hereditary diffuse gastric cancer (Cancer)

Search with Google Search with Bing
Information
Disease name
hereditary diffuse gastric cancer
Disease ID
DOID:0080764
Description
"A diffuse gastric cancer that is characterized by characterized by the development of diffuse (signet ring cell) gastric cancer at a young age, associated with germline heterozygous mutations of CDH1, MAP3K6 and CTNNA1 genes." [url:https\://ghr.nlm.nih.gov/condition/hereditary-diffuse-gastric-cancer, url:https\://pubmed.ncbi.nlm.nih.gov/20591882/, url:https\://rarediseases.info.nih.gov/diseases/10900/disease]
Disease area statistics
Chromosome band
Gene symbol Chromosome Start Stop The number of variant
RNF139 8 124,474,880 124,488,618 2
CDH1 16 68,737,292 68,835,537 2
EPCAM 2 47,369,311 47,387,020 2
Annotation
Genes Mutation Description Source Links
NCT ID Status Phase Summary Start date Completion date
NCT04253106 Active, not recruiting N/A Liquid Biopsies for the Personalized Management of Patients With Hereditary Diffuse Gastric Cancer November 26, 2020 November 26, 2024
NCT00633607 Completed Hereditary Colorectal and Associated Tumor Registry Study April 2012 January 26, 2018
NCT03950908 Completed N/A Biopsy Technique for Endoscopic Surveillance of Hereditary Diffuse Gastric Cancer October 12, 2017 December 13, 2018
NCT06163365 Recruiting Inherited Cancer Early Diagnosis (ICED) Study July 26, 2022 July 26, 2025
Disase is a (Disease Ontology)
DOID:0080763
Cross Reference ID (Disease Ontology)
GARD:10900
Cross Reference ID (Disease Ontology)
MIM:137215
OrphaNumber from OrphaNet (Orphanet)
26106