Locally Advanced Malignant Neoplasm

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Information
Disease name
Locally Advanced Malignant Neoplasm
Disease ID
Description
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
Genes Mutation Description Source Links
NCT ID Status Phase Summary Start date Completion date
NCT03671226 Active, not recruiting N/A Preference of Room Setting and Waiting Time in Patients With Advanced, Locally Advanced, or Metastatic Cancer and Their Caregivers Who Are Seen in the Outpatient Supportive/Palliative Care Center September 28, 2018 December 31, 2024
NCT03743649 Active, not recruiting Phase 2/Phase 3 Haloperidol and Lorazepam in Controlling Symptoms of Persistent Agitated Delirium in Patients With Advanced Cancer Undergoing Palliative Care July 17, 2019 December 31, 2026
NCT04053517 Active, not recruiting Financial Distress in Advanced Cancer Patients July 2, 2019 December 31, 2024
NCT03856060 Active, not recruiting N/A Videos and Questionnaires in Assessing Patient Perception of Physician's Compassion, Communication Skills, and Professionalism During Clinic Visits March 30, 2019 January 31, 2026
NCT04223102 Active, not recruiting N/A Microbiome and Rectal Cancer February 18, 2020 June 2027
NCT03021486 Active, not recruiting Phase 2/Phase 3 Haloperidol With or Without Chlorpromazine in Treating Delirium in Patients With Advanced, Metastatic, or Recurrent Cancer June 5, 2017 June 30, 2025
NCT03595813 Active, not recruiting N/A Identifying Immune-related Biomarkers to Predict the Efficacy of Cancer Immunotherapy January 29, 2018 July 2025
NCT03619668 Active, not recruiting Chemo-radiotherapy as Main Treatment Strategy for Rectal Cancer. Can we Provide a More Precise and Effective Treatment June 29, 2018 March 1, 2025
NCT01325558 Completed Phase 1 A Study of ALT-836 in Combination With Gemcitabine for Locally Advanced or Metastatic Solid Tumors May 2011 February 2015
NCT01847001 Completed Phase 2 Study of Propranolol in Newly Diagnosed Breast Cancer Patients Undergoing Neoadjuvant Chemotherapy October 2012 October 16, 2019
NCT01143974 Completed Phase 4 Trial of Pemetrexed in Combined With Cisplatin for the Treatment of Advanced Breast Cancer June 2010 June 2012
NCT01876927 Completed Phase 2 Pre-Operative Or Peri-Operative Dox Regimen In Patients With Locally Advanced Resectable Gastric Cancer September 2010 March 2017
NCT01903083 Completed Phase 1 Chemoimmunotherapy and Radiation in Pancreatic Cancer July 2013 December 2017
NCT01973673 Completed N/A Healthy Bones Study September 2013 March 1, 2017
NCT02227082 Completed Phase 1 Olaparib and Radiotherapy in Inoperable Breast Cancer October 21, 2013 August 2020
NCT01333709 Completed Phase 2 Multicenter Phase 2 Trial: a Tailored Strategy for Locally Advanced Rectal Carcinoma May 2011 September 2014
NCT04186884 Completed Caregiver Burden, Quality of Life, and Symptom Distress at Different Palliative Cancer Care Settings March 26, 2019 November 5, 2021
NCT02469922 Completed N/A Positron Emission Tomography (PET) During Radio-chemotherapy to Treat Otorhinolaryngological Cancer June 2014 January 29, 2021
NCT02672865 Completed Phase 1 Adjuvant Hyperthermic Intraperitoneal Chemotherapy for Locally Advanced Gastric Cancer February 2, 2016 October 3, 2018
NCT02823652 Completed N/A Pre-Test Genetic Education and Remote Genetic Counseling in Communicating Tumor Profiling Results to Patients With Advanced Cancer October 25, 2016 December 26, 2019
NCT01434394 Completed Phase 2/Phase 3 Neoadjuvant Erbitux Based Chemotherapy for Locally Advanced Oral/Oropharyngeal Cancer August 2011 February 2017
NCT03108131 Completed Phase 2 Cobimetinib and Atezolizumab in Treating Participants With Advanced or Refractory Rare Tumors April 7, 2017 April 2, 2024
NCT01365156 Completed Phase 3 Extraperitoneal Para-aortic Lymph Node Dissection (EPLND) for Cervix August 2011 January 24, 2020
NCT03238027 Completed Phase 1 A Phase 1 Study to Investigate Axatilimab Alone or in Combination With Durvalumab in Patients With Solid Tumors September 1, 2017 November 20, 2020
NCT01440270 Completed Phase 2 Neo-adjuvant Erbitux-based Chemotherapy for Locally Advanced Oral/Oropharyngeal Cancer August 2011 February 2017
NCT03051152 Not yet recruiting N/A D1 Versus D2 Lymphadenectomy in High Risk Elderly With Gastric Adenocarcinoma March 1, 2017 December 31, 2025
NCT04749108 Recruiting Phase 2/Phase 3 Study Evaluating the Tailored Management of Locally-advanced Rectal Carcinoma November 26, 2021 August 2027
NCT03815903 Recruiting Phase 3 Induction Chemotherapy for Locally Advanced Head and Neck Squamous Cell Carcinoma December 19, 2018 December 2025
NCT04260802 Recruiting Phase 1/Phase 2 A Study to Evaluate the Safety and Pharmacokinetics of OC-001 in Patients With Locally Advanced or Metastatic Cancers October 6, 2020 September 30, 2026
NCT03240861 Terminated Phase 1 Genetically Engineered PBMC and PBSC Expressing NY-ESO-1 TCR After a Myeloablative Conditioning Regimen to Treat Patients With Advanced Cancer July 26, 2017 October 19, 2023
NCT01836432 Terminated Phase 3 Immunotherapy Study in Borderline Resectable or Locally Advanced Unresectable Pancreatic Cancer May 2013 March 24, 2017
NCT02236936 Terminated Phase 3 Parenteral Nutrition for Patients Treated for Locally Advanced Inoperable Tumors of the Head and Neck February 3, 2017 July 10, 2019
NCT03170115 Terminated Phase 2 Induction Chemotherapy Plus Chemoradiotherapy With or Without Aspirin in High Risk Rectal Cancer November 30, 2017 January 17, 2020
NCT03295942 Terminated Phase 1 A Study of OMP-336B11 in Subjects With Locally Advanced or Metastatic Tumors September 12, 2017 July 4, 2019
NCT01871363 Unknown status Phase 2 Phase II Study of Preoperative IMRT Combined With Capecitabine and Bevacizumab in Locally Advanced Rectal Cancer October 2012
NCT04112836 Unknown status Pancreatic Cancer Malnutrition and Pancreatic Exocrine Insufficiency in the Course of Chemotherapy in Unresectable Pancreatic Cancer March 15, 2019 August 2020
NCT02404051 Unknown status Phase 3 Fulvestrant and EVerolimus Plus EXemestane in Metastatic Breast Cancer December 2015 January 2019
NCT05099809 Unknown status Registry Trial to Evaluate the Safety and Efficacy of Hyperthermia in Locally Advanced Cancers December 1, 2021 June 30, 2023
NCT01675999 Unknown status Phase 2 Trial of Neoadjuvant Chemotherapy in Locally Advanced Colon Cancer May 2012 February 2021
NCT01566799 Unknown status Phase 2 Metformin Plus Neoadjuvant Chemotherapy in Breast Cancer April 2012 April 2014
NCT03849742 Withdrawn N/A Ride to Care - Quality of Life With Transportation for RT May 15, 2019 December 31, 2024