Plasmodium falciparum infection

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Information
Disease name
Plasmodium falciparum infection
Disease ID
Description
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
Genes Mutation Description Source Links
NCT ID Status Phase Summary Start date Completion date
NCT05304611 Active, not recruiting Phase 2 Anti-malaria MAb in Malian Children March 18, 2022 April 2024
NCT00379821 Completed Phase 3 Chloroquine Alone or in Combination for Malaria in Children in Malawi February 2007 September 2012
NCT00744133 Completed Phase 1 Malaria Challenge With NF54 Strain March 2009 November 2011
NCT02020330 Completed Phase 3 Optimising Operational Use of Artemether-lumefantrine Comparing 3 Day Versus 5 Day November 25, 2013 March 25, 2015
NCT02143934 Completed Phase 4 Effect of Liver and Blood-stage Treatment on Subsequent Plasmodium Reinfection and Morbidity August 2009 May 2014
NCT02353494 Completed Efficacy and Safety of Dihydroartemisinin-piperaquine (DHP) for the Treatment of Uncomplicated Malaria March 2015 May 2016
NCT05816330 Completed Phase 2 L9LS MAb in Malian Adults May 25, 2023 February 11, 2024
NCT03168854 Completed Phase 1 Trial to Evaluate the Safety, Immunogenicity and Protective Efficacy of Three or Five Administrations of GAP3KO Sporozoites July 26, 2017 August 16, 2019
NCT03589794 Completed Phase 1 rCSP/AP10-602 [GLA-LSQ] Vaccine Trial December 21, 2018 July 5, 2022
NCT03660839 Completed Phase 2 Study to Investigate the Clinical and Parasiticidal Activity and Pharmacokinetics of Different Doses of Artefenomel and Ferroquine in Patients With Uncomplicated Plasmodium Falciparum Malaria September 11, 2018 November 6, 2019
NCT04329104 Completed Phase 2 Safety and Efficacy of CIS43LS Anti-malaria mAb in Mali February 15, 2021 July 5, 2023
NCT00371189 Completed Phase 1 Adenovirus Vaccine for Malaria January 2007 June 2014
NCT02663700 Completed Phase 1 Safety and Immunogenicity of Sanaria's Irradiated Sporozoite Vaccine (PfSPZ Vaccine) in Malaria-Experienced Adults in Burkina Faso April 7, 2016 December 17, 2018
NCT02773979 Completed Phase 1 PfSPZ Challenge in Healthy Malaria-Naïve Adults in the United States September 12, 2016 January 22, 2018
NCT02780154 Completed Phase 1 PfSPZ Challenge in Non-immune Adults in Baltimore, USA August 25, 2016 December 15, 2016
NCT02996695 Completed Phase 1 Safety and Efficacy of Sanaria's PfSPZ-CVac in Malian Adults April 6, 2017 June 22, 2018
NCT03014258 Completed Phase 1 A Systems Biology Approach to Malaria Immunity June 7, 2017 July 19, 2019
NCT05750459 Recruiting Phase 4 Pharmacokinetic Study of IV Artesunate to Treat Children With Severe Malaria November 29, 2023 December 30, 2024
NCT05400655 Recruiting Phase 2 Anti-malaria MAb in Kenyan Children September 14, 2022 June 30, 2024
NCT02497612 Terminated Phase 2 To Evaluate the Efficacy, Safety, Tolerability and Pharmacokinetics of a Single Dose Regimen of Ferroquine and Artefenomel in Adults and Children With Uncomplicated Plasmodium Falciparum Malaria July 25, 2015 September 23, 2019
NCT00988507 Terminated Phase 2 Dose Ranging Study of Ferroquine With Artesunate in African Adults and Children With Uncomplicated Plasmodium Falciparum Malaria October 2009 November 2010
NCT05025761 Unknown status N/A Reducing Malaria Transmission in Forest-going Mobile and Migrant Populations in Myanmar January 1, 2022 June 2022