Pleural Mesothelioma

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Information
Disease name
Pleural Mesothelioma
Disease ID
Description
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
Genes Mutation Description Source Links
NCT ID Status Phase Summary Start date Completion date
NCT04334759 Active, not recruiting Phase 3 DuRvalumab With chEmotherapy as First Line treAtment in Advanced Pleural Mesothelioma February 18, 2021 December 2025
NCT04914897 Active, not recruiting Phase 2 A Study of SAR444245 Combined With Other Anticancer Therapies for the Treatment of Participants With Lung Cancer or Mesothelioma (Pegathor Lung 202) September 23, 2021 January 22, 2025
NCT04040231 Active, not recruiting Phase 1 Using a Targeted Cancer Vaccine (Galinpepimut-S) With Immunotherapy (Nivolumab) in Mesothelioma July 24, 2019 July 2024
NCT00299962 Completed Phase 1 Gene Therapy for Pleural Malignancies March 2006 October 2009
NCT04430842 Completed Phase 1 Dose Escalation Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of QBS10072S July 20, 2020 December 22, 2022
NCT01160458 Completed Phase 2 Phase II Study of IMC-A12 in Patients With Mesothelioma Who Have Been Previously Treated With Chemotherapy June 2, 2010 February 24, 2017
NCT02414945 Completed Phase 1/Phase 2 TILs & Low-Dose IL-2 Therapy Following Cyclophosphamide and Fludarabine in Pleural Mesothelioma Patients May 15, 2015 October 2020
NCT02585362 Completed N/A Whey Protein Supplement in Combination With Physical Exercise and Nutrition Program March 2016 October 2018
NCT04324437 Completed N/A eRAPID: Online Symptom Reporting in Lung Cancer July 20, 2020 December 31, 2023
NCT02899195 Completed Phase 2 Phase II MEDI4736 in Combination With Chemotherapy for First-Line Treatment of Unresectable Mesothelioma June 13, 2017 June 29, 2023
NCT00165516 Completed Phase 2 Extrapleural Pneumonectomy With Intraoperative Intrathoracic/Intraperitoneal Heated Cisplatin With Amifostine and Sodium Thiosulfate January 2004 December 2009
NCT00165555 Completed Phase 1 Pleurectomy/Decortication Followed by Intrathoracic/Intraperitoneal Heated Cisplatin for Malignant Pleural Mesothelioma August 1999 November 2009
NCT06416930 Not yet recruiting Phase 2 Study of Cadonilimab Combined With Chemotherapy in Recurrent / Refractory Pleural Mesothelioma June 20, 2024 June 20, 2029
NCT06155279 Not yet recruiting Phase 2 Induction Chemo+Immunotherapy in Resectable Epithelioid and Biphasic Pleural Mesothelioma (CHIMERA Study) June 2024 December 2026
NCT05538806 Recruiting TTFields in General Routine Clinical Care in Patients With Pleural Mesothelioma Study August 1, 2023 March 31, 2028
NCT05714553 Recruiting Phase 1/Phase 2 NUC-3373 in Combination With Other Agents in Patients With Advanced Solid Tumours March 8, 2023 January 2025
NCT05910112 Recruiting Prospective Data Collection on Clinical, Radiological and Patient Reported Outcomes After Pleural Intervention September 1, 2020 August 1, 2024
NCT05930665 Recruiting Phase 2 Study of Cadonilimab Combined With Bevacizumab and Standard Chemotherapy as First Line Therapy in Unresectable Pleural Mesothelioma November 1, 2023 July 2026
NCT02707666 Recruiting Phase 1 A Pilot Window-Of-Opportunity Study of the Anti-PD-1 Antibody Pembrolizumab in Patients With Resectable Malignant Pleural Mesothelioma February 25, 2016 December 20, 2025
NCT04823741 Recruiting Molecular, Pathologic Intra Tumoral Heterogeneity in Malignant Pleural Mesothelioma February 11, 2022 February 11, 2026
NCT06410625 Recruiting N/A Evaluation of Response by FLT PET in Mesothelioma April 1, 2024 July 1, 2025
NCT06362369 Recruiting Phase 1/Phase 2 A Study of Oral 7HP349 (Alintegimod) in Combination With Ipilimumab Followed by Nivolumab Monotherapy May 20, 2024 December 31, 2028
NCT05086692 Recruiting Phase 1/Phase 2 A Beta-only IL-2 ImmunoTherapY Study August 27, 2021 December 30, 2026
NCT05628376 Recruiting TRAcking Thoracic Cancer Evolution Through Therapy (Rx) EVO December 4, 2023 May 2034
NCT05337735 Suspended Phase 2 A Phase II Clinical Trial to Evaluate Safety and Efficacy of XmAb20717 in Advanced Rare Cancers August 5, 2022 April 1, 2025
NCT04042480 Terminated Phase 1 A Study of SGN-CD228A in Advanced Solid Tumors September 3, 2019 March 9, 2023
NCT04106973 Terminated Mesothelioma Early Detection by VOCs June 5, 2019 January 1, 2022
NCT00895648 Terminated Phase 2 Pemetrexed (ALIMTA) Plus Cisplatin Followed by Surgery and Radiation Therapy for Mesothelioma January 2009 October 2012
NCT00859495 Terminated Phase 2 Trimodal Lung-Sparing Treatment of Pleural Mesothelioma February 2008 February 2012
NCT00165503 Terminated Phase 2 Pleurectomy/Decortication With Intraoperative Intrathoracic/Intraperitoneal Heated Cisplatin With Sodium Thiosulfate April 2004 July 2010
NCT05077111 Unknown status Phase 4 A Comparative Study Between Regional Anesthesia in Thoracoscopes and the Conventional General Anesthesia January 15, 2020 October 15, 2021
NCT02588131 Unknown status Phase 2 A Study of Tremelimumab Combined With the Anti-PD-L1 MEDI4736 Antibody in Malignant Mesothelioma (NIBIT-MESO-1) October 2015 March 2018
NCT03210298 Unknown status International Registry of Patients Treated With Pressurized IntraPeritoneal Aerosol Chemotherapy (PIPAC) January 2016 September 2022
HPO Human Phenotype ID (Human Phenotype Ontology)
HP:0100002
OrphaNumber from OrphaNet (Orphanet)
50251