von Hippel-Lindau disease
Information
- Disease name
- von Hippel-Lindau disease
- Disease ID
- DOID:14175
- Description
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
| Genes | Mutation | Description | Source | Links |
|---|
| NCT ID | Status | Phase | Summary | Start date | Completion date |
|---|---|---|---|---|---|
| NCT04458935 | Active, not recruiting | Retrospective Case Series of Trans-scleral Cryotherapy for Retinal Hemangioblastoma | July 2, 2020 | June 30, 2024 | |
| NCT02108002 | Completed | Phase 1 | Effect of Vorinostat on Nervous System Hemangioblastomas in Von Hippel-Lindau Disease (Missense Mutation Only) | April 5, 2014 | September 12, 2018 |
| NCT00062166 | Completed | Natural History and Management of Pancreatic Lesions in Von Hippel-Lindau Disease | April 11, 2003 | November 29, 2017 | |
| NCT00970970 | Completed | Visualizing Vascular Endothelial Growth Factor (VEGF) Producing Lesions in Von Hippel-Lindau Disease | September 2009 | November 2012 | |
| NCT03108066 | Completed | Phase 2 | PT2385 for the Treatment of Von Hippel-Lindau Disease-Associated Clear Cell Renal Cell Carcinoma | April 24, 2017 | September 27, 2023 |
| NCT01168440 | Completed | Phase 2 | Study of Sunitinib in Patients With Von Hippel-Lindau (VHL) Disease | March 2010 | February 2011 |
| NCT00052013 | Completed | Phase 2 | Treatment of Von Hippel-Lindau (VHL)-Related Hemangioblastoma With PTK787/ZK 222584 | February 2003 | |
| NCT05843305 | Not yet recruiting | Phase 1 | A Study of BPI-452080 in Subjects With Solid Tumors | April 28, 2023 | October 31, 2025 |
| NCT05810246 | Recruiting | Phase 2 | 68Ga-NY104 PET/CT in Von Hippel-Lindau Disease | May 1, 2023 | December 31, 2025 |
| NCT06194669 | Recruiting | Mechanisms of Somatic Mutation and Tumor Initiation in Pre-malignant Kidney Tubule Cells | June 30, 2023 | December 31, 2027 | |
| NCT02420067 | Recruiting | Screening for Endolymphatic Sac Tumours (ELSTs) in Von Hippel-Lindau (vHL) Patients | February 2011 | December 2026 | |
| NCT03050268 | Recruiting | Familial Investigations of Childhood Cancer Predisposition | April 6, 2017 | March 31, 2037 | |
| NCT03749980 | Recruiting | MyVHL: Patient Natural History Study | January 2012 | December 2028 | |
| NCT04074135 | Recruiting | Phase 2 | Natural History and Management of Von Hippel-Lindau (VHL) Associated Pancreatic Neuroendocrine Tumors | June 2, 2020 | July 1, 2036 |
| NCT04924075 | Recruiting | Phase 2 | Belzutifan/MK-6482 for the Treatment of Advanced Pheochromocytoma/Paraganglioma (PPGL), Pancreatic Neuroendocrine Tumor (pNET), Von Hippel-Lindau (VHL) Disease-Associated Tumors, Advanced Gastrointestinal Stromal Tumor (wt GIST), or Solid Tumors With HIF-2α Related Genetic Alterations (MK-6482-015) | August 12, 2021 | February 26, 2027 |
| NCT05424016 | Recruiting | N/A | Propranolol and Von Hippel-Lindau Disease | January 16, 2023 | November 1, 2026 |
| NCT05737602 | Recruiting | N/A | Promoting Stress Management and Resilience Among Individuals With Von Hippel- Lindau Disease | July 1, 2024 | July 1, 2025 |
| NCT03979833 | Unknown status | Drivers of Hypoxia-induced Angiogenesis in Tumor Development | June 14, 2019 | May 31, 2020 |
- Disase is a (Disease Ontology)
- DOID:5241
- Cross Reference ID (Disease Ontology)
- GARD:7855
- Cross Reference ID (Disease Ontology)
- ICD10CM:Q85.83
- Cross Reference ID (Disease Ontology)
- MESH:D006623
- Cross Reference ID (Disease Ontology)
- MIM:193300
- Cross Reference ID (Disease Ontology)
- NCI:C3105
- Cross Reference ID (Disease Ontology)
- SNOMEDCT_US_2023_03_01:46659004
- Cross Reference ID (Disease Ontology)
- UMLS_CUI:C0019562
- Exact Synonym (Disease Ontology)
- Hippel Lindau syndrome
- Exact Synonym (Disease Ontology)
- von Hippel-Lindau syndrome
- OrphaNumber from OrphaNet (Orphanet)
- 892
- MeSH unique ID (MeSH (Medical Subject Headings))
- D006623