neuroendocrine tumor (Cancer)

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Information
Disease name
neuroendocrine tumor
Disease ID
DOID:169
Description
"An endocrine gland cancer that has_material_basis_in neuroendocrine cells." [url:http\://en.wikipedia.org/wiki/Neuroendocrine_cell, url:http\://en.wikipedia.org/wiki/Neuroendocrine_tumor, url:http\://www.cancer.gov/dictionary?CdrID=44904]
Disease area statistics
Chromosome band
Gene symbol Chromosome Start Stop The number of variant
RET 10 43,077,069 43,130,351 2
TP53 17 7,668,421 7,687,490 2
APC 5 112,737,885 112,846,239 2
EGFR 7 55,019,017 55,211,628 2
Annotation
Genes Mutation Description Source Links
NCT ID Status Phase Summary Start date Completion date
NCT00569127 Active, not recruiting Phase 3 Octreotide Acetate and Recombinant Interferon Alfa-2b or Bevacizumab in Treating Patients With Metastatic or Locally Advanced, High-Risk Neuroendocrine Tumor December 1, 2007 January 31, 2025
NCT03012789 Active, not recruiting N/A Surgical Intervention and the NETest May 15, 2017 June 2026
NCT04400474 Active, not recruiting Phase 2 Trial of Cabozantinib Plus Atezolizumab in Advanced and Progressive Neoplasms of the Endocrine System. The CABATEN Study October 7, 2020 March 2024
NCT00434109 Completed Phase 2 Phase II Study of Sunitinib Malate Following Hepatic Artery Embolization November 2006 February 2012
NCT00789841 Completed Gastrointestinal Motility in Patients With Neuroendocrine Tumors September 2008 May 2010
NCT00804336 Completed Phase 1 Pasireotide in Combination With RAD001 in Patients With Advanced Neuroendocrine Tumors October 2008 April 2015
NCT00942682 Completed Phase 1 Sorafenib in Combination With RAD001 in Patients With Advanced Neuroendocrine Tumors July 2009 March 2013
NCT01024387 Completed Phase 2 AMG 479 in Advanced Carcinoid and Pancreatic Neuroendocrine Tumors March 2010 January 2017
NCT00131911 Completed Phase 2 Sorafenib Tosylate in Treating Patients With Progressive Metastatic Neuroendocrine Tumors June 2005 April 2013
NCT00165230 Completed Phase 2 Thalidomide in Combination With Temodar in Patients With Neuroendocrine Tumors May 2002 July 2006
NCT00363051 Completed Phase 2 Safety/Efficacy of Everolimus in Adults With Advanced Pancreatic Neuroendocrine Cancer Not Responsive to Chemotherapy June 2006 April 2012
NCT01099540 Completed Phase 2 Study of Pazopanib Monotherapy in Patients With Unresectable, Metastatic Neuroendocrine Tumor April 2010 March 2013
NCT01476592 Completed N/A A Biological Study of Resveratrol's Effects on Notch-1 Signaling in Subjects With Low Grade Gastrointestinal Tumors December 2011 October 11, 2018
NCT01849523 Completed N/A Web-based Tailored Information and Support for Patients With a Neuroendocrine Tumor: a Randomized Pilot Study October 2013 August 2014
NCT01869725 Completed Phase 2 Comparative Study of Sensitivity of Ga-DOTATOC PET vs Octreoscan SPECT + CT April 1, 2013 December 26, 2018
NCT02147106 Completed Use of Video Consultation in Follow-up Care for Patients With a Neuroendocrine Tumor: a Feasibility Study May 2014 March 2017
NCT02472678 Completed N/A Web-based Tailored Information and Support for Patients With a Neuroendocrine Tumor May 2015 May 2017
NCT02481804 Completed N/A Optimal Feeding for NET Patients May 2015 March 2016
NCT03143946 Completed N/A DIVIT Study Diet and Vitamin Supplementation in Patients With a Neuroendocrine Tumor December 15, 2016 August 2019
NCT03197012 Completed Early Phase 1 Yttrium-90 DOTA-TOC Intra-arterial (IA) Peptide Receptor Radionuclide Therapy (PRRT) for Neuroendocrine Tumor July 1, 2017 May 31, 2019
NCT03411915 Completed Phase 1 A Study of XmAb®18087 in Subjects With NET and GIST January 22, 2018 October 26, 2021
NCT05816720 Completed Retrospective Analysis of Patients Re-treated With Lutetium-177 DOTATATE (Lutathera®) September 1, 2021 January 31, 2022
NCT02270567 Enrolling by invitation RegisterNET - A Registry for Neuroendocrine Tumors in the USA February 2015 December 2025
NCT04837885 Recruiting Phase 2 Intra-arterial Hepatic (IAH) Infusion of Radiolabelled Somatostatin Analogs in GEP-NET Patients With Dominant Liver Metastases September 24, 2021 September 24, 2024
NCT02628067 Recruiting Phase 2 Study of Pembrolizumab (MK-3475) in Participants With Advanced Solid Tumors (MK-3475-158/KEYNOTE-158) December 18, 2015 May 4, 2027
NCT05069220 Recruiting Early Phase 1 18F-MFBG PET/CT in the Evaluation of Neural Crest Tumor September 1, 2021 December 2026
NCT04907643 Recruiting N/A Virtual Reality for GI Cancer Pain to Improve Patient Reported Outcomes October 5, 2021 March 2026
NCT05749289 Recruiting Phase 2/Phase 3 Application of Al18F-octreotide PET/CT in Neuroendocrine Tumor December 20, 2022 December 20, 2025
NCT00227617 Terminated Phase 2/Phase 3 Combination Chemotherapy and Bevacizumab in Treating Patients With Advanced Neuroendocrine Tumors June 8, 2005 February 2016
NCT04073017 Terminated N/A Enterade in Carcinoid/Non-Carcinoid Syndrome Neuroendocrine Tumor Patients With Quality of Life Limiting Bowel Frequency November 4, 2019 May 18, 2021
NCT02177773 Terminated Phase 1/Phase 2 GA-68 DOTA-TOC of Somatostatin Positive Malignancies June 23, 2014 August 7, 2017
NCT01448083 Unknown status Heart/Mediastinal Ratio Study for Potential Equivalence of Heart/Mediastinal Ratios at One and Two Hours to the Traditional Heart/Mediastinal Ratio Obtained at Four Hours October 2011
NCT02092714 Unknown status Molecular Analysis in Tissue Samples From Patients With Advanced or Metastatic Neuroendocrine Tumors October 16, 2013 November 16, 2020
NCT02038738 Unknown status Phase 1/Phase 2 68Ga-DOTATATE PET Scan Imaging in Patients With Neuroendocrine Tumors March 2014
NCT00569738 Unknown status Ga68-DOTA-NOC-PET Imaging of Neuroendocrine Tumors December 2008 December 2010
NCT03466216 Unknown status Phase 1 Phase 1 Study of AlphaMedix™ in Adult Subjects With SSTR (+) NET February 5, 2018 July 1, 2022
NCT01048086 Withdrawn Phase 2 90Y DOTA/Retinoic Acid for Neuroblastoma and Neuroendocrine Tumor (NET) June 2009 November 2013
Disase is a (Disease Ontology)
DOID:170
Cross Reference ID (Disease Ontology)
ICD10CM:D3A.8
Cross Reference ID (Disease Ontology)
ICD9CM:209-209.99
Cross Reference ID (Disease Ontology)
ICDO:8240/3
Cross Reference ID (Disease Ontology)
MESH:D018358
Cross Reference ID (Disease Ontology)
NCI:C3809
Cross Reference ID (Disease Ontology)
SNOMEDCT_US_2023_03_01:55937004
Cross Reference ID (Disease Ontology)
UMLS_CUI:C0206754
Exact Synonym (Disease Ontology)
neuroendocrine neoplasm