pigmented villonodular synovitis

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Information
Disease name
pigmented villonodular synovitis
Disease ID
DOID:2702
Description
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
Genes Mutation Description Source Links
NCT ID Status Phase Summary Start date Completion date
NCT05804045 Active, not recruiting Phase 3 Study of Pimicotinib (ABSK021) for Tenosynovial Giant Cell Tumor (MANEUVER) April 27, 2023 June 2028
NCT03069469 Active, not recruiting Phase 1/Phase 2 Study of Vimseltinib (DCC-3014) in Patients With Advanced Tumors and Tenosynovial Giant Cell Tumor February 16, 2017 August 2028
NCT04731675 Active, not recruiting Phase 2 An Open-Label Study of Intra-articular AMB-05X Injections in Subjects With Tenosynovial Giant Cell Tumor of the Knee May 25, 2021 October 31, 2022
NCT05059262 Active, not recruiting Phase 3 Study of Vimseltinib for Tenosynovial Giant Cell Tumor October 14, 2021 July 2026
NCT01207492 Active, not recruiting Phase 2 Nilotinib in Patients With Relapsed or Metastatic Pigmented Villonodular Synovitis/Tenosynovial Giant Cell Tumor/Diffuse-Type Giant Cell Tumor September 2010 January 2025
NCT02471716 Completed Phase 1/Phase 2 Study of Cabiralizumab in Patients With Pigmented Villonodular Synovitis / Diffuse Type Tenosynovial Giant Cell Tumor June 2015 April 30, 2020
NCT02371369 Completed Phase 3 Phase 3 Study of Pexidartinib for Pigmented Villonodular Synovitis (PVNS) or Giant Cell Tumor of the Tendon Sheath (GCT-TS) May 11, 2015 April 30, 2021
NCT04955535 Completed Screening of Specific Genes for Pigmented Villous Nodular Synovitis August 3, 2020 December 27, 2020
NCT04952896 Completed Clinical Study of Magnetic Resonance Imaging and Deep Learning of Joint Synovial Disease January 1, 2012 October 29, 2022
NCT01261429 Completed Phase 2 Study of Nilotinib Efficacy in Pigmented Villo-Nodular Synovitis/ Tenosynovial Giant Cell Tumour (PVNS/TGCT) December 2010 April 2013
NCT01643850 Completed Phase 2 MCS110 in Patients With Pigmented Villonodular Synovitis (PVNS) April 23, 2012 December 21, 2018
NCT05349643 Recruiting Phase 2 A Study to Evaluate Safety and Efficacy of AMB-05X Injections in Subjects With TGCT January 26, 2023 January 2026
NCT04938180 Terminated Phase 2 A Phase 2 Study of Intravenous AMB-05X in Tenosynovial Giant Cell Tumor Patients September 16, 2021 May 17, 2022
Disase is a (Disease Ontology)
DOID:2703
Cross Reference ID (Disease Ontology)
GARD:7396
Cross Reference ID (Disease Ontology)
ICD10CM:M12.2
Cross Reference ID (Disease Ontology)
MESH:D013586
Cross Reference ID (Disease Ontology)
NCI:C3401
Cross Reference ID (Disease Ontology)
SNOMEDCT_US_2023_03_01:202903009
Cross Reference ID (Disease Ontology)
UMLS_CUI:C0039106
Exact Synonym (Disease Ontology)
Diffuse Giant cell tumor of Tenosynovium
Exact Synonym (Disease Ontology)
villous tenosynovitis
OrphaNumber from OrphaNet (Orphanet)
66627