hepatorenal syndrome
Information
- Disease name
- hepatorenal syndrome
- Disease ID
- DOID:11823
- Description
- "An acute kidney failure that is characterized by severe renal vasoconstriction." [url:https\://www.ncbi.nlm.nih.gov/books/NBK470565/]
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
| Genes | Mutation | Description | Source | Links |
|---|
| NCT ID | Status | Phase | Summary | Start date | Completion date |
|---|---|---|---|---|---|
| NCT05434286 | Active, not recruiting | Point-of-Care Echocardiography to Assess Impact of Dynamic Cardiac Function, Renal and Cardiac Biomarkers in Cirrhosis With Hepatorenal Syndrome-Acute Kidney Injury | December 15, 2021 | June 15, 2023 | |
| NCT04460560 | Active, not recruiting | Phase 3 | Terlipressin for HRS-AKI in Liver Transplant Candidates (INFUSE) | December 11, 2020 | December 2025 |
| NCT00359853 | Completed | Phase 4 | Norfloxacin In The Primary Prophylaxis Of Spontaneous Bacterial Peritonitis | September 2000 | March 2005 |
| NCT00370253 | Completed | Phase 3 | Noradrenalin vs Terlipressin in Hepatorenal Syndrome | September 2006 | September 2007 |
| NCT05387811 | Completed | International Registry of Acute Kidney Injury in Cirrhosis: The GLOBAL AKI Project | July 1, 2022 | November 30, 2023 | |
| NCT00764049 | Completed | Phase 1/Phase 2 | Single Pass Albumin Dialysis in Patients With Cirrhosis | June 2009 | July 2012 |
| NCT01143246 | Completed | Phase 3 | A Placebo-Controlled, Double-Blind Study to Confirm the Reversal of Hepatorenal Syndrome Type 1 With Terlipressin | October 11, 2010 | May 10, 2013 |
| NCT01436500 | Completed | Phase 2 | Safety and Pharmacokinetics of Ifetroban in Hepatorenal Syndrome Patients | October 2011 | July 2015 |
| NCT05309200 | Completed | Phase 2 | A Study of OCE-205 in Participants With Cirrhosis With Ascites Who Developed Hepatorenal Syndrome-Acute Kidney Injury | April 28, 2022 | October 13, 2023 |
| NCT01932151 | Completed | N/A | Treatment of Type-1 Hepatorenal Syndrome Associated With Sepsis | December 2012 | August 2013 |
| NCT04416282 | Completed | N/A | Efficacy of Early Terlipressin Plus Albumin Therapy in Comparison to Standard Treatment for HRS-AKI in Acute-on-chronic Liver Failure. | June 22, 2020 | June 10, 2022 |
| NCT02097784 | Completed | N/A | Interest of the Echocardiography in the Management of Cirrhotic Patients With Acute Kidney Injury | March 2014 | July 2018 |
| NCT02770716 | Completed | Phase 3 | Study To Confirm Efficacy and Safety of Terlipressin in Hepatorenal Syndrome (HRS) Type 1 | July 13, 2016 | July 24, 2019 |
| NCT02789150 | Completed | Early Phase 1 | Outcomes of Renal Function in Hepatorenal Syndrome (HRS) Determined By Comparison of Target Mean Arterial Pressure (MAP) of 65 - 70 Mmhg Versus ≥ 85 Mmhg | January 2015 | January 11, 2018 |
| NCT00089570 | Completed | Phase 3 | Study of Terlipressin Versus Placebo to Treat Hepatorenal Syndrome Type 1 | June 2004 | September 2006 |
| NCT06256432 | Recruiting | Phase 2 | Endothelin Receptor Antagonism With Ambrisentan to Treat Hepatorenal Syndrome | April 17, 2024 | June 2025 |
| NCT04898010 | Recruiting | N/A | The Selective Cytopheretic Device (SCD) for Acute Kidney Injury (AKI) and Hepatorenal Syndrome (HRS) Type I | June 9, 2022 | October 2024 |
| NCT05346393 | Recruiting | N/A | HRS-AKI Treatment With TIPS in Patients With Cirrhosis | November 29, 2022 | June 2026 |
| NCT05875948 | Recruiting | Phase 2 | Study to Evaluate R2R01 Plus Terlipressin Versus Terlipressin Alone in Patients With Hepatorenal Syndrome | June 30, 2023 | December 2024 |
| NCT06000748 | Recruiting | Phase 2/Phase 3 | NEPH-ROSIS (NEPHrology in CirRhOSIS) Pilot Trial: A Trial to Treat Acute Kidney Injury Among Hospitalized Cirrhosis Patients | February 1, 2024 | May 1, 2024 |
| NCT06095440 | Recruiting | A Retrospective Analysis of Outcomes in Patients With Hepatorenal Syndrome at Methodist Dallas Medical Center | May 13, 2023 | May 13, 2024 | |
| NCT00287664 | Suspended | Phase 4 | Treatment of Hepatorenal Syndrome With Terlipressin Plus Albumin vs Albumin | February 2002 | September 2006 |
| NCT02123576 | Terminated | N/A | Treatment of Type I Hepatorenal Syndrome (HRS) With Pentoxyfylline | April 2014 | December 31, 2017 |
| NCT00734136 | Terminated | N/A | Role Of Angiogenic Factors In The Development Of Hepatorenal Syndrome | May 2005 | February 2009 |
| NCT00742339 | Terminated | Phase 2/Phase 3 | Terlipressin + Albumin Versus Midodrine + Octreotide in the Treatment of Hepatorenal Syndrome | May 2005 | October 2013 |
| NCT02049125 | Unknown status | Study of Accuracy of NGAL, a Renal Injury Biomarker, in Patients With Cirrhosis | June 2013 | March 2018 | |
| NCT02489864 | Unknown status | Phase 4 | The Effect of Terlipressin in the Prevention of Type 2 Hepatorenal Syndrome by Improving Mean Arterial Pressure | July 2015 | December 2017 |
| NCT02434445 | Unknown status | Use of Novel Plasma and Urinary Biomarkers to Predict the Development of Hepatorenal Syndrome in Cirrhotic Patients | July 2012 | July 2018 | |
| NCT03530761 | Unknown status | Korean Cohort Study of AKI & HRS in Cirrhosis | August 1, 2017 | December 31, 2019 | |
| NCT01587222 | Withdrawn | Phase 2 | Midodrine, Octreotide and Albumin: Impact on Renal Function of Patients With Liver Cirrhosis and Renal Failure | July 2016 | August 2017 |
| NCT01649037 | Withdrawn | N/A | To Compare the Efficacy of Nor Adrenaline and Terlipressin vs Step up Terlipressin Therapy in Hepatorenal Syndrome | August 2012 | June 2015 |
| NCT04048707 | Withdrawn | Phase 2 | Angiotensin 2 for Hepatorenal Syndrome | July 1, 2021 | July 1, 2023 |
- Disase is a (Disease Ontology)
- DOID:3021
- Cross Reference ID (Disease Ontology)
- GARD:6610
- Cross Reference ID (Disease Ontology)
- ICD10CM:K76.7
- Cross Reference ID (Disease Ontology)
- ICD9CM:572.4
- Cross Reference ID (Disease Ontology)
- MESH:D006530
- Cross Reference ID (Disease Ontology)
- NCI:C113400
- Cross Reference ID (Disease Ontology)
- SNOMEDCT_US_2023_03_01:51292008
- Cross Reference ID (Disease Ontology)
- UMLS_CUI:C0019212
- ICD10 preferred id (Insert disease from ICD10)
- D0008874
- ICD10 class code (Insert disease from ICD10)
- K76.7
- MeSH unique ID (MeSH (Medical Subject Headings))
- D006530