interstitial cystitis

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Information
Disease name
interstitial cystitis
Disease ID
DOID:13949
Description
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
Genes Mutation Description Source Links
NCT ID Status Phase Summary Start date Completion date
NCT05414305 Active, not recruiting Phase 2 The Female Microbiome in Patients Undergoing Bladder Instillation Therapy October 1, 2020 December 2023
NCT05485207 Active, not recruiting Early Phase 1 Transvaginal Botulinum Toxin A for Interstitial Cystitis / Bladder Pain Syndrome April 4, 2022 February 28, 2025
NCT00004316 Completed Phase 1/Phase 2 Phase I/II Randomized, Placebo-Controlled Study of Capsaicin for Interstitial Cystitis and Vulvar Vestibulitis June 1995
NCT00124306 Completed Phase 3 Efficacy of Amitriptyline for Painful Bladder Syndrome (PBS) February 2005 December 2008
NCT00150488 Completed N/A URACYST® For the Treatment of GAG Deficient Interstitial Cystitis September 2005 February 2008
NCT00194610 Completed Phase 4 Botox as a Treatment for Interstitial Cystitis in Women May 2004 September 2010
NCT00237081 Completed Genetics of Interstitial Cystitis June 2004 November 2008
NCT06209008 Completed Phase 3 Submucosal Intravesical Injection of Platelet-rich Plasma in the Treatment of Painful Bladder Syndrome April 1, 2021 December 1, 2023
NCT00256542 Completed Phase 2 Study of U101 for Bladder Pain and/or Urgency January 2006 September 2006
NCT00295854 Completed Phase 2 Phase II Study Efficacy and Safety of Two Dosing Regimens of MN-001 in Patients With Interstitial Cystitis May 2005 October 2006
NCT00376298 Completed Urology Database to Evaluate Clinical Information and Improve Patient Care. February 2004 December 2015
NCT00379002 Completed The Women's Urology Center/WISH Database Project July 2006 January 2015
NCT03463499 Completed N/A The Efficacy and Safety of Intravesical Hyaluronic Acid and Chondroitin Sulfate After Transurethral Resection of Hunner Lesion in Interstitial Cystitis/Bladder Pain Syndrome Patients September 22, 2017 December 31, 2021
NCT00056251 Completed Phase 2 Interstitial Cystitis January 2003 August 2003
NCT03103477 Completed Platelet Activating Factor Stability in Urine January 27, 2017 February 28, 2017
NCT03282318 Completed Phase 2 A Study to Investigate Efficacy, Safety, Pharmacodynamics and Pharmacokinetics of ASP6294 in the Treatment of Female Subjects With Bladder Pain Syndrome/Interstitial Cystitis September 28, 2017 March 21, 2019
NCT00420550 Completed Phase 2 Study of Biomarkers and the Relaxation Response Using Guided Imagery in Women With IC January 2007 December 2007
NCT00434343 Completed N/A Physical Therapy Trial for Pelvic Pain November 2006 November 2007
NCT05223244 Completed Phase 4 Bladder Capacity as Objective Measure of Intravesical Treatment of Newly Diagnosed IC October 1, 2011 March 30, 2020
NCT00517868 Completed Phase 2 Study of URG101 in Painful Bladder Syndrome and Interstitial Cystitis August 2007 April 2008
NCT00527917 Completed Phase 2 A Pilot Clinical Investigation of the Efficacy and Safety of Uracyst® Versus Placebo in Patients With Interstitial Cystitis/Painful Bladder Syndrome. September 2007 September 2008
NCT00546858 Completed Relationship of Interstitial Cystitis to Vulvodynia October 2007 May 2009
NCT00554320 Completed N/A Effect of Repetitive Transcranial Direct Current Stimulation (tDCS) on Chronic Pelvic Pain January 2009 June 2009
NCT00590473 Completed N/A Sacral Neuromodulation in Patients With IC April 2007 February 2009
NCT00704457 Completed Impact Of Sacral Neuromodulation On Urine Markers For Interstitial Cystitis (IC) February 2004 December 2007
NCT00733603 Completed N/A Physical Therapy in Women With Interstitial Cystitis June 2008 December 2009
NCT00739739 Completed Phase 2 An Effectiveness And Safety Study Of PD 0299685 For The Treatment Of Symptoms Associated With Interstitial Cystitis August 2008 January 2010
NCT00810329 Completed Proteomics of Cerebrospinal Fluid in Chronic Fatigue Syndrome July 2007 April 2011
NCT00817388 Completed Correlating Ic/Pbs Symptoms With Urine Biomarkers January 2009 May 2010
NCT05179460 Completed A Study of Pentosan Polysulfate Sodium and the Development of Pigmentary Maculopathy and Pigmentary Retinopathy October 26, 2021 May 20, 2022
NCT00873171 Completed Osteopathic Manipulation Therapy in the Treatment of Interstitial Cystitis January 2009 November 2009
NCT00903435 Completed Quantitative Studies of Urinary Bladder Sensation May 2007 November 2009
NCT00919113 Completed Phase 2 Efficacy and Safety Study of Uracyst to Treat Interstitial Cystitis/Painful Bladder Syndrome July 2009 December 2010
NCT00919802 Completed Phase 4 Intranasal Oxytocin for the Treatment of Pain Associated With Interstitial Cystitis June 2010 September 2015
NCT00971568 Completed Urinary Biomarkers Characteristic to Interstitial Cystitis September 2009 September 2011
NCT04824820 Completed N/A Improving Female Sexual Wellness April 10, 2021 April 5, 2023
NCT01083979 Completed N/A Intravesical Liposomes for Ulcerative Cystitis August 2010 October 2010
NCT01098279 Completed Chronic Pelvic Pain Study of Individuals With Diagnoses or Symptoms of Interstitial Cystitis and/ or Chronic Prostatitis December 2009 June 2014
NCT01138800 Completed Assessing Chronic Pain Conditions in Patients (Pts) With and Without (w&wo) Interstitial Cystitis May 2010 March 2012
NCT01150565 Completed Phase 1 Safety Study of LiRIS in Interstitial Cystitis (IC) Patients July 2010 September 2011
NCT01195116 Completed Phase 4 Usefulness of Dexmedetomidine on Post-operative Pain Management in Patients With Interstitial Cystitis May 2010 April 2012
NCT01197261 Completed Phase 2 OXN PR vs Placebo in Opioid-naive Subjects Suffering From Severe Pain Due to Bladder Pain Syndrome (BPS) September 2010 June 2013
NCT04821882 Completed N/A Intravesical Injection of Dextrose to Improve Lower Urinary Tract Symptoms Caused by Chronic Cystitis May 1, 2019 October 11, 2020
NCT04820855 Completed N/A Mindfulness and Yoga for Pain With Interstitial Cystitis Evaluation May 18, 2021 December 31, 2023
NCT01294878 Completed Phase 3 Omalizumab in Interstitial Cystitis/Bladder Pain Syndrome March 2009 October 2010
NCT01295814 Completed Phase 3 Efficacy Study of Adalimumab to Treat Interstitial Cystitis March 2011 July 2013
NCT04540887 Completed N/A PEMF Therapy to Treat Interstitial Cystitis/Bladder Pain Syndrome February 24, 2021 November 30, 2021
NCT04401176 Completed Phase 2 Bladder Instillations Versus Onabotulinumtoxin A for Treatment of Interstitial Cystitis/Bladder Pain Syndrome September 15, 2020 June 1, 2023
NCT04313972 Completed Phase 4 IC PaIN Trial: Interstitial Cystitis Pain Improvement With Naltrexone September 7, 2021 February 23, 2023
NCT04275297 Completed N/A Optimizing Psychosocial Treatment of Interstitial Cystitis/Bladder Pain Syndrome July 13, 2020 June 16, 2023
NCT01393223 Completed Phase 2 Evaluation of Intravesical LP08 in Patients With Interstitial Cystitis/Painful Bladder Syndrome July 21, 2015 June 14, 2018
NCT04208087 Completed Phase 1/Phase 2 PK and Safety of SI-722 in IC/BPS March 30, 2020 January 12, 2021
NCT04010513 Completed N/A Hypnosis for Bladder Pain Syndrome October 3, 2019 August 15, 2020
NCT01479725 Completed Phase 2 Prospective Trial Comparing Response to Hyperbaric Oxygen Treatment in Patients With Interstitial Cystitis March 2011 May 2013
NCT01559961 Completed Phase 1 Safety Study of Single Intravesical Doses of TTI-1612 in Women With Interstitial Cystitis/Bladder Pain Syndrome March 2012 June 2013
NCT03987594 Completed N/A Comparing the Effect of Fulguration Versus Fulguration and Hydrodistension in Interstitial Cystitis/Bladder Pain Syndrome August 1, 2015 October 31, 2018
NCT01731470 Completed N/A Intravesical Liposomes for Interstitial Cystitis/Painful Bladder Syndrome (IC/PBS) July 2012 August 2013
NCT01738464 Completed Microbiomes of Pelvic Pain June 2012 July 8, 2023
NCT03931538 Completed N/A Rapid Molecular Organism Identification and Mixed Flora Antibiotic Resistance Profiling (MixAR) Prospective Study July 17, 2018 October 1, 2019
NCT03844581 Completed N/A Effect of Interferential Electrical Stimulation on Pain Perception and Disability Level on Interstitial Cystitis January 1, 2019 February 13, 2019
NCT03844412 Completed Phase 2 Vestibulodynia: Understanding Pathophysiology and Determining Appropriate Treatments November 4, 2019 May 30, 2024
NCT01882543 Completed Phase 2 Efficacy and Safety of AQX-1125 in IC/BPS June 2013 June 2015
NCT01969773 Completed Phase 2 Intravesical Botulinum Toxin A Injections in Treatment of Interstitial Cystitis Refractory to Conventional Treatment December 2012 December 2014
NCT01985880 Completed The Efficacy of Biomarker in Patient With Interstitial Cystitis/Painful Bladder Syndrome November 19, 2013 May 12, 2016
NCT01990898 Completed Phase 2 Cyclosporine in Interstitial Cystitis: Efficacy, Safety and Mechanism of Action November 2013 April 2016
NCT01997983 Completed Phase 1/Phase 2 Efficacy and Safety of Intravesical Instillations of Botulinum Toxin in TC-3 Gel in IC Patients November 2013 August 2015
NCT02000401 Completed Phase 4 Intranasal Ketorolac Tromethamine (Sprix) for Acute Pain of Interstitial Cystitis Flare of Pain May 2012 July 2013
NCT02150811 Completed Observational Study of Hunner's Ulcer in Patient With Interstitial Cystitis/Bladder Pain Syndrome June 2, 2016 January 31, 2017
NCT02232282 Completed N/A Acupuncture for Female IC/PBSyndrome and Its Effect on the Urinary Microbiome: A Randomized Controlled Trial October 2014 August 16, 2017
NCT02247557 Completed Phase 2 Intravesical Instillation of Liposome Encapsulated Botulinum Toxin A (Lipotoxin) in Treatment of Interstitial Cystitis September 2014 February 2017
NCT02297100 Completed Phase 4 Intravesicular Onabotulinumtoxin A in Interstitial Cystitis December 2014 January 10, 2018
NCT02457182 Completed N/A Mindfulness-Based Therapy for Interstitial Cystitis/Bladder Pain Syndrome November 2014 June 2015
NCT02514265 Completed Trans-MAPP Symptom Patterns Study (SPS) July 1, 2015 June 2020
NCT03755375 Completed N/A Physiotherapeutic Interventions Applied to the Bladder Pain Syndrome February 5, 2018 December 19, 2019
NCT03722992 Completed N/A The Effects of Mindfulness-based Stress Reduction in Interstitial Cystitis Patients March 7, 2019 March 15, 2020
NCT02550561 Completed N/A Pilot Study of Percutaneous Posterior Tibial Nerve Stimulation for the Treatment of IC/PBS June 2015 March 2018
NCT03693001 Completed N/A HBOT for Patients With IC/FM (Interstitial Cystitis/Fibromyalgia) June 1, 2016 June 15, 2018
NCT03619486 Completed N/A Low Energy Shock Wave for the Treatment of Interstitial Cystitis/Bladder Pain Syndrome (IC/BPS) July 4, 2018 June 30, 2020
NCT02898220 Completed Trans-MAPP II Study of Urologic Chronic Pelvin Pain September 2016 June 2022
NCT03003845 Completed S1P1 Receptor Subtype (S1PR1) Axis in Patients With Interstitial Cystitis (IC) Pain February 26, 2019 February 27, 2020
NCT03023241 Completed N/A Diagnosis of Bladder Pain Syndrome / Interstitial Cystitis December 2004 July 2021
NCT03024619 Completed Interstitial Cystitis and Urinary pH February 2016 June 4, 2019
NCT03463915 Completed Phase 3 Clinical Trial Comparing Two Bladder Instillations for IC/BPS January 25, 2019 October 23, 2020
NCT03041194 Completed Dietary Impact on Urinary pH in Women With Interstitial Cystitis January 2015 December 2015
NCT05456308 Enrolling by invitation N/A What is the Optimal Technique for Hydrodistention? July 1, 2022 October 2024
NCT06212661 Enrolling by invitation Migraine Medication Effects on Urinary Symptoms April 5, 2024 May 2026
NCT06394830 Not yet recruiting Phase 2 Safety, Efficacy, and Frequency of Administration of VNX001 in the Treatment of Interstitial Cystitis / Bladder Pain Syndrome (IC/BPS) June 2024 June 2025
NCT04734106 Not yet recruiting Early Phase 1 Safety and Efficacy of Aloe Vera in the Management of the Symptoms of Interstitial Cystitis July 2024 October 2024
NCT05062902 Not yet recruiting Early Phase 1 A Novel Medical System for Quantitative Diagnosis and Personalized Precision Botulinum Neurotoxin Injection in Chronic Pelvic Pain Management December 2024 December 2027
NCT05857020 Not yet recruiting N/A Auricular Acupressure Therapy for Patients With IC/BPS July 2024 October 2025
NCT05912946 Not yet recruiting Phase 2/Phase 3 Assessing the Effectiveness and Safety of Interferon Bladder Infusion for the Treatment of Interstitial Cystitis October 15, 2023 October 15, 2024
NCT06013449 Not yet recruiting N/A Efficacy of Pulsed Electromagnetic Field and Heparin/Bupivacaine Instillations July 2024 January 2025
NCT06096597 Not yet recruiting Phase 2/Phase 3 Amniotic Membrane Therapy for Interstitial Cystitis/Painful Bladder Syndrome July 2024 June 2026
NCT06366269 Not yet recruiting N/A Acupuncture First for IC/BPS June 2024 June 2026
NCT03468530 Recruiting Therapeutic Effects of Endoscopic Ablation of Hunner Lesions in Interstitial Cystitis/ Bladder Pain Syndrome Patients August 1, 2012 December 31, 2025
NCT06299683 Recruiting N/A Pain Type and Interstitial Cystitis/Bladder Pain Syndrome Treatment May 1, 2024 August 4, 2028
NCT05276466 Recruiting N/A Assessment of Urinary Polymerase Chain Reaction (PCR) and Next Generation Sequencing (NGS) Technology in the Evaluation and Management of Females With Chronic Bladder Pain and Cystitis-like Symptoms February 1, 2022 December 15, 2023
NCT05275647 Recruiting Phase 2 Efficacy and Safety of Low Energy Shock Wave Plus BotulinumToxin A in Treating Patients With Interstitial Cystitis May 18, 2021 September 2024
NCT04845217 Recruiting Phase 1/Phase 2 Peppermint Oil for the Treatment of Interstitial Cystitis / Bladder Pain Syndrome September 15, 2021 December 2023
NCT03523559 Recruiting Genetic and Histopathologic Characteristics of Interstitial Cystitis March 31, 2018 December 2024
NCT05127616 Recruiting N/A EPPIC: Easing Pelvic Pain Interventions Clinical Research Program August 10, 2022 May 31, 2026
NCT05147779 Recruiting Phase 1 Safety of Cultured Allogeneic Adult Umbilical Cord Stem Cells for Peyronie's Disease, ED, and Interstitial Cystitis September 12, 2021 December 2025
NCT05149573 Recruiting N/A Investigation of PEMF Therapy for Female Patients With IC/BPS August 29, 2022 April 2025
NCT00499317 Recruiting Genetic Study of Chronic Prostatitis/Chronic Pelvic Pain Syndrome (CP/CPPS) January 15, 2007 December 31, 2026
NCT06232200 Recruiting N/A Investigation of the Effectiveness of Acupuncture in Patients Diagnosed With Interstitial Cystitis January 1, 2024 January 1, 2025
NCT05740007 Recruiting Phase 2 A Phase 2 Study of IW-3300 for the Treatment of Bladder Pain in Subjects With Interstitial Cystitis/Bladder Pain Syndrome March 28, 2023 November 2025
NCT05737121 Recruiting Phase 2 Safety and Efficacy Study of VNX001 Compared to Its Individual Components (Lidocaine and Heparin) or Placebo in Subjects With IC/BPS May 22, 2023 May 22, 2024
NCT05726786 Recruiting Phase 3 The Role of Preoperative Immunonutrition on Morbidity and Immune Response After Cystectomy (INCyst Trial) April 10, 2023 October 2026
NCT05699551 Recruiting N/A Supervised Exercise as a Therapeutic Strategy for Interstitial Cystitis/Bladder Pain Syndrome May 10, 2023 September 2025
NCT04734847 Recruiting N/A Motor Cortical Neuromodulation in Women With Interstitial Cystitis/Bladder Pain Syndrome June 1, 2021 August 15, 2025
NCT05658874 Recruiting Phase 3 A Multidisciplinary, Multimodal Bundled Care Approach to Chronic Pelvic Pain December 1, 2022 January 1, 2025
NCT00389142 Recruiting Identifying Genetic Causes of IC/BPS January 15, 2006 December 31, 2026
NCT04450316 Suspended Phase 2 Low-dose Naltrexone for Bladder Pain Syndrome October 8, 2020 October 2024
NCT02591199 Terminated Phase 2 Engage 24: Evaluation of the Safety and Effectiveness of URG101 in Subjects With Interstitial Cystitis/Bladder Pain Syndrome September 2015 June 18, 2018
NCT02517996 Terminated N/A Use of Preemptive Pudendal Nerve Block Prior to Hydrodistention for the Treatment of Interstitial Cystitis/Painful Bladder Syndrome (IC/PBS) February 2015 June 2018
NCT01824303 Terminated Phase 2 Safety, Tolerability and Efficacy Study of LiRIS® 400 mg in Women With Interstitial Cystitis March 2013 December 2014
NCT01813565 Terminated N/A The Efficacy of Additional Intravesical Instillation of Hyaluronic Acid/Chondroitin Sulfate to Transurethral Resection of Bladder Ulcer in Patients With Interstitial Cystitis/Bladder Pain Syndrome. March 20, 2013 December 1, 2016
NCT01678911 Terminated Phase 4 Efficacy of Gralise® for Chronic Pelvic Pain August 2012 June 2014
NCT01475253 Terminated Phase 2 Double-Blind Placebo Controlled Study of Safety,Tolerability, and Efficacy of LiRIS® in Women With Interstitial Cystitis November 2011 December 2012
NCT04268810 Terminated Phase 4 Prospective Trial Comparing Intravesical Chondroitin Sulphate 2% and DMSO in the Treatment of PBS/Interstitial Cystitis March 2010 December 31, 2013
NCT00086684 Terminated Phase 4 Effectiveness and Safety Study of Pentosan Polysulfate Sodium for the Treatment of Interstitial Cystitis September 2003 June 2011
NCT01280864 Terminated MAPP Investigation of Pelvic Floor-Brain Neurobiologic Axis in IC/IBS and IBS March 2010 August 2011
NCT00253006 Terminated Analysis of Expression of Nitric Oxide Syntheses and Their Functional Role in Human Urothelium January 2006 January 2008
NCT00451867 Terminated Phase 3 A Randomized Multicenter Double-Blind CT to Evaluate the Efficacy and Safety of Mycophenolate Mofetil . . . March 2007 April 2008
NCT00317070 Terminated Phase 2 Trial Comparing Intravesical Cocktail With Intravesical Dimethyl Sulfoxide (DMSO) in Painful Bladder Syndrome/Interstitial Cystitis (PBS/IC) April 2006 February 2009
NCT03480477 Terminated Adverse Childhood Experiences in Urogynecologic Patients April 9, 2018 February 1, 2019
NCT02547298 Terminated Interstitial Cystitis (IC)-Like Findings With Hydrodistension June 2015 January 18, 2018
NCT01069263 Unknown status N/A Comparative Study Between Hyperbaric Therapy and Intravesical Dimethyl Sulfoxide Instillation for Interstitial Cystitis February 2010 July 2015
NCT05337813 Unknown status N/A Effects of Low-intensity Excoporeal Shock Wave Therapy (LiESWT) on Women With Pelvic Floor Dysfunction April 10, 2020 March 31, 2023
NCT02858453 Unknown status Phase 3 Efficacy and Safety of 2 Doses of AQX-1125 in Subjects With Interstitial Cystitis / Bladder Pain Syndrome July 2016 February 2020
NCT04610359 Unknown status Phase 1 Safety of Human Embryonic Stem Cell (hESC)-Derived Mesenchymal Stem Cells in Interstitial Cystitis October 20, 2020 December 2022
NCT01838486 Unknown status N/A Bladder Thermal Distention for Patients With Interstitial Cystitis / Painful Bladder Syndrome June 2012 April 2014
NCT01301365 Unknown status Autonomic Response During Cystodistension in Patients Suspected of Having Interstitial Cystitis November 2010 June 2011
NCT00094874 Unknown status Phase 3 Acupuncture for the Treatment of Interstitial Cystitis (IC) Symptoms September 2004 September 2005
NCT01437579 Unknown status Phase 2 Efficacy of Botulinum Toxin Type A in Patients With Bladder Pain Syndrome/Intersticial Cystitis and Hunners' Lesions June 2011 June 2012
NCT03104361 Unknown status Phase 1 Platelet-Rich Plasma (PRP) Injection in Treatment of Interstitial Cystitis April 2017 July 2018
NCT04118946 Unknown status Phase 1/Phase 2 Platelet Enriched Plasma for Treatment of Interstitial Cystitis March 20, 2019 September 2020
NCT05155384 Unknown status N/A Biopsychosocial and Conventional Approach in Bladder Pain Syndrome November 12, 2021 October 15, 2022
NCT01255345 Unknown status Female Chronic Pelvic Pain January 2011 December 2012
NCT01311479 Unknown status N/A Osteopathic Manipulation for Female Interstitial Cystitis Patients With Sacroiliac Joint Dysfunction November 2009 October 2018
NCT01312259 Unknown status Phase 4 Clinical Efficacy of Changing the InterStim® Parameters in Patients With Interstitial Cystitis/Painful Bladder Syndrome April 2011 April 2018
NCT04447729 Withdrawn Phase 2 A Study to Test if Fremanezumab Reduces Pain in Patients With Interstitial Cystitis-Bladder Pain Syndrome October 15, 2020 February 10, 2022
NCT05226832 Withdrawn N/A Intradetrusor Triamcinolone Injection in the Management of Interstitial Cystitis/Bladder Pain Syndrome August 2022 March 2023
NCT04349930 Withdrawn Phase 1 The CBD-IC Randomized Controlled Trial: Evaluation of Hemp Cannabidiol SuppositoRies for Pain and Urinary SymptOms in INterstitial Cystitis (CHRONIC) January 2021 September 2022
NCT00823030 Withdrawn N/A Effect of Intravesical Lidocaine on Urodynamic and Symptomatic Parameters of Interstitial Cystitis January 2009 January 2013
NCT03027076 Withdrawn Microbiome of Urologic Chronic Pelvic Pain Syndrome November 2013 January 2015
NCT01378754 Withdrawn N/A Evaluate The Effectiveness Of Fospropofol (Lusedra®) For Induction Of Anesthesia June 2011 June 2014
Disase is a (Disease Ontology)
DOID:1679
Cross Reference ID (Disease Ontology)
GARD:6787
Cross Reference ID (Disease Ontology)
MESH:D018856
Cross Reference ID (Disease Ontology)
NCI:C27189
Cross Reference ID (Disease Ontology)
SNOMEDCT_US_2023_03_01:197834003
Cross Reference ID (Disease Ontology)
UMLS_CUI:C0282488
Exact Synonym (Disease Ontology)
ulcerative cystitis
OrphaNumber from OrphaNet (Orphanet)
37202