arrhythmogenic right ventricular cardiomyopathy
Information
- Disease name
- arrhythmogenic right ventricular cardiomyopathy
- Disease ID
- DOID:0050431
- Description
- "An intrinsic cardiomyopathy that is characterized by hypokinetic areas involving the free wall of the right ventricle, with fibrofatty replacement of the right ventricular myocardium, with associated arrhythmias originating in the right ventricle and limited or no involvement of the left ventricle." [url:http\://en.wikipedia.org/wiki/Arrhythmogenic_right_ventricular_dysplasia, url:http\://ghr.nlm.nih.gov/condition/arrhythmogenic-right-ventricular-cardiomyopathy, url:http\://my.clevelandclinic.org/services/heart/disorders/arvd, url:http\://www.hopkinsmedicine.org/heart_vascular_institute/clinical_services/centers_excellence/arvd/patient_resources/questions.html, url:https\://pubmed.ncbi.nlm.nih.gov/31637441/]
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
| Genes | Mutation | Description | Source | Links |
|---|
| NCT ID | Status | Phase | Summary | Start date | Completion date |
|---|---|---|---|---|---|
| NCT04124237 | Completed | Long Term Monitoring for Risk of Sudden Death | May 15, 2015 | August 30, 2020 | |
| NCT02291393 | Completed | N/A | The Role of High Density Surface ECG in the Diagnosis of Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) | August 2012 | October 2012 |
| NCT03177018 | Completed | N/A | DNA Analysis From Isolated Cardiomyocytes in the Molecular Diagnosis of Arrhythmogenic Right Ventricular Cardiomyopathy/Dysplasia | September 13, 2016 | December 31, 2018 |
| NCT03685149 | Completed | Phase 2 | Pilot Randomized Trial With Flecainide in ARVC Patients | July 31, 2019 | July 31, 2022 |
| NCT02302274 | Completed | Diagnostic Value and Safety of Flecainide Infusion Test in Brugada Syndrome | July 1, 2010 | July 26, 2017 | |
| NCT01804699 | Completed | National ARVC Data Registry and Bio Bank | January 2013 | August 2020 | |
| NCT00292032 | Completed | Registry of Unexplained Cardiac Arrest | May 2004 | August 30, 2020 | |
| NCT03527342 | Enrolling by invitation | Sahlgrenska Cardiomyopathy Project | June 1, 2018 | January 2029 | |
| NCT06174220 | Not yet recruiting | Phase 2 | Targeted Therapy With Glycogen Synthase Kinase-3 Inhibition for Arrhythmogenic Cardiomyopathy | April 1, 2024 | July 1, 2026 |
| NCT06311708 | Recruiting | Non-interventional Study of Seroprevalence of Pre-existing Antibodies Against Adenovirus-associated Virus Vector (AAV9) and the Progression of Disease in Patients With Plakophilin 2 (PKP2)-Associated Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) | January 31, 2023 | July 11, 2030 | |
| NCT02432092 | Recruiting | Pediatric Cardiomyopathy Mutation Analysis | April 2014 | December 31, 2030 | |
| NCT03049254 | Recruiting | Mayo AVC Registry and Biobank | February 9, 2018 | March 2025 | |
| NCT04265040 | Recruiting | DZHK TORCH-Plus is a Registry for Patients With Cardiomyopathies and Serves as Source for Cardiovascular Research Studies | August 18, 2020 | December 2027 | |
| NCT05024708 | Recruiting | N/A | Athlete's Heart or Arrhythmogenic Right Ventricular Cardiomyopathy: Contribution of Exercise Cardiovascular Magnetic Resonance (CMR) | January 16, 2023 | January 16, 2024 |
| NCT05799833 | Recruiting | Low QRS Voltages in Young Healthy Individuals and Athletes | October 9, 2023 | November 1, 2025 | |
| NCT06040242 | Recruiting | N/A | Arrhythmogenic Activity During Exercise in ARVC Patients | August 1, 2023 | August 31, 2025 |
| NCT06228924 | Recruiting | Phase 1 | Open-label, Dose Escalation Study of Safety and Preliminary Efficacy of TN-401 in Adults With PKP2 Mutation-associated ARVC | March 26, 2024 | October 1, 2029 |
| NCT03572569 | Unknown status | Risk Stratification in Children and Adolescents With Primary Cardiomyopathy | January 2013 | December 2020 | |
| NCT03076580 | Unknown status | An Integrative-"Omics" Study of Cardiomyopathy Patients for Diagnosis and Prognosis in China | July 1, 2015 | December 31, 2021 | |
| NCT03061994 | Unknown status | Metabolomic Study of All-age Cardiomyopathy | October 2016 | October 2020 | |
| NCT04895540 | Unknown status | South Asian Arrhythmogenic Cardiomyopathy Registry | April 10, 2021 | May 1, 2022 | |
| NCT02989480 | Unknown status | PET-detected Myocardial Inflammation is a Characteristic of Cardiac Sarcoid But Not of ARVC | August 2015 | July 2019 |
- Disase is a (Disease Ontology)
- DOID:0060036
- Cross Reference ID (Disease Ontology)
- MESH:D019571
- Cross Reference ID (Disease Ontology)
- MIM:PS107970
- Cross Reference ID (Disease Ontology)
- NCI:C84571
- Cross Reference ID (Disease Ontology)
- ORDO:217656
- Cross Reference ID (Disease Ontology)
- ORDO:247
- Cross Reference ID (Disease Ontology)
- SNOMEDCT_US_2023_03_01:281170005
- Cross Reference ID (Disease Ontology)
- UMLS_CUI:C0349788
- Exact Synonym (Disease Ontology)
- arrhythmogenic right ventricular dysplasia
- Exact Synonym (Disease Ontology)
- arrhythmogenic right ventricular dysplasia/cardiomyopathy
- Exact Synonym (Disease Ontology)
- ARVC
- Exact Synonym (Disease Ontology)
- ARVC cardiomyopathy
- Exact Synonym (Disease Ontology)
- ARVD
- Exact Synonym (Disease Ontology)
- right ventricular ACM
- OrphaNumber from OrphaNet (Orphanet)
- 247
- MedGen concept unique identifier (MedGen Concept name)
- C0349788
- MedGen unique identifier (MedGen Concept name)
- 87618