hydrocephalus
Information
- Disease name
- hydrocephalus
- Disease ID
- DOID:10908
- Description
- "A cerebral degeneration characterized by an abnormal accumulation of cerebrospinal fluid in the ventricles of the brain, leading to progressive enlargement of the head." [url:http\://en.wikipedia.org/wiki/Hydrocephalus, url:http\://ghr.nlm.nih.gov/glossary=hydrocephalus, url:http\://www.mayoclinic.org/diseases-conditions/hydrocephalus/basics/definition/con-20030706?_ga=1.124310025.2017809229.1415219956]
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
| Genes | Mutation | Description | Source | Links |
|---|
| NCT ID | Status | Phase | Summary | Start date | Completion date |
|---|---|---|---|---|---|
| NCT02230124 | Active, not recruiting | N/A | Magnetic Resonance Elastography in Hydrocephalus | March 1, 2007 | December 30, 2025 |
| NCT01936272 | Active, not recruiting | Phase 3 | Randomized Controlled Trial of Shunt vs ETV/CPC for PIH in Ugandan Infants | May 27, 2013 | December 2025 |
| NCT05068128 | Active, not recruiting | Combined Flow and Pressure Study of Craniospinal Dynamic | September 1, 2021 | September 2024 | |
| NCT05998473 | Active, not recruiting | Characterization of Dynamic Stability in Normal Pressure Hydrocephalus and Parkinson's Disease | June 1, 2023 | December 31, 2023 | |
| NCT06018545 | Active, not recruiting | AI Assisted Reader Evaluation in Acute Computed Tomography (CT) Head Interpretation | June 1, 2023 | September 1, 2024 | |
| NCT03327467 | Available | Expanded Access Protocol: Umbilical Cord Blood Infusions for Children With Brain Injuries | |||
| NCT00652470 | Completed | Phase 2 | A Study Comparing Two Treatments for Infants With Hydrocephalus | September 2005 | May 1, 2018 |
| NCT00692744 | Completed | Quality of Life in Elderly After Aneurysmal Subarachnoid Hemorrhage (SAH) | October 2008 | January 2014 | |
| NCT00743457 | Completed | Study of Ultrasound of the Eye for Children With Suspected Shunt Failure | August 2008 | March 2009 | |
| NCT00875758 | Completed | N/A | Optimizing Treatment of Post-hemorrhagic Ventricular Dilation in Preterm Infants | May 2009 | November 2013 |
| NCT01108965 | Completed | Study of Shunt Flow Sensor Accuracy in Extra-ventricular Drains. | August 2010 | May 2012 | |
| NCT01323764 | Completed | Phase 4 | ShuntCheck Versus Radionuclide in Evaluating Shunt Function in Symptomatic NPH Patients | June 2011 | July 2015 |
| NCT01556178 | Completed | Blood and Cerebrospinal Fluid for Pediatric Brain Tumor Research | July 2011 | April 2012 | |
| NCT01797627 | Completed | Ventricular Size Involvement in Neuropsychological Outcomes in Pediatric Hydrocephalus | August 2011 | August 2016 | |
| NCT01799018 | Completed | Role of Proteomics and Metallomics in Cerebral Vasospasm Following Subarachnoid Hemorrhage | April 2011 | June 2013 | |
| NCT01811589 | Completed | N/A | Guided Application of Ventricular Catheters | May 2013 | January 2015 |
| NCT03823430 | Completed | Pupillometry : Predictive Indicator in External Ventricular Drain Clamping ? | July 11, 2018 | March 11, 2021 | |
| NCT03595033 | Completed | N/A | Hydrocephalus iPad-App Based Intervention Study | November 24, 2015 | December 28, 2018 |
| NCT03513757 | Completed | Phase 4 | Dexmedetomidine and Propofol for Pediatric MRI Sedation | March 4, 2018 | October 21, 2018 |
| NCT00286104 | Completed | Phase 3 | Impact of Ventricular Catheter Used With Antimicrobial Agents on Patients With a Ventricular Catheter | April 2004 | June 2009 |
| NCT00001327 | Completed | Establishing the Physiology of Syringomyelia | July 29, 1992 | March 31, 2011 | |
| NCT00652197 | Completed | Monitoring Patient Cerebro-Spinal Fluid Drainage With an Ultrasonic Flow Sensor | March 2009 | May 2014 | |
| NCT04285489 | Completed | A Study on the Safety of Hakim Programmable Shunt System | May 2, 2020 | July 28, 2020 | |
| NCT04207229 | Completed | CERTAS Programmable Valve Registry | November 21, 2019 | November 18, 2021 | |
| NCT03451669 | Completed | Thermal Camera Detection of Ventriculoperitoneal Shunt Flow | April 16, 2018 | December 2, 2019 | |
| NCT03777774 | Completed | N/A | Subgaleal Drains in Decompressive Craniectomies | January 1, 2019 | June 30, 2020 |
| NCT03113799 | Completed | N/A | A Study Evaluate Aqueduct's Smart External Drain | April 12, 2017 | January 29, 2019 |
| NCT03230032 | Completed | N/A | Pacifier Activated Device and Mother's Voice in Infants at High-risk for Cerebral Palsy | June 9, 2017 | July 31, 2021 |
| NCT00280904 | Completed | A Registry for Comparing Catheter-Related Infection Rates Among Various Shunt Systems in the Treatment of Hydrocephalus | January 2006 | April 2008 | |
| NCT05534659 | Completed | Comparison of Programmable and Non-programmable CSF Shunts Among Adult Hydrocephalus Patients With Different Etiologies | January 1, 2017 | July 31, 2022 | |
| NCT01976559 | Completed | N/A | Comparison of Continuous Noninvasive and Invasive Intracranial Pressure Measurement--Celda Infusion Subprotocol | November 2013 | March 2014 |
| NCT05432986 | Completed | Assessment of CSF Shunt Flow With Thermal Measurements B | July 7, 2022 | November 10, 2023 | |
| NCT02381977 | Completed | Prevalence of Acute Critical Neurological Disease in Children: a Global Epidemiological Assessment | November 2011 | September 2014 | |
| NCT02404740 | Completed | Noninvasive Intracranial Pressure and Hydrocephalus Patients | February 2015 | September 2018 | |
| NCT05015751 | Completed | Assessment of CSF Shunt Flow With Thermal Measurements A | August 25, 2021 | July 13, 2022 | |
| NCT02575105 | Completed | BIS Monitoring of Patients With Hydrocephalus | May 2008 | May 2011 | |
| NCT00196196 | Completed | Phase 3 | A Precision and Accuracy Study of the Codman Valve Position Verification (VPV) System. | September 2004 | October 2006 |
| NCT04792944 | Completed | Brain Aneurysms: Utility of Cisternal Urokinase Irrigation | January 1, 2007 | December 31, 2020 | |
| NCT04567277 | Completed | N/A | Early Ventriculo-peritoneal Shunt in Subarachnoid Patients With External Ventricular Drainage | January 2017 | March 2021 |
| NCT04496414 | Completed | Bactiseal Catheter Safety Registry in China | September 1, 2020 | November 30, 2020 | |
| NCT06253858 | Not yet recruiting | N/A | Ultrasound (US) Guided External Ventricular Catheter Placement | July 1, 2024 | July 1, 2025 |
| NCT06276543 | Not yet recruiting | Bactiseal Catheter Safety Registry Study | June 1, 2024 | December 31, 2026 | |
| NCT06341946 | Not yet recruiting | N/A | Role of Endoscopic Third Ventriculostomy in Management of Malfunctioning Ventriculoperitoneal Shunt | April 5, 2024 | November 2025 |
| NCT06409286 | Not yet recruiting | Assessment of Flow in Cerebrospinal Fluid Shunts With a Second Generation Wireless Thermal Anisotropy Measurement Device | May 2024 | December 2024 | |
| NCT06410885 | Not yet recruiting | N/A | Assessment of Flow in Cerebrospinal Fluid Shunts With a Wireless Thermal Anisotropy Measurement Device in Asymptomatic Patients | June 2024 | December 2024 |
| NCT05386303 | Not yet recruiting | Quantitative Pupillometry | May 31, 2022 | September 1, 2024 | |
| NCT06368648 | Not yet recruiting | CoMind Early Feasibility Study | June 2024 | April 2025 | |
| NCT06428734 | Recruiting | Clinical Outcome in Patients With INPH | May 15, 2024 | May 2027 | |
| NCT02601339 | Recruiting | NIRS Monitoring in Premature Infants | April 2015 | December 2024 | |
| NCT03315637 | Recruiting | N/A | Fetal Endoscopic Surgery for Spina Bifida | January 2015 | December 31, 2024 |
| NCT03650101 | Recruiting | Improving Infant Hydrocephalus Outcomes in Uganda | May 5, 2021 | January 2026 | |
| NCT03840928 | Recruiting | PatientSpot Formerly Known as ArthritisPower | April 1, 2015 | March 1, 2025 | |
| NCT03948256 | Recruiting | N/A | Danish RAndomized Trial of External Ventricular Drainage Cessation IN Aneurysmal Subarachnoid Haemorrhage | June 6, 2019 | July 1, 2024 |
| NCT04099823 | Recruiting | N/A | MR Evaluation of Cerebrospinal Fluid (CSF) Dynamics | October 31, 2019 | January 2026 |
| NCT04177914 | Recruiting | Phase 3 | HCRN Endoscopic Versus Shunt Treatment of Hydrocephalus in Infants | July 21, 2020 | September 30, 2027 |
| NCT04189172 | Recruiting | MiDura-Study (Neuro-Patch in Duraplasty) | February 6, 2020 | January 2026 | |
| NCT04436068 | Recruiting | N/A | Hyperfine Portable MRI in Hydrocephalus and Other Conditions Prompting Outpatient Brain Imaging | June 28, 2019 | January 2027 |
| NCT04450797 | Recruiting | N/A | Intraoperative Ultrasound Guided Compared to Stereotactic Navigated Ventriculoperitoneal Shunt Placement | February 26, 2020 | February 2025 |
| NCT04746625 | Recruiting | Safety and Performance of the Polaris® 24 Adjustable Valve System in Hydrocephalus Patients' Treatment | June 4, 2021 | June 2028 | |
| NCT04758611 | Recruiting | N/A | The ETCHES I Study (Endovascular Treatment of Communicating Hydrocephalus With an Endovascular Shunt) | October 1, 2020 | December 1, 2026 |
| NCT05001750 | Recruiting | Phase 1 | Prophylactic Antibiotics Useful With Antibiotic Impregnated External Ventricular Drains (EVDs)? | June 14, 2021 | June 2024 |
| NCT05232838 | Recruiting | N/A | US Pilot Study of the CereVasc® eShunt® System in Normal Pressure Hydrocephalus | April 20, 2022 | October 30, 2029 |
| NCT05250505 | Recruiting | N/A | Pilot Study of the CereVasc® eShunt® System in Normal Pressure Hydrocephalus | March 10, 2022 | April 2027 |
| NCT05397106 | Recruiting | Post Market Clinical Follow-up of CODMAN CERTAS Programmable Valve | January 24, 2023 | September 30, 2027 | |
| NCT05399602 | Recruiting | N/A | The Role of Neurofilament Light (NfL) in Patients With Hydrocephalus | December 7, 2023 | December 31, 2024 |
| NCT05476874 | Recruiting | Phase 1/Phase 2 | Improvement of Peritoneal Catheter Placement in VPS With a Splitable Trocar | January 1, 2022 | June 30, 2023 |
| NCT05544279 | Recruiting | N/A | Caregiver Burden and Anxiety in Mothers of Children With Hydrocephalus | July 17, 2020 | December 30, 2022 |
| NCT05546996 | Recruiting | N/A | EVD Drainage Data and Intracranial Pressure (ICP) Measurements | July 11, 2023 | December 2025 |
| NCT05825521 | Recruiting | N/A | Impact of Cerebral Ventricular Dilatations and Cerebrospinal Fluid Pulsations on Periventricular White Matter in Hydrocephalic Patients | December 14, 2019 | December 2023 |
| NCT05910944 | Recruiting | European Study of Prodromal iNPH | November 1, 2023 | December 31, 2035 | |
| NCT06040697 | Recruiting | Formative Usability Assessment of Wireless Thermal Anisotropy Devices | September 29, 2023 | December 2024 | |
| NCT06086561 | Recruiting | N/A | Longitudinal Measurements of Flow in Cerebrospinal Fluid Shunts With a Wireless Thermal Anisotropy Measurement Device | November 17, 2023 | August 2024 |
| NCT06402786 | Recruiting | N/A | First-in-human Trial of Home Brain Pressure Measured Using Kitea ICP Sensor, Placed During Hydrocephalus Shunt Surgery. | May 27, 2024 | December 2025 |
| NCT06419842 | Recruiting | N/A | Impact of Hypnosis for Performing Lumbar Infusion Tests | May 14, 2024 | July 2026 |
| NCT02773888 | Suspended | N/A | An Evaluation of Non-Invasive ICP Monitoring in Patients Undergoing Invasive ICP Monitoring Via an Intraparenchymal Pressure Monitoring Device | December 2015 | December 2017 |
| NCT00946127 | Terminated | ETV Versus Shunt Surgery in Normal Pressure Hydrocephalus | March 2009 | October 2011 | |
| NCT02737163 | Terminated | Strata Programmable CSF Shunt Valve Study | April 1, 2016 | June 8, 2017 | |
| NCT02512809 | Terminated | Phase 3 | Isoflurane-induced Neuroinflammation in Children With Hydrocephalus | July 2015 | October 31, 2017 |
| NCT03471702 | Terminated | N/A | A Secondary Study Evaluating Aqueduct's Smart External Drain (SED) | February 28, 2018 | November 1, 2018 |
| NCT02408757 | Terminated | Sonographic Monitoring of Weaning of Cerebrospinal Fluid Drainages | September 2015 | November 27, 2023 | |
| NCT02900222 | Terminated | N/A | Study of Choroid Plexus Cauterization in Patients With Hydrocephalus | September 1, 2016 | May 16, 2018 |
| NCT01863381 | Terminated | N/A | Comparison of Continuous Non-Invasive and Invasive Intracranial Pressure Measurement | September 2014 | October 2015 |
| NCT05501002 | Terminated | N/A | Pilot Study to Evaluate the CereVasc® eShunt® System in the Treatment of Communicating Hydrocephalus | September 15, 2022 | September 15, 2023 |
| NCT01973764 | Terminated | N/A | Intraventricular Drain Insertion: Comparison of Ultrasound-guided and Landmark-based Puncture of the Ventricular System | November 2013 | May 2019 |
| NCT01863329 | Terminated | Comparison of Optic Nerve Sheath Diameter on Retrobulbar Ultrasound Before and After Drainage of Cerebrospinal Fluid in Patient With Hydrocephalus | March 2013 | September 2013 | |
| NCT01191307 | Terminated | Assess Specific Kinds of Children Challenges for Neurologic Devices Study | March 2009 | December 2014 | |
| NCT02988154 | Unknown status | Simulation Efficacy in Neurosurgical Education | June 2016 | ||
| NCT02775136 | Unknown status | N/A | An Evaluation of a Non-invasive Brain Monitor | October 2014 | December 2017 |
| NCT00886054 | Unknown status | The Prediction of Intracranial Pressure and Clinical Outcome by Transcranial Doppler in Neurocritical Patients | December 2009 | December 2010 | |
| NCT02425761 | Unknown status | Phase 3 | The CSF Shunt Entry Site Trial | April 1, 2015 | December 31, 2020 |
| NCT04060810 | Unknown status | N/A | Value of MRI CSF Flowmetry in Assessment of Grey Zone Hydrocephalic Patients | August 2019 | March 2021 |
| NCT02067364 | Unknown status | N/A | CRT ShuntCheck "Fit & Function" Study | January 2014 | August 2015 |
| NCT04785248 | Unknown status | N/A | Clinical Observation of V-P Shunt and Application of "Three-step Disinfection" to Reduce Post-operative Infection Rate | June 30, 2021 | April 1, 2024 |
| NCT04363658 | Unknown status | Efficacy Study of Hydrocephalus Surgery by Methods of Neuroelectrophysiology | May 10, 2020 | December 31, 2022 | |
| NCT05237102 | Unknown status | N/A | Prediction Model of Improvement of Disturbance of Consciousness in Patients With Hydrocephalus After Shunt Operation | April 10, 2022 | December 10, 2022 |
| NCT01865149 | Unknown status | Comparison of Optic Nerve Sheath Diameter on Retrobulbar Ultrasonography Before and After Drainage of Cerebrospinal Fluid in Pediatric Patient With Hydrocephalus | May 2013 | May 2014 | |
| NCT03516162 | Unknown status | Linking Digital Smartphone Behaviour With Brain Function | April 20, 2018 | December 2020 | |
| NCT03531723 | Unknown status | Brain Ultrasound in the Weaning of External Ventricular Leads | July 12, 2018 | June 2020 | |
| NCT03593330 | Unknown status | N/A | Neurosurgical Transitional Care Programme | April 15, 2018 | April 15, 2020 |
| NCT04773938 | Unknown status | Endoscopic Third Ventriculostomy for Adults: A Prognostic Model for Success | May 27, 2020 | August 2022 | |
| NCT02775669 | Unknown status | Non-invasive Epicutaneous Transfontanel Intracranial Pressure Monitoring in Children Under the Age of One: a Novel Technique | January 2015 | December 2017 | |
| NCT00652249 | Withdrawn | Diagnosing Malfunctioning Hydrocephalic Shunt Valves With a Flow Sensor | March 2009 | December 2010 | |
| NCT00651950 | Withdrawn | Bench Study of Transcutaneous Hydrocephalic Shunt Flow Sensor Alignment Accuracy and Repeatability | March 2009 | December 2010 | |
| NCT01878136 | Withdrawn | Phase 1/Phase 2 | Effect of Intraventricular tPA Following Aneurysmal Subarachnoid Hemorrhage | March 2015 | September 2016 |
| NCT02663947 | Withdrawn | Comparison of Optic Nerve Sheath Diameter Measured by Ultrasonography Before and After Ventriculoperitoneal Shunt Surgery in Adult Patients With Hydrocephalus | January 2016 | January 2017 |
- Disase is a (Disease Ontology)
- DOID:1443
- Cross Reference ID (Disease Ontology)
- GARD:6682
- Cross Reference ID (Disease Ontology)
- ICD10CM:G91
- Cross Reference ID (Disease Ontology)
- MESH:D006849
- Cross Reference ID (Disease Ontology)
- MIM:123155
- Cross Reference ID (Disease Ontology)
- MIM:236600
- Cross Reference ID (Disease Ontology)
- MIM:236635
- Cross Reference ID (Disease Ontology)
- MIM:307000
- Cross Reference ID (Disease Ontology)
- MIM:615219
- Cross Reference ID (Disease Ontology)
- NCI:C3111
- Cross Reference ID (Disease Ontology)
- ORDO:2182
- Cross Reference ID (Disease Ontology)
- ORDO:2185
- Cross Reference ID (Disease Ontology)
- SNOMEDCT_US_2023_03_01:267687006
- Cross Reference ID (Disease Ontology)
- UMLS_CUI:C0020255
- Exact Synonym (Disease Ontology)
- hydrocephalus, nonsyndromic, autosomal recessive
- Exact Synonym (Disease Ontology)
- hydrocephalus, X-linked
- HPO alt_id (Human Phenotype Ontology)
- HP:0007189
- HPO alt_id (Human Phenotype Ontology)
- HP:0008503
- HPO Human Phenotype ID (Human Phenotype Ontology)
- HP:0000238
- ICD10 preferred id (Insert disease from ICD10)
- D0005574
- ICD10 class code (Insert disease from ICD10)
- G91
- MeSH unique ID (MeSH (Medical Subject Headings))
- D006849