desmoid tumor
Information
- Disease name
- desmoid tumor
- Disease ID
- DOID:0080366
- Description
- "A connective tissue benign neoplasm that occur most often in the abdomen, arms and legs." [url:https\://ghr.nlm.nih.gov/condition/desmoid-tumor, url:https\://rarediseases.org/rare-diseases/desmoid-tumor/, url:https\://www.ncbi.nlm.nih.gov/pubmed/28489620]
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
| Genes | Mutation | Description | Source | Links |
|---|
| NCT ID | Status | Phase | Summary | Start date | Completion date |
|---|---|---|---|---|---|
| NCT03785964 | Active, not recruiting | Phase 3 | Nirogacestat for Adults With Desmoid Tumor/Aggressive Fibromatosis (DT/AF) | April 17, 2019 | December 31, 2024 |
| NCT02076906 | Active, not recruiting | Phase 1 | MR-guided High Intensity Focused Ultrasound (HIFU) on Pediatric Solid Tumors | April 2014 | November 24, 2024 |
| NCT04871282 | Active, not recruiting | Phase 2/Phase 3 | A Study of AL102 in Patients With Progressing Desmoid Tumors | March 30, 2021 | February 25, 2025 |
| NCT05041036 | Available | Individual Patient Compassionate Use of Nirogacestat | |||
| NCT00287846 | Completed | Phase 1/Phase 2 | Imatinib Mesylate in Treating Patients With Recurrent or Refractory Fibromatosis | September 2004 | June 2010 |
| NCT00474994 | Completed | Phase 2 | Sunitinib in Treating Patients With Metastatic, Locally Advanced, or Locally Recurrent Sarcomas | April 2007 | November 2010 |
| NCT01137916 | Completed | Phase 2 | Study to Evaluate Imatinib in Desmoid Tumors | June 2010 | December 2016 |
| NCT01265030 | Completed | Phase 1/Phase 2 | A Pilot Study Evaluating the Use of mTor Inhibitor Sirolimus in Children and Young Adults With Desmoid-Type Fibromatosis | February 2014 | December 22, 2021 |
| NCT01286662 | Completed | A Cohort Study of Patients Treated With Brachytherapy for Selected Desmoid Patients in Gardner Syndrome | January 1978 | December 2010 | |
| NCT01567046 | Completed | Studying Genes in Tissue Samples From Younger and Adolescent Patients With Soft Tissue Sarcomas | May 2016 | May 2016 | |
| NCT03190174 | Completed | Phase 1/Phase 2 | Nivolumab (Opdivo®) Plus ABI-009 (Nab-rapamycin) for Advanced Sarcoma and Certain Cancers | August 24, 2017 | December 2, 2021 |
| NCT03459469 | Completed | Phase 1 | Phase I, Open-label, Non-randomized Study to Evaluate Safety of BC2059 | July 15, 2018 | May 1, 2022 |
| NCT03802084 | Completed | Phase 1/Phase 2 | A Study to Evaluate the Safety and Efficacy of Vactosertib and Imatinib in Patients With Advanced Desmoid Tumor | April 15, 2019 | March 26, 2024 |
| NCT04289077 | Completed | Quality of Life of Patients With Desmoid-type Fibromatosis | August 6, 2020 | February 1, 2021 | |
| NCT00002595 | Completed | Phase 2 | Toremifene in Treating Patients With Desmoid Tumors | July 1991 | September 2010 |
| NCT00003019 | Completed | Phase 2 | Vinblastine and Methotrexate in Treating Children With Desmoid Tumors | August 1997 | September 2006 |
| NCT00030680 | Completed | Phase 2 | Radiation Therapy in Treating Patients With Aggressive Fibromatoses | November 2001 | March 2012 |
| NCT00068419 | Completed | Phase 2 | Sulindac and Tamoxifen in Treating Patients With Desmoid Tumor | February 2004 | April 26, 2010 |
| NCT06195085 | Completed | CT-guided Radioactive Iodine-125 Seed Implantation for Recurrent Desmoid Tumors | July 1, 2013 | July 1, 2023 | |
| NCT02955446 | No longer available | Compassionate Use Protocol for PF-03084014 in Patients With Advanced Solid Tumor Malignancies | |||
| NCT06355921 | Not yet recruiting | N/A | A Prospective Clinical Study on the Safety and Efficacy of Radiofrequency Ablation for the Treatment of Patients With Desmoid Tumors | April 1, 2024 | May 1, 2028 |
| NCT05561036 | Recruiting | Phase 3 | A Randomized, Double-blind,Phase Ⅲ Study of Liposome Doxorubicin in Desmoid Tumor | September 29, 2020 | March 1, 2023 |
| NCT05949099 | Recruiting | Phase 2 | Study of Cryoablation and Nirogacestat for Desmoid Tumor | August 15, 2023 | February 1, 2028 |
| NCT06081400 | Recruiting | N/A | Cryoablation Versus Medical Therapy in Desmoid Tumors Progressing After Watchful Waiting | March 4, 2024 | June 2029 |
| NCT06258421 | Recruiting | Burden of Disease and Living Situation in Desmoid Patients | October 1, 2023 | December 2024 |
- Disase is a (Disease Ontology)
- DOID:0060123
- OrphaNumber from OrphaNet (Orphanet)
- 873