presbyopia
Information
- Disease name
- presbyopia
- Disease ID
- DOID:11638
- Description
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
| Genes | Mutation | Description | Source | Links |
|---|
| NCT ID | Status | Phase | Summary | Start date | Completion date |
|---|---|---|---|---|---|
| NCT04570579 | Active, not recruiting | Impact of a Novel Extended Depth of Focus Intraocular Lens on Visual and Lifestyle Enhancement | October 14, 2020 | April 30, 2024 | |
| NCT06438601 | Active, not recruiting | N/A | A Clinical Comparison of Two Multifocal Toric Soft Contact Lenses | April 25, 2024 | July 31, 2024 |
| NCT05863247 | Active, not recruiting | Ocular Biomarkers for Successful Premium Trifocal Intra-ocular Lenses Implantation | January 1, 2023 | December 2023 | |
| NCT03844828 | Active, not recruiting | N/A | Clinical Study to Investigate Outcomes of Trifocal Toric IOL POD FT in Asian Eyes | March 25, 2019 | December 2024 |
| NCT05578001 | Active, not recruiting | Phase 3 | Efficacy of Pilocarpine 1% in Presbyopia | July 1, 2022 | March 30, 2023 |
| NCT04654013 | Active, not recruiting | N/A | PROductivity Study of Presbyopia Elimination in Rural-dwellers III | May 21, 2022 | June 5, 2025 |
| NCT04465409 | Active, not recruiting | N/A | Evaluation of Safety and Efficacy of Intrastromal Implantation of CorVision® Bioengineered Corneal Inlay for Correction of Presbyopia. | March 25, 2020 | June 30, 2023 |
| NCT04151550 | Active, not recruiting | N/A | Safety & Efficacy of the Laser Scleral Microporation Procedure (Philippines) | September 25, 2019 | January 2025 |
| NCT06328660 | Active, not recruiting | N/A | Refitting Multifocal Contact Lens Wearers With a Different Multifocal Contact Lens | February 15, 2024 | June 18, 2024 |
| NCT00886119 | Completed | N/A | Comparison of a Multifocal Contact Lens to a Traditional Multifocal Contact Lens | April 2009 | May 2009 |
| NCT00909792 | Completed | N/A | Clinical Evaluation of Two New Silicone Hydrogel Multifocal Products | May 2009 | June 2009 |
| NCT00910403 | Completed | Phase 3 | Multicenter Evaluation of Safety and Effectiveness of Presbyopic LASIK for Hyperopes | June 2009 | May 2011 |
| NCT06270030 | Completed | Phase 1 | Safety, Tolerability and Pharmacokinetics of LNZ101 and LNZ100 Ophthalmic Solutions in Healthy Adult Chinese With Presbyopia | March 4, 2024 | April 10, 2024 |
| NCT00965237 | Completed | N/A | Multifocal Contact Lens Use in Previous Contact Lens Wearers With Near Vision Demands | August 2009 | December 2009 |
| NCT01016652 | Completed | N/A | Clinical Evaluation of a Multifocal Contact Lens on Symptomatic Patients | October 1, 2009 | December 1, 2009 |
| NCT01025050 | Completed | Phase 3 | Intrastromal Presbyopia Correction by Means of a Femtosecond Laser | December 2009 | December 2010 |
| NCT05936489 | Completed | Phase 1 | Plasma Pharmacokinetics and Safety of LNZ101 and LNZ100 Ophthalmic Solutions in Healthy Adult Subjects With Presbyopia | July 6, 2023 | October 3, 2023 |
| NCT05794126 | Completed | N/A | A Clinical Comparison of Two Soft Multifocal Contact Lenses | February 1, 2023 | March 23, 2023 |
| NCT01164358 | Completed | Long Term Observation of Patient Satisfaction Post INTRACOR Treatment Based on Patient Perception and Diagnostic Data | July 2010 | October 2013 | |
| NCT01166568 | Completed | N/A | Trial of the PresVIEW Implant for the Improvement of Near Vision in Patients With Presbyopia | December 2003 | March 2015 |
| NCT01234207 | Completed | N/A | Clinical Assessment of a Customized Free-form Progressive Addition Lens Spectacle | February 2009 | October 2009 |
| NCT01250054 | Completed | N/A | Comparison of Two Multifocal Contact Lenses | October 2010 | October 2010 |
| NCT01254760 | Completed | N/A | Comparison of Two Multifocal Contact Lenses Worn on a Daily Disposable Basis | December 2010 | January 2011 |
| NCT01268501 | Completed | N/A | Clinical Assessment of a Multifocal Contact Lens for People Who Use Reading Glasses Only | December 2010 | February 2011 |
| NCT01293240 | Completed | N/A | Prospective Study of Lens Performance of a Monthly Replacement Lens at Two Weeks and Four Weeks | December 2010 | April 2011 |
| NCT01322919 | Completed | Phase 3 | Safety and Efficacy Study to Evaluate the Treatment of Both Near and Distance Vision in a Simultaneous Laser Procedure | April 2010 | March 2012 |
| NCT01352442 | Completed | N/A | Safety and Effectiveness of the AcuFocus Corneal Inlay ACI7000PDT in Presbyopes | May 2011 | March 2014 |
| NCT01371539 | Completed | N/A | Clinical Comparison of Two Multifocal Contact Lenses Made of Silicone Hydrogel Materials | June 2011 | August 2011 |
| NCT01373580 | Completed | N/A | A Clinical Trial to Evaluate a Corneal Inlay for the Improvement of Near Vision in Presbyopic Patients | April 2010 | December 2016 |
| NCT01387360 | Completed | Phase 4 | Presbyopic Supracor Treatment for Near Myopic/Hyperopic Pseudophakic Eyes | June 2011 | October 2014 |
| NCT05763628 | Completed | N/A | Performance Evaluation of Different Daily Disposable Multifocal Contact Lenses | December 10, 2022 | June 15, 2023 |
| NCT05758883 | Completed | Post-approval Follow-up Study of the IC-8 Apthera Intraocular Lens (IOL) | January 12, 2023 | February 16, 2024 | |
| NCT01491360 | Completed | N/A | LaserACE® Procedure Restore Visual Function and Range of Accommodation LaserACE® Procedure | December 2013 | January 2016 |
| NCT01518868 | Completed | N/A | A Study to Evaluate the Feasibility of a High Add Multi Focal Contact Lens | January 2012 | February 2012 |
| NCT01526902 | Completed | N/A | Proclear 1-D Multifocal Nondispensing Study | February 2012 | May 2012 |
| NCT01539694 | Completed | N/A | A Study to Evaluate the Product Performance of a Low Add MultiFocal Soft Contact Lens | January 2012 | March 2012 |
| NCT01591499 | Completed | N/A | Clinical Evaluation of Biofinity Multifocal Compared With Air Optix Aqua Multifocal and With PureVision Multifocal | September 2011 | September 2012 |
| NCT01763047 | Completed | N/A | Evaluation of the Performance of Investigational Contact Lenses in a Presbyopic Population | November 2012 | February 2013 |
| NCT01797783 | Completed | N/A | Clinical Evaluation of the Safety and Efficacy of a New Multifocal Contact Lens | February 2013 | April 2013 |
| NCT01809197 | Completed | N/A | Silicone Hydrogel Contact Lens Clinical and Comfort Benefits With a Multi-Purpose Disinfecting Solution | April 2013 | July 2013 |
| NCT01895088 | Completed | N/A | A Continuation Study To Monitor The Long Term Safety Of Patients Completing Protocols ACU-P08-020/020A | May 2011 | August 2015 |
| NCT01933750 | Completed | N/A | Trial of the PresView Implant for the Improvement of Near Vision in Presbyopic Patients | February 2013 | March 2016 |
| NCT01951573 | Completed | N/A | Evaluation of a New Daily Disposable Multifocal Contact Lens Design | October 2013 | November 2013 |
| NCT01959178 | Completed | N/A | A Study to Evaluate a Mid Add Multi-Focal Soft Contact Lens | June 2013 | August 2013 |
| NCT05753189 | Completed | Phase 3 | Phase 3 Safety Study for the Treatment of Presbyopia Subjects | February 21, 2023 | February 9, 2024 |
| NCT01997216 | Completed | N/A | Multifocal Lens Design Evaluation | October 2012 | November 2012 |
| NCT05735990 | Completed | Retrospective Clinical Investigation of the Safety and Performance of 640PM Trifocal IOL Implantation in Patients With Cataract and/or Ametropia (Hyperopia, Myopia) and/or Presbyopia | October 27, 2022 | January 31, 2023 | |
| NCT05734846 | Completed | N/A | Multifocal Contact Lenses Fitting Methods Comparison | October 11, 2022 | December 1, 2022 |
| NCT02117544 | Completed | N/A | Multifocal High ADD Contact Lens Proof of Concept Trial | April 2014 | July 2014 |
| NCT02176343 | Completed | N/A | Retrospective / Prospective Clinical Study of AcrySof® IQ ReSTOR® +2.5 D Multifocal Toric Intraocular Lenses | July 21, 2014 | August 22, 2014 |
| NCT02189863 | Completed | N/A | Driving Simulator Study Comparing Two Modes of Presbyopic Correction With Contact Lenses | August 2014 | December 2014 |
| NCT02193555 | Completed | N/A | Visual Performance of Prototype Contact Lens Designs | July 2014 | November 2014 |
| NCT02197806 | Completed | Phase 2 | Safety and Efficacy of AGN-199201 and AGN-190584 in Patients With Presbyopia | July 2014 | November 2014 |
| NCT02214797 | Completed | N/A | Dispensing Study to Assess Visual Performance of Prototype Contact Lenses | September 2014 | June 2015 |
| NCT02223754 | Completed | N/A | Evaluation of an Investigational Multifocal Lens | August 2014 | November 2014 |
| NCT02228109 | Completed | N/A | Multifocal Lens Centration and Its Effect on Visual Performance in a Presbyopic Population | December 2014 | April 2015 |
| NCT02235831 | Completed | N/A | DAILIES® AquaComfort Plus® Multifocal (MF) - Comparative Assessment of Visual Performance | September 2014 | October 2014 |
| NCT05728944 | Completed | Phase 3 | Phase 3 Efficacy Study of LNZ101 for the Treatment of Presbyopia | April 24, 2023 | January 24, 2024 |
| NCT02310126 | Completed | N/A | Handling Comparison Between Two Contact Lens Types | November 1, 2014 | December 1, 2014 |
| NCT02374671 | Completed | N/A | A Clinical Trial of The VisAbility Micro Insert System for Presbyopic Patients | November 15, 2014 | April 13, 2018 |
| NCT02403180 | Completed | N/A | DAILIES® AquaComfort Plus® Multifocal (MF) - Comparative Assessment of Visual Performance | May 2015 | July 2015 |
| NCT02409771 | Completed | N/A | Clinical Trial With PRECIZON Presbyopic | June 2015 | January 17, 2017 |
| NCT05702541 | Completed | N/A | Assessing the Clinical Performance of Two Frequent Replacement Silicone Hydrogel Multifocal Contact Lenses | January 24, 2023 | February 21, 2023 |
| NCT02444130 | Completed | Presbyopia Compensation: Looking for Electrophysiological Predictors | February 2015 | February 2016 | |
| NCT02450747 | Completed | N/A | Performance of a Multifocal Contact Lens - Presbyopia Study | April 2015 | September 2015 |
| NCT02484586 | Completed | N/A | Dispensing Study to Assess the Visual Performance of Optimised Prototype Contact Lenses | October 2015 | February 7, 2017 |
| NCT02487160 | Completed | Phase 3 | Clinical Evaluation of the Lenstec SBL-3 Multifocal Intraocular Lens | August 2015 | August 2019 |
| NCT02516306 | Completed | Phase 1/Phase 2 | A Study to Evaluate the Safety and Efficacy of EV06 Ophthalmic Solution in Improving Vision in Subjects With Presbyopia | September 16, 2015 | March 10, 2016 |
| NCT02554396 | Completed | Phase 2 | Evaluation of the Efficacy and Safety of PRX-100 in the Treatment of Early to Moderate Presbyopia | September 2015 | November 2015 |
| NCT02595177 | Completed | N/A | Multifocal Intraocular Lens x Monovision x Hybrid Monovision After Bilateral Cataract Surgery | July 2014 | September 2015 |
| NCT02595528 | Completed | Phase 2 | A Study of the Concurrent Use of AGN-190584 and AGN-199201 in Participants With Presbyopia | April 29, 2016 | October 18, 2017 |
| NCT02612584 | Completed | N/A | Clinical Efficacy of the Pinhole Soft Contact Lenses for Correcting Presbyopia | January 1, 2016 | November 15, 2016 |
| NCT05665387 | Completed | Phase 2 | Study Assessing the Efficacy and Safety of STN1013600 Ophthalmic Solution 0.1% and 0.3% Compared With Placebo in Subjects With Presbyopia | December 22, 2022 | July 27, 2023 |
| NCT02719353 | Completed | N/A | A Dispensing Clinical Trial of Comfilcon A Extended Range Multifocal Lenses | March 2016 | August 2016 |
| NCT02719366 | Completed | N/A | A Dispensing Clinical Trial of Comfilcon A Extended Range Multifocal Lenses | March 2016 | August 2016 |
| NCT02740010 | Completed | The Visual Performances of a Progressive Multifocal Intraocular Lens With Extended Depth of Focus | September 2, 2020 | October 28, 2020 | |
| NCT02745223 | Completed | Phase 2 | Safety, Tolerability, and Efficacy of PresbiDrops (CSF-1), a Topical Ophthalmic Drug for Presbyopia | July 2016 | June 2017 |
| NCT02780115 | Completed | Phase 2 | A Safety, Efficacy and Pharmacokinetic Study of AGN-199201 and AGN-190584 in Patients With Presbyopia | May 26, 2016 | October 31, 2017 |
| NCT05656027 | Completed | Phase 3 | Phase 3 Evaluation of the Safety and Efficacy of LNZ101 for the Treatment of Presbyopia | December 19, 2022 | January 25, 2024 |
| NCT02838004 | Completed | N/A | Non-comparative Study to Assess the Visual Performances and Safety of a Progressive Multifocal Intraocular Lens | August 2016 | October 2017 |
| NCT02965664 | Completed | Phase 2 | Safety, Tolerability and Efficacy of PresbiDrops (CSF-1) in Presbyopic Subjects | December 2016 | April 2017 |
| NCT02965820 | Completed | N/A | OPTI-FREE® PureMoist® for Presbyopic Contact Lens Wearers | December 16, 2016 | April 1, 2017 |
| NCT02965833 | Completed | N/A | CLEAR CARE® PLUS for Presbyopic Contact Lens Wearers | December 13, 2016 | March 24, 2017 |
| NCT03001258 | Completed | Presbyopia Screening by Community Health Worker in Bangladesh | February 2015 | June 2015 | |
| NCT05646719 | Completed | Phase 3 | Safety and Efficacy of Nyxol Eye Drops as a Single Agent and With Adjunctive Low-Dose Pilocarpine Eye Drops in Subjects With Presbyopia | December 22, 2022 | October 11, 2023 |
| NCT05604781 | Completed | Symfony/Synergy IOL Combination Outcomes | October 17, 2022 | May 16, 2023 | |
| NCT03024073 | Completed | Assessment of Near Vision Capacity in Different Light Intensities | January 2017 | June 2018 | |
| NCT05579886 | Completed | N/A | Evaluating Two Multifocal Daily Disposable Contact Lenses | October 10, 2022 | February 7, 2023 |
| NCT03117426 | Completed | N/A | A Randomised Evaluation of Visual Function After Bilateral Implantation of Two Types of Presbyopia-correcting IOLs | January 1, 2017 | October 30, 2017 |
| NCT03118934 | Completed | N/A | Assessing Fitting Guides in Alcon Multifocal Contact Lenses | May 17, 2017 | July 28, 2017 |
| NCT05495971 | Completed | N/A | Extended Depth of Focus Contact Lenses for Presbyopia | September 6, 2022 | May 12, 2023 |
| NCT05494177 | Completed | Comparison of Premium Monovision and Bilateral Implantation of Trifocal Diffractive Intraocular Lenses | August 1, 2022 | March 1, 2023 | |
| NCT03201562 | Completed | Phase 2 | A Single-Center, Double-Masked Evaluation of the Efficacy and Safety of PRX-100 in the Treatment of Early to Moderate Presbyopia | April 30, 2017 | May 20, 2018 |
| NCT03226561 | Completed | N/A | Assessment of Near Vision Capacity in Different Light Conditions Following Bilateral Trifocal Intraocular Implantation | July 1, 2017 | June 1, 2018 |
| NCT03228199 | Completed | N/A | PROductivity Study of Presbyopia Elimination in Rural-dwellers (PROSPER) | July 24, 2017 | October 28, 2017 |
| NCT05464732 | Completed | N/A | Vivity IOL: Emmetropia Compared to Monovision. | September 3, 2020 | August 30, 2022 |
| NCT03268746 | Completed | N/A | Clinical Investigation of the Visual Outcomes and Safety of a Trifocal Intraocular Lens (IOL) in a Korean Population | January 9, 2018 | November 30, 2018 |
| NCT03297086 | Completed | N/A | Changes of Angle Kappa After Implantation of Multifocal Intraocular Lenses | December 1, 2015 | September 11, 2017 |
| NCT03306342 | Completed | N/A | Visual Performance, Patient Satisfaction and PCO Rate After Implantation of a Trifocal Hydrophobic IOL | February 2, 2018 | November 11, 2020 |
| NCT03306355 | Completed | N/A | Comparison of Clinical Outcomes on Trifocal IOLs FineVision POD F GF and FineVision POD F in Asian Eyes | December 4, 2017 | February 10, 2022 |
| NCT03314766 | Completed | Evaluation of Long-Term Clinical Acceptability and Satisfaction With the IC-8 Intraocular Lens | October 20, 2017 | November 27, 2018 | |
| NCT03320473 | Completed | N/A | IOL Implantation After KAMRA Inlay Removal | December 5, 2017 | June 20, 2022 |
| NCT05457608 | Completed | N/A | Clinical Evaluation of Two Multifocal Contact Lenses | June 25, 2022 | August 13, 2022 |
| NCT03341923 | Completed | N/A | Clinical Evaluation of DAILIES TOTAL 1® Multifocal Compared to 1-Day Acuvue® Moist® Multifocal in a Japanese Population | December 20, 2017 | June 5, 2018 |
| NCT03347981 | Completed | N/A | Clinical Study to Compare Visual Performance of Two Trifocal IOLs | October 2, 2017 | May 21, 2019 |
| NCT05431868 | Completed | Objective and Subjective Outcomes of a Trifocal IOL in Eyes With Different AL | January 1, 2019 | December 31, 2021 | |
| NCT03417557 | Completed | N/A | Clinical Validation Study of Comfilcon A Multifocal Toric Contact Lenses | January 12, 2018 | April 3, 2018 |
| NCT03499821 | Completed | N/A | Clinical Performance of a Phakic Intraocular Lens (IOL) | March 20, 2018 | July 9, 2019 |
| NCT05431543 | Completed | Phase 2 | Evaluation of the Safety and Effectiveness of Aceclidine (LNZ101) and Aceclidine + Brimonidine (LNZ100) in the Treatment of Presbyopia | August 6, 2022 | January 9, 2023 |
| NCT03519282 | Completed | N/A | Clinical Evaluation of Investigational Multifocal Toric Contact Lenses | April 25, 2018 | July 24, 2018 |
| NCT03519919 | Completed | N/A | Somofilcon A 1-Day Multifocal Study - Real World Subjective Acceptance Study | August 21, 2017 | February 15, 2019 |
| NCT03633695 | Completed | N/A | Clinical Evaluation of a Small Aperture Extended Depth of Focus Intraocular Lens | December 4, 2018 | October 15, 2020 |
| NCT03653715 | Completed | N/A | Bifocal Contact Lens Study for Adults With Age-Related Near Vision Loss | August 6, 2018 | October 12, 2018 |
| NCT05418153 | Completed | Synergy Lens Outcomes Evaluation | March 14, 2022 | November 22, 2022 | |
| NCT05393895 | Completed | Phase 3 | An Evaluation of the Safety of CSF-1 in Presbyopic Subjects | April 22, 2022 | December 1, 2022 |
| NCT03688399 | Completed | N/A | Comparison of Clinical Outcomes POD L GF vs POD F GF (PHY1707) | July 30, 2018 | September 21, 2021 |
| NCT03688425 | Completed | N/A | Comparison of Clinical Outcomes POD L GF vs POD F GF in Asian Eyes | October 9, 2018 | September 30, 2021 |
| NCT03688672 | Completed | N/A | Apioc Contact Lens Feasibility | October 1, 2018 | October 31, 2020 |
| NCT03716271 | Completed | N/A | The Light Sword Lens for Presbyopia Compensation | April 2016 | February 2018 |
| NCT03719196 | Completed | N/A | Reading Glass on Livelihoods and Quality of Life in Rural Bangladesh | April 30, 2017 | December 30, 2018 |
| NCT03733730 | Completed | N/A | Post Approval Study of the AcrySof® IQ ReSTOR® Toric IOLs | November 27, 2018 | October 14, 2022 |
| NCT05377515 | Completed | Evaluation of Visual Outcomes in Patients With Complex Corneas Implanted With the IC-8 IOL | February 10, 2022 | December 30, 2022 | |
| NCT03771274 | Completed | N/A | Tecnis ZLB00 & Symfony Intraocular Lens Combination Outcomes | December 7, 2018 | October 31, 2019 |
| NCT03790592 | Completed | N/A | Visual Outcomes After Presbyopic Lens Exchange | May 14, 2019 | December 9, 2019 |
| NCT03804268 | Completed | Phase 3 | Efficacy Study of Pilocarpine HCl Ophthalmic Solution (AGN-190584) in Participants With Presbyopia | December 21, 2018 | October 31, 2019 |
| NCT03809611 | Completed | Phase 2 | A Study of Safety and Efficacy of UNR844 Chloride (UNR844-Cl) Eye Drops in Subjects With Presbyopia. | April 26, 2019 | December 16, 2019 |
| NCT03811249 | Completed | N/A | Long Term Follow-up of the VisAbility™ Micro Insert System for Presbyopic Patients | December 3, 2018 | October 29, 2021 |
| NCT05364658 | Completed | N/A | A Clinical Evaluation of the LensGen Intraocular Lens | November 18, 2018 | January 30, 2020 |
| NCT03836898 | Completed | N/A | Presbyopic Phakic Intraocular Lens for Myopia Correction | January 1, 2016 | December 31, 2018 |
| NCT03857542 | Completed | Phase 3 | A Phase 3 Efficacy Study of Pilocarpine HCl Ophthalmic Solution (AGN-190584) in Participants With Presbyopia | March 1, 2019 | September 10, 2020 |
| NCT03885011 | Completed | Phase 2 | A Multi-Center, Double-Masked Evaluation of the Efficacy and Safety of CSF-1 in the Treatment of Presbyopia | February 26, 2019 | July 26, 2019 |
| NCT03911596 | Completed | Smart Autofocusing Eyeglasses | March 1, 2019 | December 30, 2022 | |
| NCT03974451 | Completed | N/A | A Comparison of FineVision Intraocular Lenses vs Symfony Intraocular Lenses | January 1, 2018 | September 2, 2019 |
| NCT05359380 | Completed | The Impact of Light Conditions on the Efficacy of Multifocal Intraocular Lens Implantation in Activities of Daily Living | September 15, 2021 | September 15, 2022 | |
| NCT05338333 | Completed | N/A | Clinical Performance Evaluation of Two Frequent Replacement Silicone Hydrogel Multifocal Contact Lenses | May 27, 2022 | September 1, 2022 |
| NCT05326607 | Completed | N/A | Pilot Clinical Investigation of Adaptative Eyeglasses for the Correction of Presbyopia | September 9, 2021 | January 27, 2022 |
| NCT04189224 | Completed | N/A | Evaluation of a Reusable Silicone Hydrogel Multifocal Contact Lens | November 15, 2019 | March 10, 2020 |
| NCT04208750 | Completed | Phase 4 | Clinical Investigation of the Vision-R800 Device. | November 18, 2019 | February 1, 2021 |
| NCT04242836 | Completed | Development and Validation of a Digital Optotype for Near Vision in Greek Language. | March 28, 2019 | November 28, 2019 | |
| NCT04263636 | Completed | Luminous Efficiency Function V(λ)' of Patients That Underwent Pseudophakic Presbyopic Corrections | January 7, 2020 | December 31, 2020 | |
| NCT05325931 | Completed | N/A | 1-Week Dispensing Evaluation of Kalifilcon A Daily Disposable Multifocal Compared to Ultra for Presbyopia | February 25, 2022 | March 28, 2022 |
| NCT04330001 | Completed | N/A | Exploratory Clinical Study for Techniques Associated With the Fluid Accommodating IOL | December 28, 2020 | May 3, 2023 |
| NCT05294328 | Completed | Phase 2 | Evaluation of the Safety and Effectiveness of Aceclidine/Brimonidine (LNZ101) and Aceclidine (LNZ100) in the Treatment of Presbyopia | May 5, 2022 | September 10, 2022 |
| NCT04392024 | Completed | N/A | Clinical Outcome of Extended-depth-of-focus Trifocal Intraocualr Lens (Triumf) Implantation | January 29, 2020 | January 26, 2022 |
| NCT05270863 | Completed | Phase 3 | Safety and Efficacy Study BRIMOCHOL™ PF and Carbachol PF in Subjects With Emmetropic Phakic or Pseudophakic Presbyopia | March 30, 2022 | April 10, 2023 |
| NCT04404725 | Completed | N/A | Comparing Biofinity Toric Multifocal to Ultra Multifocal for Astigmatism | August 6, 2020 | July 29, 2021 |
| NCT04437732 | Completed | N/A | Apioc Presbyopic Contact Lens | November 11, 2019 | June 9, 2021 |
| NCT04449263 | Completed | N/A | Comparing the Performance of 1 Day Multifocal Contact Lenses | July 27, 2020 | December 30, 2020 |
| NCT04474782 | Completed | Analysis of Defocus Curve of Pre-Presbyopic and Emerging Presbyopic Patients | October 17, 2019 | August 31, 2020 | |
| NCT05252871 | Completed | N/A | Assessment of Three Basic Progressive Lens Designs | December 9, 2021 | June 6, 2022 |
| NCT04591054 | Completed | N/A | Single-center, Double-arm, Prospective Clinical Trial to Compare Visual Performance of Non-diffractive Extended Vision and Neutral Aspheric Monofocal Intraocular Lenses | November 20, 2020 | August 24, 2022 |
| NCT04599933 | Completed | Phase 3 | An Evaluation of the Efficacy and Safety of CSF-1 in the Temporary Correction of Presbyopia (NEAR-1) | October 18, 2020 | February 19, 2022 |
| NCT04599972 | Completed | Phase 3 | An Evaluation of the Efficacy and Safety of CSF-1 in the Temporary Correction of Presbyopia (NEAR-2) | October 26, 2020 | January 28, 2022 |
| NCT04618224 | Completed | Development and Validation of an Internet-based Near and Intermediate-vision Reading Test | December 2, 2020 | February 10, 2021 | |
| NCT04618380 | Completed | Premium Monovision Versus Other Types of Monovision and Bilateral Trifocal Implantation. | January 1, 2018 | November 1, 2020 | |
| NCT05191329 | Completed | Impact of Personality on Satisfaction Following Presbyopic Correction | August 28, 2021 | March 25, 2022 | |
| NCT05124275 | Completed | Phase 2 | Safety and Efficacy of Pilocarpine Ophthalmic Topical Cream for the Treatment of Presbyopia | January 3, 2022 | September 6, 2022 |
| NCT04652037 | Completed | N/A | Visual Results of the Acrysof IQ Vivity Toric Extended Vision Intraocular Lens | March 17, 2021 | December 5, 2022 |
| NCT04883099 | Completed | N/A | APIOC for Presbyopia and APIOC for Presbyopia With Astigmatism | May 6, 2021 | October 31, 2021 |
| NCT04952701 | Completed | N/A | Evaluating the Success of Habitual Multifocal Wearers When Refit With a New Lens Design | October 21, 2021 | January 14, 2022 |
| NCT04983589 | Completed | Phase 3 | A Study to Assess Safety and Efficacy in Participants Age 40 to 55 With Presbyopia (Old Eye) Who Receive AGN-190584 in Both Eyes Twice Daily | September 2, 2021 | February 11, 2022 |
| NCT00635115 | Completed | N/A | The VEPRO Trial: A Cross-Over Randomised Controlled Trial Comparing 2 Corrective Lenses for Patients With Presbyopia | February 2006 | January 2007 |
| NCT00724945 | Completed | N/A | Comparison of Two Soft Bifocal Contact Lenses | July 2008 | August 2008 |
| NCT00808340 | Completed | N/A | Comparison of Three Soft Bifocal Contact Lenses | November 1, 2008 | December 1, 2008 |
| NCT00819299 | Completed | N/A | Safety and Effectiveness Study of the AcuFocus Corneal Inlay ACI 7000PDT in Presbyopes | December 2008 | September 2013 |
| NCT00823615 | Completed | N/A | Comparison of Two New Silicone Hydrogel Multifocal Products | December 2008 | February 2009 |
| NCT00850031 | Completed | N/A | Safety and Effectiveness Study of the AcuFocus Corneal Inlay ACI 7000PDT in Presbyopes | January 2009 | October 2013 |
| NCT04875455 | Completed | N/A | Premium Trifocal IOL Comparative Analysis | November 1, 2017 | November 17, 2021 |
| NCT05005624 | Completed | Validation of an Activities-of-daily-living Framework at Different Light Conditions | July 1, 2020 | June 30, 2021 | |
| NCT04657172 | Completed | Phase 3 | Safety & Efficacy of Pilocarpine Eye Solutions for Temporary Improvement of Near Vision in Presbyopic Adults | December 15, 2020 | March 26, 2021 |
| NCT04670575 | Completed | Vivity Outcomes in Patients With Early Stage Glaucoma | January 1, 2021 | November 30, 2022 | |
| NCT04675151 | Completed | Phase 2 | Safety and Efficacy of Nyxol With Pilocarpine Eye Drops in Subjects With Presbyopia | February 15, 2021 | June 30, 2021 |
| NCT04699266 | Completed | N/A | Clinical Investigation of the Multifocal IOL POD F GF in Cataracteous Eyes | November 1, 2020 | August 30, 2021 |
| NCT04734522 | Completed | N/A | Assessment of Progressive Lens Designs | October 19, 2020 | September 20, 2021 |
| NCT05114486 | Completed | Phase 3 | Safety & Efficacy of Pilocarpine Ophthalmic Spray for Temporary Improvement of Near Vision in Presbyopic Adults | November 3, 2021 | September 20, 2022 |
| NCT04755231 | Completed | N/A | Post-Market Clinical Study of the PanOptix Intraocular Lens (IOL) in a Chinese Population | April 19, 2021 | March 15, 2023 |
| NCT04774237 | Completed | Phase 2 | Safety and Efficacy Study of BRIMOCHOL™, BRIMOCHOL™ F, and Carbachol in Subjects With Emmetropic Phakic and Pseudophakic Presbyopia | March 24, 2021 | October 19, 2021 |
| NCT05069415 | Completed | N/A | Monofocal IOL Visual Outcomes When Targeting Mini Monovision | October 4, 2021 | November 30, 2022 |
| NCT05006898 | Completed | Phase 1 | Compound to Control Presbyopia Symptoms | June 1, 2020 | July 1, 2020 |
| NCT04837482 | Completed | Phase 3 | A Study to Assess the Impact and Adverse Events of Topical Eyedrops of AGN-190584 on Night-driving Performance in Participants, 40 to 55 Years of Age | May 14, 2021 | December 7, 2021 |
| NCT04841941 | Completed | N/A | A Feasibility Study to Assess the Visual Performance and Comfort of Hanita G4 Multifocal Soft Contact Lenses for Presbyopia at Normal Daily Routine Use | July 17, 2018 | February 16, 2021 |
| NCT05684237 | Enrolling by invitation | N/A | Using the VisuMax Femtosecond Laser System to Perform SMILE Optimized for Presbyopia by Modulation of Postoperative Spherical Aberration | October 13, 2023 | February 2026 |
| NCT05115058 | Enrolling by invitation | N/A | A New Successful Approach for Emmetropic Presbyopic Patients Using Intrastromal Pocket With Smile Module | June 1, 2016 | September 1, 2024 |
| NCT06461455 | Not yet recruiting | N/A | Clinical Performance Evaluation of Two Frequent Replacement Silicone Hydrogel Multifocal Toric Contact Lenses | July 2024 | November 2024 |
| NCT03173664 | Not yet recruiting | Post-Approval Study With the KAMRA Inlay | July 31, 2018 | January 2026 | |
| NCT04172935 | Not yet recruiting | N/A | Productivity Study of Presbyopia Improvement in Textile Workers | December 13, 2019 | December 31, 2049 |
| NCT05364983 | Not yet recruiting | N/A | Clinical Study to Evaluate the LensGen® Juvene® Intraocular Lens | May 2023 | November 2026 |
| NCT05506553 | Not yet recruiting | N/A | Comparison of Aspheric Toric Intraocular Lenses for Micro-monovision | September 2022 | September 2024 |
| NCT05531110 | Not yet recruiting | N/A | Comparison of Two Aspheric Intraocular Lenses for Micro-monovision | October 2022 | December 2024 |
| NCT05955846 | Not yet recruiting | N/A | Evaluation of Safety and Effectiveness of an IOL With a Virtual Aperture Optic | June 1, 2024 | September 2025 |
| NCT06369987 | Not yet recruiting | N/A | Visual Performance of Dailies Total1 Multifocal and Acuvue Oasys Max 1-Day Multifocal in Presbyopic Lens Wearers | May 2024 | October 2024 |
| NCT06400745 | Not yet recruiting | N/A | Clareon PanOptix Pro vs. Clareon PanOptix - Study A | June 2024 | July 2025 |
| NCT06401551 | Not yet recruiting | N/A | Clareon PanOptix Pro vs. Clareon PanOptix - Study B | June 2024 | July 2025 |
| NCT06451666 | Not yet recruiting | Phase 3 | Safety and Efficacy Study of Pilocarpine HCl Ophthalmic Solution in Participants With Presbyopia | June 2024 | December 2025 |
| NCT04629820 | Recruiting | N/A | PROductivity Study of Presbyopia Elimination in Rural-dwellers II | August 3, 2023 | June 30, 2024 |
| NCT06232590 | Recruiting | N/A | Performance Comparison of Two Monthly Replacement Silicone Hydrogel Multifocal Lens Types | March 1, 2024 | August 31, 2024 |
| NCT05411341 | Recruiting | Comparison of Two Different Optical Biometric Systems | July 1, 2023 | August 31, 2024 | |
| NCT05135286 | Recruiting | Phase 3 | Safety and Efficacy Study of BRIMOCHOL™ PF and Carbachol PF in Subjects With Emmetropic Phakic and Pseudophakic Presbyopia | March 15, 2022 | December 31, 2024 |
| NCT04632784 | Recruiting | N/A | Clinical Trial With Artiflex Presbyopic | November 12, 2021 | July 2025 |
| NCT05796453 | Recruiting | N/A | Post Market Clinical Follow-up (PMCF) Study of Clareon Vivity & Clareon PanOptix | September 19, 2023 | December 2027 |
| NCT06166901 | Recruiting | N/A | Evaluation of Long-term Safety and Performance of PanOptix Intraocular Lens (IOLs) | April 27, 2024 | December 2024 |
| NCT06460389 | Recruiting | Visual Outcomes After Extended Depth of Focus Intraocular Lens Implantation With and Without Digital Assistance | January 1, 2024 | December 31, 2024 | |
| NCT06045299 | Recruiting | Phase 3 | Evaluation of the Efficacy and Safety of LNZ101 and LNZ100 for the Presbyopia | September 27, 2023 | December 31, 2024 |
| NCT06053463 | Recruiting | N/A | Evaluation of Soft Multifocal Lenses in Presbyopic Previous Contact Lens Wearers | October 6, 2023 | September 1, 2024 |
| NCT06060041 | Recruiting | IC-8 Apthera IOL New Enrollment Post Approval Study | September 8, 2023 | September 30, 2027 | |
| NCT03135327 | Recruiting | N/A | Clinical Applications of Advanced Ophthalmic Imaging | January 1, 2007 | December 31, 2025 |
| NCT05510687 | Recruiting | N/A | Transforming Households With Refraction and Innovative Financial Technology | December 10, 2023 | June 2025 |
| NCT06260852 | Recruiting | Identification of Minimum Focal Points in Vision Curve Formation | February 1, 2024 | August 2024 | |
| NCT05574270 | Recruiting | N/A | Clinical Investigation of a Small Aperture Extended Depth of Focus Intraocular Lens in Patients With Complex Corneas | July 12, 2022 | January 12, 2024 |
| NCT05596682 | Recruiting | Prospective Multicenter Clinical Study on the Visual and Refractive Outcomes and Safety Outcomes Following Implantation of an AddOn Intraocular Lens in Previously Pseudophakic Eyes | October 17, 2022 | August 31, 2024 | |
| NCT06310252 | Recruiting | Safety and Efficacy of an Intrastromal Transform Corneal Allograft (TCA) for Presbyopia Correction - Long Term Follow-up | February 13, 2024 | September 2024 | |
| NCT03017612 | Terminated | N/A | A Clinical Trial to Evaluate the Safety and Effectiveness of the Raindrop Near Vision Inlay for Pseudophakic Subjects | July 2014 | December 2016 |
| NCT02806726 | Terminated | N/A | Clinical Investigation iDesign System With 1.3-PRESBY Treatment and STAR S4 IR™ Excimer Laser System | July 13, 2016 | November 9, 2017 |
| NCT03757039 | Terminated | N/A | Multifocal Visual Performance Study | December 16, 2018 | March 6, 2019 |
| NCT04806503 | Terminated | Phase 2 | A Dose-ranging Study to Evaluate the Safety and Efficacy of UNR844 in Subjects With Presbyopia. | June 30, 2021 | October 14, 2022 |
| NCT04037631 | Terminated | Compare Visual Outcomes Using a New Diagnostic Device | July 20, 2017 | May 1, 2020 | |
| NCT03101501 | Terminated | Phase 4 | A Prospective Study To Evaluate The Raindrop Near Vision Inlay In Presybopic or Pseudophakic Patients Treated With Mitomycin C Following Femtosecond Flap Creation. | February 14, 2017 | February 1, 2018 |
| NCT04403763 | Terminated | Phase 1/Phase 2 | Phase 1/2 Study of AGN-241622 in Healthy Participants and Participants With Presbyopia | July 27, 2020 | December 5, 2022 |
| NCT00585026 | Terminated | Phase 3 | Randomized Clinical Trial of Bifocal Lenses Versus Computer-specific Progressive Addition Lenses | October 2006 | June 2007 |
| NCT03671135 | Terminated | N/A | Safety and Efficacy of an Intrastromal Transform™ Corneal Allograft (TCA) for Presbyopia Correction | August 9, 2018 | December 31, 2021 |
| NCT04151446 | Terminated | N/A | Safety & Efficacy of the Laser Scleral Microporation Procedure (Taiwan) | April 23, 2019 | December 31, 2019 |
| NCT05068479 | Terminated | N/A | Safety & Efficacy of the Laser Scleral Microporation Procedure | April 29, 2021 | March 29, 2023 |
| NCT03326869 | Terminated | N/A | A Study Raindrop Near Vision Inlay in Presbyopes Implanted in Corneal Pockets | October 18, 2017 | October 23, 2018 |
| NCT03060954 | Terminated | N/A | Non-Inferiority Study Comparing MINI WELL READY® and FineVision® in Patients With Cataract Surgery | February 10, 2019 | March 5, 2020 |
| NCT01062412 | Terminated | N/A | Feasibility Study of Laser Treatment of the Crystalline Lens to Correct Presbyopia | December 2009 | October 4, 2011 |
| NCT02110472 | Unknown status | Phase 3 | Investigation of the Presbia Flexivue Microlens™ | May 2014 | February 2019 |
| NCT04522427 | Unknown status | N/A | Study of Presbyopia-correcting Intraocular Lenses in Eyes With Previous Corneal Refractive Surgery | September 1, 2020 | August 31, 2022 |
| NCT04391972 | Unknown status | N/A | Clinical Outcome of Extended-depth-of-focus Intraocualr Lens (SAV) Implantation | February 11, 2020 | January 22, 2021 |
| NCT04265846 | Unknown status | Prospective Clinical Study of Different Intraocular Lens Implantation Designed for the Correction of Presbyopia | May 31, 2020 | November 1, 2022 | |
| NCT03825081 | Unknown status | Early Phase 1 | Pilocarpine and Brimonidine in Patients With Monofocal Lenses | January 21, 2019 | December 31, 2019 |
| NCT00624039 | Unknown status | N/A | The Effect of Cataract Extraction on the Contractility of Ciliary Muscle | May 2006 | March 2008 |
| NCT05417633 | Unknown status | N/A | RayOne EMV Mini-monovision - Efficiency and Safety of 3 Grades of Mini-monovision | January 1, 2022 | March 21, 2023 |
| NCT03501654 | Unknown status | N/A | Prospective Clinical Trial of Unilateral or Bilateral Implantation of TecnisSymfony IOL in Cataract Patients With Presbyopia | February 17, 2017 | December 2018 |
| NCT03376412 | Unknown status | Phase 4 | A Study to Evaluate the Raindrop Near Vision Inlay Under Flap or Within Pocket | December 8, 2017 | December 2020 |
| NCT03242317 | Unknown status | Phase 4 | A Prospective Study to Evaluate the Raindrop Near Vision Inlay With Mitomycin C | June 16, 2017 | December 1, 2020 |
| NCT03126877 | Unknown status | Phase 4 | A Prospective Study to Evaluate the Raindrop Near Vision Inlay in Presbyopic Patients With Treatments to Optimize the Ocular Surface Before Implantation | April 10, 2017 | December 2020 |
| NCT03021512 | Unknown status | Functional Assessment of ADL in Patients Who Underwent Bifocal and Trifocal Presbyopic Correction | January 2017 | January 2018 | |
| NCT02668523 | Unknown status | Phase 3 | A Clinical Trial to Evaluate a Corneal Inlay for the Improvement of Near and Intermediate Vision in Pseudophakic Presbyopic Subjects | December 2015 | July 2018 |
| NCT02556944 | Unknown status | N/A | Mix and Match Study of Two Multifocal Intraocular Lens With Different Add Power | April 2015 | April 2016 |
| NCT02431156 | Unknown status | Functional Assessment of Activities of Daily Living (ADL) in Patients Who Underwent Mini-monovision Correction | March 2015 | June 2015 | |
| NCT02279446 | Unknown status | Development of a Validated Chart for Intermediate Vision Assessment | October 2014 | April 2015 | |
| NCT02112968 | Unknown status | Phase 4 | A Prospective Safety and Effectiveness Study of a New High Repetition Rate Excimer Laser Using LASIK for the Correction of Ammetropia and Presbyopia | December 2014 | May 2017 |
| NCT01977807 | Unknown status | Phase 4 | A Prospective Safety and Effectiveness Study of the 500 Hz Technolas Perfect Vision Excimer Laser in Asian Eyes Using LASIK | August 2014 | |
| NCT01443585 | Unknown status | N/A | Clinical Evaluation of a Progressive Addition Lens (PAL) | September 2012 | |
| NCT01404884 | Unknown status | Phase 3 | SUPRACOR for Myopia and Myopic Astigmatism | June 2011 | April 2016 |
| NCT01088282 | Unknown status | N/A | Visual and Economic Profits of ReSTOR® Multifocal Intraocular Lenses (IOL) on Public Health Patients in Spain | March 2010 | March 2011 |
| NCT00928122 | Unknown status | Phase 3 | Intrastromal Correction of Ametropia by a Femtosecond Laser | July 2008 | December 2012 |
| NCT05001243 | Unknown status | Phase 1 | Comparison of a Compound With Pilocarpine and Brimonidine to Improve Near Vision in Healthy Presbyopic Patients | August 10, 2021 | September 10, 2021 |
| NCT04904887 | Unknown status | N/A | Clinical Outcomes With a New Monofocal IOL Enhanced for Intermediate Vision | November 1, 2020 | October 30, 2021 |
| NCT05006911 | Unknown status | Phase 1 | Pilocarpine, Brimonidine, Oxymetazoline (PBO) Compound to Control Presbyopia Symptoms | August 14, 2021 | September 15, 2021 |
| NCT04739085 | Unknown status | Level of Agreement Between Clinical Defocus Curves and the Web-based Democritus Digital Acuity Reading Test wDDART | November 20, 2020 | May 20, 2021 | |
| NCT04733014 | Unknown status | Perceptions of Ophthalmologists Regarding Contemporary Presbyopia Management. | January 7, 2021 | February 7, 2021 | |
| NCT04054427 | Withdrawn | N/A | Implantation of a Trifocal Hydrophobic IOL in Patients That Underwent Refractive Surgery | November 2021 | May 2022 |
| NCT01059006 | Withdrawn | N/A | Peripheral PresbyLASIK Using the Allegretto Wavelight System For The Treatment of Presbyopia | January 2010 | July 2010 |
| NCT05624320 | Withdrawn | Phase 4 | Using AGN-190584 in Subjects Utilizing Single -Use Daily, Contact Lenses | December 1, 2022 | June 30, 2023 |
| NCT00271661 | Withdrawn | Presbyopia in Breast Cancer Survivors | August 2005 | May 2006 | |
| NCT05393089 | Withdrawn | Phase 2 | Study of AGN-190584 Eye Drops to Assess Safety and Efficacy in Participants Aged 40-80 Years With Pseudophakic Presbyopia | June 9, 2022 | April 4, 2023 |
| NCT03675438 | Withdrawn | N/A | Safety and Efficacy of a Sub-epitheilal Transform™ Corneal Allograft (TCA) for Presbyopia Correction | October 2018 | January 2021 |
| NCT04800016 | Withdrawn | N/A | Real-World Study of Vivity Intraocular Lenses (IOLs) | June 2021 | July 2024 |
- Disase is a (Disease Ontology)
- DOID:10034
- Cross Reference ID (Disease Ontology)
- ICD10CM:H52.4
- Cross Reference ID (Disease Ontology)
- ICD9CM:367.4
- Cross Reference ID (Disease Ontology)
- MESH:D011305
- Cross Reference ID (Disease Ontology)
- SNOMEDCT_US_2023_03_01:155135005
- Cross Reference ID (Disease Ontology)
- UMLS_CUI:C0033075
- MedGen concept unique identifier (MedGen Concept name)
- C0033075
- MedGen unique identifier (MedGen Concept name)
- 10912
- ICD10 preferred id (Insert disease from ICD10)
- D0006260
- ICD10 class code (Insert disease from ICD10)
- H52.4
- MeSH unique ID (MeSH (Medical Subject Headings))
- D011305