HELLP syndrome

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Information
Disease name
HELLP syndrome
Disease ID
DOID:13133
Description
"A severe pre-eclampsia characterized by hemolysis, elevated liver enzyme and low platelet count." [url:https\://www.ncbi.nlm.nih.gov/pubmed/24400024, url:https\://www.ncbi.nlm.nih.gov/pubmed/25879992]
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
Genes Mutation Description Source Links
NCT ID Status Phase Summary Start date Completion date
NCT00000534 Completed Phase 3 Calcium for Pre-Eclampsia Prevention (CPEP) March 1991 June 2000
NCT00097110 Completed Phase 3 RCT of Antioxidant Therapy to Prevent Preeclampsia in Brazil July 2003 December 2006
NCT01736826 Completed Free DNA and Nucleosome Concentrations in Pathological Pregnancies June 2015 December 17, 2018
NCT02754778 Completed N/A Influence of Conditional Workout Postpartum on Arterial Stiffness Among Women With Status After Preeclampsia, Superimposed Preeclampsia or HELLP-syndrome April 2016 March 2021
NCT02911701 Completed Phase 4 Effect of Acetaminophen on Postpartum Blood Pressure Control in Preeclampsia With Severe Features September 2016 January 10, 2018
NCT03111446 Completed N/A General Anesthesia Versus Spinal Anesthesia in Patients of HELLP Syndrome April 15, 2017 January 1, 2018
NCT03232359 Completed Immature Platelet Fraction as a Promising Biomarker in Prediction Outcome of HELLP Syndrome January 1, 2015 June 1, 2016
NCT03246542 Completed Promising Bimarker Prediction of Outcome of HELLP Syndrome. January 1, 2015 June 1, 2016
NCT03455387 Completed Evaluation of the Serum Markers sFLt1 and PlGF for the Prediction of the Complications of the Placental Vascular Pathologies in the 3rd Quarter of the Pregnancy. January 10, 2017 December 31, 2019
NCT03715647 Completed Correlation of Survival in Puerperae by Electrical Impedance Tomography January 2017 June 2018
NCT04216706 Completed Early Vascular Adjustments to Prevent Preeclampsia November 1, 2014 March 1, 2020
NCT04823949 Completed N/A Pregnancy-Related Hypertension: Adherence to a New Type of Monitoring April 15, 2021 January 18, 2022
NCT06452498 Not yet recruiting Phase 3 Preeclampsia Intervention Netherlands August 2024 July 2028
NCT03834285 Recruiting Liver Disease in Pregnancy May 9, 2019 April 8, 2025
NCT05500989 Recruiting PlacEntal Acute Atherosis RefLecting Subclinical Atherosclerosis November 2016 October 2024
NCT06377878 Recruiting The Preeclampsia Registry September 1, 2013 May 2040
NCT04725812 Terminated Phase 2 Complement Regulation to Undo Systemic Harm in Preeclampsia September 13, 2021 December 7, 2021
NCT00711841 Terminated Phase 4 Effectivity of Postpartum Dexamethasone for Women With Class I HELLP Syndrome July 2011 June 2019
NCT02807324 Unknown status Women Specific Cardiac Recovery After Preeclampsia June 2016 June 2022
NCT03605511 Unknown status TTP and aHUS in Complicated Pregnancies September 21, 2018 March 14, 2020
NCT02920593 Unknown status Phase 4 A Randomized Control Trial of Vitamin D Prophylaxis in the Prevention of Hypertensive Disorders of Pregnancy October 2016 March 31, 2019
NCT02247297 Unknown status Pancreatic Stone Protein (PSP) in Pregnant Women September 2014 September 2019
NCT01138839 Unknown status Phase 3 Dexamethasone Efficacy in HELLP I Syndrome October 2009 December 2012
Disase is a (Disease Ontology)
DOID:13129
Cross Reference ID (Disease Ontology)
GARD:8528
Cross Reference ID (Disease Ontology)
ICD10CM:O14.2
Cross Reference ID (Disease Ontology)
MESH:D017359
Cross Reference ID (Disease Ontology)
NCI:C84750
Cross Reference ID (Disease Ontology)
SNOMEDCT_US_2023_03_01:95605009
Cross Reference ID (Disease Ontology)
UMLS_CUI:C0162739
MedGen concept unique identifier (MedGen Concept name)
C0162739
MedGen unique identifier (MedGen Concept name)
58162
ICD10 preferred id (Insert disease from ICD10)
id-SRFSFto-be-added-later-1249554228785-18
ICD10 class code (Insert disease from ICD10)
O14.2
MeSH unique ID (MeSH (Medical Subject Headings))
D017359