familial adenomatous polyposis
Information
- Disease name
- familial adenomatous polyposis
- Disease ID
- DOID:0050424
- Description
- "An intestinal disease that has_material_basis_in mutations in the APC gene and involves formation of numerous polyps in the epithelium of the large intestine which are initially benign and later transform into colon cancer." [url:http\://en.wikipedia.org/wiki/Familial_adenomatous_polyposis, url:http\://www.omim.org/entry/175100?search=adenomatous%20polyposis]
Disease area statistics
Chromosome band
Annotation
| NCT ID | Status | Phase | Summary | Start date | Completion date |
|---|---|---|---|---|---|
| NCT03806426 | Active, not recruiting | Phase 3 | Effect of EPA-FFA on Polypectomy in Familial Adenomatous Polyposis | December 5, 2018 | July 31, 2024 |
| NCT03847636 | Active, not recruiting | N/A | CryoBalloon Ablation for Treatment of Duodenal Adenomas | May 13, 2019 | May 2026 |
| NCT04230499 | Active, not recruiting | Phase 2 | Trial of eRapa to Prevent Progression in Familial Adenomatous Polyposis Patients Under Active Surveillance | January 18, 2021 | February 2023 |
| NCT00641147 | Completed | Phase 2 | Curcumin in Treating Patients With Familial Adenomatous Polyposis | October 2010 | November 30, 2016 |
| NCT00770991 | Completed | Phase 1 | Lyophilized Black Raspberries in Adults With Familial Adenomatous Polyposis (FAP) | December 2005 | December 2008 |
| NCT00808743 | Completed | Phase 2/Phase 3 | Prevention of Progression of Duodenal Adenomas in Patients With Familial Adenomatous Polyposis | May 2009 | January 2013 |
| NCT00927485 | Completed | N/A | Use of Curcumin for Treatment of Intestinal Adenomas in Familial Adenomatous Polyposis (FAP) | November 2007 | December 2016 |
| NCT01173250 | Completed | N/A | Is Diverting Ileostomy Necessary in Stapled Ileoanal Pouch? | ||
| NCT03494543 | Completed | Endoscopic Papillectomy for Ampullary Adenomas | January 1, 2005 | December 31, 2017 | |
| NCT00525655 | Completed | N/A | Multimedia Intervention in Patients With Familial Adenomatous Polyposis (FAP) | August 2007 | March 18, 2021 |
| NCT01725490 | Completed | Phase 2 | The Chemopreventive Effect of Metformin in Patients With Familial Adenomatous Polyposis: Double Blinded Randomized Controlled Study | February 15, 2013 | August 30, 2020 |
| NCT00033371 | Completed | Phase 2 | Celecoxib With or Without Eflornithine in Preventing Colorectal Cancer in Patients With Familial Adenomatous Polyposis | December 13, 2001 | March 24, 2009 |
| NCT02198092 | Completed | Preliminary Evaluation of Septin9 in Patients With Hereditary Colon Cancer Syndromes | July 2014 | August 2019 | |
| NCT04674228 | Completed | Review of Post-Study Clinical Endoscopy Reports in Follow Up to MAY2016-07-01 | May 7, 2021 | May 17, 2022 | |
| NCT02961374 | Completed | Phase 2 | Erlotinib Hydrochloride in Reducing Duodenal Polyp Burden in Patients With Familial Adenomatous Polyposis at Risk of Developing Colon Cancer | October 27, 2017 | September 27, 2021 |
| NCT00503035 | Completed | Phase 2 | Molecular Targeting of 15-Lipoxygenase-1 (15-LOX-1) for Apoptosis Induction in Human Colorectal Cancers | August 20, 2003 | April 2, 2021 |
| NCT01483144 | Completed | Phase 3 | Trial of Eflornithine Plus Sulindac in Patients With Familial Adenomatous Polyposis (FAP) | October 2013 | March 2019 |
| NCT01656746 | Completed | N/A | Single Incision Laparoscopic Surgery in Treating Patients With Colorectal Disease | May 2010 | October 2013 |
| NCT05402891 | Enrolling by invitation | Phase 2 | The CHAMP-study: The CHemopreventive Effect of Lithium in Familial AdenoMatous Polyposis | June 2, 2022 | April 30, 2025 |
| NCT05657145 | Enrolling by invitation | Visualization of the Papilla Through Use of the NuView Device in Patients With FAP | January 27, 2023 | December 15, 2024 | |
| NCT05630794 | Not yet recruiting | Phase 1 | Testing ONC201 to Prevent Colorectal Cancer | October 8, 2024 | January 1, 2028 |
| NCT06308445 | Not yet recruiting | Phase 2 | Safety Study for the Use of Rapamycin in Children With Familial Adenomatous Polyposis | August 1, 2024 | August 2029 |
| NCT04531930 | Not yet recruiting | Colorectal Adenoma Canceration in FAP | October 1, 2020 | September 30, 2030 | |
| NCT06435533 | Recruiting | N/A | Cold Atmospheric Plasma for the Endoscopic Treatment of Duodenal Polyps in Patients With Familial Adenomatous Polyposis | December 6, 2023 | March 2, 2025 |
| NCT02012699 | Recruiting | Integrated Cancer Repository for Cancer Research | November 1, 2013 | December 2099 | |
| NCT03050268 | Recruiting | Familial Investigations of Childhood Cancer Predisposition | April 6, 2017 | March 31, 2037 | |
| NCT03471403 | Recruiting | Cold Snare Polypectomy for Duodenal Adenomas in Familial Adenomatous Polyposis | October 10, 2017 | October 10, 2028 | |
| NCT04677998 | Recruiting | A Personalized Surveillance and Intervention Protocol for Duodenal and Gastric Polyposis in Patients With Familial Adenomatous Polyposis | November 24, 2020 | November 2025 | |
| NCT04678011 | Recruiting | A Personalized Surveillance and Intervention Protocol for Patients With Familial Adenomatous Polyposis That Have Undergone (Procto)Colectomy | November 24, 2020 | November 2025 | |
| NCT04865601 | Recruiting | DNA Adductomics for Colorectal Cancer Investigation | February 15, 2021 | December 31, 2025 | |
| NCT05223036 | Recruiting | Phase 2 | Testing Obeticholic Acid for Familial Adenomatous Polyposis | January 19, 2023 | February 21, 2026 |
| NCT05552755 | Recruiting | Phase 1/Phase 2 | Evaluate REC-4881 in Patients With FAP | July 10, 2023 | July 2026 |
| NCT06163365 | Recruiting | Inherited Cancer Early Diagnosis (ICED) Study | July 26, 2022 | July 26, 2025 | |
| NCT01052376 | Terminated | N/A | Endomicrocancer: Confocal Endomicroscopy in Patients With High Risk of Colorectal Cancer | December 2008 | January 2011 |
| NCT02374931 | Terminated | Early Phase 1 | 18F-FES PET/CT in Imaging Patients With Desmoid Tumors | April 2015 | December 2017 |
| NCT00663819 | Terminated | N/A | Bioabsorbable Staple Line Reinforcement in Colorectal,Coloanal and Ileoanal Anastomoses | April 2008 | October 2012 |
| NCT04709445 | Unknown status | N/A | Perfusion Rate Assessment by Near-infrared Fluorescence in Gastrointestinal Anastomoses | March 1, 2020 | December 2021 |
| NCT03061591 | Unknown status | Phase 2 | Turmeric Supplementation on Polyp Number and Size in Patients With Familial Adenomatous Polyposis. | April 2017 | April 2020 |
| NCT04296851 | Unknown status | Phase 2 | Niclosamide for Familial Adenomatous Polyposis | February 14, 2020 | February 2023 |
| NCT04454151 | Unknown status | Phase 4 | Azithromycin Treatment for Readthrough of APC Gene Stop Codon Mutations in Familial Adenomatous Polyposis | August 1, 2020 | April 1, 2022 |
| NCT02656134 | Unknown status | Small Bowel Endoscopic Evaluation in Familial Adenomatous Polyposis (FAP) | March 2015 | December 2016 | |
| NCT00253812 | Unknown status | N/A | Adenoma Detection Rate:NBI, AFI, Chromoscopic or Standard Endoscopy | November 2005 | |
| NCT04695184 | Unknown status | N/A | Subjective Near-infrared Fluorescence Guidance in Perfusion Assessment of Ileal Pouch Formation and Ileal-pouch-anal Anastomosis | February 1, 2019 | January 2021 |
| NCT04695964 | Unknown status | N/A | Objective Perfusion Rate Assessment by Near-infrared Fluorescence in Ileal Pouch Formation and Ileal-pouch-anal Anastomosis | February 1, 2019 | January 2021 |
| NCT01245816 | Withdrawn | Phase 3 | A Trial of Low Dose Sulindac Combined With Eflornithine in Patients With Familial Adenomatous Polyposis (FAP) | March 2011 | June 2013 |
| NCT00248053 | Withdrawn | Phase 2 | Use of Curcumin in the Lower Gastrointestinal Tract in Familial Adenomatous Polyposis Patients | November 2005 |
- Disase is a (Disease Ontology)
- DOID:5295
- Cross Reference ID (Disease Ontology)
- GARD:6408
- Cross Reference ID (Disease Ontology)
- MESH:D011125
- Cross Reference ID (Disease Ontology)
- MIM:PS175100
- Cross Reference ID (Disease Ontology)
- NCI:C3339
- Cross Reference ID (Disease Ontology)
- ORDO:733
- Cross Reference ID (Disease Ontology)
- SNOMEDCT_US_2023_03_01:72900001
- Cross Reference ID (Disease Ontology)
- UMLS_CUI:C0032580
- Exact Synonym (Disease Ontology)
- adenomatous polyposis of the colon
- OMIM Phenotype Series Number (OMIM)
- PS175100
- OrphaNumber from OrphaNet (Orphanet)
- 733