focal epilepsy
Information
- Disease name
- focal epilepsy
- Disease ID
- DOID:2234
- Description
- "An epilepsy syndrome that is characterized by seizures that are preceded by an isolated disturbance of a cerebral function and arise from an epileptic focus, a small portion of the brain that serves as the irritant driving the epileptic response." [url:http\://en.wikipedia.org/wiki/Epilepsy, url:http\://en.wikipedia.org/wiki/Focal_epilepsy, url:http\://www.aafp.org/afp/2001/0701/p91.html]
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
| Genes | Mutation | Description | Source | Links |
|---|
| NCT ID | Status | Phase | Summary | Start date | Completion date |
|---|---|---|---|---|---|
| NCT03796962 | Active, not recruiting | Phase 2 | A Study to Evaluate XEN1101 as Adjunctive Therapy in Focal Epilepsy | January 30, 2019 | October 2028 |
| NCT05497193 | Active, not recruiting | Clinical Efficacy and Safety of Perampanel Monotherapy in the Treatment of Children With Focal Epilepsy | July 1, 2021 | October 20, 2023 | |
| NCT01311440 | Completed | N/A | Modified Atkins Diet Treatment for Adults With Drug-resistant Epilepsy | March 2011 | July 2017 |
| NCT00438451 | Completed | Phase 4 | Study on the Treatment of Elderly Patients With Older and Newer Antiepileptic Drugs | January 2007 | August 2011 |
| NCT01772654 | Completed | N/A | Arterial Spin Labeling MRI Focal Abnormalities in Refractory Epilepsy | January 2013 | November 2013 |
| NCT02126774 | Completed | The Human Epilepsy Project | July 2012 | July 1, 2021 | |
| NCT03607851 | Completed | Phase 4 | Efficacy and Safety of Rapid Titration Protocols of Lacosamide | August 3, 2018 | June 7, 2019 |
| NCT02898935 | Completed | Improvement of the Accuracy of Spatial Representation of Invasive Exploratory Electrodes in Focal Epilepsy | November 25, 2016 | July 2018 | |
| NCT03082222 | Completed | ZEDEBAC: Zebinix Effects in Dependency of Baseline Conditions | July 2015 | October 29, 2018 | |
| NCT02208492 | Completed | Phase 4 | The Effects on Cognitive Function of Levetiracetam (Keppra®) Compared to Carbamazepine (Tegretol®, Carmazepine®) as Monotherapy for Children With Partial Seizure; A Multicentric Randomized Controlled Study | September 2011 | February 2014 |
| NCT00855738 | Completed | Phase 4 | A Prospective, Observational Study On The Effectiveness Of New Antiepileptic Drugs As First Bitherapy In The Daily Clinical Practice | May 2007 | June 2009 |
| NCT05718817 | Enrolling by invitation | Phase 3 | An Open-label Study of XEN1101 in Epilepsy | April 25, 2023 | September 2028 |
| NCT05748236 | Enrolling by invitation | Phase 4 | The Efficacy and Safety of Lamotrigine Versus Carbamazepine in Focal Epilepsy | November 1, 2022 | October 2023 |
| NCT06453759 | Not yet recruiting | N/A | Thalamic Recordings in Children Undergoing SEEG | August 2024 | December 2027 |
| NCT04653012 | Not yet recruiting | N/A | Multi-level Approach of Brain Activity Using Intracranial Electrodes in Epileptic Patients | December 1, 2020 | December 1, 2030 |
| NCT04998123 | Not yet recruiting | N/A | Efficacy of Intersectional Short Pulse Stimulation for Terminating Seizures | January 2025 | December 2026 |
| NCT05635396 | Not yet recruiting | N/A | Seizures Detection in Real Life Setting | December 15, 2022 | March 15, 2023 |
| NCT06205160 | Not yet recruiting | N/A | Evaluation of New Flexible High-density Intra-operative ECoG Electrodes for Epilepsy Surgery. ( EpiGrid ) | April 2024 | July 2025 |
| NCT06210022 | Not yet recruiting | Cognitive Impairment in Drug-resistant and Drug-responsive Focal Cryptogenic Epilepsy | March 2024 | March 1, 2027 | |
| NCT06366009 | Not yet recruiting | Assessment of Patients With Drug-resistant Temporal Lobe Epilepsy With EEG Extended With Intra-auricular Electrodes | April 8, 2024 | July 31, 2024 | |
| NCT06443463 | Not yet recruiting | Phase 2 | Long-term Safety and Tolerability of BHV-7000 | July 2024 | January 2027 |
| NCT04839601 | Recruiting | N/A | RNS System RESPONSE Study | October 27, 2021 | December 31, 2027 |
| NCT04986683 | Recruiting | N/A | Diffusion MRI Methods to Minimize Postoperative Deficits in Pediatric Epilepsy Surgery | August 1, 2021 | June 30, 2026 |
| NCT06309966 | Recruiting | Phase 2/Phase 3 | Study to Determine if BHV-7000 is Effective and Safe in Adults With Refractory Focal Onset Epilepsy | May 13, 2024 | September 2025 |
| NCT05100771 | Recruiting | Optimized Volumetry in Radiology: Interest in Pediatric Brain MRI in the Exploration of Focal Epilepsy | March 14, 2022 | March 2025 | |
| NCT05198882 | Recruiting | Phase 1 | Clinical Evaluation of Interstitial Laser Thermal Therapy Under Continuous MRI Monitoring as a Minimally Invasive Treatment of Patients With Medically Unbalanced Partial Epilepsy | July 4, 2022 | August 15, 2024 |
| NCT05278221 | Recruiting | N/A | TMS Combined With EEG/EMG as a Biomarker Predicting Antiepileptic Drug Response | August 1, 2022 | March 31, 2024 |
| NCT05673915 | Recruiting | N/A | Study of Transcranial Direct Current Stimulation to Treat Epilepsy | April 12, 2023 | February 2025 |
| NCT05981755 | Recruiting | N/A | Breathing Rescue for SUDEP Prevention | July 31, 2023 | June 30, 2028 |
| NCT03644732 | Recruiting | Atlas of Human Cognition by SEEG (MAPCOG-SEEG) | April 5, 2018 | September 2030 | |
| NCT06132893 | Recruiting | Phase 2/Phase 3 | A Study to Determine if BHV-7000 is Effective and Safe in Adults With Refractory Focal Onset Epilepsy | March 14, 2024 | September 2025 |
| NCT04879433 | Recruiting | Prospective Open-label Evaluation of Cenobamate Adjunctive Treatment of Adults With Refractory Focal Epilepsy | June 25, 2020 | November 30, 2023 | |
| NCT04529954 | Terminated | Phase 1/Phase 2 | Anti-Epilepsy Medication Valproate Administered Via ICV Route and Catheters and Pumps for CSF Infusion | January 1, 2021 | March 1, 2024 |
| NCT03955432 | Terminated | N/A | Long-term Cardiac Monitoring in Epilepsy | March 19, 2019 | January 3, 2023 |
| NCT01724918 | Terminated | Phase 2 | Lacosamide IV and EEG/EKG (LIVE) Study | May 2013 | August 2016 |
| NCT05081518 | Terminated | Phase 1 | A Study of Lu AG06466 in Participants With Treatment Resistant Focal Epilepsy | September 29, 2021 | April 14, 2022 |
| NCT03457961 | Unknown status | Post-market Study of AMPA Receptor Antagonists for Epilepsy Patients in Hong Kong | July 23, 2016 | July 1, 2021 | |
| NCT03321240 | Unknown status | Study of Predictive Biomarkers for Rational Management of Drug-resistant Epilepsy Associated With Focal Cortical Dysplasia | January 15, 2018 | December 15, 2022 | |
| NCT05180916 | Unknown status | N/A | Priming the Epileptic Brain: tVNS to Improve Efficacy of add-on AED in Patients With Focal Epilepsy | August 1, 2021 | July 1, 2023 |
| NCT03278210 | Unknown status | National Study on the Interest of EEG-fMRI in the Presurgical Evaluation of Partial Epilepsies Drug | April 13, 2011 | April 2020 | |
| NCT02245061 | Unknown status | N/A | Cortical Excitability Assessment Using Paired Pulses | September 9, 2014 | September 30, 2021 |
| NCT03916848 | Unknown status | N/A | Novel Network Analysis of Intracranial Stereoelectroencephalography | June 16, 2019 | April 2022 |
| NCT05481905 | Withdrawn | Phase 2 | ENACT: A Study of ENX-101 as Adjunctive Treatment in Patients With Focal Seizures | September 2022 | December 2024 |
- Disase is a (Disease Ontology)
- DOID:1826
- Cross Reference ID (Disease Ontology)
- MESH:D004828
- Cross Reference ID (Disease Ontology)
- NCI:C122812
- Cross Reference ID (Disease Ontology)
- SNOMEDCT_US_2023_03_01:230381009
- Cross Reference ID (Disease Ontology)
- UMLS_CUI:C0014547
- Exact Synonym (Disease Ontology)
- localisation-related epilepsy
- Exact Synonym (Disease Ontology)
- partial epilepsy