pineoblastoma (Cancer)

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Information
Disease name
pineoblastoma
Disease ID
DOID:1664
Description
"A pineal gland neoplasm located_in the brain." [url:http\://en.wikipedia.org/wiki/Pinealoblastoma, url:https\://www.ncbi.nlm.nih.gov/pubmed/28327927]
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
Genes Mutation Description Source Links
NCT ID Status Phase Summary Start date Completion date
NCT06193759 Active, not recruiting Phase 1 Immunotherapy for Malignant Pediatric Brain Tumors Employing Adoptive Cellular Therapy (IMPACT) June 4, 2024 December 29, 2033
NCT01063114 Active, not recruiting N/A Proton Beam Radiotherapy for Medulloblastoma and Pineoblastoma April 2010 November 2025
NCT03500991 Active, not recruiting Phase 1 HER2-specific CAR T Cell Locoregional Immunotherapy for HER2-positive Recurrent/Refractory Pediatric CNS Tumors July 26, 2018 July 26, 2039
NCT03638167 Active, not recruiting Phase 1 EGFR806-specific CAR T Cell Locoregional Immunotherapy for EGFR-positive Recurrent or Refractory Pediatric CNS Tumors March 19, 2019 March 2040
NCT05934630 Active, not recruiting Testing Cerebrospinal Fluid for Cell-free Tumor DNA in Children, Adolescents, and Young Adults With Brain Tumors July 12, 2023 July 12, 2028
NCT02095132 Completed Phase 1/Phase 2 Adavosertib and Irinotecan Hydrochloride in Treating Younger Patients With Relapsed or Refractory Solid Tumors March 28, 2014 June 30, 2023
NCT00179803 Completed Phase 2 Stem Cell Transplant for High Risk Central Nervous System (CNS) Tumors March 1998 September 2009
NCT03434262 Completed Phase 1 SJDAWN: St. Jude Children's Research Hospital Phase 1 Study Evaluating Molecularly-Driven Doublet Therapies for Children and Young Adults With Recurrent Brain Tumors March 5, 2018 May 24, 2024
NCT02596828 Completed Phase 2 Prospective Pilot Trial to Assess a Multimodal Molecular Targeted Therapy in Children, Adolescent and Young Adults With Relapsed or Refractory High-grade Pineoblastoma April 2016 April 2021
NCT00565903 Completed Elucidating the Genetic Basis of the Pleuropulmonary Blastoma (PPB) Familial Cancer Syndrome March 2005 December 31, 2022
NCT00867178 Completed Phase 1 Vorinostat Combined With Isotretinoin and Chemotherapy in Treating Younger Patients With Embryonal Tumors of the Central Nervous System February 25, 2009 December 22, 2021
NCT01217437 Completed Phase 2 Temozolomide and Irinotecan Hydrochloride With or Without Bevacizumab in Treating Young Patients With Recurrent or Refractory Medulloblastoma or CNS Primitive Neuroectodermal Tumors November 22, 2010 June 30, 2021
NCT01884194 Completed Morphological Analysis of the Pineal Gland in Pediatric Retinoblastoma Patients Using Magnetic Resonance Imaging November 2013 February 2015
NCT03382158 Recruiting International PPB/DICER1 Registry December 6, 2016 December 6, 2035
NCT03990597 Withdrawn Phase 1 StrataXRT in Preventing Radiation Dermatitis in Pediatric Patients Undergoing Radiation Therapy to the Brain or Spinal Cord August 19, 2019 November 24, 2020
Disase is a (Disease Ontology)
DOID:5032
Cross Reference ID (Disease Ontology)
GARD:9369
Cross Reference ID (Disease Ontology)
ICDO:9362/3
Cross Reference ID (Disease Ontology)
MESH:D010871
Cross Reference ID (Disease Ontology)
NCI:C9344
Cross Reference ID (Disease Ontology)
SNOMEDCT_US_2023_03_01:31671006
Cross Reference ID (Disease Ontology)
UMLS_CUI:C0205898
Exact Synonym (Disease Ontology)
Pineal PNET
HPO alt_id (Human Phenotype Ontology)
HP:0040193
HPO Human Phenotype ID (Human Phenotype Ontology)
HP:0030408
OrphaNumber from OrphaNet (Orphanet)
251909