factor VII deficiency
Information
- Disease name
- factor VII deficiency
- Disease ID
- DOID:2215
- Description
- "A blood coagulation disease that is characterized by easy bleeding, has_symptom epistaxis, bleeding of the gums, menorrhagia, and occasionally hemarthrosis, and has_material_basis_in autosomal recessive inheritance of mutation in the F7 gene, which encodes coagulation factor VII, an important factor in the clotting cascade." [url:http\://omim.org/entry/227500, url:https\://ghr.nlm.nih.gov/condition/factor-vii-deficiency#genes]
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
| Genes | Mutation | Description | Source | Links |
|---|
| NCT ID | Status | Phase | Summary | Start date | Completion date |
|---|---|---|---|---|---|
| NCT01269138 | Completed | Treatment of Inherited Factor VII Deficiency | January 2007 | November 2012 | |
| NCT03079063 | Completed | Phase 3 | Study Comparing the Pharmacokinetic of Biosimilar Eptacog Alfa With Novoseven®, in Patients With Congenital Factor VII Deficiency | March 1, 2017 | January 28, 2021 |
| NCT03372993 | Completed | Prospective, Non-interventional Study to Evaluate Immunogenicity of AryoSeven | June 13, 2016 | April 15, 2021 | |
| NCT05651061 | Completed | Phase 1 | A Phase I of SS109 in Hemophilia A or and B With Inhibitors | December 14, 2022 | August 15, 2023 |
| NCT03655223 | Enrolling by invitation | Early Check: Expanded Screening in Newborns | October 15, 2018 | December 31, 2025 | |
| NCT04548791 | Terminated | Phase 1/Phase 2 | Study of Coagulation Factor VIIa Marzeptacog Alfa (Activated) in Subjects With Inherited Bleeding Disorders | May 17, 2021 | December 3, 2021 |
- Disase is a (Disease Ontology)
- DOID:1247
- Cross Reference ID (Disease Ontology)
- GARD:2238
- Cross Reference ID (Disease Ontology)
- ICD10CM:D68.2
- Cross Reference ID (Disease Ontology)
- MESH:D005168
- Cross Reference ID (Disease Ontology)
- MIM:227500
- Cross Reference ID (Disease Ontology)
- NCI:C131631
- Cross Reference ID (Disease Ontology)
- ORDO:327
- Cross Reference ID (Disease Ontology)
- SNOMEDCT_US_2023_03_01:154820003
- Cross Reference ID (Disease Ontology)
- UMLS_CUI:C0015503
- Exact Synonym (Disease Ontology)
- deficiency, stable
- MeSH unique ID (MeSH (Medical Subject Headings))
- D005168