humidifier as an Add on to Oxygen Therapy | August 16, 2016 | December 1, 2017 |
| NCT01116063 | Unknown status | Phase 4 | Inhaled Iloprost for Disproportionate Pulmonary Hypertension in Chronic Obstructive Pulmonary Disease (COPD) | May 2010 | June 2013 |
| NCT02140892 | Unknown status | N/A | A Comparison Study of Two Respiratory Physical Therapy Methods and Standard Medical Treatment for Treating COPD Patients During Acute Exacerbation | July 2014 | December 2015 |
| NCT02941679 | Unknown status | Phase 3 | Clinical Efficacy and Safety Evaluation of HCP1202 in COPD Patients | October 2016 | April 2018 |
| NCT03382197 | Unknown status | N/A | Different Positive Pressure Strategies in COPD Patients. | January 1, 2018 | November 2018 |
| NCT04046640 | Unknown status | A Study on the Heat Transport Characteristics of Meridian Phenomenon for the Heart and Lung Meridians Based on Patients With Stable Angina Pectoris | February 2020 | December 2021 | |
| NCT04008017 | Unknown status | Eosinophilic Cationic Protein as a Biomarker in Diagnosis of Acute Exacerbation of Chronic Obstructive Pulmonary Disease | August 1, 2019 | December 2021 | |
| NCT01427673 | Unknown status | Phase 3 | Continuous Positive Airway Pressure Versus Noninvasive Ventilation in Patients With Overlap Syndrome | December 2011 | February 2014 |
| NCT03910985 | Unknown status | Phase 4 | Assessment of Reactance Parameters Measured by the Forced Oscillation Technique for the Bronchodilator Response in Subjects With Chronic Obstructive Pulmonary Disease (COPD) | April 23, 2019 | December 31, 2021 |
| NCT02433223 | Unknown status | Retrospective Evaluation of COPD Patient Care | June 2016 | June 2018 | |
| NCT00741832 | Unknown status | N/A | The Effects of a Positive Expiratory Pressure (PEP) on Dyspnea and Dynamic Hyperinflation During Exercise in Chronic Obstructive Pulmonary Disease (COPD) Patients | March 2008 | February 2009 |
| NCT01293890 | Unknown status | Adherence to Medication and Its Impact on Chronic Obstructive Pulmonary Disease (COPD) Exacerbations: The AMICE Prospective Study | March 2011 | ||
| NCT02282436 | Unknown status | Substudy : Patients With an Acute Exacerbation of Chronic Obstructive Pulmonary Disease | May 2012 | May 2018 | |
| NCT02824809 | Unknown status | Association Between Testosterone Levels and COPD Severity | June 2016 | March 2017 | |
| NCT00730301 | Unknown status | Phase 4 | EUROPT Clinical Trial to Study the Efficacy of One-Way Valve Implantation (New Treatment Algorithm) in Patients With Heterogeneous Emphysema | July 2007 | |
| NCT01599884 | Unknown status | N/A | N-Acetylcysteine for Patients With COPD and ChronicBronchitis | June 2012 | August 2013 |
| NCT04534062 | Unknown status | N/A | Effects of PNF D2 Technique With Resistance on Pulmonary Function, Exercise Capacity and Health Status of COPD Patients | October 1, 2020 | February 22, 2021 |
| NCT05069194 | Unknown status | Study on the Etiology, Risk Factors and Pathogenesis of COPD Based on Clinical Bioinformatics | December 10, 2017 | December 31, 2022 | |
| NCT01465906 | Unknown status | Phase 4 | Efficacy and Safety of Tulobuterol Patch Combined With Tiotropium Bromide for Relieving Dyspnea Symptom of Chronic Obstructive Pulmonary Disease | November 2010 | November 2011 |
| NCT02534402 | Unknown status | Phase 4 | Prednisone Administration in Quiescent COPD Patients to Determine the Effect on Gene Expression | August 2015 | December 2021 |
| NCT02397005 | Unknown status | Phase 1 | Study of the Tolerability and Pharmacokinetic of ZL-2102 With an Investigation of Food Effect in Healthy Male Subjects | March 2015 | August 2019 |
| NCT00948623 | Unknown status | N/A | Physical Activity Counseling During Pulmonary Rehabilitation | April 2009 | December 2011 |
| NCT03893409 | Unknown status | GIRH Chronic Obstructive Pulmonary Disease Observational Study | August 10, 2018 | December 30, 2022 | |
| NCT02550808 | Unknown status | Metabolic Changes in Patients With Chronic Cardiopulmonary Disease | March 2012 | December 2017 | |
| NCT04206098 | Unknown status | Chart Review of Patients With COPD, Using Electronic Medical Records and Artificial Intelligence | January 8, 2020 | December 30, 2020 | |
| NCT04225650 | Unknown status | Prevalence of Respiratory Impairment During IBD | May 1, 2020 | August 2020 | |
| NCT00920127 | Unknown status | Phase 2/Phase 3 | Treatment With AKL1 in Obstructive Airways Disease (The TAKL Study) | June 2009 | February 2012 |
| NCT02488590 | Unknown status | Systematic Approach for the Diagnosis and Treatment of Obstructive Lung Diseases | July 2015 | July 2021 | |
| NCT00850863 | Unknown status | Systemic Inflammation in Chronic Obstructive Pulmonary Disease (COPD) | February 2009 | January 2015 | |
| NCT00581087 | Unknown status | Phase 3 | Study of Dehydroepiandrosterone (DHEA) in Respiratory Pulmonary Hypertension in Adults | January 2007 | June 2015 |
| NCT04682899 | Unknown status | Phase 3 | A Trial of Procalcitonin in Patients With Acute Exacerbation of Chronic Obstructive Pulmonary Disease | February 1, 2021 | April 1, 2022 |
| NCT02235129 | Unknown status | N/A | Six Minute Walking Test and Breath-holding | September 2014 | December 2014 |
| NCT04045418 | Unknown status | A Study on the Microcirculatory Characteristics of Meridian Phenomenon for the Heart and Lung Meridians Based on Patients With COPD | February 2020 | December 2021 | |
| NCT04773860 | Unknown status | N/A | Muscle Energy Techniques in COPD Patients | February 23, 2021 | June 30, 2023 |
| NCT03258749 | Unknown status | N/A | Efficiency of Twice Daily Formoterol Versus Once Daily Tiotropium in Patients With GOLD A/B COPD | November 1, 2017 | October 31, 2018 |
| NCT03453606 | Unknown status | N/A | Respiratory Rehabilitation for Patients With Chronic Obstructive Pulmonary Disease | October 24, 2018 | January 2022 |
| NCT04834531 | Unknown status | Phase 4 | Effect of Zhuli Capsule on Phlegm-heat Syndrome (Tan-re Zheng) | July 2021 | October 2023 |
| NCT03327181 | Unknown status | N/A | Short Chain Fatty Acid Metabolism in COPD | April 19, 2017 | April 2022 |
| NCT02563184 | Unknown status | Phase 4 | Seasonal Influenza Vaccine, Quadrivalent Versus Trivalent in Patients With Advanced Chronic Obstructive Pulmonary Disease | September 2015 | February 2016 |
| NCT02018432 | Unknown status | Phase 4 | Strategy to Improve Adherence of Roflumilast | December 2013 | December 2015 |
| NCT02786030 | Unknown status | N/A | Integrated Primary Care for Chronic Lung Disease: PACK Brazil | April 1, 2017 | March 31, 2019 |
| NCT03337958 | Unknown status | N/A | Education With Inhalers in Patients With COPD Exacerbation | December 1, 2017 | July 2018 |
| NCT03177694 | Unknown status | A Wireless Bed Sensor for Monitoring Coughs | October 1, 2018 | May 2019 | |
| NCT04415827 | Unknown status | N/A | Energy Supply in Athletes and Untrained Persons With Bronchopulmonary Diseases | May 23, 2020 | December 1, 2022 |
| NCT01718067 | Unknown status | N/A | Efficacy of Vakum Technology in Patients With Chronic Hypersecretion | January 2013 | April 2016 |
| NCT03212001 | Unknown status | TeleHomecaRe InterVention Evaluation Study | July 2016 | October 2019 | |
| NCT04263961 | Unknown status | An Integrative Genomic Approach to Solve tHe Puzzle of sevERe earLy-Onset COPD | March 1, 2017 | August 2022 | |
| NCT03156673 | Unknown status | Early Phase 1 | Treatment of COPD by Autologous Transplantation of Bronchial Basal Cells | April 1, 2017 | June 30, 2022 |
| NCT01361984 | Unknown status | Phase 4 | Sunovion Brovana Versus Serevent Inspiratory Capacity High Resolution Computed Tomography | June 2011 | June 2013 |
| NCT02811588 | Unknown status | HomeVent ( Connect) Registry: EU COPD Home NIV Registry | July 2016 | June 2023 | |
| NCT02437630 | Unknown status | Intrinsic PEEP and Laryngeal Aperture in COPD | April 2016 | May 2018 | |
| NCT02219360 | Unknown status | Treatment in Patients Hospitalized With Acute Exacerbation of Chronic Obstructive Pulmonary Disease | August 2014 | September 2015 | |
| NCT00799305 | Unknown status | Correlation of Airflow Limitation and Other Respiratory Characteristics With Radiologic Changes of Lung Structure | January 2009 | ||
| NCT04784351 | Unknown status | Prediction of Expected Length of Hospital Stay Using Machine Learning | March 20, 2021 | December 1, 2021 | |
| NCT01626521 | Unknown status | Value of Prothrombin Fragment F1+2 in the Diagnosis of Pulmonary Embolism in Patients With Chronic Obstructive Pulmonary Disease (COPD) Exacerbation | July 2012 | January 2013 | |
| NCT04257630 | Unknown status | Coping Strategies Within Pulmonary Rehabilitation in Patients With IPF and COPD | February 6, 2020 | March 31, 2022 | |
| NCT03824834 | Unknown status | Phase 2 | Morphine to Maximize the Benefits of Exercise Training in COPD or ILD and Persistent Breathlessness | August 6, 2019 | November 2020 |
| NCT03813810 | Unknown status | Impact of Air Pollution on Chronic Respiratory Diseases | January 25, 2019 | December 2021 | |
| NCT04693975 | Unknown status | Social Distancing During the COVID-19 Pandemic and People Living With Chronic Respiratory Diseases | October 16, 2020 | October 2022 | |
| NCT02249455 | Unknown status | N/A | Effectiveness of Acapella and ELTGOL Technique to Promote Airway Clearance in COPD:a Comparative Study | July 2014 | January 2015 |
| NCT03531489 | Unknown status | N/A | Study of Ambulatory Respiratory Assist Device in Chronic Obstructive Pulmonary Disease Patients | April 26, 2018 | December 30, 2018 |
| NCT03480347 | Unknown status | The BLF Early COPD Development Partnership Grant | January 17, 2018 | April 30, 2023 | |
| NCT04208581 | Unknown status | Phase 3 | Yiqi Huoxue Huatan Granule for Reducing Mortality in COPD With Chronic Respiratory Failure | October 8, 2019 | December 2021 |
| NCT02398071 | Unknown status | N/A | The Effects of Positive Expiratory Pressure Breathing on The Rate of Post-exercise Recovery in Patients With COPD | August 2014 | March 2015 |
| NCT03473119 | Unknown status | Evaluation of Plasma Sphingosine-1-Phosphate as A Diagnostic and Prognostic Biomarkers of Community-Acquired Pneumonia | March 19, 2016 | March 19, 2021 | |
| NCT04898972 | Unknown status | N/A | Mindfulness-based Intervention in COPD Dyads | April 20, 2021 | December 30, 2023 |
| NCT03042039 | Unknown status | Multi-level Integration for Patients With Complex Needs Facilitated by ICTs. A Shared Approach, Mutual Learning and Evaluation Are Expected to Create Synergies Among the Partners and to Bring Forward Integration of Care in Europe | January 1, 2015 | October 1, 2017 | |
| NCT05086341 | Unknown status | N/A | A Pilot- and Feasibility Trial of the eHealth Tool My COPD for People With COPD | November 5, 2021 | May 1, 2023 |
| NCT04704479 | Unknown status | N/A | Russian Current and Expiratory Muscle Training in COPD Patients | March 15, 2021 | April 2022 |
| NCT02434198 | Unknown status | Falling in Patients With COPD Referred to Pulmonary Rehabilitation: Incidence, Risk Factors and Prediction Tools | January 2015 | ||
| NCT04473313 | Unknown status | Educational Follow-up in COPD Patients After Pulmonary Rehabilitation. | July 16, 2020 | August 16, 2022 | |
| NCT04121117 | Unknown status | Usefulness of the Chronic Obstructive Pulmonary Disease-population (COPD-PS) Questionnaire and the COPD-6 Device in the Chronic Obstructive Pulmonary Disease Detection in a Tobacco Detoxication Consultation | October 15, 2019 | June 15, 2020 | |
| NCT00706303 | Unknown status | N/A | Glasgow Supported Self Management Trial (GSuST) | June 2007 | December 2009 |
| NCT02790047 | Unknown status | N/A | Effect of Home-base Exercise With Conical-PEP Device on Physical Performance and Quality of Life in COPD | October 2016 | May 2018 |
| NCT00893685 | Unknown status | N/A | Randomized Controlled Trial of Home Telemonitoring for Elderly People | May 2009 | December 2011 |
| NCT00792974 | Unknown status | End-of-Life Fear in Patients With End-Stage Lung Disease (COPD) | October 2008 | July 2010 | |
| NCT00331656 | Unknown status | Phase 4 | Comparative Study of Non-Invasive Mask Ventilation vs Cuirass Ventilation in Patients With Acute Respiratory Failure. | June 2008 | December 2009 |
| NCT02832739 | Unknown status | N/A | Exploring Acceptance and Outcomes of an Online-based Self-management Support System in Chronic Illness | November 2016 | August 31, 2017 |
| NCT02259439 | Unknown status | Assessment of Updated Evaluation Scores in Critically ILL COPD Patients Admitted to Assiut University Hospital | September 2012 | December 2015 | |
| NCT01481727 | Unknown status | Phase 4 | Exacerbation Prevention GOLD IV COPD With Non Invasive Mechanical Ventilation | December 2011 | December 2015 |
| NCT04627935 | Unknown status | The Effect of Foot Deformities on Physical Activity, Fatigue Level and Quality of Life in Elderly COPD Patients | March 1, 2021 | December 30, 2021 | |
| NCT03264768 | Unknown status | N/A | Endoscopic Long Volume Reduction by Endobronchial Valves in Belgium | August 1, 2017 | December 2020 |
| NCT02037828 | Unknown status | Exhaled Breathing Condensate (EBC) Features and Lung Function Decline in Chinese Adults | June 2014 | December 2019 | |
| NCT02798003 | Unknown status | Food Reward in Cachexia Induced by Acute or Chronic Disease | November 2016 | September 2018 | |
| NCT04865861 | Unknown status | The Characteristic of Airway Microbiome Profiling of COPD-bronchiectasis Overlap Patients and Its Association With Acute Exacerbation | May 1, 2021 | June 30, 2023 | |
| NCT03976713 | Unknown status | Phase 3 | Bufei Yishen Granule for Reducing Acute Exacerbation in GOLD Stage 3 or 4 COPD | June 2019 | December 2020 |
| NCT00922545 | Unknown status | N/A | Evaluation of a Combined Strategy Addressed to Practitioners and Chronic Obstructive Pulmonary Disease (COPD) Patients to Improve Clinical Control and Quality of Life | April 2004 | December 2010 |
| NCT02903043 | Unknown status | Expression of miR-204 and Consequences on Capillarization in Limb Muscles of Patients With COPD | February 2013 | February 2018 | |
| NCT01513655 | Unknown status | Phase 4 | Home Non Invasive Ventilation (NIV) Treatment for COPD-patients After a NIV-treated Exacerbation | July 2013 | July 2020 |
| NCT03762330 | Unknown status | N/A | Structured Comprehensive Intervention to Stimulate Self- Management and Improve Quality of Life in COPD Patients | January 19, 2019 | January 2021 |
| NCT04046588 | Unknown status | N/A | The Difference in Heat Transport Characteristics of the Heart and Lung Meridians | October 1, 2019 | December 2021 |
| NCT00925171 | Unknown status | Phase 2 | Maintenance Schedules Following Pulmonary Rehabilitation | June 2009 | June 2012 |
| NCT03940040 | Unknown status | N/A | High Flow Nasal Oxygen Versus Usual Care in COPD Pulmonary Rehabiliation | May 28, 2019 | June 2021 |
| NCT05007574 | Unknown status | A Microphone for Monitoring Coughs | October 1, 2021 | February 1, 2022 | |
| NCT03183817 | Unknown status | N/A | Person-centred Care at Distance | August 17, 2017 | June 30, 2021 |
| NCT04204031 | Unknown status | N/A | Objective Evaluation of the Number of Use Hour of Oxygen Therapy in Patients Receiving Supplemental Oxygen | January 2, 2020 | September 30, 2020 |
| NCT03942302 | Unknown status | Characterization of Variable MARrcha's Diary Variables as a Useful Measure | March 1, 2019 | April 1, 2020 | |
| NCT01295359 | Unknown status | N/A | Impact of a Hospital Physical Therapy Program on Chronic Obstructive Pulmonary Disease (COPD) Patients | March 2011 | August 2012 |
| NCT04459156 | Unknown status | N/A | Fiber Metabolism in Chronic Obstructive Pulmonary Disease | June 23, 2020 | December 2023 |
| NCT03084874 | Unknown status | N/A | Efficacy of a Coaching Program to Promote Physical Activity and Reduce Sedentary Behavior After a COPD Hospitalization | March 2017 | December 2018 |
| NCT03601403 | Unknown status | N/A | Tablet-assisted Training in Exacerbated COPD | December 1, 2017 | April 2019 |
| NCT01074515 | Unknown status | Chronic Obstructive Pulmonary Disease (COPD) Activity: Serotonin Transporter (SERT), Cytokines and Depression (CASCADE Study) | February 2010 | February 2016 | |
| NCT03432026 | Unknown status | Phenotypes of COPD | April 1, 2019 | April 1, 2021 | |
| NCT02392715 | Unknown status | N/A | Inspiratory Muscle Training Combined With General Exercise Training in COPD | April 2015 | December 2016 |
| NCT02521636 | Unknown status | N/A | Clinical Trial Assessing the Value of an Antibiotic Protocol Guided by Serum Procalcitonin in Acute Exacerbations of Chronic Obstructive Pulmonary Disease in Intensive Care | October 2010 | |
| NCT04117399 | Unknown status | N/A | Effect of Inspiratory Muscle Training on Posture in Chronic Obstructive Pulmonary Disease Patients | February 1, 2019 | November 15, 2019 |
| NCT03227523 | Unknown status | Nonspecific Low Back Pain in Association With Chronic Obstructive Pulmonary Disease | June 1, 2017 | May 31, 2018 | |
| NCT02826265 | Unknown status | Evaluation of Novel Lung Function Parameters and Quantitative Computed Tomography (qCT) in Patients With Pulmonary Disease | January 2016 | December 2020 | |
| NCT01510041 | Unknown status | N/A | Effects of Respiratory Muscle Training and Respiratory Exercise in Exercise Tolerance, Performing Daily Life Activities and Quality of Life of Patients With Chronic Obstructive Pulmonary Disease | January 2011 | February 2013 |
| NCT01560741 | Unknown status | Phase 1 | Telemedicine and Ventilator Titration in Chronic Respiratory Patients Initiating Non-invasive Ventilation | July 2012 | May 2013 |
| NCT02284932 | Unknown status | Muscle Atrophy In Patients With Chronic Obstructive Pulmonary Disease | September 2011 | September 2018 | |
| NCT00920348 | Unknown status | The Canadian Cohort Obstructive Lung Disease | January 2010 | December 2022 | |
| NCT03641235 | Unknown status | Analysis of the Dynamics of the Lung Microbiota During Acute Exacerbation of COPD Requiring Admission to Intensive Care Unit | September 1, 2018 | September 1, 2020 | |
| NCT04664491 | Unknown status | N/A | Effects of COPD Standardized Management on COPD Exacerbation | February 1, 2021 | December 31, 2022 |
| NCT04238221 | Unknown status | Phase 4 | Effect of add-on Doxofylline on Lung Function in Stable COPD | September 1, 2020 | November 30, 2020 |
| NCT03863717 | Unknown status | N/A | Investigation of the Effectiveness of Upper Limb Exercise in COPD Patients | December 14, 2017 | May 31, 2020 |
| NCT02086383 | Unknown status | Physical Activity and Self-Efficacy After Pulmonary Rehabilitation | April 2014 | August 2014 | |
| NCT04994574 | Unknown status | N/A | Effects of Tiotropium/Olodaterol on Cardio-pulmonary Exercise Capacity in Patients With Hyperinflated Chronic Obstructive Pulmonary Disease [ACHIEVE] | August 2021 | November 2022 |
| NCT04011930 | Unknown status | Phase 2 | This Study Include Chronic Obstructive Pulmonary Disease(COPD) Patients . Patients Were Vitamin D Deficient Age Range 40 to 80 Years, Smokers Patients Were Advised to Take Either Placebo or Vitamin D3 . Antioxidant Enzymes Were Assessed at Baseline and at 26th Weeks. | March 1, 2019 | February 28, 2020 |
| NCT00871962 | Unknown status | Long-term Oxygen Treatment (LTOT) in Chronic Obstructive Pulmonary Disease: Factors Influencing Survival | June 2009 | May 2016 | |
| NCT03577002 | Unknown status | N/A | Team-based Versus Primary Care Clinician-led Advance Care Planning in Practice-based Research Networks | February 28, 2019 | July 1, 2023 |
| NCT04348344 | Unknown status | N/A | Study on the Prevention and Control System of Chronic Airway Diseases | June 1, 2020 | September 1, 2021 |
| NCT00238836 | Unknown status | Phase 2/Phase 3 | Anticipatory & Preventive Team Care (APTCare): At Risk Patients of Family Health Networks | March 2006 | |
| NCT03956888 | Unknown status | Phase 3 | The Anti-oxidant Effects of N-Acetylcysteine in Chronic Obstructive Pulmonary Disease (COPD) | June 1, 2019 | May 1, 2020 |
| NCT04866550 | Unknown status | Health in Smart Rurality: Impact on Coordination of Care of Telemonitoring and Data Centralization of Frailty Patients | June 25, 2021 | August 1, 2022 | |
| NCT05051930 | Unknown status | Phase 1 | A Clinical Trial of TQC3721 Suspension for Inhalation | October 18, 2021 | December 31, 2022 |
| NCT04520568 | Unknown status | Phase 2 | High Flow Nasal Cannula Oxygen During Sedation for Video-assisted Thoracoscopic Surgery | August 1, 2020 | December 1, 2020 |
| NCT04876833 | Unknown status | Characteristics of Intestinal Microbiome in the Progression of Early COPD | May 2021 | July 2022 | |
| NCT00555529 | Withdrawn | Systemic Endothelial Abnormalities in COPD | January 2006 | November 2008 | |
| NCT02107222 | Withdrawn | N/A | The PALP™-COPD Trial (Low-Flow CO2-Removal (ECCO2-R) in Exacerbated COPD) | ||
| NCT03653104 | Withdrawn | N/A | Melodica Orchestra for Dyspnea: Safety and Feasibility Pilot | June 12, 2018 | December 31, 2019 |
| NCT00741767 | Withdrawn | N/A | The Impact of Salmeterol-Fluticasone on Sleep in Patients With COPD | August 2008 | February 2012 |
| NCT01176318 | Withdrawn | Phase 4 | Erdosteine (Erdotin) Versus Standard Care Plus Placebo on Erdosteine for Treatment of Cough in Acute Exacerbations of Chronic Obstructive Pulmonary Disease (COPD) | August 10, 2010 | January 13, 2012 |
| NCT02050256 | Withdrawn | N/A | Improving End-of-life Care by Continuing Medical Education and Electronic Decision Making Support for General Practitioners | February 2014 | December 2014 |
| NCT04066751 | Withdrawn | Phase 2 | The Multicenter Topic Trial | December 1, 2021 | October 31, 2024 |
| NCT00288964 | Withdrawn | Phase 3 | Use of the Hattler Respiratory Assist Catheter in Severe Respiratory Failure | November 2005 | |
| NCT04419428 | Withdrawn | A40 Expiratory Flow Limitation Registry | February 2024 | September 2025 | |
| NCT01834885 | Withdrawn | Phase 3 | A 12 Week Study of QVA149 Compared to Fluticasone/Salmeterol (Advair) for Treatment of COPD | December 2013 | September 2014 |
| NCT01757015 | Withdrawn | Phase 3 | Safety and Efficacy of NVA237 as an add-on to Fixed Dose Combination LABA/ICS | April 2013 | April 2014 |
| NCT02455362 | Withdrawn | Phase 3 | Opioids for Refractory Breathlessness in Chronic Obstructive Pulmonary Disease | May 2015 | April 2018 |
| NCT03323190 | Withdrawn | N/A | An Educational Intervention to Improve Disease Management Knowledge of Hospitalized Patients With COPD | August 30, 2016 | August 30, 2017 |
| NCT01505556 | Withdrawn | Proprioceptive Postural Control and Diaphragm Paresis | January 2014 | January 2015 | |
| NCT00298402 | Withdrawn | Macrophages in Smokers' Lung | October 2005 | October 2007 | |
| NCT02775487 | Withdrawn | Smog Induced Indoor Air Pollution in Homes of Chronic Obstructive Pulmonary Disease Patients. | January 2013 | January 2013 | |
| NCT01393145 | Withdrawn | Phase 3 | Efficacy and Safety Study of Formoterol/Fluticasone and Salmeterol/Fluticasone in Patients With Moderate-to-severe COPD | August 2011 | August 2012 |
| NCT00972868 | Withdrawn | N/A | A Novel Unidirectional Face Mask During NPPV in COPD Patients | March 2011 | June 2013 |
| NCT01120574 | Withdrawn | N/A | Home Mechanical Ventilation in Patients With Chronic Obstructive Pulmonary Disease (COPD) and Hypercapnic Response | October 2005 | December 2015 |
| NCT00335621 | Withdrawn | Phase 4 | Replacement of Nebulised Ipratropium With Inhaled Tiotropium in Stable Chronic Obstructive Pulmonary Disease (COPD) | June 2006 | December 2007 |
| NCT04361552 | Withdrawn | Phase 3 | Tocilizumab for the Treatment of Cytokine Release Syndrome in Patients With COVID-19 (SARS-CoV-2 Infection) | April 7, 2020 | June 2, 2020 |
| NCT04042168 | Withdrawn | Phase 4 | Implications of Appropriate Use of Inhalers in Chronic Obstructive Pulmonary Disease (COPD) | September 25, 2019 | August 9, 2022 |
| NCT02406534 | Withdrawn | A Prospective, Observational Study of COPD Patients in U.S. Hospitals | |||
| NCT01559051 | Withdrawn | Phase 1/Phase 2 | Safety and Efficacy of Adipose Derived Stem Cells for Chronic Obstructive Pulmonary Disease | March 2014 | December 2017 |
| NCT03012646 | Withdrawn | Phase 2 | Safety and Tolerability of Inhaled Treprostinil in Adult PH Due to COPD | April 2017 | April 2019 |
| NCT00159289 | Withdrawn | N/A | Endotoxin and Inflammatory Markers in Healthy Non-Smokers and Current Smokers Including Patients With Chronic Obstructive Pulmonary Disease (COPD) | June 2003 | June 2003 |
| NCT04087369 | Withdrawn | N/A | Integrated NCD Intervention in Rural Nepal | December 1, 2019 | December 2023 |
| NCT00579046 | Withdrawn | Phase 3 | Study of Erythropoietin to Treat Anemia Complicating Chronic Obstructive Pulmonary Disease | November 2008 | October 2009 |
| NCT00789100 | Withdrawn | Evaluation of Remote Patient Monitoring. | February 2009 | February 2011 | |
| NCT00826566 | Withdrawn | N/A | Anti-inflammatory Effects of Caffeine in Chronic Obstructive Pulmonary Disease (COPD) Subjects | January 2009 | September 2009 |
| NCT02021747 | Withdrawn | Biologic Basis Of Increased Susceptibility Of Smokers To Pulmonary Infection With Mycobacterium Tuberculosis | January 2014 | October 2016 | |
| NCT00382447 | Withdrawn | N/A | Breath Actuated Nebulizer Study Protocol | October 2006 | June 2008 |
| NCT04440488 | Withdrawn | Phase 4 | ARALAST NP Alpha-1 Lung Density Chronic Obstructive Pulmonary Disease-Emphysema (COPD-E) Study | March 8, 2021 | September 12, 2025 |
| NCT04088942 | Withdrawn | Phase 4 | TOBacco STOP in Chronic Obstructive Pulmonary Disease-Trial - Study Protocol | July 1, 2023 | January 1, 2026 |
| NCT02030145 | Withdrawn | N/A | Thoracic Lymphatic Pump Techniques for Reducing Lung Volumes in Persons With Chronic Obstructive Pulmonary Disease | February 2007 | February 2008 |
| NCT03051971 | Withdrawn | N/A | Medicated Aerosol Delivery Using A Jet Nebulizer Versus A Vibrating Mesh Nebulizer in COPD Exacerbation | March 2017 | April 2018 |
| NCT01860066 | Withdrawn | Phase 3 | A 12 Week Study of QVA149 Compared to Fluticasone/Salmeterol (Advair) for Treatment of COPD | December 2013 | September 2014 |
| NCT05411107 | Withdrawn | Phase 2 | Oral Iloprost for the Prevention of Lung Cancer In Former Smokers | June 1, 2024 | June 30, 2027 |
| NCT00633776 | Withdrawn | Phase 4 | Perforomist Versus Foradil Evaluated by Inspiratory Capacity and High Resolution Computed Tomography (HRCT) | March 2008 | January 2009 |
| NCT05984680 | Withdrawn | N/A | COPD Care Pathway Among Patients With Cancer | March 2024 | August 2025 |
| NCT00159237 | Withdrawn | GR Defect in Peripheral Blood Mononuclear Cells in COPD | February 2005 | December 2008 | |
| NCT02041000 | Withdrawn | N/A | Adipose Derived Cells for Chronic Obstructive Pulmonary Disease | January 2014 | |
| NCT02203474 | Withdrawn | Phase 2 | A Study of 3 Doses of Tiotropium Hydrofluoralkane (HFA) Breath Actuated Inhaler (BAI), in Patients With Chronic Obstructive Pulmonary Disease | August 2014 | August 2014 |
| NCT04446637 | Withdrawn | Phase 3 | Acute Bronchodilator Effects of Ipratropium/Levosalbutamol 20/50 mcg Fixed Dose Combination vs Salbutamol 100 mcg Inhaler Plus Ipratropium 20 mcg Inhalation Aerosol Free Combination in Patients With Stable COPD | September 3, 2021 | September 3, 2022 |
| NCT03081247 | Withdrawn | Phase 3 | To Assess the Efficacy and Safety of PT010 Compared to PT009 in Subjects With Moderate to Very Severe Chronic Obstructive Pulmonary Disease | April 16, 2018 | December 7, 2018 |
| NCT03489746 | Withdrawn | N/A | Steroid Withdrawal Intervention in Fife and Tayside | May 1, 2018 | December 2022 |
| NCT02884830 | Withdrawn | N/A | Nocturnal Continuous Positive Airway Pressure in Chronic Obstructive Pulmonary Disease Patients | January 7, 2019 | December 31, 2019 |
| NCT03181880 | Withdrawn | Phase 4 | To Evaluate Effectiveness of Aclidinium Bromide/Formoterol Fumarate Dihydrate in Chronic Obstructive Pulmonary Disease | December 4, 2017 | December 3, 2018 |
| NCT05009485 | Withdrawn | N/A | A Pre-post Intervention Study Evaluating Home-based Management of Patients With COPD or CAP | January 1, 2022 | May 1, 2024 |
| NCT03385317 | Withdrawn | N/A | Mindfulness to Mitigate the Effect of Anxiety-depression-fear in Chronic Obstructive Pulmonary Disease (COPD) | April 2016 | October 31, 2017 |
| NCT00914433 | Withdrawn | Phase 1 | Safety, Tolerability, Pharmacodynamics and Pharmacokinetics of Inhaled TPI 1100 in Healthy Volunteers | April 2009 | April 2010 |
| NCT01174316 | Withdrawn | N/A | Autotitrating Versus Standard Non-invasive Ventilation (NIV) in Acute Exacerbation of Respiratory Failure | August 2010 | May 10, 2011 |
| NCT00446121 | Withdrawn | Inhaled Mannitol and Ciliary Beat Frequency in COPD Patients | January 2010 | January 2012 |
- Disase is a (Disease Ontology)
- DOID:2320
- Cross Reference ID (Disease Ontology)
- EFO:0000341
- Cross Reference ID (Disease Ontology)
- ICD10CM:J44.9
- Cross Reference ID (Disease Ontology)
- MESH:D029424
- Cross Reference ID (Disease Ontology)
- MIM:606963
- Cross Reference ID (Disease Ontology)
- NCI:C3199
- Cross Reference ID (Disease Ontology)
- SNOMEDCT_US_2023_03_01:13645005
- Cross Reference ID (Disease Ontology)
- UMLS_CUI:C0024117
- Exact Synonym (Disease Ontology)
- chronic obstructive airway disease
- Exact Synonym (Disease Ontology)
- chronic obstructive lung disease
- Exact Synonym (Disease Ontology)
- COLD
- Exact Synonym (Disease Ontology)
- COPD
- HPO Human Phenotype ID (Human Phenotype Ontology)
- HP:0006510