cervical dystonia
Information
- Disease name
- cervical dystonia
- Disease ID
- DOID:0050840
- Description
- "A focal dystonia that is characterized by simultaneous contraction of the agonist and antagonist muscles that control the position of the head contracting during dystonic movement which causes the neck to involuntarily turn to the left, right, upwards, and/or downwards." [url:http\://en.wikipedia.org/wiki/Spasmodic_torticollis, url:http\://www.ncbi.nlm.nih.gov/books/NBK1155/]
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
| Genes | Mutation | Description | Source | Links |
|---|
| NCT ID | Status | Phase | Summary | Start date | Completion date |
|---|---|---|---|---|---|
| NCT05327985 | Active, not recruiting | Three-dimensional Analysis of Obliquus Capitis Inferior Muscle Function in the Rotatory Form of Cervical Dystonia | April 8, 2022 | August 2025 | |
| NCT00132990 | Completed | N/A | A Multicenter Pilot Study of Pallidal Deep Brain Stimulation for Cervical Dystonia | February 2003 | September 2005 |
| NCT00148889 | Completed | Phase 3 | Double-blind, Multicenter Study to Assess the Efficacy of Bilateral Pallidal Stimulation in Patients With Medically Refractory Primary Cervical Dystonia | July 2005 | April 2008 |
| NCT00165776 | Completed | Phase 2 | Randomized, Double-Blind, Placebo-Controlled, Parallel, Group Dose-Response, Study of E2014 in Patients WIth Spasmodic Torticollis | June 2004 | November 2006 |
| NCT00178945 | Completed | Phase 1/Phase 2 | Botulinum Toxin Type A (Botox) for the Treatment of Cervical Dystonia and Upper Thoracic Muscular Pain | March 2004 | March 2006 |
| NCT00210431 | Completed | Post Marketing Surveillance Study of Dysport | October 2004 | June 2006 | |
| NCT00257660 | Completed | Phase 3 | Randomized, Placebo-Controlled Study of AbobotulinumtoxinA (Dysport®) for the Treatment of Cervical Dystonia | October 10, 2005 | September 2006 |
| NCT00288509 | Completed | Phase 3 | Open-label Extension Study of AbobotulinumtoxinA (Dysport®) for the Treatment of Cervical Dystonia | February 2006 | January 2008 |
| NCT00323765 | Completed | Plasticity in Cervical Dystonia | May 5, 2006 | May 20, 2008 | |
| NCT00407030 | Completed | Phase 3 | IncobotulinumtoxinA (Xeomin) Versus Placebo in the Treatment of Cervical Dystonia | July 2006 | June 2009 |
| NCT00447772 | Completed | Phase 3 | Study to Assess the Efficacy and Safety of Dysport® in Cervical Dystonia | October 2004 | April 2008 |
| NCT00541905 | Completed | Phase 4 | Daily Dystonia Practice - A Trial to Investigate NT 201, the Duration of Treatment Effect After One Injection Session and in Long-term Treatment in Cervical Dystonia | September 2007 | May 2010 |
| NCT00564681 | Completed | Phase 2 | Study to Evaluate Safety, Efficacy of Botulinum Toxin Type A in Patients With Cervical Dystonia | December 2007 | December 2009 |
| NCT00702754 | Completed | Phase 4 | An Open Label Safety and Immunogenicity Study of MYOBLOC (Neurobloc; Botulinum Toxin Type B) Injectable Solution in Patients With Cervical Dystonia | June 2001 | September 2008 |
| NCT00703287 | Completed | N/A | Specialized Physiotherapy Program for Cervical Dystonia | January 2008 | December 2010 |
| NCT03905304 | Completed | Phase 3 | Efficacy and Safety of MEDITOXIN® in Cervical Dystonia | January 9, 2013 | August 5, 2014 |
| NCT03805152 | Completed | Phase 3 | Abobotulinum Toxin and Neubotulinum Toxin Injection in Cerivical Dystonia | October 25, 2019 | January 31, 2021 |
| NCT00132340 | Completed | Phase 1 | Deep Brain Stimulation to Treat Cervical Dystonia | August 2005 | July 2006 |
| NCT03969537 | Completed | Telemedicine Follow-up for Patients With Cervical Dystonia Treated With Neurotoxin Injections | April 1, 2019 | June 4, 2020 | |
| NCT04171258 | Completed | Phase 1 | Clinical Trial to Compare the Safety and Efficacy of Botulax® Versus Botox® in Patients With Cervical Dystonia | May 26, 2020 | October 26, 2021 |
| NCT04582929 | Completed | Phase 3 | Neubotulinum Toxin Injection in Cerivical Dystonia | January 3, 2019 | May 30, 2021 |
| NCT04849988 | Completed | Phase 2 | A Phase 2 Study to Evaluate the Safety and Efficacy of ABP-450 in the Treatment of Cervical Dystonia | March 29, 2021 | July 11, 2022 |
| NCT04871451 | Completed | Phase 2 | Extension Study of ABP-19000 to Evaluate Safety and Efficacy of Repeat Treatments of ABP-450 in Cervical Dystonia | July 27, 2021 | July 24, 2023 |
| NCT04916444 | Completed | N/A | Dystonia Treatment With Injections Supplemented By Transcranial Magnetic Stimulation | February 7, 2022 | December 7, 2022 |
| NCT04949594 | Completed | Relief of Pain in Patients With Cervical Dystonia Through the Use of Transcutaneous Electric Nerve Stimulation (TENS) | October 21, 2019 | July 30, 2020 | |
| NCT05103202 | Completed | Efficacy and Safety of 10-Week or Shorter vs 12-Week or Longer Injection Intervals of Botulinum Toxin | November 4, 2021 | June 14, 2022 | |
| NCT05157100 | Completed | Phase 4 | Clinical Study of Ingrezza (Valbenazine) for the Treatment of Cervical Dystonia | October 19, 2021 | September 15, 2023 |
| NCT00773253 | Completed | Phase 4 | Botox for Cervical Dystonia Following EMG Mapping | April 2008 | January 2011 |
| NCT00836017 | Completed | CD-PROBE: Cervical Dystonia Patient Registry for the Observation of onabotulinumtoxinA Efficacy | January 2009 | August 2013 | |
| NCT00950664 | Completed | Phase 4 | A Study to Compare Dysport® and Botox® in the Treatment of Cervical Dystonia | August 2009 | July 2011 |
| NCT01056861 | Completed | Effects of Botulinum Toxin in Cervical Dystonia | January 2010 | July 2014 | |
| NCT01180270 | Completed | Static Graviceptive Functions in Patients With Cervical Dystonia (CD) | June 2010 | January 2012 | |
| NCT01261611 | Completed | Phase 3 | Study Comparing Short Term Efficacy of Dysport and Dysport NG to Placebo, and to Assess Efficacy and Safety of Dysport NG of Subjects With Cervical Dystonia | April 2011 | June 2013 |
| NCT01287247 | Completed | Trial Evaluating Xeomin® (incobotulinumtoxinA) for Cervical Dystonia or Blepharospasm in the United States | February 2011 | April 2013 | |
| NCT01314365 | Completed | DYSPORT™ Clinical & Health Economics Outcomes Registry in Cervical Dystonia | April 2011 | March 2014 | |
| NCT01486264 | Completed | Phase 4 | Open-Label Non-Inferiority Study Evaluating the Efficacy and Safety of Xeomin® in Subjects With Cervical Dystonia Flex | January 20, 2012 | March 29, 2016 |
| NCT01588574 | Completed | Phase 2 | Study for Determine the Safety and Efficacy of Clostridium Botulinum Toxin Type A in Subjects With Cervical Dystonia | August 2012 | December 2013 |
| NCT01671527 | Completed | Insights Into Deep Brain Stimulation (DBS) for Cervical Dystonia | August 2012 | June 2016 | |
| NCT01753310 | Completed | Phase 3 | Efficacy and Safety of DYSPORT® Using 2mL Dilution in Adults With Cervical Dystonia. | January 2013 | January 2015 |
| NCT01753336 | Completed | Phase 3 | Long Term Safety And Effectiveness Of Dysport® In Adults With Cervical Dystonia | March 2013 | October 2015 |
| NCT01753349 | Completed | Phase IV-Cervical Dystonia-INTEREST IN CD2 | December 2012 | September 25, 2017 | |
| NCT01814774 | Completed | A Retrospective Chart Review of BOTOX® and Xeomin® for the Treatment of Cervical Dystonia and Blepharospasm | January 2013 | July 2013 | |
| NCT01840462 | Completed | Longitudinal Study for Treatment With Botulinum Toxin A Injections in naïve and Pre-treated Patients Suffering From Cervical Dystonia [CD-NIS-Longterm] | July 2012 | March 2016 | |
| NCT01859247 | Completed | N/A | Identification of Optimal Stimulation Site for Cervical Dystonia Symptoms: An Exploratory Study | March 2013 | June 2014 |
| NCT02069548 | Completed | Analysis of Three-dimensional Movements of the Head in Cervical Dystonia | February 2014 | April 2015 | |
| NCT02131467 | Completed | Phase 1/Phase 2 | Safety and Tolerability of Perampanel in Cervical Dystonia | September 1, 2017 | February 28, 2020 |
| NCT02175693 | Completed | Post-marketing Surveillance of Administration of Botulinum Toxin Type B(NerBloc)-Investigation of the Clinical Condition and Safety in Patients With Cervical Dystonia | April 2, 2013 | June 30, 2019 | |
| NCT02175719 | Completed | Post-marketing Surveillance of Administration of Botulinum Toxin Type B(NerBloc)-Investigation of the Clinical Condition in Patients With Change From Botulinum Toxin Type A | April 16, 2013 | December 31, 2017 | |
| NCT02177617 | Completed | Phase 4 | Neurotoxin and Physical Therapy | December 2014 | January 7, 2017 |
| NCT02245958 | Completed | A Retrospective Chart Review of BOTOX® and Xeomin® for the Management of Cervical Dystonia and Blepharospasm | August 2015 | December 2015 | |
| NCT02420106 | Completed | N/A | Effect of Osteopathic Manipulative Medicine on Motor Function and Quality of Life in Cervical Dystonia | February 2014 | February 2019 |
| NCT02468843 | Completed | Novel Stimulation Patterns for the Treatment of Dystonia | July 2015 | August 2016 | |
| NCT02504905 | Completed | Early Phase 1 | Propensity to Develop Plasticity in the Parieto-Motor Networks in Dystonia From the Perspective of Abnormal High-Order Motor Processing | August 20, 2015 | July 25, 2021 |
| NCT02689466 | Completed | Cholinergic Receptor Imaging in Dystonia | December 16, 2016 | November 26, 2021 | |
| NCT02834871 | Completed | N/A | Integration of the Cervical Proprioceptive Signals in Patients With Cervical Dystonia | March 2015 | July 2015 |
| NCT02959645 | Completed | Assessment of Brain Activities in Cervical Dystonia | September 1, 2017 | May 17, 2018 | |
| NCT03041714 | Completed | Neurophysiologic Study of Patient With Essential Tremor and Dystonic Tremor | April 7, 2017 | March 22, 2018 | |
| NCT03471923 | Completed | Non-Motor Features of Cervical Dystonia (CD) | March 26, 2018 | December 2, 2019 | |
| NCT03608397 | Completed | Phase 3 | Single Treatment of DaxibotulinumtoxinA for Injection in Adults With Isolated Cervical Dystonia (ASPEN-1) | June 20, 2018 | June 16, 2020 |
| NCT03617367 | Completed | Phase 3 | Long-Term Safety and Efficacy of Repeat Treatments of DaxibotulinumtoxinA for Injection in Adults With Isolated Cervical Dystonia (ASPEN-OLS) | September 5, 2018 | May 25, 2021 |
| NCT04432285 | Enrolling by invitation | Long-term Outcome of DBS Versus Botulinum Toxin Treatment in Cervical Dystonia | August 6, 2020 | December 31, 2024 | |
| NCT05715138 | Not yet recruiting | N/A | Comparison of Pallidal With Subthalamic Deep Brain Stimulation for Cervical Dystonia | September 1, 2023 | November 30, 2026 |
| NCT05884528 | Recruiting | Assessment of Long-term Clinical Response to BoNT in Cervical Dystonia | July 8, 2023 | May 2024 | |
| NCT04348669 | Recruiting | N/A | Tele-yoga and Dystonia | April 28, 2020 | December 2023 |
| NCT00760318 | Terminated | Phase 2 | Keppra for Cervical Dystonia | November 2005 | October 2007 |
| NCT02662530 | Unknown status | Phase 2 | Clinical and Kinematic Assessment for Determination of Botox® Injection Parameters in Cervical Dystonia | January 2012 | January 2021 |
| NCT01664013 | Unknown status | Phase 4 | The Impact of Botulinum Toxin Treatment in Quality of Life of Cervical Dystonia Patients | October 2012 | |
| NCT00418925 | Unknown status | Phase 2 | Efficacy of Dronabinol for the Treatment of Cervical Dystonia | September 2006 | December 2009 |
| NCT04057911 | Unknown status | N/A | A Trial of Non-invasive Stimulation in Cervical Dystonia | September 2019 | October 2021 |
| NCT04270214 | Unknown status | N/A | Conversion to Dysport in CD | June 1, 2020 | October 2022 |
| NCT02180139 | Withdrawn | N/A | tDCS in Cervical Dystonia | September 2017 | December 2017 |
- Disase is a (Disease Ontology)
- DOID:0050836
- Cross Reference ID (Disease Ontology)
- GARD:10668
- Exact Synonym (Disease Ontology)
- spasmodic torticollis