C1 inhibitor deficiency
Information
- Disease name
- C1 inhibitor deficiency
- Disease ID
- DOID:0060002
- Description
- "A complement deficiency that is a functional deficiency in the complement component C1 inhibitor leading to hereditary angioedema (HAE) involving swelling due to leakage of fluid from blood vessels into connective tissue." [url:http\://en.wikipedia.org/wiki/C1-inhibitor#Role_in_disease] {comment="ls:IEDB"}
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
| Genes | Mutation | Description | Source | Links |
|---|
| NCT ID | Status | Phase | Summary | Start date | Completion date |
|---|---|---|---|---|---|
| NCT05047185 | Active, not recruiting | Phase 2 | Dose-ranging Study of Oral PHA-022121 for Prophylaxis Against Angioedema Attacks in Patients With Hereditary Angioedema Type I or Type II | April 19, 2022 | December 2026 |
| NCT04618211 | Completed | Phase 2 | Dose-ranging Study of Oral PHA-022121 for Acute Treatment of Angioedema Attacks in Patients With Hereditary Angioedema | February 3, 2021 | March 1, 2023 |
| NCT06210698 | Not yet recruiting | Angioedema Biomarker Research Study | January 15, 2024 | February 1, 2026 | |
| NCT05396105 | Recruiting | Phase 2/Phase 3 | Extension Study of Oral PHA-022121 for Acute Treatment of Angioedema Attacks in Patients With Hereditary Angioedema | December 28, 2022 | December 2024 |
| NCT06343779 | Recruiting | Phase 3 | Study of Oral Deucrictibant Soft Capsule for On-Demand Treatment of Angioedema Attacks in Adolescents and Adults With Hereditary Angioedema | February 26, 2024 | March 2026 |
- Disase is a (Disease Ontology)
- DOID:626
- Exact Synonym (Disease Ontology)
- Quincke edema