Lewy body dementia

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Information
Disease name
Lewy body dementia
Disease ID
DOID:12217
Description
"A dementia that is characterized by the development of abnormal proteinaceous (alpha-synuclein) cytoplasmic inclusions, called Lewy bodies, throughout the brain that results in progressive decline in mental abilities." [url:http\://en.wikipedia.org/wiki/Dementia_with_Lewy_bodies, url:http\://www.mayoclinic.org/diseases-conditions/lewy-body-dementia/basics/definition/CON-20025038]
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
Genes Mutation Description Source Links
NCT ID Status Phase Summary Start date Completion date
NCT05524181 Active, not recruiting N/A Telehealth-enabled Integrated Palliative Care for People With Dementia June 29, 2022 August 14, 2024
NCT00820937 Completed N/A Diagnostic of Lewy Body Dementia by Combining Scintigraphy (SPECT) Using a Specific Transporter and Magnetic Resonance Imaging (MRI) March 2006 March 2008
NCT01339130 Completed N/A Assessment of Social-emotional Functioning in Neurological Diseases June 2009 June 2013
NCT02640729 Completed Phase 2 Study Evaluating Nelotanserin for Treatment of Visual Hallucinations in Subjects With Lewy Body Dementia December 2015 November 2017
NCT02860338 Completed COMPARATIVE EFFECTIVENESS OF MCI and DEMENTIA TREATMENTS IN A COMMUNITY-BASED DEMENTIA PRACTICE January 2009 December 2015
NCT00209456 Completed Phase 3 Dopamine Transporter Scintigraphy Imaging (DAT-Imaging) in Patients With Lewy Body Dementia November 2003
NCT03305809 Completed Phase 2 A Study of LY3154207 in Participants With Dementia Due to Lewy Body Dementia (LBD) Associated With Idiopathic Parkinson's Disease (PD) or Dementia With Lewy Bodies (DLB) November 9, 2017 July 10, 2020
NCT03550131 Completed N/A Innovations in Dementia Empowerment and Action December 5, 2018 May 16, 2023
NCT04413851 Completed Feasibility of Passive Data Collection in Dementia Subjects With Agitation June 1, 2020 December 6, 2021
NCT05499429 Not yet recruiting N/A Non-invasive Transcranial Focused Low-intensity Ultrasound Stimulation in Patients With Mild Lewy Body Dementia September 2022 November 2026
NCT06389032 Recruiting N/A PERSEVERE: Peer Mentor Support and Caregiver Education in Lewy Body Dementia May 13, 2024 June 30, 2028
NCT06263673 Recruiting Phase 4 Anti-Diabetic Medications to Fight PD and LBD May 7, 2024 June 30, 2024
NCT03019757 Recruiting Distinguishing Between Alzheimer's Disease, Lewy Body Dementia, and Parkinson's Disease August 30, 2018 December 2024
NCT03233646 Recruiting Retinal Imaging in Neurodegenerative Disease July 20, 2017 December 31, 2025
NCT06337578 Recruiting Advances in Telephone-based Cognitive Screening Procedures October 25, 2023 October 25, 2026
NCT05779839 Recruiting N/A A Study of Caregiver Connections Via Technology in Dementia February 22, 2023 December 2024
NCT05826457 Recruiting North American Prodromal Synucleinopathy Consortium Stage 2 August 12, 2022 May 1, 2025
NCT06005935 Recruiting Environmental and Reproductive Health Risk for Lewy Body Dementia August 1, 2023 July 31, 2024
NCT02871427 Terminated Phase 2 Open-label Study of Nelotanserin in Lewy Body Dementia With Visual Hallucinations or REM Sleep Behavior Disorder October 20, 2016 January 17, 2019
NCT05778695 Terminated N/A Brain Small Chain Fatty Acid Metabolism in Parkinson Disease: Ketones March 9, 2023 October 4, 2023
NCT05497817 Withdrawn N/A A Study to Evaluate Caregiver Connections Via Technology for Patients With Alzheimer's and Other Types of Dementia September 2022 December 2024
Disase is a (Disease Ontology)
DOID:1307
Cross Reference ID (Disease Ontology)
GARD:3243
Cross Reference ID (Disease Ontology)
ICD10CM:G31.83
Cross Reference ID (Disease Ontology)
ICD9CM:331.82
Cross Reference ID (Disease Ontology)
MESH:D020961
Cross Reference ID (Disease Ontology)
MIM:127750
Cross Reference ID (Disease Ontology)
NCI:C84826
Cross Reference ID (Disease Ontology)
SNOMEDCT_US_2023_03_01:192808003
Cross Reference ID (Disease Ontology)
UMLS_CUI:C0752347
Exact Synonym (Disease Ontology)
Dementia with Lewy bodies
Exact Synonym (Disease Ontology)
Diffuse Lewy body disease
Exact Synonym (Disease Ontology)
Lewy body disease
Exact Synonym (Disease Ontology)
Senile dementia of the Lewy body type
MedGen concept unique identifier (MedGen Concept name)
C0752347
MedGen unique identifier (MedGen Concept name)
199874